| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guanghao Liu, Milan Fiala, Mathew T Mizwicki, James Sayre, Larry Magpantay, Avi Siani, Michelle Mahanian, Madhuri Chattopadhyay, Antonio La Cava, Martina Wiedau-Pazo. Neuronal phagocytosis by inflammatory macrophages in ALS spinal cord: inhibition of inflammation by resolvin D1. American journal of neurodegenerative disease. vol 1. issue 1. 2021-10-21. PMID:22787561. |
although the cause of neuronal degeneration in amyotrophic lateral sclerosis (als) remains hypothetical, there is evidence of spinal cord infiltration by macrophages and t cells. |
2021-10-21 |
2023-08-12 |
Not clear |
| Paul A Lapcha. Scientific Rigor Recommendations for Optimizing the Clinical Applicability of Translational Research. Journal of neurology & neurophysiology. vol 3. 2021-10-21. PMID:24490120. |
this article describes in detail a set of recommendations to improve the quality of science being conducted in laboratories worldwide, with the goal of documenting in the peer-reviewed literature, including journal of neurology and neurophysiology, the scientific basis for the continued development of specific strategies to treat neurodegenerative diseases such as stroke, alzheimer's disease, huntington's disease, parkinson's disease, spinal cord injury, and amyotrophic lateral sclerosis. |
2021-10-21 |
2023-08-12 |
Not clear |
| Toru Yamashita, Yoshihiro Kushida, Koji Abe, Mari Dezaw. Non-Tumorigenic Pluripotent Reparative Muse Cells Provide a New Therapeutic Approach for Neurologic Diseases. Cells. vol 10. issue 4. 2021-10-20. PMID:33924240. |
owing to these unique characteristics, clinical trials using intravenously administered donor-muse cells have been conducted for myocardial infarction, stroke, epidermolysis bullosa, spinal cord injury, perinatal hypoxic ischemic encephalopathy, and amyotrophic lateral sclerosis. |
2021-10-20 |
2023-08-13 |
Not clear |
| Neepa Gurbani, John E Pascoe, Sherri Katz, Hemant Sawnan. Sleep disordered breathing: Assessment and therapy in the age of emerging neuromuscular therapies. Pediatric pulmonology. vol 56. issue 4. 2021-10-12. PMID:32720756. |
although it may be conventional to relate the use of this term to the most common muscular diseases (duchenne muscular dystrophy [dmd], spinal muscular atrophy [sma], and amyotrophic lateral sclerosis, etc), it is important to extend the term to pathologies manifested by severe neurologic (brain and spinal cord) malformations and injuries. |
2021-10-12 |
2023-08-13 |
Not clear |
| Hee Ra Park, Eun Jin Yan. Oxidative Stress as a Therapeutic Target in Amyotrophic Lateral Sclerosis: Opportunities and Limitations. Diagnostics (Basel, Switzerland). vol 11. issue 9. 2021-10-01. PMID:34573888. |
amyotrophic lateral sclerosis (als), also known as motor neuron disease (mnd) and lou gehrig's disease, is characterized by a loss of the lower motor neurons in the spinal cord and the upper motor neurons in the cerebral cortex. |
2021-10-01 |
2023-08-13 |
Not clear |
| Yui Kobatake, Kohei Nakata, Hiroki Sakai, Jun Sasaki, Osamu Yamato, Satoshi Takashima, Naohito Nishii, Sadatoshi Maeda, Md Shafiqul Islam, Hiroaki Kamishin. The Long-Term Clinical Course of Canine Degenerative Myelopathy and Therapeutic Potential of Curcumin. Veterinary sciences. vol 8. issue 9. 2021-09-30. PMID:34564586. |
canine degenerative myelopathy (dm), recognized as a spontaneous model of amyotrophic lateral sclerosis, is known as a late-onset progressive degenerative disease of the spinal cord. |
2021-09-30 |
2023-08-13 |
dog |
| Meena S Subbarayan, Aurelie Joly-Amado, Paula C Bickford, Kevin R Nas. CX3CL1/CX3CR1 signaling targets for the treatment of neurodegenerative diseases. Pharmacology & therapeutics. 2021-09-24. PMID:34492237. |
