| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yoshimichi Sato, Oliver Schmitt, Zachary Ip, Gratianne Rabiller, Shunsuke Omodaka, Teiji Tominaga, Azadeh Yazdan-Shahmorad, Jialing Li. Pathological changes of brain oscillations following ischemic stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 2022-06-27. PMID:35754347. |
we reviewed evidence of stroke-induced changes in hippocampal oscillations and disruption of communication between brain networks as potential mechanisms underlying post-stroke cognitive dysfunction. |
2022-06-27 |
2023-08-14 |
Not clear |
| Jialei Zhang, Xiaoling Zhang, Yongyan Yang, Jun Zhao, Wenqing Hu, Yonghao Y. Effect of Different Vitamin D Levels on Cognitive Function in Aged Mice After Sevoflurane Anesthesia. Frontiers in aging neuroscience. vol 14. 2022-06-27. PMID:35754958. |
these data show that, low levels of vd aggravated the delayed emergence and cognitive dysfunction in aged mice caused by sevoflurane anesthesia, while higher levels of vd mitigated this impairment by enhancing cholinergic activity and reducing inflammatory factor expression in the hippocampus. |
2022-06-27 |
2023-08-14 |
mouse |
| Chenglong Li, Qi Li, Shuai Liu, Jiaying Li, Wei Yu, Yan Li, Ruirui Zhang, Sihua Q. sVCAM1 in the Hippocampus Contributes to Postoperative Cognitive Dysfunction in Mice by Inducing Microglial Activation Through the VLA-4 Receptor. Molecular neurobiology. 2022-06-21. PMID:35727436. |
svcam1 in the hippocampus contributes to postoperative cognitive dysfunction in mice by inducing microglial activation through the vla-4 receptor. |
2022-06-21 |
2023-08-14 |
mouse |
| Chenglong Li, Qi Li, Shuai Liu, Jiaying Li, Wei Yu, Yan Li, Ruirui Zhang, Sihua Q. sVCAM1 in the Hippocampus Contributes to Postoperative Cognitive Dysfunction in Mice by Inducing Microglial Activation Through the VLA-4 Receptor. Molecular neurobiology. 2022-06-21. PMID:35727436. |
in conclusion, increased svcam1 in the hippocampus is involved in microglial activation and cognitive dysfunction induced by surgery. |
2022-06-21 |
2023-08-14 |
mouse |
| Shizhan Ma, Wenkai Bi, Xueying Liu, Shangbin Li, Yaxin Qiu, Chengcheng Huang, Renjun Lv, Qingqing Yi. Single-Cell Sequencing Analysis of the db/db Mouse Hippocampus Reveals Cell-Type-Specific Insights Into the Pathobiology of Diabetes-Associated Cognitive Dysfunction. Frontiers in endocrinology. vol 13. 2022-06-20. PMID:35721719. |
single-cell sequencing analysis of the db/db mouse hippocampus reveals cell-type-specific insights into the pathobiology of diabetes-associated cognitive dysfunction. |
2022-06-20 |
2023-08-14 |
mouse |
| Zhiguo Wu, Jian Tan, Lichang Lin, Wenting Zhang, Wanqiu Yua. microRNA-140-3p protects hippocampal neuron against pyroptosis to attenuate sevoflurane inhalation-induced post-operative cognitive dysfunction in rats via activation of HTR2A/ERK/Nrf2 axis by targeting DNMT1. Cell death discovery. vol 8. issue 1. 2022-06-16. PMID:35710537. |
microrna-140-3p protects hippocampal neuron against pyroptosis to attenuate sevoflurane inhalation-induced post-operative cognitive dysfunction in rats via activation of htr2a/erk/nrf2 axis by targeting dnmt1. |
2022-06-16 |
2023-08-14 |
rat |
| Francisca Barake, Marcela Bravo-Zehnder, Alfonso Gonzále. Progress in the mechanism of neuronal surface P antigen modulating hippocampal function and implications for autoimmune brain disease. Current opinion in neurology. vol 35. issue 3. 2022-06-08. PMID:35674087. |
