| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Veronika Engert, Jens C Pruessne. Dopaminergic and noradrenergic contributions to functionality in ADHD: the role of methylphenidate. Current neuropharmacology. vol 6. issue 4. 2010-06-11. PMID:19587853. |
dopaminergic and noradrenergic contributions to functionality in adhd: the role of methylphenidate. |
2010-06-11 |
2023-08-12 |
Not clear |
| Veronika Engert, Jens C Pruessne. Dopaminergic and noradrenergic contributions to functionality in ADHD: the role of methylphenidate. Current neuropharmacology. vol 6. issue 4. 2010-06-11. PMID:19587853. |
methylphenidate (mph), a psychostimulant affecting both the dopaminergic and the noradrenergic systems, is one of the most frequently prescribed treatments for adhd. |
2010-06-11 |
2023-08-12 |
Not clear |
| Javier Quintero, M Navas, A Fernández, T Orti. Advances in attention deficit hyperactivity disorder.What does neuroimaging provide us with? Actas espanolas de psiquiatria. vol 37. issue 6. 2010-05-20. PMID:20066587. |
structural and functional imaging studies suggest that the adhd pathophysiology would be conditioned by a dysfunction in the fronto-subcortical pathways, as well as imbalances in the dopaminergic and noradrenergic systems. |
2010-05-20 |
2023-08-12 |
Not clear |
| Fleur L Warton, Fleur M Howells, Vivienne A Russel. Increased glutamate-stimulated release of dopamine in substantia nigra of a rat model for attention-deficit/hyperactivity disorder--lack of effect of methylphenidate. Metabolic brain disease. vol 24. issue 4. 2010-04-29. PMID:19821016. |
attention-deficit/hyperactivity disorder (adhd) is a behavioural disorder that has been associated with dysfunction of the dopaminergic system. |
2010-04-29 |
2023-08-12 |
rat |
| C G Baehne, A-C Ehlis, M M Plichta, A Conzelmann, P Pauli, C Jacob, L Gutknecht, K-P Lesch, A J Fallgatte. Tph2 gene variants modulate response control processes in adult ADHD patients and healthy individuals. Molecular psychiatry. vol 14. issue 11. 2010-01-25. PMID:18427560. |
although therapeutic interventions in attention-deficit/hyperactivity disorder (adhd) still focus on the dopaminergic system, recent studies indicate a serotonergic dysfunction in this disease as well. |
2010-01-25 |
2023-08-12 |
Not clear |
| Courtney A Ficks, Irwin D Waldma. Gene-environment interactions in attention-deficit/hyperactivity disorder. Current psychiatry reports. vol 11. issue 5. 2010-01-04. PMID:19785980. |
genetic associations with adhd have been found in the dopaminergic, serotonergic, and noradrenergic neurotransmitter systems, but findings are inconsistent across studies. |
2010-01-04 |
2023-08-12 |
Not clear |
| Andrea T Schaefers, Gertraud Teuchert-Noodt, Francesco Bagorda, Susanne Brummelt. Effect of postnatal methamphetamine trauma and adolescent methylphenidate treatment on adult hippocampal neurogenesis in gerbils. European journal of pharmacology. vol 616. issue 1-3. 2009-10-19. PMID:19540225. |
animals were first treated with either a single methamphetamine challenge on postnatal day 14 (to cause a disturbance in the dopaminergic system, to mimic the disturbed dopaminergic system seen in adhd children) or saline and then received a daily oral application of 5 mg/kg methylphenidate or water from postnatal day 30-60 or were left undisturbed. |
2009-10-19 |
2023-08-12 |
Not clear |
| Doug Hyun Han, Young Sik Lee, Churl Na, Jee Young Ahn, Un Sun Chung, Melissa A Daniels, Charlotte A Haws, Perry F Rensha. The effect of methylphenidate on Internet video game play in children with attention-deficit/hyperactivity disorder. Comprehensive psychiatry. vol 50. issue 3. 2009-08-14. PMID:19374970. |
a number of studies about attention-deficit/hyperactivity disorder (adhd) and internet video game play have examined the prefrontal cortex and dopaminergic system. |
2009-08-14 |
2023-08-12 |
human |
| Julie A Dopheide, Steven R Pliszk. Attention-deficit-hyperactivity disorder: an update. Pharmacotherapy. vol 29. issue 6. 2009-08-06. PMID:19476419. |
in patients with adhd, neurobiologic research has shown a lack of connectivity in key brain regions, inhibitory control deficits, delayed brain maturation, and noradrenergic and dopaminergic dysfunction in multiple brain regions. |
2009-08-06 |
2023-08-12 |
Not clear |
| Swen Hesse, Olaf Ballaschke, Henryk Barthel, Osama Sabr. Dopamine transporter imaging in adult patients with attention-deficit/hyperactivity disorder. Psychiatry research. vol 171. issue 2. 2009-05-11. PMID:19176281. |
the aim of this study was to provide in vivo evidence for the hypothesis that dopaminergic neurotransmission is altered in adult patients with attention-deficit/hyperactivity disorder (adhd). |
2009-05-11 |
2023-08-12 |
Not clear |
| Swen Hesse, Olaf Ballaschke, Henryk Barthel, Osama Sabr. Dopamine transporter imaging in adult patients with attention-deficit/hyperactivity disorder. Psychiatry research. vol 171. issue 2. 2009-05-11. PMID:19176281. |
