Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Sophie R DelDonno, Anne L Weldon, Natania A Crane, Alessandra M Passarotti, Patrick J Pruitt, Laura B Gabriel, Wendy Yau, Kortni K Meyers, David T Hsu, Stephen F Taylor, Mary M Heitzeg, Ellen Herbener, Stewart A Shankman, Brian J Mickey, Jon-Kar Zubieta, Scott A Langenecke. Affective personality predictors of disrupted reward learning and pursuit in major depressive disorder. Psychiatry research. vol 230. issue 1. 2016-05-20. PMID:26319737. |
anhedonia, the diminished anticipation and pursuit of reward, is a core symptom of major depressive disorder (mdd). |
2016-05-20 |
2023-08-13 |
human |
Sophie R DelDonno, Anne L Weldon, Natania A Crane, Alessandra M Passarotti, Patrick J Pruitt, Laura B Gabriel, Wendy Yau, Kortni K Meyers, David T Hsu, Stephen F Taylor, Mary M Heitzeg, Ellen Herbener, Stewart A Shankman, Brian J Mickey, Jon-Kar Zubieta, Scott A Langenecke. Affective personality predictors of disrupted reward learning and pursuit in major depressive disorder. Psychiatry research. vol 230. issue 1. 2016-05-20. PMID:26319737. |
understanding individual reward processing deficits in mdd may inform personalized intervention addressing anhedonia and motivation deficits in select mdd patients. |
2016-05-20 |
2023-08-13 |
human |
N S Corral-Frías, Y S Nikolova, L J Michalski, D A A Baranger, A R Hariri, R Bogda. Stress-related anhedonia is associated with ventral striatum reactivity to reward and transdiagnostic psychiatric symptomatology. Psychological medicine. vol 45. issue 12. 2016-05-19. PMID:25853627. |
stress-related anhedonia is associated with ventral striatum reactivity to reward and transdiagnostic psychiatric symptomatology. |
2016-05-19 |
2023-08-13 |
Not clear |
T M Lancaster, E A Heerey, K Mantripragada, D E J Linde. Replication study implicates COMT val158met polymorphism as a modulator of probabilistic reward learning. Genes, brain, and behavior. vol 14. issue 6. 2016-05-10. PMID:26096878. |
our findings may have implications for neuropsychiatric disorders characterized by clinical deficits in reward processing such as anhedonia. |
2016-05-10 |
2023-08-13 |
Not clear |
Astrid K Stoker, Michael J Marks, Athina Marko. Null mutation of the β2 nicotinic acetylcholine receptor subunit attenuates nicotine withdrawal-induced anhedonia in mice. European journal of pharmacology. vol 753. 2016-03-14. PMID:25107281. |
anhedonia was assessed with brain reward thresholds, defined as the current intensity that supports operant behavior in the discrete-trial current-intensity intracranial self-stimulation procedure. |
2016-03-14 |
2023-08-13 |
mouse |
Julie M McCarthy, Michael T Treadway, Jack J Blanchar. Motivation and effort in individuals with social anhedonia. Schizophrenia research. vol 165. issue 1. 2016-02-01. PMID:25888337. |
it has been proposed that anhedonia may, in part, reflect difficulties in reward processing and effortful decision making. |
2016-02-01 |
2023-08-13 |
human |
Julie M McCarthy, Michael T Treadway, Jack J Blanchar. Motivation and effort in individuals with social anhedonia. Schizophrenia research. vol 165. issue 1. 2016-02-01. PMID:25888337. |
contrary to our expectations, when the probability of reward was most uncertain (50% probability), at low and medium reward values, the social anhedonia group demonstrated more effortful decision making than either individuals high in positive schizotypy or controls. |
2016-02-01 |
2023-08-13 |
human |
Julie M McCarthy, Michael T Treadway, Jack J Blanchar. Motivation and effort in individuals with social anhedonia. Schizophrenia research. vol 165. issue 1. 2016-02-01. PMID:25888337. |
