| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Or Burstein, Motty Franko, Eyal Gale, Assaf Handelsman, Segev Barak, Shai Motsan, Alon Shamir, Roni Toledano, Omri Simhon, Yafit Hirshler, Gang Chen, Ravid Doro. Escitalopram and NHT normalized stress-induced anhedonia and molecular neuroadaptations in a mouse model of depression. PloS one. vol 12. issue 11. 2017-12-26. PMID:29141007. |
anxiety and mood disorders have been previously associated with dysregulation of the reward system, with anhedonia as a core element of major depressive disorder (mdd). |
2017-12-26 |
2023-08-13 |
mouse |
| Joshua J Ahles, Amy H Mezulis, Sheila E Crowel. Pre-ejection period reactivity to reward is associated with anhedonic symptoms of depression among adolescents. Developmental psychobiology. vol 59. issue 4. 2017-12-20. PMID:28407206. |
pre-ejection period (pep) reactivity to reward has been posited as a specific index of behavioral approach and incentive motivation, suggesting it might be uniquely associated with the affective and motivational deficits of anhedonia. |
2017-12-20 |
2023-08-13 |
human |
| Joshua J Ahles, Amy H Mezulis, Sheila E Crowel. Pre-ejection period reactivity to reward is associated with anhedonic symptoms of depression among adolescents. Developmental psychobiology. vol 59. issue 4. 2017-12-20. PMID:28407206. |
this study found marginal support for an association between pep reactivity to reward and concurrent anhedonia symptoms, but no association with nonanhedonic or the global scale. |
2017-12-20 |
2023-08-13 |
human |
| C B Young, T Chen, R Nusslock, J Keller, A F Schatzberg, V Meno. Anhedonia and general distress show dissociable ventromedial prefrontal cortex connectivity in major depressive disorder. Translational psychiatry. vol 6. 2017-11-16. PMID:27187232. |
our findings demonstrate that anhedonia in mdd is associated with context-specific deficits in pvmpfc connectivity with the mesolimbic reward system when encountering pleasurable stimuli, rather than a static deficit in intrinsic resting-state connectivity. |
2017-11-16 |
2023-08-13 |
Not clear |
| Zimri S Yaseen, Igor I Galynker, Jessica Briggs, Rachel D Freed, Vilma Gabba. Functional domains as correlates of suicidality among psychiatric inpatients. Journal of affective disorders. vol 203. 2017-11-06. PMID:27280966. |
specifically, we examined anhedonia, anxiety/entrapment, and attachment disturbances, reflecting disturbances in reward processes, negative valence systems, and social processes, respectively. |
2017-11-06 |
2023-08-13 |
Not clear |
| D Borsook, C Linnman, V Faria, A M Strassman, L Becerra, I Elma. Reward deficiency and anti-reward in pain chronification. Neuroscience and biobehavioral reviews. vol 68. 2017-10-23. PMID:27246519. |
thus, reward deficiency (rd) represents a within-system neuroadaptation to pain-induced protracted activation of the reward circuits that leads to depletion-like hypodopaminergia, clinically manifested anhedonia, and diminished motivation for natural reinforcers. |
2017-10-23 |
2023-08-13 |
Not clear |
| Alena Becker, Anna M Ehret, Peter Kirsc. From the neurobiological basis of comorbid alcohol dependence and depression to psychological treatment strategies: study protocol of a randomized controlled trial. BMC psychiatry. vol 17. issue 1. 2017-10-23. PMID:28454522. |
past research suggests that symptoms such as craving and anhedonia might be associated with alterations within the reward circuit, while emotion regulation deficits are related to disruptions within the default mode network. |
2017-10-23 |
2023-08-13 |
Not clear |
| A S Huhn, R E Meyer, J D Harris, H Ayaz, E Deneke, D M Stankoski, S C Bunc. Evidence of anhedonia and differential reward processing in prefrontal cortex among post-withdrawal patients with prescription opiate dependence. Brain research bulletin. vol 123. 2017-10-20. PMID:26711857. |
evidence of anhedonia and differential reward processing in prefrontal cortex among post-withdrawal patients with prescription opiate dependence. |
2017-10-20 |
2023-08-13 |
human |
| Sakina J Rizvi, Diego A Pizzagalli, Beth A Sproule, Sidney H Kenned. Assessing anhedonia in depression: Potentials and pitfalls. Neuroscience and biobehavioral reviews. vol 65. 2017-10-19. PMID:26959336. |
the majority of research regarding anhedonia and its neurobiological underpinnings comes from preclinical research, which uses primary reward (e.g. |
2017-10-19 |
2023-08-13 |
Not clear |
| Bei Zhang, Pan Lin, Huqing Shi, Dost Öngür, Randy P Auerbach, Xiaosheng Wang, Shuqiao Yao, Xiang Wan. Mapping anhedonia-specific dysfunction in a transdiagnostic approach: an ALE meta-analysis. Brain imaging and behavior. vol 10. issue 3. 2017-10-16. PMID:26487590. |
these results support that anhedonia is characterized by alterations in reward processing and relies on frontal-striatal brain circuitry. |
2017-10-16 |
