| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Meiwen Guo, Shuang Chen, Jitong Lao, Jiantang Liang, Hao Chen, Jingyi Tong, Yonghao Huang, Dandan Jia, Qifu L. 3BDO Alleviates Seizures and Improves Cognitive Function by Regulating Autophagy in Pentylenetetrazol (PTZ)-Kindled Epileptic Mice Model. Neurochemical research. 2022-10-15. PMID:36243819. |
in addition, the autophagy activator en6 reversed the decrease in the 3bdo-induced autophagy and aggravated the seizures and cognitive dysfunction in the epileptic mice. 3bdo regulates autophagy by activating the mtor signaling pathway in ptz-kindled epileptic mice model, thereby alleviating hippocampus neuronal loss and astrocytes proliferation, reducing seizures and effectively improving cognitive function. |
2022-10-15 |
2023-08-14 |
mouse |
| Clara Berdasco, Alipio Pinto, Mariano G Blake, Fernando Correa, Nadia A Longo Carbajosa, Ana B Celi, Patricia A Geoghegan, Adriana Cangelosi, Myriam Nuñez, Mariela M Gironacci, Jorge Goldstei. Cognitive Deficits Found in a Pro-inflammatory State are Independent of ERK1/2 Signaling in the Murine Brain Hippocampus Treated with Shiga Toxin 2 from Enterohemorrhagic Escherichia coli. Cellular and molecular neurobiology. 2022-10-13. PMID:36227397. |
many reports have described cognitive dysfunctions in hus patients, the hippocampus being one of the brain areas targeted by ehec infection. |
2022-10-13 |
2023-08-14 |
Not clear |
| Chen Hong, Zhi Wang, Si-Li Zheng, Wen-Jun Hu, Shu-Na Wang, Yan Zhao, Chao-Yu Mia. Metrnl regulates cognitive dysfunction and hippocampal BDNF levels in D-galactose-induced aging mice. Acta pharmacologica Sinica. 2022-10-13. PMID:36229598. |
metrnl regulates cognitive dysfunction and hippocampal bdnf levels in d-galactose-induced aging mice. |
2022-10-13 |
2023-08-14 |
mouse |
| Zijian Ma, Yang Ma, Xuefeng Cao, Yunpeng Zhang, Tieying Son. Avenanthramide-C Activates Nrf2/ARE Pathway and Inhibiting Ferroptosis Pathway to Improve Cognitive Dysfunction in Aging Rats. Neurochemical research. 2022-10-12. PMID:36222956. |
in addition, avc not only improved cognitive dysfunction, but also significantly inhibited apoptosis, neuroinflammatory response, ferroptosis and oxidative stress level in the hippocampus of aging rats induced by repeated anesthesia. |
2022-10-12 |
2023-08-14 |
rat |
| Yiqiao Wang, Gaolin Qiu, Yuanhai L. The effects of hepatic ischemia/reperfusion injury on postoperative cognitive function in aged rats. Archives of medical science : AMS. vol 18. issue 5. 2022-09-26. PMID:36160337. |
the aim of this study was to investigate the effect of hepatic i/r injury on the hippocampus in rats with postoperative cognitive dysfunction (pocd). |
2022-09-26 |
2023-08-14 |
rat |
| Binbin Zhu, Yanling Zhou, Weijian Zhou, Chunqu Chen, Jianhua Wang, Shujun Xu, Qinwen Wan. Electroacupuncture modulates gut microbiota in mice: A potential target in postoperative cognitive dysfunction. Anatomical record (Hoboken, N.J. : 2007). 2022-09-12. PMID:36094150. |
our findings implied that ea decreases hippocampal inflammation of app/ps1 by upregulating benificial gut microbiota, reducing bbb and intestinal barrier dysfunction, thus alleviates postoperative cognitive dysfunction. |
2022-09-12 |
2023-08-14 |
mouse |
