| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Convit, M J de Leon, J Golomb, A E George, C Y Tarshish, M Bobinski, W Tsui, S De Santi, J Wegiel, H Wisniewsk. Hippocampal atrophy in early Alzheimer's disease: anatomic specificity and validation. The Psychiatric quarterly. vol 64. issue 4. 1993-12-08. PMID:8234547. |
hippocampal atrophy in early alzheimer's disease: anatomic specificity and validation. |
1993-12-08 |
2023-08-12 |
Not clear |
| K Ii, H Ito, E Kominami, A Hiran. Abnormal distribution of cathepsin proteinases and endogenous inhibitors (cystatins) in the hippocampus of patients with Alzheimer's disease, parkinsonism-dementia complex on Guam, and senile dementia and in the aged. Virchows Archiv. A, Pathological anatomy and histopathology. vol 423. issue 3. 1993-12-08. PMID:8236812. |
abnormal distribution of cathepsin proteinases and endogenous inhibitors (cystatins) in the hippocampus of patients with alzheimer's disease, parkinsonism-dementia complex on guam, and senile dementia and in the aged. |
1993-12-08 |
2023-08-12 |
human |
| K Ii, H Ito, E Kominami, A Hiran. Abnormal distribution of cathepsin proteinases and endogenous inhibitors (cystatins) in the hippocampus of patients with Alzheimer's disease, parkinsonism-dementia complex on Guam, and senile dementia and in the aged. Virchows Archiv. A, Pathological anatomy and histopathology. vol 423. issue 3. 1993-12-08. PMID:8236812. |
the immunolocalization of cathepsins b(cb), h and l and cystatins alpha(c alpha) and beta(c beta) were examined in the hippocampus of cases of sporadic alzheimer's disease (12 cases), parkinsonism-dementia complex on guam (eight cases), senile dementia of alzheimer type (two cases), aged subjects with marked senile change (one case) and controls (12 cases, including six normal subjects). |
1993-12-08 |
2023-08-12 |
human |
| F M Corrigan, G P Reynolds, N I War. Hippocampal tin, aluminum and zinc in Alzheimer's disease. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 6. issue 3. 1993-10-28. PMID:8400761. |
hippocampal tin, aluminum and zinc in alzheimer's disease. |
1993-10-28 |
2023-08-12 |
Not clear |
| M Ikeda, D Dewar, J McCulloc. High affinity hippocampal [3H]-glibenclamide binding sites are preserved in Alzheimer's disease. Journal of neural transmission. Parkinson's disease and dementia section. vol 5. issue 3. 1993-10-12. PMID:8369099. |
high affinity hippocampal [3h]-glibenclamide binding sites are preserved in alzheimer's disease. |
1993-10-12 |
2023-08-12 |
human |
| M Ikeda, D Dewar, J McCulloc. High affinity hippocampal [3H]-glibenclamide binding sites are preserved in Alzheimer's disease. Journal of neural transmission. Parkinson's disease and dementia section. vol 5. issue 3. 1993-10-12. PMID:8369099. |
atp-sensitive k+ channels were examined in sections of the hippocampus from patients with alzheimer's disease and age-matched control subjects by means of quantitative autoradiography. |
1993-10-12 |
2023-08-12 |
human |
| M Ikeda, D Dewar, J McCulloc. High affinity hippocampal [3H]-glibenclamide binding sites are preserved in Alzheimer's disease. Journal of neural transmission. Parkinson's disease and dementia section. vol 5. issue 3. 1993-10-12. PMID:8369099. |
there was no difference between alzheimer patients and controls in the level of high affinity [3h]-glibenclamide binding in any hippocampal region although there was a marked loss of subicular cells (reduced by 29% compared to controls) and a reduction in choline acetyltransferase activity (reduced by 60% compared to controls). |
1993-10-12 |
2023-08-12 |
human |
| M Ikeda, D Dewar, J McCulloc. High affinity hippocampal [3H]-glibenclamide binding sites are preserved in Alzheimer's disease. Journal of neural transmission. Parkinson's disease and dementia section. vol 5. issue 3. 1993-10-12. PMID:8369099. |
the results suggest that atp-sensitive k+ channels are associated with elements in the hippocampus which are preserved in alzheimer's disease. |
1993-10-12 |
2023-08-12 |
human |
| R A Armstrong, D Myers, C U Smit. The spatial patterns of beta/A4 deposit subtypes in Alzheimer's disease. Acta neuropathologica. vol 86. issue 1. 1993-10-08. PMID:8372640. |
the spatial patterns of diffuse, primitive, classic (cored) and compact (burnt-out) subtypes of beta/a4 deposits were studied in coronal sections of the frontal lobe and hippocampus, including the adjacent gyri, in nine cases of alzheimer's disease (ad). |
1993-10-08 |
2023-08-12 |
Not clear |
| Q Lu, J P Soria, J G Woo. p44mpk MAP kinase induces Alzheimer type alterations in tau function and in primary hippocampal neurons. Journal of neuroscience research. vol 35. issue 4. 1993-09-30. PMID:7689658. |
