| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eun-Jin Bae, He-Jin Lee, Edward Rockenstein, Dong-Hwan Ho, Eun-Bi Park, Na-Young Yang, Paula Desplats, Eliezer Masliah, Seung-Jae Le. Antibody-aided clearance of extracellular α-synuclein prevents cell-to-cell aggregate transmission. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 39. 2012-12-10. PMID:23015436. |
abnormal deposition and intercellular propagation of α-synuclein plays a central role in the pathogenesis of disorders such as parkinson's disease (pd) and dementia with lewy bodies (dlb). |
2012-12-10 |
2023-08-12 |
mouse |
| Pietro-Luca Ratti, Michele Terzaghi, Brigida Minafra, Alessandra Repetto, Chiara Pasotti, Roberta Zangaglia, Claudio Pacchetti, Raffaele Mann. REM and NREM sleep enactment behaviors in Parkinson's disease, Parkinson's disease dementia, and dementia with Lewy bodies. Sleep medicine. vol 13. issue 7. 2012-12-03. PMID:22704402. |
nocturnal sleep enactment behaviors (sebs) are common in patients affected by parkinson's disease (pd), dementia associated with parkinson's disease (pdd), and dementia with lewy bodies (dlb). |
2012-12-03 |
2023-08-12 |
Not clear |
| Kejal Kantarci, Val J Lowe, Bradley F Boeve, Stephen D Weigand, Matthew L Senjem, Scott A Przybelski, Dennis W Dickson, Joseph E Parisi, David S Knopman, Glenn E Smith, Tanis J Ferman, Ronald C Petersen, Clifford R Jac. Multimodality imaging characteristics of dementia with Lewy bodies. Neurobiology of aging. vol 33. issue 9. 2012-11-29. PMID:22018896. |
dementia with lewy bodies (dlb) is the second most common cause of neurodegenerative dementia after alzheimer's disease (ad). |
2012-11-29 |
2023-08-12 |
human |
| Yuhei Chiba, Hiroshige Fujishiro, Eizo Iseki, Kazumi Ota, Koji Kasanuki, Yoshio Hirayasu, Kiyoshi Sato. Retrospective survey of prodromal symptoms in dementia with Lewy bodies: comparison with Alzheimer's disease. Dementia and geriatric cognitive disorders. vol 33. issue 4. 2012-11-29. PMID:22722638. |
it remains unknown when those symptoms appear in dementia with lewy bodies (dlb). |
2012-11-29 |
2023-08-12 |
Not clear |
| Yasushi Iwasaki, Keiko Mori, Masumi Ito, Maya Mimuro, Mari Yoshid. [An autopsied case of dementia with lewy bodies presenting with hemispheric cerebral cortical atrophy with selective neuronal necrosis after status epilepticus]. Brain and nerve = Shinkei kenkyu no shinpo. vol 64. issue 9. 2012-11-29. PMID:22941844. |
we report on a 72-year-old-japanese man with dementia with lewy bodies (dlb) who presented with hemispheric cerebral cortical atrophy with selective neuronal necrosis after status epilepticus. |
2012-11-29 |
2023-08-12 |
Not clear |
| J Wu, H Lou, T N M Alerte, E K Stachowski, J Chen, A B Singleton, R L Hamilton, R G Pere. Lewy-like aggregation of α-synuclein reduces protein phosphatase 2A activity in vitro and in vivo. Neuroscience. vol 207. 2012-11-27. PMID:22326202. |
α-synuclein (α-syn) is a chaperone-like protein that is highly implicated in parkinson's disease (pd) as well as in dementia with lewy bodies (dlb). |
2012-11-27 |
2023-08-12 |
mouse |
| Kejal Kantarci, Chunhui Yang, Julie A Schneider, Matthew L Senjem, Denise A Reyes, Val J Lowe, Lisa L Barnes, Neelum T Aggarwal, David A Bennett, Glenn E Smith, Ronald C Petersen, Clifford R Jack, Bradley F Boev. Antemortem amyloid imaging and β-amyloid pathology in a case with dementia with Lewy bodies. Neurobiology of aging. vol 33. issue 5. 2012-11-23. PMID:20961664. |
