| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Diego A Pizzagall. Depression, stress, and anhedonia: toward a synthesis and integrated model. Annual review of clinical psychology. vol 10. 2014-11-18. PMID:24471371. |
here, a heuristic model is presented postulating that anhedonia arises from dysfunctional interactions between stress and brain reward systems. |
2014-11-18 |
2023-08-12 |
Not clear |
| Amitai Abramovitch, Diego A Pizzagalli, Lillian Reuman, Sabine Wilhel. Anhedonia in obsessive-compulsive disorder: beyond comorbid depression. Psychiatry research. vol 216. issue 2. 2014-10-30. PMID:24564999. |
obsessive-compulsive disorder (ocd) has been linked to reward dysfunctions, highlighting a possible role of anhedonia in ocd. |
2014-10-30 |
2023-08-12 |
Not clear |
| Amitai Abramovitch, Diego A Pizzagalli, Lillian Reuman, Sabine Wilhel. Anhedonia in obsessive-compulsive disorder: beyond comorbid depression. Psychiatry research. vol 216. issue 2. 2014-10-30. PMID:24564999. |
future research is needed to address the unique interface between anhedonia and reward responsiveness in ocd. |
2014-10-30 |
2023-08-12 |
Not clear |
| Ernest Mas-Herrero, Robert J Zatorre, Antoni Rodriguez-Fornells, Josep Marco-Pallaré. Dissociation between musical and monetary reward responses in specific musical anhedonia. Current biology : CB. vol 24. issue 6. 2014-10-07. PMID:24613311. |
dissociation between musical and monetary reward responses in specific musical anhedonia. |
2014-10-07 |
2023-08-12 |
human |
| Ernest Mas-Herrero, Robert J Zatorre, Antoni Rodriguez-Fornells, Josep Marco-Pallaré. Dissociation between musical and monetary reward responses in specific musical anhedonia. Current biology : CB. vol 24. issue 6. 2014-10-07. PMID:24613311. |
these results point to the existence of specific musical anhedonia and suggest that there may be individual differences in access to the reward system. |
2014-10-07 |
2023-08-12 |
human |
| Camilla N Clark, Laura E Downey, Jason D Warre. Music biology: all this useful beauty. Current biology : CB. vol 24. issue 6. 2014-10-07. PMID:24650910. |
such 'musical anhedonia' implies the existence of music-specific brain reward mechanisms, which could provide a substrate for music to acquire biological value. |
2014-10-07 |
2023-08-12 |
Not clear |
| Margherita Zotti, Paolo Tucci, Marilena Colaianna, Maria Grazia Morgese, Emanuela Mhillaj, Stefania Schiavone, Sergio Scaccianoce, Vincenzo Cuomo, Luigia Trabac. Chronic nandrolone administration induces dysfunction of the reward pathway in rats. Steroids. vol 79. 2014-08-26. PMID:24490270. |
the chronic administration of nandrolone, at 5 mg kg(-1) injected daily for 4 weeks, induced the loss of sweet taste preference, a sign of anhedonia and dysfunction of the reward pathway. |
2014-08-26 |
2023-08-12 |
rat |
| R Gaillard, D Gourion, P M Llorc. [Anhedonia in depression]. L'Encephale. vol 39. issue 4. 2014-06-25. PMID:23937895. |
now, the construct of anhedonia reflects deficits in hedonic capacity, and is closely linked to the processes of reward valuation, decision-making, anticipation, and motivation. |
2014-06-25 |
2023-08-12 |
Not clear |
| Peng Zhong, Xiaojie Liu, Zhen Zhang, Ying Hu, Sarah J Liu, Martha Lezama-Ruiz, Milan Joksimovic, Qing-song Li. Cyclin-dependent kinase 5 in the ventral tegmental area regulates depression-related behaviors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 18. 2014-06-23. PMID:24790206. |
dopamine neurons in the ventral tegmental area (vta) govern reward and motivation and dysregulated dopaminergic transmission may account for anhedonia and other symptoms of depression. |
2014-06-23 |
2023-08-13 |
mouse |
| Zhixiang Liu, Jingfeng Zhou, Yi Li, Fei Hu, Yao Lu, Ming Ma, Qiru Feng, Ju-En Zhang, Daqing Wang, Jiawei Zeng, Junhong Bao, Ji-Young Kim, Zhou-Feng Chen, Salah El Mestikawy, Minmin Lu. Dorsal raphe neurons signal reward through 5-HT and glutamate. Neuron. vol 81. issue 6. 2014-05-21. PMID:24656254. |
these experiments demonstrate the ability of drn neurons to organize reward behaviors and might provide insights into the underlying mechanisms of learning facilitation and anhedonia treatment. |
2014-05-21 |
2023-08-12 |
mouse |
| Crystal Edler Schiller, Jared Minkel, Moria J Smoski, Gabriel S Dichte. Remitted major depression is characterized by reduced prefrontal cortex reactivity to reward loss. Journal of affective disorders. vol 151. issue 2. 2014-05-13. PMID:23835103. |
although a growing body of literature has linked anhedonia in mdd to reduced frontostriatal activity during reward gains, relatively few studies have examined neural responsivity to loss, and no studies to date have examined neural responses to loss in euthymic individuals with a history of mdd. |
