| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Liu-Lin Xiong, Li Chen, Isaac Bul Deng, Xin-Fu Zhou, Ting-Hua Wan. P75 neurotrophin receptor as a therapeutic target for drug development to treat neurological diseases. The European journal of neuroscience. 2022-08-26. PMID:36017737. |
the interaction of neurotrophins with their receptors is involved in the pathogenesis and progression of various neurological diseases, including alzheimer's disease (ad), parkinson's disease (pd), amyotrophic lateral sclerosis (als), spinal cord injury, and acute and chronic cerebral damage, etc. |
2022-08-26 |
2023-08-14 |
Not clear |
| Gordon S Mitchell, Tracy L Bake. Respiratory neuroplasticity: Mechanisms and translational implications of phrenic motor plasticity. Handbook of clinical neurology. vol 188. 2022-08-14. PMID:35965036. |
advances in our understanding of these novel and important forms of plasticity have been rapid and have already inspired translation in multiple respects: (1) development of novel therapeutic strategies to preserve/restore breathing function in humans with severe neurological disorders, such as spinal cord injury and amyotrophic lateral sclerosis; and (2) the discovery that similar plasticity also occurs in nonrespiratory motor systems. |
2022-08-14 |
2023-08-14 |
Not clear |
| Pan Si, Chenkai Zh. Biological and neurological activities of astaxanthin (Review). Molecular medicine reports. vol 26. issue 4. 2022-08-10. PMID:35946443. |
owing to its ability to cross the blood‑brain barrier, astaxanthin has received attention for its protective effects against neurological disorders, including alzheimer's disease, parkinson's disease, amyotrophic lateral sclerosis, cerebral ischemia/reperfusion, subarachnoid hemorrhage, traumatic brain injury, spinal cord injury, cognitive impairment and neuropathic pain. |
2022-08-10 |
2023-08-14 |
Not clear |
| Ivan Rulik, Md Samiul Haque Sunny, Javier Dario Sanjuan De Caro, Md Ishrak Islam Zarif, Brahim Brahmi, Sheikh Iqbal Ahamed, Katie Schultz, Inga Wang, Tony Leheng, Jason Peng Longxiang, Mohammad H Rahma. Control of a Wheelchair-Mounted 6DOF Assistive Robot With Chin and Finger Joysticks. Frontiers in robotics and AI. vol 9. 2022-08-08. PMID:35937617. |
people with limited upper limb function due to stroke, spinal cord injury, cerebral palsy, amyotrophic lateral sclerosis, and other conditions find the controls of assistive devices such as power wheelchairs difficult to use. |
2022-08-08 |
2023-08-14 |
Not clear |
| Yining Zhu, Yining Xu, Rongrong Xuan, Jialu Huang, Bíró István, Gusztáv Fekete, Yaodong G. Mixed Comparison of Different Exercise Interventions for Function, Respiratory, Fatigue, and Quality of Life in Adults With Amyotrophic Lateral Sclerosis: Systematic Review and Network Meta-Analysis. Frontiers in aging neuroscience. vol 14. 2022-07-28. PMID:35898325. |
amyotrophic lateral sclerosis (als) is a progressive neuromuscular disease whose primary hallmark is the progressive degeneration of motor neurons in the brainstem, spinal cord, and cerebral cortex that leads to weakness, spasticity, fatigue, skeletal muscle atrophy, paralysis, and even death. |
2022-07-28 |
2023-08-14 |
Not clear |
| Qianqian Zhang, Huihui Zhao, Maotao Luo, Xi Cheng, Yanan Li, Qingyang Li, Zheng Wang, Qi Ni. The Classification and Prediction of Ferroptosis-Related Genes in ALS: A Pilot Study. Frontiers in genetics. vol 13. 2022-07-25. PMID:35873477. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by progressive muscle paralysis, which is followed by degeneration of motor neurons in the motor cortex of the brainstem and spinal cord. |
2022-07-25 |
2023-08-14 |
Not clear |