2023-08-13 |
Not clear |
| Muhammad A Parvaz, Vilma Gabbay, Pias Malaker, Rita Z Goldstei. Objective and specific tracking of anhedonia via event-related potentials in individuals with cocaine use disorders. Drug and alcohol dependence. vol 164. 2017-10-16. PMID:27226335. |
hyposensitivity to non-drug reward, behaviorally manifested as anhedonia, is a hallmark of chronic substance use. |
2017-10-16 |
2023-08-13 |
Not clear |
| Muhammad A Parvaz, Vilma Gabbay, Pias Malaker, Rita Z Goldstei. Objective and specific tracking of anhedonia via event-related potentials in individuals with cocaine use disorders. Drug and alcohol dependence. vol 164. 2017-10-16. PMID:27226335. |
anhedonia is a transdiagnostic symptom underpinned by neurobiochemical disturbances in the reward circuit, yet an objective measure to assess anhedonia severity still eludes the field. |
2017-10-16 |
2023-08-13 |
Not clear |
| Muhammad A Parvaz, Vilma Gabbay, Pias Malaker, Rita Z Goldstei. Objective and specific tracking of anhedonia via event-related potentials in individuals with cocaine use disorders. Drug and alcohol dependence. vol 164. 2017-10-16. PMID:27226335. |
we hypothesized that the reward positivity (rewp) component of the event-related potentials (erps) will specifically track anhedonia as the rewp is attributed to the same brain regions that are also implicated in anhedonia. |
2017-10-16 |
2023-08-13 |
Not clear |
| Jasmine Carter, Walter Swardfage. Mood and metabolism: Anhedonia as a clinical target in Type 2 diabetes. Psychoneuroendocrinology. vol 69. 2017-09-13. PMID:27088371. |
examinations of depressive symptoms by dimension have suggested that anhedonia, the inability to anticipate, seek, choose and enjoy reward, may be of particular clinical importance. |
2017-09-13 |
2023-08-13 |
Not clear |
| Jasmine Carter, Walter Swardfage. Mood and metabolism: Anhedonia as a clinical target in Type 2 diabetes. Psychoneuroendocrinology. vol 69. 2017-09-13. PMID:27088371. |
structural and functional brain changes in type 2 diabetes distributed throughout the principally dopaminergic reward circuitry suggest a neurobiological basis for motivational and decisional aspects of anhedonia. |
2017-09-13 |
2023-08-13 |
Not clear |
| Jessica Bryant, E Samuel Winer, Taban Salem, Michael R Nadorf. Struggling toward reward: Recent experience of anhedonia interacts with motivation to predict reward pursuit in the face of a stressful manipulation. PloS one. vol 12. issue 3. 2017-08-25. PMID:28273126. |
struggling toward reward: recent experience of anhedonia interacts with motivation to predict reward pursuit in the face of a stressful manipulation. |
2017-08-25 |
2023-08-13 |
human |
| Jessica Bryant, E Samuel Winer, Taban Salem, Michael R Nadorf. Struggling toward reward: Recent experience of anhedonia interacts with motivation to predict reward pursuit in the face of a stressful manipulation. PloS one. vol 12. issue 3. 2017-08-25. PMID:28273126. |
at low levels of anhedonia, action orientation was associated with effort for reward, but this relationship was not present at high levels of anhedonia. |
2017-08-25 |
2023-08-13 |
human |
| Anup Sharma, Daniel H Wolf, Rastko Ciric, Joseph W Kable, Tyler M Moore, Simon N Vandekar, Natalie Katchmar, Aylin Daldal, Kosha Ruparel, Christos Davatzikos, Mark A Elliott, Monica E Calkins, Russell T Shinohara, Danielle S Bassett, Theodore D Satterthwait. Common Dimensional Reward Deficits Across Mood and Psychotic Disorders: A Connectome-Wide Association Study. The American journal of psychiatry. vol 174. issue 7. 2017-07-10. PMID:28135847. |
a dimensional conceptualization posits that anhedonia severity is related to a transdiagnostic continuum of reward deficits in specific neural networks. |
2017-07-10 |
2023-08-13 |
Not clear |
| Jennifer C Felge. The Role of Dopamine in Inflammation-Associated Depression: Mechanisms and Therapeutic Implications. Current topics in behavioral neurosciences. vol 31. 2017-06-20. PMID:27225499. |
findings have included inflammation-associated reductions in ventral striatal responses to hedonic reward, decreased dopamine and dopamine metabolites in cerebrospinal fluid, and decreased availability of striatal dopamine, all of which correlate with symptoms of anhedonia, fatigue, and psychomotor retardation. |
2017-06-20 |
2023-08-13 |
Not clear |
| Jennifer C Felge. The Role of Dopamine in Inflammation-Associated Depression: Mechanisms and Therapeutic Implications. Current topics in behavioral neurosciences. vol 31. 2017-06-20. PMID:27225499. |
similar relationships between alterations in dopamine-relevant corticostriatal reward circuitry and symptoms of anhedonia and psychomotor slowing have also been observed in patients with major depression who exhibit increased peripheral cytokines and other inflammatory markers, such as c-reactive protein. |
2017-06-20 |
2023-08-13 |
Not clear |