2014-05-13 |
2023-08-12 |
Not clear |
| Vilma Gabbay, Benjamin A Ely, Qingyang Li, Saroja D Bangaru, Aviva M Panzer, Carmen M Alonso, F Xavier Castellanos, Michael P Milha. Striatum-based circuitry of adolescent depression and anhedonia. Journal of the American Academy of Child and Adolescent Psychiatry. vol 52. issue 6. 2014-05-05. PMID:23702452. |
striatum-based circuits have been implicated in both major depressive disorder (mdd) and anhedonia, a symptom that reflects deficits of reward processing. |
2014-05-05 |
2023-08-12 |
Not clear |
| Jennifer Keller, Christina B Young, Elizabeth Kelley, Katherine Prater, Daniel J Levitin, Vinod Meno. Trait anhedonia is associated with reduced reactivity and connectivity of mesolimbic and paralimbic reward pathways. Journal of psychiatric research. vol 47. issue 10. 2014-04-04. PMID:23791396. |
trait anhedonia is associated with reduced reactivity and connectivity of mesolimbic and paralimbic reward pathways. |
2014-04-04 |
2023-08-12 |
human |
| Jennifer Keller, Christina B Young, Elizabeth Kelley, Katherine Prater, Daniel J Levitin, Vinod Meno. Trait anhedonia is associated with reduced reactivity and connectivity of mesolimbic and paralimbic reward pathways. Journal of psychiatric research. vol 47. issue 10. 2014-04-04. PMID:23791396. |
we found that trait anhedonia was negatively correlated with pleasantness ratings of music stimuli and with activation of key brain structures involved in reward processing, including nucleus accumbens (nac), basal forebrain and hypothalamus which are linked by the medial forebrain bundle to the ventral tegmental area (vta). |
2014-04-04 |
2023-08-12 |
human |
| Jennifer Keller, Christina B Young, Elizabeth Kelley, Katherine Prater, Daniel J Levitin, Vinod Meno. Trait anhedonia is associated with reduced reactivity and connectivity of mesolimbic and paralimbic reward pathways. Journal of psychiatric research. vol 47. issue 10. 2014-04-04. PMID:23791396. |
our results indicate that trait anhedonia is associated with reduced reactivity and connectivity of mesolimbic and related limbic and paralimbic systems involved in reward processing. |
2014-04-04 |
2023-08-12 |
human |
| Bo Jiang, Wei Wang, Fang Wang, Zhuang-Li Hu, Jun-Li Xiao, Si Yang, Jing Zhang, Xiao-Zhong Peng, Jin-Hui Wang, Jian-Guo Che. The stability of NR2B in the nucleus accumbens controls behavioral and synaptic adaptations to chronic stress. Biological psychiatry. vol 74. issue 2. 2014-01-17. PMID:23260228. |
it has been demonstrated that the glutamatergic system in nac plays an important role in the reward pathway, dysfunction of which would cause anhedonia, a core symptom of depression. |
2014-01-17 |
2023-08-12 |
Not clear |
| S R Kuhlmann, H Walter, T E Schläpfe. [The neurobiology of anhedonia. The pathophysiology of an important symptom in depressive disorders]. Der Nervenarzt. vol 84. issue 5. 2014-01-08. PMID:23086440. |
the hypothesis that functional changes within the mesolimbic reward system could represent the neural correlate of anhedonia has contributed to a new concept of depressive disorders and allows testing of new therapeutic options for patients suffering from very resistant forms of depression. |
2014-01-08 |
2023-08-12 |
Not clear |
| S R Kuhlmann, H Walter, T E Schläpfe. [The neurobiology of anhedonia. The pathophysiology of an important symptom in depressive disorders]. Der Nervenarzt. vol 84. issue 5. 2014-01-08. PMID:23086440. |
by using the method of deep brain stimulation present clinical studies try to ascertain whether the symptom of anhedonia can be alleviated by influencing the neural activity of the reward system. |
2014-01-08 |
2023-08-12 |
Not clear |
| J M Bessa, M Morais, F Marques, L Pinto, J A Palha, O F X Almeida, N Sous. Stress-induced anhedonia is associated with hypertrophy of medium spiny neurons of the nucleus accumbens. Translational psychiatry. vol 3. 2013-12-23. PMID:23736119. |
as the nac is a key component in the neural circuitry of reward, it has been hypothesized that anhedonia, a core symptom of depression, might be related to dysfunction of this brain region. |
2013-12-23 |
2023-08-12 |
rat |
| Scott J Russo, Eric J Nestle. The brain reward circuitry in mood disorders. Nature reviews. Neuroscience. vol 14. issue 9. 2013-12-11. PMID:23942470. |
a recent literature has identified important structural and functional alterations within the brain's reward circuitry--particularly in the ventral tegmental area-nucleus accumbens pathway--that are associated with symptoms such as anhedonia and aberrant reward-associated perception and memory. |
2013-12-11 |
2023-08-12 |
human |