| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ali Shojaie, Ahmad Al Khleifat, Sarah Garrahy, Haniah Habash-Bailey, Rachel Thomson, Sarah Opie-Martin, Sara Javidnia, P Nigel Leigh, Ammar Al-Chalab. Investigating the impact of socioeconomic status on amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis & frontotemporal degeneration. 2024-09-01. PMID:39218010. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by the gradual death of motor neurons in the brain and spinal cord, leading to fatal paralysis. |
2024-09-01 |
2024-09-04 |
human |
| Payam Dibaj, Sam Safavi-Abbasi, Ebrahim Asadollah. In vivo spectrally unmixed multi-photon imaging of longitudinal axon-glia changes in injured spinal white matter. Neuroscience letters. 2024-09-01. PMID:39218293. |
understanding the sequence of cellular responses and their contributions to pathomorphogical changes in spinal white matter injuries is a prerequisite for developing efficient therapeutic strategies for spinal cord injury (sci) as well as neurodegenerative and inflammatory diseases of the spinal cord such as amyotrophic lateral sclerosis and multiple sclerosis. |
2024-09-01 |
2024-09-04 |
mouse |
| Brigid K Jense. Astrocyte-Neuron Interactions Contributing to Amyotrophic Lateral Sclerosis Progression. Advances in neurobiology. vol 39. 2024-08-27. PMID:39190080. |
amyotrophic lateral sclerosis (als) is a complex disease impacting motor neurons of the brain, brainstem, and spinal cord. |
2024-08-27 |
2024-08-30 |
Not clear |
| Zihao Liu, Huan Zhang, Kaili Lu, Li Chen, Yueqi Zhang, Zhouwei Xu, Hongsheng Zhou, Junfeng Sun, Mengyang Xu, Qi Ouyang, Garth J Thompson, Yi Yang, Ni Su, Xiaojun Cai, Li Cao, Yuwu Zhao, Lixian Jiang, Yuanyi Zheng, Xiaojie Zhan. Low-intensity pulsed ultrasound modulates disease progression in the SOD1 Cell reports. vol 43. issue 9. 2024-08-24. PMID:39180748. |
low-intensity pulsed ultrasound modulates disease progression in the sod1 amyotrophic lateral sclerosis (als) is a devastating neurodegenerative disease characterized by the progressive loss of motor neurons in the brain and spinal cord, and there are no effective drug treatments. |
2024-08-24 |
2024-08-27 |
Not clear |
| Mohsen Farhangian, Forouzan Azarafrouz, Neda Valian, Leila Dargah. The role of interferon beta in neurological diseases and its potential therapeutic relevance. European journal of pharmacology. 2024-08-11. PMID:39128808. |
then we will focus on the potential role and therapeutic effect of ifnβ in several cns-related diseases such as alzheimer's disease, parkinson's disease, huntington's disease, amyotrophic lateral sclerosis, stroke, spinal cord injury, prion disease and spinocerebellar ataxia 7. |
2024-08-11 |
2024-08-14 |
Not clear |
| Liam M Koehn, Roshan Jalaldeen, Joseph Pelle, Joseph A Nicolazz. Plasma, brain and spinal cord concentrations of caffeine are reduced in the SOD1 European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2024-08-04. PMID:39098618. |
plasma, brain and spinal cord concentrations of caffeine are reduced in the sod1 modifications to the small intestine and liver are known to occur during the symptomatic disease period of amyotrophic lateral sclerosis (als), a member of the motor neuron disease (mnd) family of neurodegenerative disorders. |
2024-08-04 |
2024-08-07 |
Not clear |
| Maria Guarnaccia, Giovanna Morello, Valentina La Cognata, Vincenzo La Bella, Francesca Luisa Conforti, Sebastiano Cavallar. Increased copy-number variant load of associated risk genes in sporadic cases of amyotrophic lateral sclerosis. Cellular and molecular life sciences : CMLS. vol 81. issue 1. 2024-07-28. PMID:39066921. |