the aim of this study was to present a new regulation system in the hippocampus constituted by the neuronal surface p antigen (nspa) and the tyrosine phosphatase ptpmeg/ptpn4, which provides mechanistic and therapeutic possibilities for cognitive dysfunction driven by antiribosomal p protein autoantibodies in patients with systemic lupus erythematosus (sle). |
2022-06-08 |
2023-08-14 |
Not clear |
| Jin Wang, Qian Zhu, Yun Wang, Jun Peng, Liang Shao, Xinyi L. Irisin protects against sepsis-associated encephalopathy by suppressing ferroptosis via activation of the Nrf2/GPX4 signal axis. Free radical biology & medicine. 2022-06-06. PMID:35660523. |
this study is designed to verify the existence of ferroptosis in the pathogenesis of sae and demonstrate that irisin attenuated cognitive dysfunction in sae mice via inhibition of hippocampus ferroptosis. |
2022-06-06 |
2023-08-14 |
mouse |
| Mohamed Z Habib, Mariane G Tadros, Hadwa A Abd-Alkhalek, Magda I Mohamad, Dalia M Eid, Fatma E Hassan, Hend Elhelaly, Yasser El Faramawy, Sawsan Aboul-Fotou. Harmine prevents 3-nitropropionic acid-induced neurotoxicity in rats via enhancing NRF2-mediated signaling: Involvement of p21 and AMPK. European journal of pharmacology. 2022-05-27. PMID:35623405. |
this study draws attention to the protective role of harmine against 3-np-induced motor and cognitive dysfunction that could be mediated via enhancing nrf2-mediated signaling with subsequent amelioration of oxidative stress injury via nrf2 activators, p21 and ampk, in the striatum, prefrontal cortex, and hippocampus which could offer a promising therapeutic tool to slow the progression of hd. |
2022-05-27 |
2023-08-13 |
rat |
| Xuhong Fan, Zhenyu Zhao, Zixia Huang, Mingyue Wu, Deming Wang, Ji Xia. Mineralocorticoid receptor agonist aldosterone rescues hippocampal neural stem cell proliferation defects and improves postoperative cognitive function in aged mice. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. 2022-05-26. PMID:35615969. |
taken together, our results suggested the potential therapeutic importance of targeting mr for increasing hippocampal neural stem cell proliferation and for treating postoperative cognitive dysfunction (pocd). |
2022-05-26 |
2023-08-13 |
mouse |
| Zahra Esmaili, Maryam Naseh, Fatemeh Karimi, Maryam Moosav. A stereological study reveals nanoscale-alumina induces cognitive dysfunction in mice related to hippocampal structural changes. Neurotoxicology. 2022-05-23. PMID:35605684. |
a stereological study reveals nanoscale-alumina induces cognitive dysfunction in mice related to hippocampal structural changes. |
2022-05-23 |
2023-08-13 |
mouse |
| Xvlei Hu, Liang Wu, Yujun Wen, Juan Liu, Hailiang Li, Yifan Zhang, Zhihua Wang, Jiangwei Ding, Zhong Zeng, Hechun Xi. Hippocampal Mitochondrial Abnormalities Induced the Dendritic Complexity Reduction and Cognitive Decline in a Rat Model of Spinal Cord Injury. Oxidative medicine and cellular longevity. vol 2022. 2022-05-16. PMID:35571236. |
in addition, a battery of behavioral tests in these animals revealed hippocampal based cognitive dysfunction, which could be attributed to changes in the dendritic complexity of hippocampal neurons. |
2022-05-16 |
2023-08-13 |
rat |
| Jiangqi Hu, Xiaoyu Wang, Wei Kong, Qingsong Jian. Tooth Loss Suppresses Hippocampal Neurogenesis and Leads to Cognitive Dysfunction in Juvenile Sprague-Dawley Rats. Frontiers in neuroscience. vol 16. 2022-05-16. PMID:35573291. |
tooth loss suppresses hippocampal neurogenesis and leads to cognitive dysfunction in juvenile sprague-dawley rats. |
2022-05-16 |
2023-08-13 |
rat |
| Yirong Zeng, Lixuan Wang, Yijun Zhou, Mei Liang, Jiajia Yu, Sisi Wu, Yan Zho. NMDA receptor antagonists engender neuroprotection against gp120-induced cognitive dysfunction in Rats through Modulation of PKR activation, oxidative stress, ER stress and IRE1α Signal Pathway. The European journal of neuroscience. 2022-05-11. PMID:35543645. |
