| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Rubio-Morell, R Martín-González, O Herreros-Rodríguez, P González-Pérez, S Hernández-Exposito, I Quintero-Fuentes, R Gracia-Marc. [Neuropsychological assessment of the effectiveness of OROS-methylphenidate in attention deficit hyperactivity disorder]. Revista de neurologia. vol 46. issue 10. 2008-09-15. PMID:18465700. |
there is wide evidence about dopaminergic and noradrenergic mechanisms in fronto-striatal circuits which are thought to be related with attention deficit hyperactivity disorder (adhd) neurobiology. |
2008-09-15 |
2023-08-12 |
Not clear |
| Jan Frölich, Manfred Döpfne. [The treatment of Attention-Deficit/Hyperactivity Disorders with polyunsaturated fatty acids - an effective treatment alternative?]. Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie. vol 36. issue 2. 2008-08-29. PMID:18622940. |
increasing evidence indicates that lc-pufa imbalance or deficiencies may be associated with attention deficit/hyperactivity disorder (adhd) through involvement in the dopaminergic corico-striatal metabolism. |
2008-08-29 |
2023-08-12 |
human |
| Andrea G Ludolph, Jan Kassubek, Klaus Schmeck, Cornelia Glaser, Arthur Wunderlich, Andreas K Buck, Sven N Reske, Joerg M Fegert, Felix M Mottagh. Dopaminergic dysfunction in attention deficit hyperactivity disorder (ADHD), differences between pharmacologically treated and never treated young adults: a 3,4-dihdroxy-6-[18F]fluorophenyl-l-alanine PET study. NeuroImage. vol 41. issue 3. 2008-08-14. PMID:18424180. |
dopaminergic dysfunction in attention deficit hyperactivity disorder (adhd), differences between pharmacologically treated and never treated young adults: a 3,4-dihdroxy-6-[18f]fluorophenyl-l-alanine pet study. |
2008-08-14 |
2023-08-12 |
human |
| Andrea G Ludolph, Jan Kassubek, Klaus Schmeck, Cornelia Glaser, Arthur Wunderlich, Andreas K Buck, Sven N Reske, Joerg M Fegert, Felix M Mottagh. Dopaminergic dysfunction in attention deficit hyperactivity disorder (ADHD), differences between pharmacologically treated and never treated young adults: a 3,4-dihdroxy-6-[18F]fluorophenyl-l-alanine PET study. NeuroImage. vol 41. issue 3. 2008-08-14. PMID:18424180. |
the dopaminergic system plays a key role in attention-deficit/hyperactivity disorder (adhd). |
2008-08-14 |
2023-08-12 |
human |
| D Lule, A C Ludolph, A G Ludolp. Neurodevelopmental and neurodegenerative diseases - is there a pathophysiological link? Attention-deficit/hyperactivity disorder and amyotrophic lateral sclerosis as examples. Medical hypotheses. vol 70. issue 6. 2008-08-13. PMID:18158219. |
at the neurobiological level, there is evidence for hyperactivity in the glutamatergic system and a - potentially related - dopaminergic hypoactivity in adhd and als. |
2008-08-13 |
2023-08-12 |
Not clear |
| Li-Li Liu, Bao-Min Li, Jie Yang, Yu-Wei Wan. Does dopaminergic reward system contribute to explaining comorbidity obesity and ADHD? Medical hypotheses. vol 70. issue 6. 2008-08-13. PMID:18158220. |
does dopaminergic reward system contribute to explaining comorbidity obesity and adhd? |
2008-08-13 |
2023-08-12 |
Not clear |
| Li-Li Liu, Bao-Min Li, Jie Yang, Yu-Wei Wan. Does dopaminergic reward system contribute to explaining comorbidity obesity and ADHD? Medical hypotheses. vol 70. issue 6. 2008-08-13. PMID:18158220. |
given the above background, we hypothesize that the increased prevalence of adhd in obese individual could be explained by the imbalance of dopaminergic reward system. |
2008-08-13 |
2023-08-12 |
Not clear |
| D J Heal, S L Smith, R S Kulkarni, H L Rowle. New perspectives from microdialysis studies in freely-moving, spontaneously hypertensive rats on the pharmacology of drugs for the treatment of ADHD. Pharmacology, biochemistry, and behavior. vol 90. issue 2. 2008-08-12. PMID:18456311. |
when the findings are compared with the clinical efficacy of drugs used in treating adhd, they indicate that the most efficacious drugs powerfully increase both norepinephrinergic and dopaminergic neurotransmission. |
2008-08-12 |
2023-08-12 |
rat |
| Kerstin Malmberg, Hanna-Linn Wargelius, Paul Lichtenstein, Lars Oreland, Jan-Olov Larsso. ADHD and Disruptive Behavior scores - associations with MAO-A and 5-HTT genes and with platelet MAO-B activity in adolescents. BMC psychiatry. vol 8. 2008-08-06. PMID:18430257. |
pharmacological and genetic studies suggest the importance of the dopaminergic, serotonergic, and noradrenergic systems in the pathogenesis of attention deficit hyperactivity disorder (adhd) and disruptive behavior disorder (dbd). |
2008-08-06 |
2023-08-12 |
Not clear |
| Li-Li Liu, Jie Yang, Ge-Fei Lei, Gui-Ju Wang, Yu-Wei Wang, Ruo-Peng Su. Atomoxetine increases histamine release and improves learning deficits in an animal model of attention-deficit hyperactivity disorder: the spontaneously hypertensive rat. Basic & clinical pharmacology & toxicology. vol 102. issue 6. 2008-06-12. PMID:18346050. |
substantial development in the pharmacological treatment for attention-deficit hyperactivity disorder (adhd) has been made recently including approval of new non-stimulant agents targeting noradrenergic, histaminergic and dopaminergic systems. |