| Avishek Roy, Sakshi Sharma, Tapas Chandra Nag, Jatinder Katyal, Yogendra Kumar Gupta, Suman Jai. Cognitive Dysfunction and Anxiety Resulting from Synaptic Downscaling, Hippocampal Atrophy, and Ventricular Enlargement with Intracerebroventricular Streptozotocin Injection in Male Wistar Rats. Neurotoxicity research. 2022-09-07. PMID:36069980. |
cognitive dysfunction and anxiety resulting from synaptic downscaling, hippocampal atrophy, and ventricular enlargement with intracerebroventricular streptozotocin injection in male wistar rats. |
2022-09-07 |
2023-08-14 |
rat |
| M G Ratushnyak, Yu P Semochkina, E V Yastremsky, R A Kamyshinsk. Stem Cell Exosomes Improve Survival of Neural Stem Cells after Radiation Exposure. Bulletin of experimental biology and medicine. 2022-09-05. PMID:36063301. |
the death of neural stem cells in the hippocampus during radiation therapy of brain tumors leads to neurogenesis impairment and the development of cognitive dysfunctions at delayed terms after irradiation. |
2022-09-05 |
2023-08-14 |
mouse |
| Enis Hidisoglu, Deniz Kantar, Semir Ozdemir, Piraye Yargicogl. Cognitive dysfunctions and spontaneous EEG alterations induced by hippocampal amyloid pathology in rats. Advances in medical sciences. vol 67. issue 2. 2022-09-04. PMID:36058175. |
cognitive dysfunctions and spontaneous eeg alterations induced by hippocampal amyloid pathology in rats. |
2022-09-04 |
2023-08-14 |
rat |
| Yujun Tu, Qi Chen, Wenjia Guo, Pu Xiang, Haifeng Huang, Huizhi Fei, Lin Chen, Yang Yang, Zhe Peng, Chao Gu, Xiaodan Tan, Xia Liu, Yi Lu, Rongchun Chen, Hong Wang, Ying Luo, Junqing Yan. MiR-702-5p ameliorates diabetic encephalopathy in db/db mice by regulating 12/15-LOX. Experimental neurology. 2022-08-27. PMID:36029808. |
in vivo, diabetic mice with cognitive dysfunction and hippocampal neuronal damage had a concomitant increase in amyloid precursor protein (app), amyloid beta(aβ), tau, bax protein expressions; by contrast, bcl-2 protein expression was significantly decreased. |
2022-08-27 |
2023-08-14 |
mouse |
| Fan Liu, Jianru Sun, Xue Wang, Sixuan Jin, Fengrun Sun, Tao Wang, Bo Yuan, Wenying Qiu, Chao M. Focal-type, but not Diffuse-type, Amyloid Beta Plaques are Correlated with Alzheimer's Neuropathology, Cognitive Dysfunction, and Neuroinflammation in the Human Hippocampus. Neuroscience bulletin. 2022-08-26. PMID:36028642. |
focal-type, but not diffuse-type, amyloid beta plaques are correlated with alzheimer's neuropathology, cognitive dysfunction, and neuroinflammation in the human hippocampus. |
2022-08-26 |
2023-08-14 |
human |
| Jin Zhang, Yu Zhang, Yan Liu, Xiaoyuan Ni. Naringenin Attenuates Cognitive Impairment in a Rat Model of Vascular Dementia by Inhibiting Hippocampal Oxidative Stress and Inflammatory Response and Promoting N-Methyl-D-Aspartate Receptor Signaling Pathway. Neurochemical research. 2022-08-26. PMID:36028734. |
herein, the purpose of present study was to elucidate whether naringenin attenuates cognitive dysfunction in vad via inhibiting hippocampal oxidative stress and inflammatory response, and promoting n-methyl-d-aspartate receptors (nmdars) signaling pathway. |
2022-08-26 |
2023-08-14 |
rat |
| Eru Mb. Hippocampal Astrogliotic Reduction in Scopolamine Hydrobromide-Induced Alzheimer's Type Cognitive Dysfunction Wistar Rats Following Administration of Aqueous Extract of Telfairia Occidentalis (pumpkin) seeds. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 36. issue 2. 2022-08-10. PMID:35947741. |