p44mpk map kinase induces alzheimer type alterations in tau function and in primary hippocampal neurons. |
1993-09-30 |
2023-08-12 |
Not clear |
| J N Joyce, C Kaeger, H Ryoo, S Goldsmit. Dopamine D2 receptors in the hippocampus and amygdala in Alzheimer's disease. Neuroscience letters. vol 154. issue 1-2. 1993-09-27. PMID:8361636. |
dopamine d2 receptors in the hippocampus and amygdala in alzheimer's disease. |
1993-09-27 |
2023-08-12 |
Not clear |
| J N Joyce, C Kaeger, H Ryoo, S Goldsmit. Dopamine D2 receptors in the hippocampus and amygdala in Alzheimer's disease. Neuroscience letters. vol 154. issue 1-2. 1993-09-27. PMID:8361636. |
the loss of d2 receptors in the hippocampus and amygdala of cases with alzheimer's disease in concert with alterations in dopaminergic innervation could contribute to the clinical symptoms of this disorder. |
1993-09-27 |
2023-08-12 |
Not clear |
| D Perani, S Bressi, S F Cappa, G Vallar, M Alberoni, F Grassi, C Caltagirone, L Cipolotti, M Franceschi, G L Lenz. Evidence of multiple memory systems in the human brain. A [18F]FDG PET metabolic study. Brain : a journal of neurology. vol 116 ( Pt 4). 1993-09-21. PMID:8353715. |
when local metabolic rates for glucose were compared with values from age- and education-matched normal controls, a common pattern of bilateral hypometabolism was present in the hippocampus, cingulate and frontal basal cortex of both global amnesia and alzheimer's disease patients. |
1993-09-21 |
2023-08-12 |
human |
| A V Vener, M V Aksenova, G Sh Burbaev. Drastic reduction of the zinc- and magnesium-stimulated protein tyrosine kinase activities in Alzheimer's disease hippocampus. FEBS letters. vol 328. issue 1-2. 1993-09-09. PMID:7688325. |
drastic reduction of the zinc- and magnesium-stimulated protein tyrosine kinase activities in alzheimer's disease hippocampus. |
1993-09-09 |
2023-08-12 |
Not clear |
| A V Vener, M V Aksenova, G Sh Burbaev. Drastic reduction of the zinc- and magnesium-stimulated protein tyrosine kinase activities in Alzheimer's disease hippocampus. FEBS letters. vol 328. issue 1-2. 1993-09-09. PMID:7688325. |
in conclusion, the zn(2+)- and mg(2+)-stimulated tyrosine kinase activities, distinct from activity of p60c-src, are decreased in alzheimer's disease hippocampus. |
1993-09-09 |
2023-08-12 |
Not clear |
| C Bouras, P R Hof, J H Morriso. Neurofibrillary tangle densities in the hippocampal formation in a non-demented population define subgroups of patients with differential early pathologic changes. Neuroscience letters. vol 153. issue 2. 1993-08-12. PMID:8327187. |
detailed analyses of the neuropathologic changes in the cerebral cortex of elderly individuals and alzheimer's disease patients have demonstrated that certain components of the neocortical and hippocampal circuits are likely to be selectively vulnerable. |
1993-08-12 |
2023-08-12 |
Not clear |
| M K Carpenter, K A Crutcher, S B Kate. An analysis of the effects of Alzheimer's plaques on living neurons. Neurobiology of aging. vol 14. issue 3. 1993-08-05. PMID:7686640. |
this was accomplished by using cryostat sections from the cerebral cortex of alzheimer's patients as a substratum for cultured rat hippocampal neurons. |
1993-08-05 |
2023-08-12 |
rat |
| J Stoll, A Balbo, B Ault, S I Rapoport, A Fin. Long-term transplants of mouse trisomy 16 hippocampal neurons, a model for Down's syndrome, do not develop Alzheimer's disease neuropathology. Brain research. vol 610. issue 2. 1993-08-03. PMID:8319091. |
long-term transplants of mouse trisomy 16 hippocampal neurons, a model for down's syndrome, do not develop alzheimer's disease neuropathology. |
1993-08-03 |
2023-08-12 |
mouse |
| G Forloni, R Chiesa, S Smiroldo, L Verga, M Salmona, F Tagliavini, N Angerett. Apoptosis mediated neurotoxicity induced by chronic application of beta amyloid fragment 25-35. Neuroreport. vol 4. issue 5. 1993-07-22. PMID:8513131. |
to investigate whether and how amyloid-beta protein (a beta) is involved in the neurodegenerative changes characteristic of alzheimer's disease (ad), primary hippocampal neurones from foetal rat brain were exposed acutely and chronically to micromolar concentrations of a synthetic peptide homologous to residues 25-35 of a beta (beta 25-35). |
1993-07-22 |
2023-08-12 |
rat |
| K Murase, T Nabeshima, Y Robitaille, R Quirion, M Ogawa, K Hayash. NGF level of is not decreased in the serum, brain-spinal fluid, hippocampus, or parietal cortex of individuals with Alzheimer's disease. Biochemical and biophysical research communications. vol 193. issue 1. 1993-07-01. PMID:8503908. |
ngf level of is not decreased in the serum, brain-spinal fluid, hippocampus, or parietal cortex of individuals with alzheimer's disease. |
1993-07-01 |
2023-08-12 |
human |