the role of cx3cl1/cxcr1 is reviewed in the context of alzheimer's disease (ad), parkinson's disease (pd), huntington's disease (hd), ischemia, retinopathies, spinal cord and neuropathic pain, traumatic brain injury, amyotrophic lateral sclerosis, multiple sclerosis, and epilepsy. |
2021-09-24 |
2023-08-13 |
Not clear |
| Yueh-Lin Tsai, James L Manle. Multiple ways to a dead end: diverse mechanisms by which ALS mutant genes induce cell death. Cell cycle (Georgetown, Tex.). vol 20. issue 7. 2021-09-23. PMID:33722167. |
amyotrophic lateral sclerosis (als) is a deadly neuromuscular disorder caused by progressive motor neuron loss in the brain and spinal cord. |
2021-09-23 |
2023-08-13 |
Not clear |
| b' Dilek \\xc4\\xb0\\xc5\\x9fcan, Muhammet Bu\\xc4\\x9fra Karaaslan, Onur Sinan Deveci, Rabia Ak\\xc4\\xb1ll\\xc4\\xb1 Eker, Filiz Ko\\xc3\\xa. The importance of heart rate variability in predicting cardiac autonomic dysfunction in patients with amyotrophic lateral sclerosis. International journal of clinical practice. vol 75. issue 10. 2021-09-21. PMID:34132003.' |
amyotrophic lateral sclerosis (als) is a progressive disease characterized by degeneration in the upper and lower motor neurons of the corticospinal tract, brain stem, and spinal cord. |
2021-09-21 |
2023-08-13 |
Not clear |
| b' Pavl\\xc3\\xadna Hemerkov\\xc3\\xa1, Martin Vali\\xc5\\xa. Role of Oxidative Stress in the Pathogenesis of Amyotrophic Lateral Sclerosis: Antioxidant Metalloenzymes and Therapeutic Strategies. Biomolecules. vol 11. issue 3. 2021-09-15. PMID:33809730.' |
amyotrophic lateral sclerosis (als) affects motor neurons in the cerebral cortex, brainstem and spinal cord and leads to death due to respiratory failure within three to five years. |
2021-09-15 |
2023-08-13 |
Not clear |
| Sahara J Cathcart, Stanley H Appel, Leif E Peterson, Ericka P Greene, Suzanne Z Powell, Anithachristy S Arumanayagam, Andreana L Rivera, Matthew D Cykowsk. Fast Progression in Amyotrophic Lateral Sclerosis Is Associated With Greater TDP-43 Burden in Spinal Cord. Journal of neuropathology and experimental neurology. vol 80. issue 8. 2021-09-15. PMID:34383907. |
fast progression in amyotrophic lateral sclerosis is associated with greater tdp-43 burden in spinal cord. |
2021-09-15 |
2023-08-13 |
Not clear |
| Merav Cohen, Amir Giladi, Catarina Raposo, Mor Zada, Baoguo Li, Julia Ruckh, Aleksandra Deczkowska, Boaz Mohar, Ravid Shechter, Rachel G Lichtenstein, Ido Amit, Michal Schwart. Meningeal lymphoid structures are activated under acute and chronic spinal cord pathologies. Life science alliance. vol 4. issue 1. 2021-09-14. PMID:33277355. |
using a chronic model of spinal cord pathology, the msod1 mouse model of amyotrophic lateral sclerosis, we further showed by single-cell rna-sequencing that a meningeal lymphocyte niche forms, with a unique organization and activation state, including accumulation of pre-b cells in the spinal cord meninges. |
2021-09-14 |
2023-08-13 |
mouse |
| A V Alessenko, U A Gutner, V O Nebogatikov, M A Shupik, A A Ustyugo. [The role of sphingolipids in pathogenesis of amyotrophic lateral sclerosis]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 121. issue 8. 2021-09-07. PMID:34481449. |
amyotrophic lateral sclerosis (als) is an incurable neurodegenerative disease characterized by selective degeneration of motor neurons of the spinal cord and motor cortex and brain stem. |
2021-09-07 |
2023-08-13 |
Not clear |