hippocampal astrogliotic reduction in scopolamine hydrobromide-induced alzheimer's type cognitive dysfunction wistar rats following administration of aqueous extract of telfairia occidentalis (pumpkin) seeds. |
2022-08-10 |
2023-08-14 |
human |
| Eru Mb. Hippocampal Astrogliotic Reduction in Scopolamine Hydrobromide-Induced Alzheimer's Type Cognitive Dysfunction Wistar Rats Following Administration of Aqueous Extract of Telfairia Occidentalis (pumpkin) seeds. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. vol 36. issue 2. 2022-08-10. PMID:35947741. |
in this study, the effect of aqueous extract of telfairia occidentalis seeds on hippocampal astrogliosis was probed using scopolamine-induced alzheimer's type cognitive dysfunction wistar rats. |
2022-08-10 |
2023-08-14 |
human |
| Xiaona Liu, Jing Wan. NMDA receptors mediate synaptic plasticity impairment of hippocampal neurons due to arsenic exposure. Neuroscience. 2022-07-29. PMID:35905926. |
chronic arsenic exposure results in cognitive dysfunction due to arsenic and its metabolites accumulating in hippocampus. |
2022-07-29 |
2023-08-14 |
Not clear |
| Wentao Dong, Xia Li, Xiaokang Wang, Xiang Cheng, Lingde Kong, Zhiyong Guo, Hao Jin. Influence of Dexmedetomidine on Cognitive Function and Inflammatory Factors in Rats and Analysis of Its Molecular Mechanism after Cardiac Surgery under Cardiopulmonary Bypass. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 2. 2022-07-23. PMID:35869718. |
then dex can improve the cognitive dysfunction of rats undergoing cardiac surgery under cpb, and its molecular mechanism may be to reduce the inflammation around the heart and hippocampus. |
2022-07-23 |
2023-08-14 |
rat |
| Ming Hou, Qiongyu Zhang, Kai Den. Study on the Effect of Dexmedetomidine on Postoperative Cognitive Dysfunction and Inflammation in Aged Rats. Contrast media & molecular imaging. vol 2022. 2022-07-22. PMID:35866065. |
the aim of this study is to investigate the effect of dexmedetomidine on cognitive dysfunction and inflammatory cytokines in the hippocampus after surgery in aged rats. |
2022-07-22 |
2023-08-14 |
rat |
| Ting Luo, Ya-Nan Hao, Dan-Dan Lin, Xiao Huang, An-Shi W. Ginkgolide B improved postoperative cognitive dysfunction by inhibiting microgliosis-mediated neuroinflammation in the hippocampus of mice. BMC anesthesiology. vol 22. issue 1. 2022-07-19. PMID:35850641. |
ginkgolide b improved postoperative cognitive dysfunction by inhibiting microgliosis-mediated neuroinflammation in the hippocampus of mice. |
2022-07-19 |
2023-08-14 |
mouse |
| Li Yang, Jing-Ru Hao, Yin Gao, Xiu Yang, Xiao-Ran Shen, Hu-Yi Wang, Nan Sun, Can Ga. HDAC3 of dorsal hippocampus induces postoperative cognitive dysfunction in aged mice. Behavioural brain research. 2022-07-10. PMID:35810999. |
hdac3 of dorsal hippocampus induces postoperative cognitive dysfunction in aged mice. |
2022-07-10 |
2023-08-14 |
mouse |
| Yohei Hokama, Masahiko Nishimura, Ryoichi Usugi, Kyoko Fujiwara, Chiaki Katagiri, Hiroshi Takagi, Shogo Ishiuch. Recovery from the damage of cranial radiation modulated by memantine, an NMDA receptor antagonist combined with hyperbaric oxygen therapy. Neuro-oncology. 2022-06-28. PMID:35762568. |
however, cranial radiation induces hippocampal dysfunction and white matter injury; this leads to cognitive dysfunction, and results in a reduced quality of life in patients. |
2022-06-28 |
2023-08-14 |
Not clear |