| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sarah E Henderson, Amy R Johnson, Ana I Vallejo, Lev Katz, Edmund Wong, Vilma Gabba. A preliminary study of white matter in adolescent depression: relationships with illness severity, anhedonia, and irritability. Frontiers in psychiatry. vol 4. 2013-12-10. PMID:24324445. |
specifically, anhedonia was associated with disturbances in tracts related to reward processing, including the anterior limb of the internal capsule and projection fibers to the orbitofrontal cortex. |
2013-12-10 |
2023-08-12 |
Not clear |
| Tatiana V Lipina, Paul J Fletcher, Frankie H Lee, Albert H C Wong, John C Rode. Disrupted-in-schizophrenia-1 Gln31Leu polymorphism results in social anhedonia associated with monoaminergic imbalance and reduction of CREB and β-arrestin-1,2 in the nucleus accumbens in a mouse model of depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 3. 2013-10-17. PMID:23011268. |
overall, we find neurobiological changes accompanying social anhedonia in the nac of disc1-q31l mutant mice, consistent with a role for disc1 in regulating social reward as an endophenotype of depression. |
2013-10-17 |
2023-08-12 |
mouse |
| Jonathan P Roiser, Barbara J Sahakia. Hot and cold cognition in depression. CNS spectrums. vol 18. issue 3. 2013-08-08. PMID:23481353. |
additionally, an emerging literature indicates reliable reward and punishment processing abnormalities in depression, which are especially relevant for hard-to-treat symptoms such as anhedonia. |
2013-08-08 |
2023-08-12 |
Not clear |
| Hideki Oshima, Yoichi Katayam. Neuroethics of deep brain stimulation for mental disorders: brain stimulation reward in humans. Neurologia medico-chirurgica. vol 50. issue 9. 2013-07-26. PMID:20885119. |
dbs of the reward system has recently been applied to alleviate anhedonia in patients with refractory major depression. |
2013-07-26 |
2023-08-12 |
human |
| Jonathan Savitz, Colin A Hodgkinson, Chantal Martin-Soelch, Pei-Hong Shen, Joanna Szczepanik, Allison Nugent, Peter Herscovitch, Anthony A Grace, David Goldman, Wayne C Drevet. The functional DRD3 Ser9Gly polymorphism (rs6280) is pleiotropic, affecting reward as well as movement. PloS one. vol 8. issue 1. 2013-07-08. PMID:23365649. |
a linear regression analysis controlling for age, sex, diagnosis, and self-reported anhedonia indicated that during receipt of unpredictable monetary reward the glycine allele was associated with a greater reduction in d2/3 receptor binding (i.e., increased reward-related da release) in the middle (anterior) caudate (p<0.01) and the ventral striatum (p<0.05). |
2013-07-08 |
2023-08-12 |
human |
| Matthew N Hill, Kim G C Hellemans, Pamela Verma, Boris B Gorzalka, Joanne Weinber. Neurobiology of chronic mild stress: parallels to major depression. Neuroscience and biobehavioral reviews. vol 36. issue 9. 2013-03-14. PMID:22776763. |
the foundation of this model was that following long-term exposure to a series of mild, but unpredictable stressors, animals would develop a state of impaired reward salience that was akin to the anhedonia observed in major depressive disorder. |
2013-03-14 |
2023-08-12 |
Not clear |
| C Cinque, S Pondiki, D Oddi, M G Di Certo, S Marinelli, A Troisi, A Moles, F R D'Amat. Modeling socially anhedonic syndromes: genetic and pharmacological manipulation of opioid neurotransmission in mice. Translational psychiatry. vol 2. 2013-03-14. PMID:22929597. |
social anhedonia, or the diminished capacity to experience pleasure and reward from social affiliation, is a major symptom of different psychiatric disorders, including some forms of infantile autism and schizophrenia spectrum disorders. |
2013-03-14 |
2023-08-12 |
mouse |
| Anna Murphy, Eleanor Taylor, Rebecca Elliot. The detrimental effects of emotional process dysregulation on decision-making in substance dependence. Frontiers in integrative neuroscience. vol 6. 2012-11-20. PMID:23162443. |
we will explore theories of hyper and hypo sensitivity of the brain reward systems that may underpin motivational abnormalities and anhedonia. |
2012-11-20 |
2023-08-12 |
Not clear |
| C Nocjar, J Zhang, P Feng, J Panksep. The social defeat animal model of depression shows diminished levels of orexin in mesocortical regions of the dopamine system, and of dynorphin and orexin in the hypothalamus. Neuroscience. vol 218. 2012-11-16. PMID:22626650. |
two brain neuropeptides that have been implicated in anhedonia symptomology in preclinical depression models are dynorphin and orexin; which are concentrated along lateral hypothalamic dopamine reward pathways. |
2012-11-16 |
2023-08-12 |
rat |
| Tomoyuki Furuyashiki, Yuichi Deguch. [Roles of altered striatal function in major depression]. Brain and nerve = Shinkei kenkyu no shinpo. vol 64. issue 8. 2012-10-18. PMID:22868883. |
