| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Giannakopoulos, P R Hof, P G Vallet, A S Giannakopoulos, Y Charnay, C Boura. Quantitative analysis of neuropathologic changes in the cerebral cortex of centenarians. Progress in neuro-psychopharmacology & biological psychiatry. vol 19. issue 4. 1996-03-22. PMID:8588057. |
the hippocampus and entorhinal cortex were often devoid of senile plaques in non-demented cases while the vast majority of alzheimer's disease cases had few sp in these regions. |
1996-03-22 |
2023-08-12 |
Not clear |
| C J Lan. Methodological problems and clinical relevance of structural neuroimaging in dementia research. Journal of neural transmission. General section. vol 99. issue 1-3. 1996-03-21. PMID:8579800. |
if based on a presumed or established etiology, however, specific neuropsychological and dementia syndromes may correspond to focal pathological changes seen in well-defined cerebral areas as recent investigations have shown with hippocampal atrophy in alzheimer's dementia. |
1996-03-21 |
2023-08-12 |
Not clear |
| B A Bah. Long-term hippocampal slices: a model system for investigating synaptic mechanisms and pathologic processes. Journal of neuroscience research. vol 42. issue 3. 1996-03-20. PMID:8583497. |
long-term slice cultures from the hippocampus, a region involved in memory encoding and one that exhibits early degeneration in alzheimer's disease and ischemia, are particularly valuable in this regard due to their expression of synaptic plasticity mechanisms (e.g., long-term potentiation) and responsiveness to pathological insults (e.g., excitotoxicity). |
1996-03-20 |
2023-08-12 |
Not clear |
| S K Maciver, C R Harringto. Two actin binding proteins, actin depolymerizing factor and cofilin, are associated with Hirano bodies. Neuroreport. vol 6. issue 15. 1996-03-19. PMID:8580423. |
however, we could detect no difference in the levels of expression of either adf or cofilin in the hippocampal tissue from normal individuals and alzheimer's disease patients. |
1996-03-19 |
2023-08-12 |
Not clear |
| Y Fukutani, K Kobayashi, I Nakamura, K Watanabe, K Isaki, N J Cairn. Neurons, intracellular and extracellular neurofibrillary tangles in subdivisions of the hippocampal cortex in normal ageing and Alzheimer's disease. Neuroscience letters. vol 200. issue 1. 1996-03-19. PMID:8584267. |
neurons, intracellular and extracellular neurofibrillary tangles in subdivisions of the hippocampal cortex in normal ageing and alzheimer's disease. |
1996-03-19 |
2023-08-12 |
human |
| Y Fukutani, K Kobayashi, I Nakamura, K Watanabe, K Isaki, N J Cairn. Neurons, intracellular and extracellular neurofibrillary tangles in subdivisions of the hippocampal cortex in normal ageing and Alzheimer's disease. Neuroscience letters. vol 200. issue 1. 1996-03-19. PMID:8584267. |
unaffected neurons, intracellular neurofibrillary tangles (i-nfts) and extracellular nfts (e-nfts) in six normal subjects and six patients with alzheimer's disease (ad) were morphometrically evaluated in eight subdivisions of the hippocampal cortex, using the gallyas silver impregnation technique modified by the application of hematoxylin and eosin. |
1996-03-19 |
2023-08-12 |
human |
| L Parnetti, D T Lowenthal, O Presciutti, G P Pelliccioli, R Palumbo, G Gobbi, P Chiarini, B Palumbo, R Tarducci, U Seni. 1H-MRS, MRI-based hippocampal volumetry, and 99mTc-HMPAO-SPECT in normal aging, age-associated memory impairment, and probable Alzheimer's disease. Journal of the American Geriatrics Society. vol 44. issue 2. 1996-03-14. PMID:8576501. |
1h-mrs, mri-based hippocampal volumetry, and 99mtc-hmpao-spect in normal aging, age-associated memory impairment, and probable alzheimer's disease. |
1996-03-14 |
2023-08-12 |
Not clear |
| S Yamaguchi, T Nakagawa, H Arai, H Sasaki, S Higuchi, J Q Trojanowsk. Temporal progression of hippocampal atrophy and apolipoprotein E gene in Alzheimer's disease. Journal of the American Geriatrics Society. vol 44. issue 2. 1996-03-14. PMID:8576522. |
temporal progression of hippocampal atrophy and apolipoprotein e gene in alzheimer's disease. |
1996-03-14 |
2023-08-12 |
Not clear |
| M Simons, B de Strooper, G Multhaup, P J Tienari, C G Dotti, K Beyreuthe. Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 16. issue 3. 1996-02-28. PMID:8558258. |
based on the observation that mature hippocampal neurons produce two potentially amyloidogenic fragments and secrete substantial amounts of beta a4 when expressing human app, our results strengthen the hypothesis that neurons play a central role in the process of beta a4 deposition in cases of alzheimer's disease and in aged primates. |
1996-02-28 |
2023-08-12 |
human |
| P Kasa, P Szerdahelyi, H M Wisniewsk. Lack of topographical relationship between sites of aluminum deposition and senile plaques in the Alzheimer's disease brain. Acta neuropathologica. vol 90. issue 5. 1996-02-28. PMID:8560987. |
