| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rebecca Stevenson, Evgeniia Samokhina, Armaan Mangat, Ilaria Rossetti, Sushmitha S Purushotham, Chandra S Malladi, John W Morley, Yossi Buskil. Astrocytic K Glia. 2023-07-03. PMID:37395323. |
astrocytic k amyotrophic lateral sclerosis (als) is a neurodegenerative disorder in which patients lose motor functions due to progressive loss of motor neurons in the cortex, brainstem, and spinal cord. |
2023-07-03 |
2023-08-14 |
Not clear |
| Quyen Thi Nguyen, Liem Nguyen Thanh, Van T Hoang, Trang T K Phan, Michael Heke, Duc M Hoan. Bone Marrow-Derived Mononuclear Cells in the Treatment of Neurological Diseases: Knowns and Unknowns. Cellular and molecular neurobiology. 2023-06-25. PMID:37356043. |
in this review, we discuss known and unknown aspects of bmmncs, including the cell harvesting, administration route and dose; mechanisms of action; and their applications in neurological diseases, including stroke, cerebral palsy, spinal cord injury, traumatic brain injury, amyotrophic lateral sclerosis, autism spectrum disorder, and epilepsy. |
2023-06-25 |
2023-08-14 |
Not clear |
| Brian M Balog, Anisha Sonti, Richard E Zigmon. Neutrophil Biology in Injuries and Diseases of the Central and Peripheral Nervous Systems. Progress in neurobiology. 2023-06-24. PMID:37355220. |
we then turn to a review of what is known about the role of neutrophils in cns and pns diseases and injury, including stroke, alzheimer's disease, multiple sclerosis, amyotrophic lateral sclerosis, spinal cord and traumatic brain injuries, cns and pns axon regeneration, and neuropathic pain. |
2023-06-24 |
2023-08-14 |
Not clear |
| Nomakhosazana R Monnakgotla, Amokelani C Mahungu, Jeannine M Heckmann, Gerrit Botha, Nicola J Mulder, Gang Wu, Evadnie Rampersaud, Jason Myers, Marka Van Blitterswijk, Rosa Rademakers, J Paul Taylor, Joanne Wuu, Michael Benatar, Melissa Ne. Analysis of Structural Variants Previously Associated With ALS in Europeans Highlights Genomic Architectural Differences in Africans. Neurology. Genetics. vol 9. issue 4. 2023-06-22. PMID:37346932. |
amyotrophic lateral sclerosis (als) is a degenerative condition of the brain and spinal cord in which protein-coding variants in known als disease genes explain a minority of sporadic cases. |
2023-06-22 |
2023-08-14 |
Not clear |
| Amanda J Guise, Santosh A Misal, Richard Carson, Hannah Boekweg, Daisha Van Der Watt, Thy Truong, Yiran Liang, Jen-Hwa Chu, Nora C Welsh, Jake Gagnon, Samuel H Payne, Edward D Plowey, Ryan T Kell. TDP-43-stratified single-cell proteomic profiling of postmortem human spinal motor neurons reveals protein dynamics in amyotrophic lateral sclerosis. bioRxiv : the preprint server for biology. 2023-06-19. PMID:37333094. |
unbiased proteomics has been employed to interrogate central nervous system (cns) tissues (brain, spinal cord) and fluid matrices (csf, plasma) from amyotrophic lateral sclerosis (als) patients; yet, a limitation of conventional bulk tissue studies is that motor neuron (mn) proteome signals may be confounded by admixed non-mn proteins. |
2023-06-19 |
2023-08-14 |
human |
| Pramod Kumar Pisharady, Lynn E Eberly, Isaac M Adanyeguh, Georgios Manousakis, Gaurav Guliani, David Walk, Christophe Lengle. Multimodal MRI improves diagnostic accuracy and sensitivity to longitudinal change in amyotrophic lateral sclerosis. Communications medicine. vol 3. issue 1. 2023-06-16. PMID:37328685. |
in this work, we aim to demonstrate increased sensitivity to disease progression as well as improved diagnostic accuracy in amyotrophic lateral sclerosis (als) with multimodal mri of the brain and cervical spinal cord. |
2023-06-16 |
2023-08-14 |
Not clear |