the association between ante mortem [(11)c]-pittsburgh compound b (pib) retention and β-amyloid (aβ) load, lewy body (lb) and neurofibrillary tangle (nft) densities were investigated in a pathologically confirmed case of dementia with lewy bodies (dlb). |
2012-11-23 |
2023-08-12 |
Not clear |
| Frédéric Peters, Anne-Marie Ergis, Serge Gauthier, Bénédicte Dieudonné, Marc Verny, Pierre Jolicoeur, Sylvie Bellevill. Abnormal temporal dynamics of visual attention in Alzheimer's disease and in dementia with Lewy bodies. Neurobiology of aging. vol 33. issue 5. 2012-11-23. PMID:22130206. |
although attentional control processes are disproportionately impaired in dementia with lewy bodies (dlb) compared with dementia of the alzheimer type (dat), previous studies have not compared directly the temporal dynamics of visual attention in dlb and dat. |
2012-11-23 |
2023-08-12 |
human |
| Stephen N Gomperts, Joseph J Locascio, Marta Marquie, Andrea L Santarlasci, Dorene M Rentz, Jacqueline Maye, Keith A Johnson, John H Growdo. Brain amyloid and cognition in Lewy body diseases. Movement disorders : official journal of the Movement Disorder Society. vol 27. issue 8. 2012-11-21. PMID:22693110. |
many patients with pd develop pd with dementia (pdd), a syndrome that overlaps clinically and pathologically with dementia with lewy bodies (dlb); pdd and dlb differ chiefly in the relative timing of dementia and parkinsonism. |
2012-11-21 |
2023-08-12 |
human |
| Stephen N Gomperts, Joseph J Locascio, Marta Marquie, Andrea L Santarlasci, Dorene M Rentz, Jacqueline Maye, Keith A Johnson, John H Growdo. Brain amyloid and cognition in Lewy body diseases. Movement disorders : official journal of the Movement Disorder Society. vol 27. issue 8. 2012-11-21. PMID:22693110. |
brain amyloid deposition is an early feature of dlb and may account, in part, for its early dementia. |
2012-11-21 |
2023-08-12 |
human |
| Stephen N Gomperts, Joseph J Locascio, Marta Marquie, Andrea L Santarlasci, Dorene M Rentz, Jacqueline Maye, Keith A Johnson, John H Growdo. Brain amyloid and cognition in Lewy body diseases. Movement disorders : official journal of the Movement Disorder Society. vol 27. issue 8. 2012-11-21. PMID:22693110. |
early amyloid deposits in dlb relative to pdd may account for their difference in the timing of dementia and parkinsonism. |
2012-11-21 |
2023-08-12 |
human |
| Hiroshige Fujishiro, Shinichiro Nakamura, Maiko Kitazawa, Kiyoshi Sato, Eizo Isek. Early detection of dementia with Lewy bodies in patients with amnestic mild cognitive impairment using 123I-MIBG cardiac scintigraphy. Journal of the neurological sciences. vol 315. issue 1-2. 2012-11-20. PMID:22129938. |
increasing clinical attention has been focused on cardiac sympathetic denervation for the differential diagnosis of dementia with lewy bodies (dlb) from alzheimer's disease (ad) with the development of [123i] metaiodobenzylguanidine (mibg) scintigraphy. |
2012-11-20 |
2023-08-12 |
Not clear |
| Richard A Armstron. β-amyloid (Aβ) deposition in cognitively normal brain, dementia with Lewy bodies, and Alzheimer's disease: a study using principal components analysis. Folia neuropathologica. vol 50. issue 2. 2012-11-16. PMID:22773458. |
the densities of diffuse, primitive, and classic β-amyloid (aβ) deposits were studied in the temporal lobe in cognitively normal brain, dementia with lewy bodies (dlb), familial alzheimer's disease (fad), and sporadic ad (sad). |
