Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
A L Svensson, U Warpman, E Hellström-Lindahl, N Bogdanovic, L Lannfelt, A Nordber. Nicotinic receptors, muscarinic receptors and choline acetyltransferase activity in the temporal cortex of Alzheimer patients with differing apolipoprotein E genotypes. Neuroscience letters. vol 232. issue 1. 1997-10-23. PMID:9292886. |
a significant negative correlation (p < 0.001) was observed in ad brains between the histopathological dementia score and chat activity, which was independent of the apoe genotype. |
1997-10-23 |
2023-08-12 |
Not clear |
P Johannsen, J K Jakobsen, A L Jørgense. [Apolipoprotein E genotypes in patients investigated for dementia]. Ugeskrift for laeger. vol 159. issue 38. 1997-10-21. PMID:9340872. |
we present the distribution of the apoe alleles (e2, e3 and e4) in 50 danish patients referred to a dementia clinic. |
1997-10-21 |
2023-08-12 |
Not clear |
K A Welsh-Bohmer, M Gearing, A M Saunders, A D Roses, S Mirr. Apolipoprotein E genotypes in a neuropathological series from the Consortium to Establish a Registry for Alzheimer's Disease. Annals of neurology. vol 42. issue 3. 1997-10-16. PMID:9307253. |
in the 162 patients for whom autopsy and apoe genotype data were available, the clinical diagnosis of ad was verified as the primary cause of dementia in 139 cases (139 of 162, or 86%). |
1997-10-16 |
2023-08-12 |
Not clear |
B Nacmias, A Tedde, B M Guarnieri, C Petruzzi, L Ortenzi, A Serio, L Amaducci, S Sorb. Analysis of apolipoprotein E, alpha1-antichymotrypsin and presenilin-1 genes polymorphisms in dementia caused by normal pressure hydrocephalus in man. Neuroscience letters. vol 229. issue 3. 1997-09-24. PMID:9237487. |
apolipoprotein e (apoe) epsilon4 allele has been associated with severity of dementia in alzheimer's disease (ad) and in other forms of dementia. |
1997-09-24 |
2023-08-12 |
Not clear |
M Lindh, M Blomberg, M Jensen, H Basun, L Lannfelt, B Engvall, H Scharnagel, W März, L O Wahlund, R F Cowbur. Cerebrospinal fluid apolipoprotein E (apoE) levels in Alzheimer's disease patients are increased at follow up and show a correlation with levels of tau protein. Neuroscience letters. vol 229. issue 2. 1997-09-16. PMID:9223597. |
apolipoprotein e (apoe) levels were compared in cerebrospinal fluid (csf) taken on two occasions, with an average 15 months follow up, from groups of patients with alzheimer's disease (ad: n = 18), mild cognitive impairment (mci; n = 9) and other dementia disorders (odd; n = 9). |
1997-09-16 |
2023-08-12 |
Not clear |
G E Alexander, A M Saunders, J Szczepanik, T L Strassburger, P Pietrini, A Dani, M L Furey, M J Mentis, A D Roses, S I Rapoport, M B Schapir. Relation of age and apolipoprotein E to cognitive function in Down syndrome adults. Neuroreport. vol 8. issue 8. 1997-08-29. PMID:9223061. |
the relationship between basic linguistic skills and apoe genotype supports this genetic factor in influencing the development of dementia and ad neuropathology in ds. |
1997-08-29 |
2023-08-12 |
human |
S E Arnold, E Joo, M G Martinoli, N Roy, J Q Trojanowski, R E Gur, T Cannon, R A Pric. Apolipoprotein E genotype in schizophrenia: frequency, age of onset, and neuropathologic features. Neuroreport. vol 8. issue 6. 1997-08-07. PMID:9172167. |
however, the apoe epsilon 4 genotype was associated with a younger age of onset of schizophrenia, and in an elderly subsample, individuals with the epsilon 4 allele more frequently exhibited co-existent dementia and had more neurofibrillary pathology (although none of the cases met criteria for alzheimer's disease). |
1997-08-07 |
2023-08-12 |
Not clear |
H Arai, S Higuchi, H Sasak. Apolipoprotein E genotyping and cerebrospinal fluid tau protein: implications for the clinical diagnosis of Alzheimer's disease. Gerontology. vol 43 Suppl 1. 1997-08-04. PMID:9187933. |
apolipoprotein e (apoe) genotyping was conducted in sporadic alzheimer's disease (ad, n = 91) as well as in other dementing disorders including parkinson's disease (pd, n = 73), autopsy-confirmed diffuse lewy body disease (dlbd, n = 16), progressive supranuclear palsy (n = 13), vascular dementia (n = 55), alcoholic dementia (n =25) and normal control subjects (n = 77). |
1997-08-04 |
2023-08-12 |
human |
L Minthon, C Hesse, M Sjögren, E Englund, L Gustafson, K Blenno. The apolipoprotein E epsilon4 allele frequency is normal in fronto-temporal dementia, but correlates with age at onset of disease. Neuroscience letters. vol 226. issue 1. 1997-07-21. PMID:9153643. |
the apolipoprotein (apoe) epsilon4 allele was studied in fronto-temporal dementia (ftd), a diagnostic category including the specific disorders pick's disease and frontal lobe degeneration of non-alzheimer type (fld). |
1997-07-21 |
2023-08-12 |
Not clear |
B D Jordan, N R Relkin, L D Ravdin, A R Jacobs, A Bennett, S Gand. Apolipoprotein E epsilon4 associated with chronic traumatic brain injury in boxing. JAMA. vol 278. issue 2. 1997-07-17. PMID:9214529. |