| Chad Bouton, Nikunj Bhagat, Santosh Chandrasekaran, Jose Herrero, Noah Markowitz, Elizabeth Espinal, Joo-Won Kim, Richard Ramdeo, Junqian Xu, Matthew F Glasser, Stephan Bickel, Ashesh Meht. Decoding Neural Activity in Sulcal and White Matter Areas of the Brain to Accurately Predict Individual Finger Movement and Tactile Stimuli of the Human Hand. Frontiers in neuroscience. vol 15. 2021-09-07. PMID:34483823. |
millions of people worldwide suffer motor or sensory impairment due to stroke, spinal cord injury, multiple sclerosis, traumatic brain injury, diabetes, and motor neuron diseases such as als (amyotrophic lateral sclerosis). |
2021-09-07 |
2023-08-13 |
human |
| Surinder Pal, Abha Tiwari, Kaushal Sharma, Suresh Kumar Sharm. Does conserved domain SOD1 mutation has any role in ALS severity and therapeutic outcome? BMC neuroscience. vol 21. issue 1. 2021-09-02. PMID:33036560. |
amyotrophic lateral sclerosis (als) is a progressive neurodegenerative fatal disease that can affect the neurons of brain and spinal cord. |
2021-09-02 |
2023-08-13 |
Not clear |
| Nikol Jankovska, Radoslav Mate. Molecular Pathology of ALS: What We Currently Know and What Important Information Is Still Missing. Diagnostics (Basel, Switzerland). vol 11. issue 8. 2021-08-30. PMID:34441299. |
despite an early understanding of amyotrophic lateral sclerosis (als) as a disease affecting the motor system, including motoneurons in the motor cortex, brainstem, and spinal cord, today, many cases involving dementia and behavioral disorders are reported. |
2021-08-30 |
2023-08-13 |
Not clear |
| Rita F Marques, Jan B Engler, Katrin Küchler, Ross A Jones, Thomas Lingner, Gabriela Salinas, Thomas H Gillingwater, Manuel A Friese, Kent E Dunca. Motor neuron translatome reveals deregulation of SYNGR4 and PLEKHB1 in mutant TDP-43 amyotrophic lateral sclerosis models. Human molecular genetics. vol 29. issue 16. 2021-08-27. PMID:32686835. |
amyotrophic lateral sclerosis (als) is an incurable neurological disease with progressive loss of motor neuron (mn) function in the brain and spinal cord. |
2021-08-27 |
2023-08-13 |
mouse |
| A Bakiya, K Kamalanand, V Rajinikant. Automated diagnosis of amyotrophic lateral sclerosis using electromyograms and firefly algorithm based neural networks with fractional position update. Physical and engineering sciences in medicine. 2021-08-16. PMID:34398392. |
amyotrophic lateral sclerosis (als) is a disorder of the neuromuscular system that causes the impairment of nerve cells from brain to spinal cord and to the voluntary muscles in every part of the human physiological system, which totally leads to paralysis. |
2021-08-16 |
2023-08-13 |
human |
| Hirotoshi Magota, Masanori Sasaki, Yuko Kataoka-Sasaki, Shinichi Oka, Ryo Ukai, Ryo Kiyose, Rie Onodera, Jeffery D Kocsis, Osamu Honmo. Repeated infusion of mesenchymal stem cells maintain the condition to inhibit deteriorated motor function, leading to an extended lifespan in the SOD1G93A rat model of amyotrophic lateral sclerosis. Molecular brain. vol 14. issue 1. 2021-08-12. PMID:33962678. |
amyotrophic lateral sclerosis (als) is a neurodegenerative fatal disorder in which motor neurons within the brain and spinal cord degenerate. |
2021-08-12 |
2023-08-13 |
rat |
| Mahboobeh Ghasemzadeh Rahbardar, Hossein Hosseinzade. Effects of rosmarinic acid on nervous system disorders: an updated review. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 10. 2021-08-11. PMID:32725282. |
in this regard, we classified and discussed our findings in different nervous system disorders including alzheimer's disease, epilepsy, depression, huntington's disease, familial amyotrophic lateral sclerosis, parkinson's disease, cerebral ischemia/reperfusion injury, spinal cord injury, stress, anxiety, and pain. |
2021-08-11 |
2023-08-13 |
Not clear |