| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R W Warzok, C Kessler, G Apel, A Schwarz, R Egensperger, D Schreiber, E W Herbst, E Wolf, R Walther, L C Walke. Apolipoprotein E4 promotes incipient Alzheimer pathology in the elderly. Alzheimer disease and associated disorders. vol 12. issue 1. 1998-05-14. PMID:9539408. |
to evaluate the influence of the apolipoprotein e (apoe) epsilon4 allele on the age at which alzheimer-like lesions appear in the brain, we analyzed the degree of cerebral beta-amyloidosis and neurofibrillary tangle formation in the hippocampal formation and adjacent cortical areas 28, 27, and 36 of persons who had died between the ages of 50 and 93 years and who had shown no signs of clinical dementia. |
1998-05-14 |
2023-08-12 |
Not clear |
| R Inzelberg, J Chapman, T A Treves, A Asherov, S Kipervasser, O Hilkewicz, R Verchovsky, S Klimowitzky, A D Korczy. Apolipoprotein E4 in Parkinson disease and dementia: new data and meta-analysis of published studies. Alzheimer disease and associated disorders. vol 12. issue 1. 1998-05-14. PMID:9539410. |
the authors examined whether the epsilon4 allele might be associated with dementia in parkinson disease (pd), given that the dementia of pd shares neuroanatomic and neurochemical features with alzheimer disease (ad) and that many recent studies have found a high prevalence of the epsilon4 allele of apolipoprotein e (apoe) in ad. |
1998-05-14 |
2023-08-12 |
Not clear |
| A L Bergem, L Lannfel. Apolipoprotein E type epsilon4 allele, heritability and age at onset in twins with Alzheimer disease and vascular dementia. Clinical genetics. vol 52. issue 5. 1998-04-24. PMID:9520135. |
the apolipoprotein e (apoe) epsilon4 allele is a risk factor in alzheimer disease (ad), but not in vascular dementia (vad). |
1998-04-24 |
2023-08-12 |
Not clear |
| J G Sayi, N B Patel, D R Premkumar, A Adem, B Winblad, W B Matuja, E P Mtui, S Gatere, R P Friedland, E Koss, R N Kalari. Apolipoprotein E polymorphism in elderly east Africans. East African medical journal. vol 74. issue 10. 1998-04-23. PMID:9529753. |
the association of apoe allele frequencies and dementia remain unknown in populations from developing countries. |
1998-04-23 |
2023-08-12 |
human |
| B Schmand, C Hooijer, C Jonker, J Lindeboom, L M Haveke. Apolipoprotein E phenotype is not related to late-life depression in a population-based sample. Social psychiatry and psychiatric epidemiology. vol 33. issue 1. 1998-03-19. PMID:9448441. |
the relation of apoe epsilon 4 with dementia and with various types of late-life depression was studied. |
1998-03-19 |
2023-08-12 |
Not clear |
| B Schmand, C Hooijer, C Jonker, J Lindeboom, L M Haveke. Apolipoprotein E phenotype is not related to late-life depression in a population-based sample. Social psychiatry and psychiatric epidemiology. vol 33. issue 1. 1998-03-19. PMID:9448441. |
it was expected that apoe epsilon 4 allele frequencies would be elevated not only in alzheimer's disease and dementia in general, but also in first episode, late-life depression accompanied by subtle cognitive impairment (possibly organic depression). |
1998-03-19 |
2023-08-12 |
Not clear |
| H Lamb, J Christie, A B Singleton, A Leake, R H Perry, P G Ince, I G McKeith, L M Melton, J A Edwardson, C M Morri. Apolipoprotein E and alpha-1 antichymotrypsin polymorphism genotyping in Alzheimer's disease and in dementia with Lewy bodies. Distinctions between diseases. Neurology. vol 50. issue 2. 1998-03-16. PMID:9484359. |
we tested this possibility by genotyping a large series of clinically and neuropathologically confirmed cases of ad and a series of cases with dementia with lewy bodies (dlb) with a matched control group for the aact locus and apoe. |
1998-03-16 |
2023-08-12 |
Not clear |
| T Muramatsu, M Kato, T Matsui, H Yoshimasu, A Yoshino, S Matsushita, S Higuchi, H Kashim. Apolipoprotein E epsilon 4 allele distribution in Wernicke-Korsakoff syndrome with or without global intellectual deficits. Journal of neural transmission (Vienna, Austria : 1996). vol 104. issue 8-9. 1998-02-26. PMID:9451723. |
these results added further support to the notion that the consequence of acute insult to the brain is influenced by the apoe genotype, and suggested apoe's role in the development of a certain group of "alcoholic dementia." |
1998-02-26 |
2023-08-12 |
Not clear |
| T Tapiola, M Lehtovirta, J Ramberg, S Helisalmi, K Linnaranta, P Riekkinen, H Soinine. CSF tau is related to apolipoprotein E genotype in early Alzheimer's disease. Neurology. vol 50. issue 1. 1998-02-06. PMID:9443475. |
this study shows that the current elisa test for csf tau is not sensitive and specific enough to distinguish early ad from other dementias and indicates that in the interpretation of csf tau analysis as a diagnostic tool, the apoe genotype should also be taken into account. |