given the similarities between alzheimer disease and dementia pugilistica, we evaluated the relationship between apolipoprotein e (apoe) genotype and chronic traumatic brain injury (ctbi) in boxers to determine whether there is a genetic susceptibility to the effects of head trauma. |
1997-07-17 |
2023-08-12 |
Not clear |
M Stevens, C M van Duijn, P de Knijff, C van Broeckhoven, P Heutink, B A Oostra, M F Niermeijer, J C van Swiete. Apolipoprotein E gene and sporadic frontal lobe dementia. Neurology. vol 48. issue 6. 1997-07-10. PMID:9191760. |
we studied the connection between the apoe gene and the risk and onset of disease in 34 patients with clinically diagnosed frontal lobe dementia (fld) derived from a population-based study in the netherlands. |
1997-07-10 |
2023-08-12 |
Not clear |
D C Steffens, B L Plassman, M J Helms, K A Welsh-Bohmer, A M Saunders, J C Breitne. A twin study of late-onset depression and apolipoprotein E epsilon 4 as risk factors for Alzheimer's disease. Biological psychiatry. vol 41. issue 8. 1997-06-17. PMID:9099411. |
results were similar when the sample was stratified by twin pair, so that a single genetic marker is unlikely to explain the relation among depression, apoe, and dementia. |
1997-06-17 |
2023-08-12 |
Not clear |
M R Farlo. Alzheimer's disease: clinical implications of the apolipoprotein E genotype. Neurology. vol 48. issue 5 Suppl 6. 1997-06-09. PMID:9153158. |
insufficient evidence also exists at this time to recommend apoe genotyping as an adjuvant for the differential diagnosis of dementia or as a possible predictor for response to drug therapy. |
1997-06-09 |
2023-08-12 |
Not clear |
F Pasquier, D Ley. Why are stroke patients prone to develop dementia? Journal of neurology. vol 244. issue 3. 1997-05-29. PMID:9050953. |
secondly, post-stroke dementia may be due to an associated asymptomatic alzheimer pathology; the reasons for such an association are that (1) some cases of dementia occurring after a stroke are progressive and alzheimer's disease (ad) is the most frequent cause of progressive dementia; (2) age and apoe epsilon 4 genotype are risk factors for both ad and ischaemic stroke; (3) a vasculopathy is often associated with ad. |
1997-05-29 |
2023-08-12 |
Not clear |
G S Zubenko, R Henderson, J S Stiffler, S Stabler, J Rosen, B B Kapla. Association of the APOE epsilon 4 allele with clinical subtypes of late life depression. Biological psychiatry. vol 40. issue 10. 1997-05-13. PMID:8915560. |
the apoe genotypes of 45 elderly inpatients with major depression were determined to investigate the relationship of this disorder to irreversible dementia in late life. |
1997-05-13 |
2023-08-12 |
Not clear |
S Higuchi, H Arai, T Nakagawa, T Muramatsu, H Sasaki, J Q Trojanowsk. The apolipoprotein E gene in Binswanger's disease and vascular dementia. Clinical genetics. vol 50. issue 6. 1997-05-09. PMID:9147873. |
the frequency of the epsilon 4 allele of the apoe (apoe4) in bd patients and non-bd vascular dementia patients did not differ from that observed in the nondemented elderly controls, but it was significantly lower than the frequency in ad patients. |
1997-05-09 |
2023-08-12 |
Not clear |
S Higuchi, H Arai, T Nakagawa, T Muramatsu, H Sasaki, J Q Trojanowsk. The apolipoprotein E gene in Binswanger's disease and vascular dementia. Clinical genetics. vol 50. issue 6. 1997-05-09. PMID:9147873. |
these results and other recent observations suggest that one or more factors other than the apoe gene contribute to the pathogenesis of dementia in bd and non-bd vascular dementia. |
1997-05-09 |
2023-08-12 |
Not clear |
D Tsuang, M A Raskind, J Leverenz, E R Peskind, G Schellenberg, T D Bir. The effect of apolipoprotein E genotype on expression of an autosomal dominant schizophreniform disorder with progressive dementia and neurofibrillary tangles. Biological psychiatry. vol 41. issue 2. 1997-04-02. PMID:9018389. |
we examined apoe genotypes and their effects on age of onset in a family with an autosomal dominant "neurofibrillary tangle only" dementia. |
1997-04-02 |
2023-08-12 |
Not clear |
A J Slooter, M X Tang, C M van Duijn, Y Stern, A Ott, K Bell, M M Breteler, C Van Broeckhoven, T K Tatemichi, B Tycko, A Hofman, R Mayeu. Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation. JAMA. vol 277. issue 10. 1997-03-19. PMID:9052712. |
to investigate the association between the apolipoprotein e (apoe) genotypes and dementia in patients with stroke, defined as either vascular dementia (vad) or alzheimer disease with cerebrovascular disease (ad with cvd). |
1997-03-19 |
2023-08-12 |
Not clear |
T A Treves, N M Bornstein, J Chapman, S Klimovitzki, R Verchovsky, A Asherov, I O Veshchev, A D Korczy. APOE-epsilon 4 in patients with Alzheimer disease and vascular dementia. Alzheimer disease and associated disorders. vol 10. issue 4. 1997-02-25. PMID:8939277. |
the apolipoprotein e (apoe) epsilon 4 allele has been consistently found to be frequent in patients with progressive degenerative dementia of the alzheimer type (dat). |
1997-02-25 |
2023-08-12 |
Not clear |