in conclusion, this study demonstrates that nmdars plays a key role in hiv/gp120 induced hippocampal damage and cognitive dysfunction through pkr mediated oxidative stress, er stress, and ire1α/jnk signaling pathway in rats, implicating pkr inhibitors could provide a novel neuroprotective strategy for hand via inhibiting er stress and its downstream ire1α signaling pathway. |
2022-05-11 |
2023-08-13 |
human |
| Amir Rostami, Fatemeh Taleahmad, Narges Haddadzadeh-Niri, Ensiye Joneidi, Siamak Afshin-Majd, Tourandokht Baluchnejadmojarad, Mehrdad Roghan. Sinomenine Attenuates Trimethyltin-Induced Cognitive Decline via Targeting Hippocampal Oxidative Stress and Neuroinflammation. Journal of molecular neuroscience : MN. 2022-05-11. PMID:35543800. |
this study demonstrated that sinomenine could lessen tmt-induced cognitive dysfunction which is partly due to its attenuation of hippocampal oxidative stress and neuroinflammation. |
2022-05-11 |
2023-08-13 |
Not clear |
| Jingbo Wei, Hui Liu, Ziqi Liu, Xiaohua Jiang, Weiping Wan. The Temporal and Spatial Changes of Th17, Tregs, and Related Cytokines in Epilepsy Lesions. Applied bionics and biomechanics. vol 2022. 2022-05-09. PMID:35528532. |
results showed that th17 and its related cytokines in epilepsy lesions played a role mainly at acute phase of epilepsy, and they were positively correlated with the pathological changes in the hippocampus and neurological and cognitive dysfunction caused by epilepsy. |
2022-05-09 |
2023-08-13 |
rat |
| Xuemei Liang, Rong Zhan. Effects of Minocycline on Cognitive Impairment, Hippocampal Inflammatory Response, and Hippocampal Alzheimer's Related Proteins in Aged Rats after Propofol Anesthesia. Disease markers. vol 2022. 2022-05-06. PMID:35521638. |
the aim of this study was to evaluate the effect of minocycline preadministration on cognitive dysfunction, hippocampal inflammatory response, and hippocampal senile dementia-related proteins induced by propofol anesthesia in aged rats. |
2022-05-06 |
2023-08-13 |
rat |
| Thomas A Kim, Michelle D Syty, Kaitlyn Wu, Shaoyu G. Adult hippocampal neurogenesis and its impairment in Alzheimer's disease. Zoological research. vol 43. issue 3. 2022-05-03. PMID:35503338. |
cognitive dysfunction is a common symptom of ad patients and progressive memory loss has been attributed to the degeneration of the hippocampus. |
2022-05-03 |
2023-08-13 |
Not clear |
| Yahang Lin, Min He, Xiaoyun Zeng, Xia Sheng, Siyi Wang, Fengzhen Cu. 4-hydroxybenzophenone exposure inhibits mouse hippocampal neural stem cell proliferation in vitro by upregulating Cxcl1. Toxicology in vitro : an international journal published in association with BIBRA. 2022-04-27. PMID:35476924. |
our recent mechanistic study in mice showed that early life exposure to a major benzophenone metabolite, 4-hydroxybenzophenone (4hbp), disrupted endoplasmic reticulum (er) proteostasis and evoked inflammatory response in hippocampal neural stem cells (nscs), leading to cognitive dysfunction. |
2022-04-27 |
2023-08-13 |
mouse |
| Hajime Miyanishi, Ayumu Kitazawa, Naotaka Izuo, Shin-Ichi Muramatsu, Atsumi Nitt. N-Acetyl Transferase, Shati/Nat8l, in the Dorsal Hippocampus Suppresses Aging-induced Impairment of Cognitive Function in Mice. Neurochemical research. 2022-04-16. PMID:35428956. |
moreover, the cognitive dysfunction observed in aged mice was reversed by shati/nat8l overexpression in the dorsal hippocampus. |
2022-04-16 |
2023-08-13 |
mouse |