our results suggest that social anhedonia is related to intact motivation and effort for monetary rewards, but that individuals with this characteristic display a unique and perhaps inefficient pattern of effort allocation when the probability of reward is most uncertain. |
2016-02-01 |
2023-08-13 |
human |
Emily A Ferenczi, Kelly A Zalocusky, Conor Liston, Logan Grosenick, Melissa R Warden, Debha Amatya, Kiefer Katovich, Hershel Mehta, Brian Patenaude, Charu Ramakrishnan, Paul Kalanithi, Amit Etkin, Brian Knutson, Gary H Glover, Karl Deisserot. Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior. Science (New York, N.Y.). vol 351. issue 6268. 2016-01-19. PMID:26722001. |
motivation for reward drives adaptive behaviors, whereas impairment of reward perception and experience (anhedonia) can contribute to psychiatric diseases, including depression and schizophrenia. |
2016-01-19 |
2023-08-13 |
rat |
Laura Nawijn, Mirjam van Zuiden, Jessie L Frijling, Saskia B J Koch, Dick J Veltman, Miranda Olf. Reward functioning in PTSD: a systematic review exploring the mechanisms underlying anhedonia. Neuroscience and biobehavioral reviews. vol 51. 2015-12-01. PMID:25639225. |
reward functioning in ptsd: a systematic review exploring the mechanisms underlying anhedonia. |
2015-12-01 |
2023-08-13 |
human |
Laura Nawijn, Mirjam van Zuiden, Jessie L Frijling, Saskia B J Koch, Dick J Veltman, Miranda Olf. Reward functioning in PTSD: a systematic review exploring the mechanisms underlying anhedonia. Neuroscience and biobehavioral reviews. vol 51. 2015-12-01. PMID:25639225. |
an important diagnostic feature of ptsd is anhedonia, which may result from deficits in reward functioning. |
2015-12-01 |
2023-08-13 |
human |
Joshua B B Garfield, Nicholas B Allen, Ali Cheetham, Julian G Simmons, Dan I Lubma. Attention to pleasant stimuli in early adolescence predicts alcohol-related problems in mid-adolescence. Biological psychology. vol 108. 2015-11-30. PMID:25818044. |
these findings further support research indicating that increased reward responsiveness predicts risky behaviours in adolescence, with anhedonia primarily a consequence of substance dependence. |
2015-11-30 |
2023-08-13 |
human |
Tsafrir Greenberg, Henry W Chase, Jorge R Almeida, Richelle Stiffler, Carlos R Zevallos, Haris A Aslam, Thilo Deckersbach, Sarah Weyandt, Crystal Cooper, Marisa Toups, Thomas Carmody, Benji Kurian, Scott Peltier, Phillip Adams, Melvin G McInnis, Maria A Oquendo, Patrick J McGrath, Maurizio Fava, Myrna Weissman, Ramin Parsey, Madhukar H Trivedi, Mary L Phillip. Moderation of the Relationship Between Reward Expectancy and Prediction Error-Related Ventral Striatal Reactivity by Anhedonia in Unmedicated Major Depressive Disorder: Findings From the EMBARC Study. The American journal of psychiatry. vol 172. issue 9. 2015-11-20. PMID:26183698. |
moderation of the relationship between reward expectancy and prediction error-related ventral striatal reactivity by anhedonia in unmedicated major depressive disorder: findings from the embarc study. |
2015-11-20 |
2023-08-13 |
Not clear |
Tsafrir Greenberg, Henry W Chase, Jorge R Almeida, Richelle Stiffler, Carlos R Zevallos, Haris A Aslam, Thilo Deckersbach, Sarah Weyandt, Crystal Cooper, Marisa Toups, Thomas Carmody, Benji Kurian, Scott Peltier, Phillip Adams, Melvin G McInnis, Maria A Oquendo, Patrick J McGrath, Maurizio Fava, Myrna Weissman, Ramin Parsey, Madhukar H Trivedi, Mary L Phillip. Moderation of the Relationship Between Reward Expectancy and Prediction Error-Related Ventral Striatal Reactivity by Anhedonia in Unmedicated Major Depressive Disorder: Findings From the EMBARC Study. The American journal of psychiatry. vol 172. issue 9. 2015-11-20. PMID:26183698. |
