| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D E Comings, R Gade-Andavolu, N Gonzalez, S Wu, D Muhleman, H Blake, G Dietz, G Saucier, J P MacMurra. Comparison of the role of dopamine, serotonin, and noradrenaline genes in ADHD, ODD and conduct disorder: multivariate regression analysis of 20 genes. Clinical genetics. vol 57. issue 3. 2000-06-28. PMID:10782925. |
these results indicate that the adrenergic genes play a greater role in adhd than either the dopaminergic or serotonergic genes combined. |
2000-06-28 |
2023-08-12 |
human |
| A S Walters, D E Mandelbaum, D S Lewin, S Kugler, S J England, M Mille. Dopaminergic therapy in children with restless legs/periodic limb movements in sleep and ADHD. Dopaminergic Therapy Study Group. Pediatric neurology. vol 22. issue 3. 2000-05-09. PMID:10734247. |
dopaminergic therapy in children with restless legs/periodic limb movements in sleep and adhd. |
2000-05-09 |
2023-08-12 |
Not clear |
| A S Walters, D E Mandelbaum, D S Lewin, S Kugler, S J England, M Mille. Dopaminergic therapy in children with restless legs/periodic limb movements in sleep and ADHD. Dopaminergic Therapy Study Group. Pediatric neurology. vol 22. issue 3. 2000-05-09. PMID:10734247. |
alternatively, adhd and rls/plms may share a common dopaminergic deficit. |
2000-05-09 |
2023-08-12 |
Not clear |
| D Vallone, R Picetti, E Borrell. Structure and function of dopamine receptors. Neuroscience and biobehavioral reviews. vol 24. issue 1. 2000-02-17. PMID:10654668. |
deregulation of the dopaminergic system has been linked with parkinson's disease, tourette's syndrome, schizophrenia, attention deficit hyperactive disorder (adhd) and generation of pituitary tumours. |
2000-02-17 |
2023-08-12 |
Not clear |
| V A Russel. The nucleus accumbens motor-limbic interface of the spontaneously hypertensive rat as studied in vitro by the superfusion slice technique. Neuroscience and biobehavioral reviews. vol 24. issue 1. 2000-02-17. PMID:10654669. |
the behavioral disturbances of attention-deficit hyperactivity disorder (adhd) have been attributed to dysfunction of the mesolimbic dopaminergic (da) projection from the ventral tegmental area of the midbrain. |
2000-02-17 |
2023-08-12 |
rat |
| D L Picchietti, D J Underwood, W A Farris, A S Walters, M M Shah, R E Dahl, L J Trubnick, M A Bertocci, M Wagner, W A Henin. Further studies on periodic limb movement disorder and restless legs syndrome in children with attention-deficit hyperactivity disorder. Movement disorders : official journal of the Movement Disorder Society. vol 14. issue 6. 2000-01-20. PMID:10584676. |
alternative explanations for the association between adhd and rls/plms are that they are genetically linked, they share a common dopaminergic deficit, or both. |
2000-01-20 |
2023-08-12 |
human |
| J Biederman, T Spence. Attention-deficit/hyperactivity disorder (ADHD) as a noradrenergic disorder. Biological psychiatry. vol 46. issue 9. 1999-12-15. PMID:10560028. |
a wealth of pharmacological data (within and without the stimulant literature) provides strong evidence for selective clinical activity in adhd for drugs with noradrenergic and dopaminergic pharmacological profiles. |
1999-12-15 |
2023-08-12 |
Not clear |
| M Cyr, C S Brow. Current drug therapy recommendations for the treatment of attention deficit hyperactivity disorder. Drugs. vol 56. issue 2. 1998-11-02. PMID:9711446. |
although the aetiology is unknown, adhd appears to have a strong genetic component and to involve dysregulation of the cns dopaminergic system. |
1998-11-02 |
2023-08-12 |
Not clear |
| M Ernst, A J Zametkin, J A Matochik, P H Jons, R M Cohe. DOPA decarboxylase activity in attention deficit hyperactivity disorder adults. A [fluorine-18]fluorodopa positron emission tomographic study. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 15. 1998-08-07. PMID:9671677. |
converging evidence implicates the dopaminergic system and the prefrontal and nigrostriatal regions in the pathophysiology of attention deficit hyperactivity disorder (adhd). |
1998-08-07 |
2023-08-12 |
Not clear |
| M Ernst, A J Zametkin, J A Matochik, P H Jons, R M Cohe. DOPA decarboxylase activity in attention deficit hyperactivity disorder adults. A [fluorine-18]fluorodopa positron emission tomographic study. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 15. 1998-08-07. PMID:9671677. |