these data indicate a reduced dopaminergic but not serotonergic transmitter reuptake function in adult adhd. |
2009-05-11 |
2023-08-12 |
Not clear |
| San-Duo Jiang, Mei He, Yi-Ping Qian, Dong-Xian Wang, Ye Zhang, Fei Li, Hong-Jun Tian, Ren-E Xin, Guo-Mei Tang, Xiao-Dong W. [Genome-wide search for linkage to attention deficit hyperactivity disorder (ADHD) on the X chromosome]. Yi chuan = Hereditas. vol 28. issue 1. 2009-04-16. PMID:16469712. |
molecular genetic and pharmacological studies suggest the involvement of dopaminergic and noradrenergic neurotransmitter systems in adhd, e.g , several reports have found association between adhd and the dopamine receptor gene drd-4.the dopamine transporter gene dat1, and the catechol-o-methyltransferase. |
2009-04-16 |
2023-08-12 |
Not clear |
| Francois Gono. The dopaminergic hypothesis of attention-deficit/hyperactivity disorder needs re-examining. Trends in neurosciences. vol 32. issue 1. 2009-03-24. PMID:18986716. |
this dopamine-deficit theory of adhd is often based upon an overly simplistic dopaminergic theory of reward. |
2009-03-24 |
2023-08-12 |
Not clear |
| Daniel Lenz, Kerstin Krauel, Jeanette Schadow, Lioba Baving, Emrah Duzel, Christoph S Herrman. Enhanced gamma-band activity in ADHD patients lacks correlation with memory performance found in healthy children. Brain research. vol 1235. 2009-01-28. PMID:18598680. |
furthermore, enhanced gbrs in adhd could also indicate a decrease of neuronal signal-to-noise ratio, partially caused by the genetic variations within the dopaminergic pathway of adhd patients. |
2009-01-28 |
2023-08-12 |
human |
| S Johansson, H Halleland, A Halmøy, K K Jacobsen, E T Landaas, M Dramsdahl, O B Fasmer, P Bergsholm, A J Lundervold, C Gillberg, K Hugdahl, P M Knappskog, J Haavi. Genetic analyses of dopamine related genes in adult ADHD patients suggest an association with the DRD5-microsatellite repeat, but not with DRD4 or SLC6A3 VNTRs. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 8. 2009-01-06. PMID:18081165. |
recent meta-analyses have indicated an association between genes involved in dopaminergic signaling and childhood adhd, but little is known about their possible role in adult adhd. |
2009-01-06 |
2023-08-12 |
Not clear |
| Eva Kereszturi, Zsanett Tarnok, Emese Bognar, Krisztina Lakatos, Luca Farkas, Julia Gadoros, Maria Sasvari-Szekely, Zsofia Nemod. Catechol-O-methyltransferase Val158Met polymorphism is associated with methylphenidate response in ADHD children. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 8. 2009-01-06. PMID:18214865. |
here we present a case-control study and pharmacogenetic association analyses in adhd investigating three dopaminergic polymorphisms. |
2009-01-06 |
2023-08-12 |
Not clear |
| Francis Joseph McClernon, Scott Haden Kollin. ADHD and smoking: from genes to brain to behavior. Annals of the New York Academy of Sciences. vol 1141. 2008-12-12. PMID:18991955. |
we propose that adhd and smoking involve dysregulation of dopaminergic and nicotinic-acetylcholinergic circuits and that these aberrations are likely to arise, at least in part, from genetic variations. |
2008-12-12 |
2023-08-12 |
Not clear |
| Raul R Gainetdino. Dopamine transporter mutant mice in experimental neuropharmacology. Naunyn-Schmiedeberg's archives of pharmacology. vol 377. issue 4-6. 2008-12-03. PMID:18057916. |
furthermore, dat mutant mice provided an opportunity to model in vivo conditions of extreme dopaminergic dysfunction that could be relevant for human disorders such as adhd, schizophrenia, and parkinson's disease and, thus, could serve as test systems for developing novel treatments for these and related disorders. |
2008-12-03 |
2023-08-12 |
mouse |
| R Martín-González, P A González-Pérez, M Izquierdo-Hernández, S Hernández-Expósito, M A Alonso-Rodríguez, I Quintero-Fuentes, B Rubio-Morel. [Neuropsychological assessment of memory in attention deficit hyperactivity disorder: the role of executive functions]. Revista de neurologia. vol 47. issue 5. 2008-11-18. PMID:18780266. |
there is an important agreement on the consideration of attention deficit hyperactivity disorder (adhd) as a condition characterized by neurodevelopmental dysfunction of fronto-striatal dopaminergic and noradrenergic circuits with resultant executive deficits in cognitive functioning. |
2008-11-18 |
2023-08-12 |
Not clear |
| Heleen Suzanne Soeters, Fleur Margaret Howells, Vivienne Ann Russel. Methylphenidate does not increase ethanol consumption in a rat model for attention-deficit hyperactivity disorder-the spontaneously hypertensive rat. Metabolic brain disease. vol 23. issue 3. 2008-10-31. PMID:18665438. |
attention-deficit hyperactivity disorder (adhd) is a behavioural disorder that has been suggested to result from disturbances in the dopaminergic system of the brain. |
2008-10-31 |
2023-08-12 |
rat |