anhedonia, disrupted reward processing, is a core symptom of major depressive disorder. |
2015-11-20 |
2023-08-13 |
Not clear |
Tsafrir Greenberg, Henry W Chase, Jorge R Almeida, Richelle Stiffler, Carlos R Zevallos, Haris A Aslam, Thilo Deckersbach, Sarah Weyandt, Crystal Cooper, Marisa Toups, Thomas Carmody, Benji Kurian, Scott Peltier, Phillip Adams, Melvin G McInnis, Maria A Oquendo, Patrick J McGrath, Maurizio Fava, Myrna Weissman, Ramin Parsey, Madhukar H Trivedi, Mary L Phillip. Moderation of the Relationship Between Reward Expectancy and Prediction Error-Related Ventral Striatal Reactivity by Anhedonia in Unmedicated Major Depressive Disorder: Findings From the EMBARC Study. The American journal of psychiatry. vol 172. issue 9. 2015-11-20. PMID:26183698. |
the authors examined the effect of anhedonia on reward expectancy (expected outcome value) and prediction error- (discrepancy between expected and actual outcome) related ventral striatal reactivity, as well as the relationship between these measures. |
2015-11-20 |
2023-08-13 |
Not clear |
T M Lancaster, E A Heerey, K Mantripragada, D E J Linde. CACNA1C risk variant affects reward responsiveness in healthy individuals. Translational psychiatry. vol 4. 2015-11-02. PMID:25290268. |
impaired reward processing may be a transdiagnostic phenotype of variation in cacna1c that could contribute to anhedonia and other clinical features common to both affective and psychotic disorders. |
2015-11-02 |
2023-08-13 |
Not clear |
N Lally, A C Nugent, D A Luckenbaugh, R Ameli, J P Roiser, C A Zarat. Anti-anhedonic effect of ketamine and its neural correlates in treatment-resistant bipolar depression. Translational psychiatry. vol 4. 2015-11-02. PMID:25313512. |
however, evidence suggests that standard treatments for depression do little to alleviate the symptoms of anhedonia and may cause reward blunting. |
2015-11-02 |
2023-08-13 |
Not clear |
Kristine Rømer Thomse. Measuring anhedonia: impaired ability to pursue, experience, and learn about reward. Frontiers in psychology. vol 6. 2015-10-07. PMID:26441781. |
measuring anhedonia: impaired ability to pursue, experience, and learn about reward. |
2015-10-07 |
2023-08-13 |
Not clear |
Gonzalo Arrondo, Nuria Segarra, Antonio Metastasio, Hisham Ziauddeen, Jennifer Spencer, Niels R Reinders, Robert B Dudas, Trevor W Robbins, Paul C Fletcher, Graham K Murra. Reduction in ventral striatal activity when anticipating a reward in depression and schizophrenia: a replicated cross-diagnostic finding. Frontiers in psychology. vol 6. 2015-09-18. PMID:26379600. |
we hypothesized that the two clinical groups would have a reduced activity in the ventral striatum when anticipating reward (compared to anticipation of a neutral outcome) and that striatal activation would correlate with clinical measures of motivational problems and anhedonia. |
2015-09-18 |
2023-08-13 |
human |
Adam M Leventhal, Michael Trujillo, Katherine J Ameringer, Jennifer W Tidey, Steve Sussman, Christopher W Kahle. Anhedonia and the relative reward value of drug and nondrug reinforcers in cigarette smokers. Journal of abnormal psychology. vol 123. issue 2. 2015-09-03. PMID:24886011. |
anhedonia and the relative reward value of drug and nondrug reinforcers in cigarette smokers. |
2015-09-03 |
2023-08-13 |
human |