| Evelien Van Schoor, Simona Ospitalieri, Sebastiaan Moonen, Sandra O Tomé, Alicja Ronisz, Orkun Ok, Jochen Weishaupt, Albert C Ludolph, Philip Van Damme, Ludo Van Den Bosch, Dietmar Rudolf Tha. Increased pyroptosis activation in white matter microglia is associated with neuronal loss in ALS motor cortex. Acta neuropathologica. 2022-07-22. PMID:35867112. |
amyotrophic lateral sclerosis (als) is characterized by the degeneration of motor neurons in the motor cortex, brainstem, and spinal cord. |
2022-07-22 |
2023-08-14 |
Not clear |
| Jessica M Collins, Rachel A K Atkinson, Lyzette M Matthews, Isabella C Murray, Sharn E Perry, Anna E Kin. Sarm1 knockout modifies biomarkers of neurodegeneration and spinal cord circuitry but not disease progression in the mSOD1 Neurobiology of disease. 2022-07-21. PMID:35863521. |
sarm1 knockout modifies biomarkers of neurodegeneration and spinal cord circuitry but not disease progression in the msod1 the mechanisms underlying the loss of motor neuron axon integrity in amyotrophic lateral sclerosis (als) are unclear. |
2022-07-21 |
2023-08-14 |
Not clear |
| Yiyan Sun, Xiaohuan Xia, Diksha Basnet, Jialin C Zheng, Jian Huang, Jianhui Li. Mechanisms of Ferroptosis and Emerging Links to the Pathology of Neurodegenerative Diseases. Frontiers in aging neuroscience. vol 14. 2022-07-15. PMID:35837484. |
neurodegenerative diseases are a diverse class of diseases attributed to chronic progressive neuronal degeneration and synaptic loss in the brain and/or spinal cord, including alzheimer's disease, parkinson's disease, huntington's disease, amyotrophic lateral sclerosis and multiple sclerosis. |
2022-07-15 |
2023-08-14 |
Not clear |
| Abdul Waris, Asmat Ali, Atta Ullah Khan, Muhammad Asim, Doaa Zamel, Kinza Fatima, Abdur Raziq, Muhammad Ajmal Khan, Nazia Akbar, Abdul Baset, Mohammed A S Aboureha. Applications of Various Types of Nanomaterials for the Treatment of Neurological Disorders. Nanomaterials (Basel, Switzerland). vol 12. issue 13. 2022-07-09. PMID:35807977. |
neurological disorders include alzheimer's disease, parkinson's disease, huntington's disease, amyotrophic lateral sclerosis, frontotemporal dementia, prion disease, brain tumor, spinal cord injury, and stroke. |
2022-07-09 |
2023-08-14 |
Not clear |
| Wentao Duan, Dan Zeng, Jin Huang, Jing Gu, San Li, Wei Zhou, Jinling Ma, Yan Jiang, Liming Zhu, Xudong Xiang, Aiguo Da. Effect of modified Total Body Recumbent Stepper training on exercise capacity and thioredoxin in COPD: a randomized clinical trial. Scientific reports. vol 12. issue 1. 2022-07-01. PMID:35778539. |
the modified total body recumbent stepper (tbrs, nustep-t4) can benefit patients with stroke, spinal cord injury and amyotrophic lateral sclerosis. |
2022-07-01 |
2023-08-14 |
human |
| Kelsey L Krus, Amy Strickland, Yurie Yamada, Laura Devault, Robert E Schmidt, A Joseph Bloom, Jeffrey Milbrandt, Aaron DiAntoni. Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy. Cell reports. vol 39. issue 13. 2022-06-29. PMID:35767949. |
tdp-43 mediates proper stathmin-2 (stmn2) mrna splicing, and stmn2 protein is reduced in the spinal cord of most patients with amyotrophic lateral sclerosis (als). |
2022-06-29 |
2023-08-14 |
mouse |
| Gabriela Bortolança Chiarotto, Luciana Politti Cartarozzi, Matheus Perez, Ana Laura Midori Rossi Tomiyama, Mateus Vidigal de Castro, Adriana S S Duarte, Ângela Cristina Malheiros Luzo, Alexandre Leite Rodrigues de Oliveir. Delayed onset, immunomodulation, and lifespan improvement of SOD1 Brain research bulletin. 2022-06-19. PMID:35718222. |
delayed onset, immunomodulation, and lifespan improvement of sod1 amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the selective and progressive loss of motor neurons from the spinal cord, brain stem, and motor cortex. |
2022-06-19 |
2023-08-14 |
human |