using positron emission tomography (pet) with [fluorine-18]fluorodopa (f18-dopa), we compared the integrity of the presynaptic dopaminergic function between 17 adhd adults and 23 healthy controls. |
1998-08-07 |
2023-08-12 |
Not clear |
| M Ernst, A J Zametkin, J A Matochik, P H Jons, R M Cohe. DOPA decarboxylase activity in attention deficit hyperactivity disorder adults. A [fluorine-18]fluorodopa positron emission tomographic study. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 15. 1998-08-07. PMID:9671677. |
these findings suggest that a prefrontal dopaminergic dysfunction mediates adhd symptoms in adults and that gender influences this abnormality. |
1998-08-07 |
2023-08-12 |
Not clear |
| M Ernst, A J Zametkin, J A Matochik, P H Jons, R M Cohe. DOPA decarboxylase activity in attention deficit hyperactivity disorder adults. A [fluorine-18]fluorodopa positron emission tomographic study. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 15. 1998-08-07. PMID:9671677. |
on the basis of previous neuroimaging findings in adhd showing discrepant findings in adults and adolescents and on evidence for midbrain dopaminergic defect in adolescents, we hypothesize that the prefrontal dopaminergic abnormality in adhd adults is secondary and results from an interaction of the primary subcortical dopaminergic deficit with processes of neural maturation and neural adaptation. |
1998-08-07 |
2023-08-12 |
Not clear |
| F X Castellanos, J Elia, M J Kruesi, W L Marsh, C S Gulotta, W Z Potter, G F Ritchie, S D Hamburger, J L Rapopor. Cerebrospinal fluid homovanillic acid predicts behavioral response to stimulants in 45 boys with attention deficit/hyperactivity disorder. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 14. issue 2. 1997-06-30. PMID:8822535. |
central dopaminergic activity has been assumed to play a role in the efficacy of stimulant drugs in attention deficit/hyperactivity disorder (adhd), although supporting evidence has been scant. |
1997-06-30 |
2023-08-12 |
Not clear |
| M Ernst, L L Liebenauer, D Tebeka, P H Jons, G Eisenhofer, D L Murphy, A J Zametki. Selegiline in ADHD adults: plasma monoamines and monoamine metabolites. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 16. issue 4. 1997-06-13. PMID:9094145. |
dopaminergic indices were associated with adhd symptom severity (conners-atrs) and noradrenergic indices with cpt performance. |
1997-06-13 |
2023-08-12 |
human |
| D E Comings, S Wu, C Chiu, R H Ring, R Gade, C Ahn, J P MacMurray, G Dietz, D Muhlema. Polygenic inheritance of Tourette syndrome, stuttering, attention deficit hyperactivity, conduct, and oppositional defiant disorder: the additive and subtractive effect of the three dopaminergic genes--DRD2, D beta H, and DAT1. American journal of medical genetics. vol 67. issue 3. 1996-12-03. PMID:8725745. |
these results suggest that ts, adhd, stuttering oppositional defiant and conduct disorder, and other behaviors associated with ts, are polygenic, due in part to these three dopaminergic genes, and that the genetics of other polygenic psychiatric disorders may be deciphered using this technique. |
1996-12-03 |
2023-08-12 |
human |
| V Russell, A de Villiers, T Sagvolden, M Lamm, J Taljaar. Altered dopaminergic function in the prefrontal cortex, nucleus accumbens and caudate-putamen of an animal model of attention-deficit hyperactivity disorder--the spontaneously hypertensive rat. Brain research. vol 676. issue 2. 1995-08-24. PMID:7614004. |
the behavioural problems of adhd have been suggested to be secondary to altered reinforcement mechanisms resulting from dysfunction of the mesolimbic and mesocortical dopaminergic systems. |
1995-08-24 |
2023-08-12 |
rat |
| F Levy, G Hobbe. The action of stimulant medication in attention deficit disorder with hyperactivity: dopaminergic, noradrenergic, or both? Journal of the American Academy of Child and Adolescent Psychiatry. vol 27. issue 6. 1989-01-25. PMID:2848797. |
the action of stimulant medication in attention deficit disorder with hyperactivity: dopaminergic, noradrenergic, or both? |
1989-01-25 |
2023-08-11 |
Not clear |