1998-02-06 |
2023-08-12 |
human |
| Y Forsell, E H Corder, H Basun, L Lannfelt, M Viitanen, B Winbla. Depression and dementia in relation to apolipoprotein E polymorphism in a population sample age 75+. Biological psychiatry. vol 42. issue 10. 1998-02-05. PMID:9359975. |
the aim of this study was to define the co-occurrence of depression and dementia in relation to apolipoprotein e (apoe) polymorphism. |
1998-02-05 |
2023-08-12 |
human |
| Y Forsell, E H Corder, H Basun, L Lannfelt, M Viitanen, B Winbla. Depression and dementia in relation to apolipoprotein E polymorphism in a population sample age 75+. Biological psychiatry. vol 42. issue 10. 1998-02-05. PMID:9359975. |
in spite of the association between dementia and apoe polymorphism, as well as dementia and depression, there was no association between apoe polymorphism and depression. |
1998-02-05 |
2023-08-12 |
human |
| I Skoog, C Hesse, O Aevarsson, S Landahl, J Wahlström, P Fredman, K Blenno. A population study of apoE genotype at the age of 85: relation to dementia, cerebrovascular disease, and mortality. Journal of neurology, neurosurgery, and psychiatry. vol 64. issue 1. 1998-01-30. PMID:9436725. |
to study the association of apoe genotypes with dementia and cerebrovascular disorders in a population based sample of 85 year old people. |
1998-01-30 |
2023-08-12 |
Not clear |
| M J Bullido, M J Artiga, M Recuero, I Sastre, M A García, J Aldudo, C Lendon, S W Han, J C Morris, A Frank, J Vázquez, A Goate, F Valdivies. A polymorphism in the regulatory region of APOE associated with risk for Alzheimer's dementia. Nature genetics. vol 18. issue 1. 1998-01-29. PMID:9425904. |
a polymorphism in the regulatory region of apoe associated with risk for alzheimer's dementia. |
1998-01-29 |
2023-08-12 |
Not clear |
| T J Montine, K S Montine, L L Swif. Central nervous system lipoproteins in Alzheimer's disease. The American journal of pathology. vol 151. issue 6. 1998-01-02. PMID:9403708. |
alzheimer's disease (ad) is the most common form of dementia in the united states and has been associated with apoe genotype. |
1998-01-02 |
2023-08-12 |
Not clear |
| C Bancher, R Egensperger, S Kösel, K Jellinger, M B Graebe. Low prevalence of apolipoprotein E epsilon 4 allele in the neurofibrillary tangle predominant form of senile dementia. Acta neuropathologica. vol 94. issue 5. 1997-12-30. PMID:9386771. |
the low prevalence of the apoe epsilon 4 allele in this subset of patients is striking and suggests that nft-predominant senile dementia is a dementing neurodegenerative disease in which the deposition of a beta-amyloid did not occur, possibly due to protective effects of epsilon 2 and/or epsilon 3 alleles or lack of a promoting effect of apoe epsilon 4 on amyloidogenesis. |
1997-12-30 |
2023-08-12 |
Not clear |
| V P Prasher, T A Chowdhury, B R Rowe, S C Bai. ApoE genotype and Alzheimer's disease in adults with Down syndrome: meta-analysis. American journal of mental retardation : AJMR. vol 102. issue 2. 1997-12-15. PMID:9327086. |
the apoe gene polymorphism was examined in 100 adults with down syndrome (with and without dementia) compared to 346 control subjects without mental retardation. |
1997-12-15 |
2023-08-12 |
human |
| V P Prasher, T A Chowdhury, B R Rowe, S C Bai. ApoE genotype and Alzheimer's disease in adults with Down syndrome: meta-analysis. American journal of mental retardation : AJMR. vol 102. issue 2. 1997-12-15. PMID:9327086. |
although no significant association between possession of the apoe epsilon 4 allele and onset of alzheimer's disease was found, subjects with the allele had a tendency towards lower age of onset of dementia. |
1997-12-15 |
2023-08-12 |
human |
| V P Prasher, T A Chowdhury, B R Rowe, S C Bai. ApoE genotype and Alzheimer's disease in adults with Down syndrome: meta-analysis. American journal of mental retardation : AJMR. vol 102. issue 2. 1997-12-15. PMID:9327086. |
subjects with apoe epsilon 2 allele may not develop dementia and may have increased longevity. |
1997-12-15 |
2023-08-12 |
human |
| A D Roses, A M Saunder. ApoE, Alzheimer's disease, and recovery from brain stress. Annals of the New York Academy of Sciences. vol 826. 1997-11-13. PMID:9329691. |
the risk of stroke and vascular dementia has not been confirmed in neuropathological series to be related to specific apoe genotypes. |
1997-11-13 |
2023-08-12 |
human |
| K Beyer, J I Lao, L Fernández-Novoa, X A Alvarez, M A Sellers, R Cacabelo. APOE epsilon 4 allele frequency in Alzheimer's disease and vascular dementia in the Spanish population. Annals of the New York Academy of Sciences. vol 826. 1997-11-13. PMID:9329722. |
apoe epsilon 4 allele frequency in alzheimer's disease and vascular dementia in the spanish population. |
1997-11-13 |
2023-08-12 |
Not clear |