2008-06-12 |
2023-08-12 |
rat |
| Daniele Q M Madureira, Luis Alfredo V de Carvalho, Elie Cheniau. [A neurocomputational model for the thalamocortical loop: towards a better understanding of attention deficit hyperactivity disorder]. Arquivos de neuro-psiquiatria. vol 65. issue 4A. 2008-06-02. PMID:18094875. |
inattention symptoms observed in patients with attention deficit hyperactivity disorder (adhd) are mostly related to a hypoactivity in the mesocortical dopaminergic pathway. |
2008-06-02 |
2023-08-12 |
Not clear |
| Daniele Q M Madureira, Luis Alfredo V de Carvalho, Elie Cheniau. [A neurocomputational model for the thalamocortical loop: towards a better understanding of attention deficit hyperactivity disorder]. Arquivos de neuro-psiquiatria. vol 65. issue 4A. 2008-06-02. PMID:18094875. |
however, mesothalamic dopaminergic variations also affect the attentional control, and possibly lead to attention alterations in adhd. |
2008-06-02 |
2023-08-12 |
Not clear |
| R M Kostrzewa, J P Kostrzewa, R A Kostrzewa, P Nowak, R Bru. Pharmacological models of ADHD. Journal of neural transmission (Vienna, Austria : 1996). vol 115. issue 2. 2008-05-30. PMID:17994186. |
neonatal 6-ohda-induced dopaminergic denervation of rodent forebrain also produces hyperactivity - and this model, or variations of it, remain the most widely-used animal model of adhd. |
2008-05-30 |
2023-08-12 |
Not clear |
| Alessio Squassina, Matthew Lanktree, Vincenzo De Luca, Umesh Jain, Marilee Krinsky, James L Kennedy, Pierandrea Mugli. Investigation of the dopamine D5 receptor gene (DRD5) in adult attention deficit hyperactivity disorder. Neuroscience letters. vol 432. issue 1. 2008-04-24. PMID:18164132. |
several lines of evidence from neuroimaging, pharmacology and genetics support the involvement of the dopaminergic system in the etiology of attention deficit hyperactivity disorder (adhd). |
2008-04-24 |
2023-08-12 |
Not clear |
| Stefanie Zehle, Joerg Bock, Grzegorz Jezierski, Michael Gruss, Katharina Brau. Methylphenidate treatment recovers stress-induced elevated dendritic spine densities in the rodent dorsal anterior cingulate cortex. Developmental neurobiology. vol 67. issue 14. 2008-03-27. PMID:17874461. |
adhd is typically treated with methylphenidate (mp), a drug acting on the dopaminergic system. |
2008-03-27 |
2023-08-12 |
Not clear |
| Richard D Todd, Rosalind J Neuma. Gene-environment interactions in the development of combined type ADHD: evidence for a synapse-based model. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 8. 2008-02-05. PMID:17955458. |
given the known functions and the known areas of expression of these three genes at the dopaminergic synapse in the pre-frontal cortex, the results are compatible with a synapse-based model of the development of this form of adhd. |
2008-02-05 |
2023-08-12 |
Not clear |
| San-Duo Jiang, Xiao-Dong Wu, Ye Zhang, Guo-Mei Tang, Yi-Ping Qian, Dong-Xiang Wan. No association between attention-deficit hyperactivity disorder and catechol-O-methyltransferase gene in Chinese. Yi chuan xue bao = Acta genetica Sinica. vol 32. issue 8. 2008-01-31. PMID:16231731. |
since catechel-o-methyltransferase (comt) is an enzyme involved in the degradation of catecholaminergic neurotransmitters of the dopaminergic and noradrenergic systems,it is possible that comt may play a role in adhd. |
2008-01-31 |
2023-08-12 |
Not clear |
| E Perlov, A Philipsen, B Hesslinger, M Buechert, J Ahrendts, B Feige, E Bubl, J Hennig, D Ebert, L Tebartz van Els. Reduced cingulate glutamate/glutamine-to-creatine ratios in adult patients with attention deficit/hyperactivity disorder -- a magnet resonance spectroscopy study. Journal of psychiatric research. vol 41. issue 11. 2007-11-30. PMID:17303167. |
the dopaminergic system is thought to be essentially involved in the pathogenesis of attention deficit/hyperactivity disorder (adhd). |
2007-11-30 |
2023-08-12 |
Not clear |
| E Perlov, A Philipsen, B Hesslinger, M Buechert, J Ahrendts, B Feige, E Bubl, J Hennig, D Ebert, L Tebartz van Els. Reduced cingulate glutamate/glutamine-to-creatine ratios in adult patients with attention deficit/hyperactivity disorder -- a magnet resonance spectroscopy study. Journal of psychiatric research. vol 41. issue 11. 2007-11-30. PMID:17303167. |
in the present study, we wanted to test the hypothesis that prefrontal glutamate signals indirectly indicate dopaminergic dysfunction in adult patients with adhd. |
2007-11-30 |
2023-08-12 |
Not clear |
| Manali Das, Kanchan Mukhopadhya. DAT1 3'-UTR 9R allele: preferential transmission in Indian children with attention deficit hyperactivity disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 144B. issue 6. 2007-11-07. PMID:17440935. |
genetic alterations in the dopaminergic system are frequently observed in association with attention deficit hyperactivity disorder (adhd) and a 40 bp variable number of tandem repeats (vntr) in the 3'-untranslated region (3'-utr) of the dopamine transporter gene (dat1) has been investigated in different populations. |
2007-11-07 |
2023-08-12 |
Not clear |