given the role of the striatum in behavioral learning with positive reinforcers, abnormalities as such suggest that impairment in reward processing and/or reinforcement learning in major depression is the basis of anhedonia and reduced psychomotor activity. |
2012-10-18 |
2023-08-12 |
human |
| Erin C Dowd, Deanna M Barc. Pavlovian reward prediction and receipt in schizophrenia: relationship to anhedonia. PloS one. vol 7. issue 5. 2012-09-10. PMID:22574121. |
reward processing abnormalities have been implicated in the pathophysiology of negative symptoms such as anhedonia and avolition in schizophrenia. |
2012-09-10 |
2023-08-12 |
human |
| Erin C Dowd, Deanna M Barc. Pavlovian reward prediction and receipt in schizophrenia: relationship to anhedonia. PloS one. vol 7. issue 5. 2012-09-10. PMID:22574121. |
individual difference analyses in patients revealed an association between physical anhedonia and activity in ventral striatum and ventromedial prefrontal cortex during anticipation of reward, in which greater anhedonia severity was associated with reduced activation to money versus no-money cues. |
2012-09-10 |
2023-08-12 |
human |
| Erin C Dowd, Deanna M Barc. Pavlovian reward prediction and receipt in schizophrenia: relationship to anhedonia. PloS one. vol 7. issue 5. 2012-09-10. PMID:22574121. |
these findings suggest that in the absence of response requirements, brain responses to reward receipt are largely intact in medicated individuals with chronic schizophrenia, while reward anticipation responses in left ventral striatum are reduced in those patients with greater anhedonia severity. |
2012-09-10 |
2023-08-12 |
human |
| Alex S Cohen, Dallas A Callaway, Gina M Najolia, Jeff T Larsen, Gregory P Straus. On "risk" and reward: investigating state anhedonia in psychometrically defined schizotypy and schizophrenia. Journal of abnormal psychology. vol 121. issue 2. 2012-08-06. PMID:22149913. |
on "risk" and reward: investigating state anhedonia in psychometrically defined schizotypy and schizophrenia. |
2012-08-06 |
2023-08-12 |
Not clear |
| Christopher G Ahnallen, Gabrielle I Liverant, Kristin L Gregor, Barbara W Kamholz, James J Levitt, Suzy Bird Gulliver, Diego A Pizzagalli, Vamsi K Koneru, Gary B Kapla. The relationship between reward-based learning and nicotine dependence in smokers with schizophrenia. Psychiatry research. vol 196. issue 1. 2012-07-24. PMID:22342123. |
among sws, reduced reward responsiveness and increased anhedonia were associated with and may contribute to greater co-occurring nicotine dependence. |
2012-07-24 |
2023-08-12 |
Not clear |
| Charlotte Keating, Alan J Tilbrook, Susan L Rossell, Peter G Enticott, Paul B Fitzgeral. Reward processing in anorexia nervosa. Neuropsychologia. vol 50. issue 5. 2012-07-20. PMID:22349445. |
theories explaining reward dysfunction have conventionally focused on anhedonia, describing that patients have an impaired ability to experience reward or pleasure. |
2012-07-20 |
2023-08-12 |
Not clear |
| Charlotte Keating, Alan J Tilbrook, Susan L Rossell, Peter G Enticott, Paul B Fitzgeral. Reward processing in anorexia nervosa. Neuropsychologia. vol 50. issue 5. 2012-07-20. PMID:22349445. |
recent brain imaging data on more complex reward processing tasks provide insights into fronto-striatal neural circuit dysfunction related to altered reward processing in an that challenges the relevance of anhedonia in explaining reward dysfunction in an. |
2012-07-20 |
2023-08-12 |
Not clear |
| Andre Der-Avakian, Athina Marko. The neurobiology of anhedonia and other reward-related deficits. Trends in neurosciences. vol 35. issue 1. 2012-05-15. PMID:22177980. |
here, we review the neural bases of the construct of anhedonia that reflects deficits in hedonic capacity and also closely linked to the constructs of reward valuation, decision-making, anticipation and motivation. |
2012-05-15 |
2023-08-12 |
Not clear |
| Andre Der-Avakian, Athina Marko. The neurobiology of anhedonia and other reward-related deficits. Trends in neurosciences. vol 35. issue 1. 2012-05-15. PMID:22177980. |
an understanding of anhedonia and other reward-related constructs will facilitate the diagnosis and treatment of disorders that include reward deficits as key symptoms. |
2012-05-15 |
2023-08-12 |
Not clear |
| Lindsey Sherdell, Christian E Waugh, Ian H Gotli. Anticipatory pleasure predicts motivation for reward in major depression. Journal of abnormal psychology. vol 121. issue 1. 2012-04-25. PMID:21842963. |
these findings support the formulation that anhedonia is not a unitary construct and suggest that, for depressed individuals, deficits in motivation for reward are driven primarily by low anticipatory pleasure and not by decreased consummatory liking. |
2012-04-25 |
2023-08-12 |
human |