histochemical demonstration of aluminum in autopsy brains from alzheimer's disease victims by means of the solochrome azurine method in combination with the methenamine silver technique revealed aluminum-related staining in some neocortical and hippocampal senile plaques and tangles, as well as in the cytoplasm and/or the nuclei of some neurons, and in the cytoplasm of endothelial cells of blood capillaries and pericytes around larger blood vessels. |
1996-02-28 |
2023-08-12 |
Not clear |
| J G Sheng, R E Mrak, W S Griffi. Microglial interleukin-1 alpha expression in brain regions in Alzheimer's disease: correlation with neuritic plaque distribution. Neuropathology and applied neurobiology. vol 21. issue 4. 1996-01-11. PMID:7494597. |
in alzheimer's disease, tau 2+ neuritic plaques occurred with increasing frequency in grey matter of frontal and occipital lobes, temporal lobe, and hippocampus. |
1996-01-11 |
2023-08-12 |
Not clear |
| J P Brion, J Flament-Duran. Distribution and expression of the alpha-tubulin mRNA in the hippocampus and the temporal cortex in Alzheimer's disease. Pathology, research and practice. vol 191. issue 6. 1995-12-15. PMID:7479369. |
distribution and expression of the alpha-tubulin mrna in the hippocampus and the temporal cortex in alzheimer's disease. |
1995-12-15 |
2023-08-12 |
human |
| J P Brion, J Flament-Duran. Distribution and expression of the alpha-tubulin mRNA in the hippocampus and the temporal cortex in Alzheimer's disease. Pathology, research and practice. vol 191. issue 6. 1995-12-15. PMID:7479369. |
the distribution of the messenger rna for alpha-tubulin has been investigated by in situ hybridization in the human hippocampus and temporal cortex in normal subjects and in alzheimer's disease. |
1995-12-15 |
2023-08-12 |
human |
| D L Price, S S Sisodia, S E Gand. Amyloid beta amyloidosis in Alzheimer's disease. Current opinion in neurology. vol 8. issue 4. 1995-12-12. PMID:7582041. |
the presence of amyloid deposits in the parenchyma of the amygdala, hippocampus, and neocortex is a major histopathological hallmark of alzheimer's disease. |
1995-12-12 |
2023-08-12 |
Not clear |
| M Lehtovirta, M P Laakso, H Soininen, S Helisalmi, A Mannermaa, E L Helkala, K Partanen, M Ryynänen, P Vainio, P Hartikaine. Volumes of hippocampus, amygdala and frontal lobe in Alzheimer patients with different apolipoprotein E genotypes. Neuroscience. vol 67. issue 1. 1995-12-04. PMID:7477910. |
volumes of hippocampus, amygdala and frontal lobe in alzheimer patients with different apolipoprotein e genotypes. |
1995-12-04 |
2023-08-12 |
Not clear |
| M Lehtovirta, M P Laakso, H Soininen, S Helisalmi, A Mannermaa, E L Helkala, K Partanen, M Ryynänen, P Vainio, P Hartikaine. Volumes of hippocampus, amygdala and frontal lobe in Alzheimer patients with different apolipoprotein E genotypes. Neuroscience. vol 67. issue 1. 1995-12-04. PMID:7477910. |
here, we wanted to study the effect of apolipoprotein e genotype on the magnitude of damage in the hippocampus, where a marked synapse loss exists in alzheimer's disease. |
1995-12-04 |
2023-08-12 |
Not clear |
| M Lehtovirta, M P Laakso, H Soininen, S Helisalmi, A Mannermaa, E L Helkala, K Partanen, M Ryynänen, P Vainio, P Hartikaine. Volumes of hippocampus, amygdala and frontal lobe in Alzheimer patients with different apolipoprotein E genotypes. Neuroscience. vol 67. issue 1. 1995-12-04. PMID:7477910. |
we measured by magnetic resonance imaging the volumes of the hippocampus, amygdala, and frontal lobes in the three alzheimer subgroups: patients with 2, 1 or 0 e4 alleles. |
1995-12-04 |
2023-08-12 |
Not clear |
| M Lehtovirta, M P Laakso, H Soininen, S Helisalmi, A Mannermaa, E L Helkala, K Partanen, M Ryynänen, P Vainio, P Hartikaine. Volumes of hippocampus, amygdala and frontal lobe in Alzheimer patients with different apolipoprotein E genotypes. Neuroscience. vol 67. issue 1. 1995-12-04. PMID:7477910. |
we found that alzheimer patients with e4/4 genotype (n = 5) had smaller volumes of the hippocampus and the amygdala than those with e3/4 (n = 9) and those with e3/3 or e2/3 (n = 12). |
1995-12-04 |
2023-08-12 |
Not clear |
| K Hensley, N Hall, R Subramaniam, P Cole, M Harris, M Aksenov, M Aksenova, S P Gabbita, J F Wu, J M Carne. Brain regional correspondence between Alzheimer's disease histopathology and biomarkers of protein oxidation. Journal of neurochemistry. vol 65. issue 5. 1995-12-04. PMID:7595501. |
four biomarkers of neuronal protein oxidation [w/s ratio of mal-6 spin-labeled synaptosomes, phenylhydrazine-reactive protein carbonyl content, glutamine synthetase (gs) activity, creatine kinase (ck) activity] in three brain regions [cerebellum, inferior parietal lobule (ipl), and hippocampus (hip)] of alzheimer's disease (ad)-demented and age-matched control subjects were assessed. |
1995-12-04 |
2023-08-12 |
human |
| I Blümcke, H K Wolf, P R Hof, J H Morrison, O D Wiestle. Regional distribution of the AMPA glutamate receptor subunits GluR2(4) in human hippocampus. Brain research. vol 682. issue 1-2. 1995-11-09. PMID:7552321. |
these findings may provide basic information for studies of the glur2(4) subunit in human hippocampus during various neuropathological conditions, such as temporal lobe epilepsy, ischemia and alzheimer's disease. |
1995-11-09 |
2023-08-12 |
human |