amyotrophic lateral sclerosis (als) is an age-related neurodegenerative disease characterized by selective loss of motor neurons in the brainstem and spinal cord. |
2024-07-28 |
2024-08-02 |
Not clear |
| Ramyar Rahimi Darehbagh, Seyedeh Asrin Seyedoshohadaei, Rojin Ramezani, Nima Rezae. Stem cell therapies for neurological disorders: current progress, challenges, and future perspectives. European journal of medical research. vol 29. issue 1. 2024-07-26. PMID:39054501. |
this comprehensive review provides an in-depth analysis of the current state of stem cell applications in primary neurological conditions, including parkinson's disease (pd), alzheimer's disease (ad), amyotrophic lateral sclerosis (als), multiple sclerosis (ms), stroke, spinal cord injury (sci), and other related disorders. |
2024-07-26 |
2024-07-28 |
human |
| Angela Corvino, Giuseppe Caliendo, Ferdinando Fiorino, Francesco Frecentese, Valeria Valsecchi, Giovanna Lombardi, Serenella Anzilotti, Giorgia Andreozzi, Antonia Scognamiglio, Rosa Sparaco, Elisa Perissutti, Beatrice Severino, Michele Gargiulo, Vincenzo Santagada, Giuseppe Pignatar. Newly Synthesized Indolylacetic Derivatives Reduce Tumor Necrosis Factor-Mediated Neuroinflammation and Prolong Survival in Amyotrophic Lateral Sclerosis Mice. ACS pharmacology & translational science. vol 7. issue 7. 2024-07-18. PMID:39022351. |
the debilitating neurodegenerative disease known as amyotrophic lateral sclerosis (als) is characterized by the progressive loss of motor neurons (mns) in the brain, spinal cord, and motor cortex. |
2024-07-18 |
2024-07-20 |
mouse |
| Ermanna Turano, Federica Virla, Ilaria Scambi, Sylwia Dabrowska, Oluwamolakun Bankole, Raffaella Mariott. Adipose mesenchymal stem cells-derived extracellular vesicles exert their preferential action in damaged central sites of SOD1 mice rather than peripherally. European journal of histochemistry : EJH. vol 68. issue 3. 2024-07-04. PMID:38963135. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disorder involving motor neuron (mn) loss in the motor cortex, brainstem and spinal cord leading to progressive paralysis and death. |
2024-07-04 |
2024-07-10 |
mouse |
| Elisabetta Carata, Marco Muci, Stefania Mariano, Simona Di Giulio, Annamaria Nigro, Alessandro Romano, Elisa Panzarin. Extracellular Vesicles from NSC-34 MN-like Cells Transfected with Mutant SOD1 Modulate Inflammatory Status of Raw 264.7 Macrophages. Genes. vol 15. issue 6. 2024-06-27. PMID:38927671. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease targeting the brain and spinal cord. |
2024-06-27 |
2024-06-29 |
Not clear |
| Ching-Yi Lin, Veronica Vanoverbeke, David Trent, Kathryn Willey, Yu-Shang Le. The Spatiotemporal Expression of SOCS3 in the Brainstem and Spinal Cord of Amyotrophic Lateral Sclerosis Mice. Brain sciences. vol 14. issue 6. 2024-06-27. PMID:38928564. |
the spatiotemporal expression of socs3 in the brainstem and spinal cord of amyotrophic lateral sclerosis mice. |
2024-06-27 |
2024-06-29 |
mouse |
| Ching-Yi Lin, Veronica Vanoverbeke, David Trent, Kathryn Willey, Yu-Shang Le. The Spatiotemporal Expression of SOCS3 in the Brainstem and Spinal Cord of Amyotrophic Lateral Sclerosis Mice. Brain sciences. vol 14. issue 6. 2024-06-27. PMID:38928564. |
amyotrophic lateral sclerosis (als) is characterized by the progressive loss of motor neurons from the brain and spinal cord. |
2024-06-27 |
2024-06-29 |
mouse |