| Michael N Maxwell, Anthony L Marullo, Aoife D Slyne, Eric F Lucking, Ken D O'Hallora. Ventilatory Effects of Acute Intermittent Hypoxia in Conscious Dystrophic Mice. Advances in experimental medicine and biology. vol 1427. 2023-06-15. PMID:37322338. |
interest has grown in developing aih interventions to treat ventilatory insufficiency, with promising results in spinal cord injury and amyotrophic lateral sclerosis. |
2023-06-15 |
2023-08-14 |
mouse |
| Erica Tavazzi, Enrico Longato, Martina Vettoretti, Helena Aidos, Isotta Trescato, Chiara Roversi, Andreia S Martins, Eduardo N Castanho, Ruben Branco, Diogo F Soares, Alessandro Guazzo, Giovanni Birolo, Daniele Pala, Pietro Bosoni, Adriano Chiò, Umberto Manera, Mamede de Carvalho, Bruno Miranda, Marta Gromicho, Inês Alves, Riccardo Bellazzi, Arianna Dagliati, Piero Fariselli, Sara C Madeira, Barbara Di Camill. Artificial intelligence and statistical methods for stratification and prediction of progression in amyotrophic lateral sclerosis: A systematic review. Artificial intelligence in medicine. vol 142. 2023-06-14. PMID:37316101. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disorder characterised by the progressive loss of motor neurons in the brain and spinal cord. |
2023-06-14 |
2023-08-14 |
Not clear |
| Satoshi Yamashita, Nozomu Tawara, Kentaro Hara, Mitsuharu Ued. Gender differences in clinical features at the initial examination of late-onset amyotrophic lateral sclerosis. Journal of the neurological sciences. vol 451. 2023-06-09. PMID:37295193. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease that mainly affects motor neurons in the brain and spinal cord. |
2023-06-09 |
2023-08-14 |
Not clear |
| Noelle C Punessen, Claudia Pena, Alexandra Sandberg, Lilia A Koza, Daniel A Linsema. A novel anti-apoptotic role for Cdc42/ACK-1 signaling in neurons. Molecular and cellular neurosciences. 2023-06-01. PMID:37263460. |
neurodegenerative diseases such as amyotrophic lateral sclerosis, alzheimer's and parkinson's disease are caused by a progressive and aberrant destruction of neurons in the brain and spinal cord. |
2023-06-01 |
2023-08-14 |
rat |
| Hui Wang, LiPing Guan, Min Den. Recent progress of the genetics of amyotrophic lateral sclerosis and challenges of gene therapy. Frontiers in neuroscience. vol 17. 2023-05-30. PMID:37250416. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disorder characterized by the degeneration of motor neurons in the brain and spinal cord. |
2023-05-30 |
2023-08-14 |
Not clear |
| Mohamed F Elmansy, Cory T Reidl, Mizzanoor Rahaman, P Hande Özdinler, Richard B Silverma. Small molecules targeting different cellular pathologies for the treatment of amyotrophic lateral sclerosis. Medicinal research reviews. 2023-05-27. PMID:37243319. |
amyotrophic lateral sclerosis (als) is a devastating neurodegenerative disease in which the motor neuron circuitry displays progressive degeneration, affecting mostly the motor neurons in the brain and in the spinal cord. |
2023-05-27 |
2023-08-14 |
Not clear |
| Laura López-Pingarrón, Henrique Almeida, Marisol Soria-Aznar, Marcos C Reyes-Gonzales, María Pilar Terrón, Joaquín J Garcí. Role of Oxidative Stress on the Etiology and Pathophysiology of Amyotrophic Lateral Sclerosis (ALS) and Its Relation with the Enteric Nervous System. Current issues in molecular biology. vol 45. issue 4. 2023-05-16. PMID:37185741. |
amyotrophic lateral sclerosis (als) is a progressive neurodegenerative disease affecting motor neurons in the spinal cord, cerebral cortex, and medulla oblongata. |
2023-05-16 |
2023-08-14 |
Not clear |
| Yinrou Huang, Mengke Zhao, Xuemei Chen, Ruoyu Zhang, Anh Le, Michael Hong, Yufei Zhang, Lin Jia, Weidong Zang, Chao Jiang, Junmin Wang, Xiaochong Fan, Jian Wan. Tryptophan Metabolism in Central Nervous System Diseases: Pathophysiology and Potential Therapeutic Strategies. Aging and disease. vol 14. issue 3. 2023-05-16. PMID:37191427. |