2012-11-16 |
2023-08-12 |
Not clear |
| Jochen Klucken, Anne-Maria Poehler, Darius Ebrahimi-Fakhari, Jacqueline Schneider, Silke Nuber, Edward Rockenstein, Ursula Schlötzer-Schrehardt, Bradley T Hyman, Pamela J McLean, Eliezer Masliah, Juergen Winkle. Alpha-synuclein aggregation involves a bafilomycin A 1-sensitive autophagy pathway. Autophagy. vol 8. issue 5. 2012-11-13. PMID:22647715. |
synucleinopathies like parkinson disease and dementia with lewy bodies (dlb) are characterized by α-synuclein aggregates within neurons (lewy bodies) and their processes (lewy neurites). |
2012-11-13 |
2023-08-12 |
mouse |
| Rosie Watson, Andrew M Blamire, Sean J Colloby, Josh S Wood, Robert Barber, Jiabao He, John T O'Brie. Characterizing dementia with Lewy bodies by means of diffusion tensor imaging. Neurology. vol 79. issue 9. 2012-11-07. PMID:22895591. |
to investigate patterns of in vivo white matter tract change using diffusion tensor imaging (dti), we conducted a cross-sectional study of dementia with lewy bodies (dlb) in comparison with alzheimer disease (ad) and normal aging. |
2012-11-07 |
2023-08-12 |
Not clear |
| Alessandro Stefani, Livia Brusa, Enrica Olivola, Mariangela Pierantozzi, Alessandro Martoran. CSF and clinical hallmarks of subcortical dementias: focus on DLB and PDD. Journal of neural transmission (Vienna, Austria : 1996). vol 119. issue 7. 2012-11-06. PMID:22622365. |
csf and clinical hallmarks of subcortical dementias: focus on dlb and pdd. |
2012-11-06 |
2023-08-12 |
Not clear |
| Alessandro Stefani, Livia Brusa, Enrica Olivola, Mariangela Pierantozzi, Alessandro Martoran. CSF and clinical hallmarks of subcortical dementias: focus on DLB and PDD. Journal of neural transmission (Vienna, Austria : 1996). vol 119. issue 7. 2012-11-06. PMID:22622365. |
whether pd with dementia (pdd) and dementia with lewy bodies (dlb) represent further steps along with a continuum of the same progressive degeneration due to lewy bodies deposition, rather then the association of lewy bodies and aβ pathology, remains a challenging issue. |
2012-11-06 |
2023-08-12 |
Not clear |
| Alessandro Stefani, Livia Brusa, Enrica Olivola, Mariangela Pierantozzi, Alessandro Martoran. CSF and clinical hallmarks of subcortical dementias: focus on DLB and PDD. Journal of neural transmission (Vienna, Austria : 1996). vol 119. issue 7. 2012-11-06. PMID:22622365. |
our conclusions are that the csf pattern, in pdd and dlb, can certainly be distinct from that in ad, though mechanisms leading to dementia could be shared among them. |
2012-11-06 |
2023-08-12 |
Not clear |
| Etsuro Mori, Manabu Ikeda, Kenji Kosak. Donepezil for dementia with Lewy bodies: a randomized, placebo-controlled trial. Annals of neurology. vol 72. issue 1. 2012-10-24. PMID:22829268. |
because cholinergic deficits are prominent in dementia with lewy bodies (dlb), we investigated the effects of a cholinesterase inhibitor, donepezil, in such patients in a randomized, double-blind, placebo-controlled exploratory phase 2 trial. |
2012-10-24 |
2023-08-12 |
Not clear |
| Kenji Kosak. [Dementia with Lewy bodies (DLB): general remarks]. Nihon rinsho. Japanese journal of clinical medicine. vol 69 Suppl 10 Pt 2. 2012-10-19. PMID:22755210. |
[dementia with lewy bodies (dlb): general remarks]. |
2012-10-19 |
2023-08-12 |
Not clear |