| Zoë Donders, Iga Joanna Skorupska, Emily Willems, Femke Mussen, Jana Van Broeckhoven, Aurélie Carlier, Melissa Schepers, Tim Vanmierl. Beyond PDE4 inhibition: A comprehensive review on downstream cAMP signaling in the central nervous system. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 177. 2024-06-22. PMID:38908196. |
thus, elevating camp levels through pde inhibition provides a therapeutic approach for multiple cns disorders, including multiple sclerosis, stroke, spinal cord injury, amyotrophic lateral sclerosis, traumatic brain injury, and alzheimer's disease. |
2024-06-22 |
2024-06-25 |
Not clear |
| Marlene Tahedl, Ee Ling Tan, Jana Kleinerova, Siobhan Delaney, Jennifer C Hengeveld, Mark A Doherty, Russell L Mclaughlin, Pierre-Francois Pradat, Cédric Raoul, Fabrice Ango, Orla Hardiman, Kai Ming Chang, Jasmin Lope, Peter Bed. Progressive Cerebrocerebellar Uncoupling in Sporadic and Genetic Forms of Amyotrophic Lateral Sclerosis. Neurology. vol 103. issue 2. 2024-06-20. PMID:38900989. |
amyotrophic lateral sclerosis (als) is predominantly associated with motor cortex, corticospinal tract (cst), brainstem, and spinal cord degeneration, and cerebellar involvement is much less well characterized. |
2024-06-20 |
2024-06-23 |
Not clear |
| Sylwia Dabrowska, Ermanna Turano, Ilaria Scambi, Federica Virla, Alice Nodari, Francesco Pezzini, Mirco Galiè, Bruno Bonetti, Raffaella Mariott. A Cellular Model of Amyotrophic Lateral Sclerosis to Study the Therapeutic Effects of Extracellular Vesicles from Adipose Mesenchymal Stem Cells on Microglial Activation. International journal of molecular sciences. vol 25. issue 11. 2024-06-19. PMID:38891895. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by the progressive degeneration of upper and lower motor neurons (mns) in the brain and spinal cord, leading to progressive paralysis and death. |
2024-06-19 |
2024-06-21 |
human |
| Steven P Brow. Diagnosis of Cervical Spinal Cord Multiple Sclerosis by a Chiropractic Physician: A Case Report. Cureus. vol 16. issue 6. 2024-06-19. PMID:38894936. |
the differential diagnosis included lower cervical spine nerve root compression or neurological disorders such as amyotrophic lateral sclerosis, cerebral lesion, motor neuropathy, multiple sclerosis, or spinal cord lesion. |
2024-06-19 |
2024-06-21 |
Not clear |
| Brenda Murage, Han Tan, Tomoji Mashimo, Mandy Jackson, Paul A Skehe. Spinal cord neurone loss and foot placement changes in a rat knock-in model of amyotrophic lateral sclerosis Type 8. Brain communications. vol 6. issue 3. 2024-06-08. PMID:38846532. |
spinal cord neurone loss and foot placement changes in a rat knock-in model of amyotrophic lateral sclerosis type 8. |
2024-06-08 |
2024-06-10 |
rat |
| Seán C Ó Murchú, Ken D O'Hallora. BREATHE DMD: boosting respiratory efficacy after therapeutic hypoxic episodes in Duchenne muscular dystrophy. The Journal of physiology. 2024-06-05. PMID:38837229. |
various paradigms of intermittent hypoxia have been designed and implemented in human trials culminating in clinical trials in people with spinal cord injury and amyotrophic lateral sclerosis. |
2024-06-05 |
2024-06-08 |
human |
| Xingyuan Chen, Zhongwen Cao, Yinsheng Wan. Amyotrophic Lateral Sclerosis-Associated Mutants of SOD1 Perturb mRNA Splicing through Aberrant Interactions with SRSF2. Analytical chemistry. 2024-05-25. PMID:38795036. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disorder that results in the degeneration of neurons in the brain and spinal cord. |
2024-05-25 |
2024-05-27 |
human |