in this review, we summarize the biological properties of key metabolites and their pathogenic functions in 12 disorders of the central nervous system: schizophrenia, bipolar disorder, major depressive disorder, spinal cord injury, traumatic brain injury, ischemic stroke, intracerebral hemorrhage, multiple sclerosis, alzheimer's disease, parkinson's disease, amyotrophic lateral sclerosis, and huntington's disease. |
2023-05-16 |
2023-08-14 |
Not clear |
| Bárbara Teruel-Peña, José Luís Gómez-Urquiza, Nora Suleiman-Martos, Isabel Prieto, Francisco José García-Cózar, Manuel Ramírez-Sánchez, Carmen Fernández-Martos, Germán Domínguez-Vía. Systematic Review and Meta-Analyses of Aminopeptidases as Prognostic Biomarkers in Amyotrophic Lateral Sclerosis. International journal of molecular sciences. vol 24. issue 8. 2023-04-28. PMID:37108335. |
amyotrophic lateral sclerosis (als) is a fatal neurodegenerative disease characterized by the progressive loss of motor neurons in the spinal cord, brain stem, and cerebral cortex. |
2023-04-28 |
2023-08-14 |
human |
| Christopher Q Rogers, Melissa Ramirez, Carol S Landon, Janine M DeBlasi, Andrew P Koutnik, Csilla Ari, Dominic P D'Agostin. A Glutamate Scavenging Protocol Combined with Deanna Protocol in SOD1-G93A Mouse Model of ALS. Nutrients. vol 15. issue 8. 2023-04-28. PMID:37111040. |
amyotrophic lateral sclerosis (als) is a progressive disease of neuronal degeneration in the motor cortex, brainstem, and spinal cord, resulting in impaired motor function and premature demise as a result of insufficient respiratory drive. |
2023-04-28 |
2023-08-14 |
mouse |
| Michael Punsoni, Nelli S Lakis, Michelle Mellion, Suzanne M de la Mont. Post-Polio Syndrome Revisited. Neurology international. vol 15. issue 2. 2023-04-24. PMID:37092507. |
pps afflicts between 25% and 40% of poliomyelitis survivors and mimics motor neuron diseases (mnds), such as amyotrophic lateral sclerosis (als), due to its selective impairment, degeneration, or death of motor neurons in the brainstem and spinal cord. |
2023-04-24 |
2023-08-14 |
Not clear |
| Ling Cao, Elizabeth N Bean, Jennifer T Malo. Preparation of Primary Mixed Glial Cell Cultures from Adult Mouse Spinal Cord Tissue. Current protocols. vol 3. issue 4. 2023-04-12. PMID:37042635. |
mixed glial cultures can be prepared from animals of different strains or post-in vivo manipulations and therefore are suitable for studying a variety of diseases/disorders that involve spinal cord pathological changes, such as amyotrophic lateral sclerosis and multiple sclerosis, as well as toxin-induced changes. |
2023-04-12 |
2023-08-14 |
mouse |
| He Jax Xu, Yao Yao, Fenyong Yao, Jiehui Chen, Meishi Li, Xianfa Yang, Sheng Li, Fangru Lu, Ping Hu, Shuijin He, Guangdun Peng, Naihe Jin. Generation of functional posterior spinal motor neurons from hPSCs-derived human spinal cord neural progenitor cells. Cell regeneration (London, England). vol 12. issue 1. 2023-03-23. PMID:36949352. |
spinal motor neurons deficiency results in a series of devastating disorders such as amyotrophic lateral sclerosis (als), spinal muscular atrophy (sma) and spinal cord injury (sci). |
2023-03-23 |
2023-08-14 |
human |
| Xiujuan Fu, Yizi He, Yongzhi Xie, Zuneng L. A conjoint analysis of bulk RNA-seq and single-nucleus RNA-seq for revealing the role of ferroptosis and iron metabolism in ALS. Frontiers in neuroscience. vol 17. 2023-03-20. PMID:36937665. |
amyotrophic lateral sclerosis (als) is a neurodegenerative disease characterized by progressive and selective degeneration of motor neurons in the motor cortex of brain and spinal cord. |
2023-03-20 |
2023-08-14 |
mouse |