| Masaaki Yoshikawa, Chihiro Ishikawa, Haiyan Li, Takashi Kudo, Dai Shiba, Masaki Shirakawa, Masafumi Murtani, Satoru Takahashi, Shin Aizawa, Takashi Shig. Comparing effects of microgravity and amyotrophic lateral sclerosis in the mouse ventral lumbar spinal cord. Molecular and cellular neurosciences. 2022-06-06. PMID:35660087. |
comparing effects of microgravity and amyotrophic lateral sclerosis in the mouse ventral lumbar spinal cord. |
2022-06-06 |
2023-08-14 |
mouse |
| Shun Mitsui, Asako Otomo, Kai Sato, Masahito Ishiyama, Kento Shimakura, Chisa Okada-Yamaguchi, Eiji Warabi, Toru Yanagawa, Masashi Aoki, Hui-Fang Shang, Shinji Hadan. SQSTM1, a protective factor of SOD1-linked motor neuron disease, regulates the accumulation and distribution of ubiquitinated protein aggregates in neuron. Neurochemistry international. 2022-05-31. PMID:35640762. |
amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease characterized by selective loss of motor neurons in the brain and spinal cord. |
2022-05-31 |
2023-08-13 |
mouse |
| George Padilla, James Shorter, Jack Rubie. Exploring the Effect of RNA Binding on TDP-43 Liquid-Liquid Phase Separation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554166. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease that is characterized by progressive deterioration of nerve cells in the brain and spinal cord. |
2022-05-13 |
2023-08-13 |
Not clear |
| Shanshan Wang, Taiga Ichinomiya, Brian Hea. AAV9-synapsin-caveolin-1 (AAV9-SynCav1) gene delivery preserves motor neuron and neuromuscular junction morphology, motor function and body weight, and extends survival in hSOD1 FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35557138. |
aav9-synapsin-caveolin-1 (aav9-syncav1) gene delivery preserves motor neuron and neuromuscular junction morphology, motor function and body weight, and extends survival in hsod1 amyotrophic lateral sclerosis (als) is a neurodegenerative disease resulting from loss of upper and lower motor neurons in the brain and spinal cord. |
2022-05-13 |
2023-08-13 |
mouse |
| Santimoy Sen, Sheetal Lagas, Abhishek Roy, Hemant Kuma. Cytoskeleton saga: Its regulation in normal physiology and modulation in neurodegenerative disorders. European journal of pharmacology. 2022-05-07. PMID:35525310. |
disruption of this organization due to faulty genetics, oxidative stress or impaired transport mechanisms are the major causes of dysregulated signalling cascades leading to various pathological conditions like alzheimer's (ad), parkinson's (pd), huntington's disease (hd) or amyotrophic lateral sclerosis (als), hereditary spastic paraplegia (hsp) or any traumatic injury like spinal cord injury (sci). |
2022-05-07 |
2023-08-13 |
Not clear |
| Vivek Pai, Chintan R Trivedi, Bhujang Pai, Saravana K Swaminatha. T1 hyperintensity in the spinal cord: A diagnostic marker of amyotrophic lateral sclerosis? Journal of clinical imaging science. vol 12. 2022-05-05. PMID:35510239. |
t1 hyperintensity in the spinal cord: a diagnostic marker of amyotrophic lateral sclerosis? |
2022-05-05 |
2023-08-13 |
Not clear |
| Benjamin G Trist, Sian Genoud, Stéphane Roudeau, Alexander Rookyard, Amr Abdeen, Veronica Cottam, Dominic J Hare, Melanie White, Jens Altvater, Jennifer A Fifita, Alison Hogan, Natalie Grima, Ian P Blair, Kai Kysenius, Peter J Crouch, Asuncion Carmona, Yann Rufin, Stéphane Claverol, Stijn Van Malderen, Gerald Falkenberg, David J Paterson, Bradley Smith, Claire Troakes, Caroline Vance, Christopher E Shaw, Safa Al-Sarraj, Stuart Cordwell, Glenda Halliday, Richard Ortega, Kay L Doubl. Altered SOD1 maturation and post-translational modification in amyotrophic lateral sclerosis spinal cord. Brain : a journal of neurology. 2022-05-05. PMID:35512359. |
altered sod1 maturation and post-translational modification in amyotrophic lateral sclerosis spinal cord. |
2022-05-05 |
2023-08-13 |
Not clear |