| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N J Lane, A Balbo, S I Rapopor. A fine structural study of the hippocampus and dorsal root ganglion in mouse trisomy 16, a model of Down's syndrome. Cell biology international. vol 20. issue 10. 1997-04-03. PMID:8969460. |
when related to fine structural studies of transplanted embryonic ts16 hippocampus which have been maintained for long periods of time, these results indicate that the trisomic mouse brain would not be useful as a structural model for down's syndrome and hence presenile alzheimer's disease, as it is not associated with any detectable morphological abnormality. |
1997-04-03 |
2023-08-12 |
mouse |
| K Wakabayashi, L A Hansen, I Vincent, M Mallory, E Maslia. Neurofibrillary tangles in the dentate granule cells of patients with Alzheimer's disease, Lewy body disease and progressive supranuclear palsy. Acta neuropathologica. vol 93. issue 1. 1997-04-01. PMID:9006651. |
recent studies have shown that the dentate granular cells of the hippocampus are affected in patients with alzheimer's disease (ad). |
1997-04-01 |
2023-08-12 |
Not clear |
| B Connor, D Young, P Lawlor, W Gai, H Waldvogel, R L Faull, M Draguno. Trk receptor alterations in Alzheimer's disease. Brain research. Molecular brain research. vol 42. issue 1. 1997-03-25. PMID:8915574. |
truncated trkb receptors were found in high levels in senile plaques, while the full-length receptor was expressed in glial-like cells in the hippocampus of alzheimer's disease brains. |
1997-03-25 |
2023-08-12 |
human |
| J Fergusson, M Landon, J Lowe, S P Dawson, R Layfield, D P Hanger, R J Maye. Pathological lesions of Alzheimer's disease and dementia with Lewy bodies brains exhibit immunoreactivity to an ATPase that is a regulatory subunit of the 26S proteasome. Neuroscience letters. vol 219. issue 3. 1997-03-20. PMID:8971806. |
localisation of this atpase in histological sections of hippocampus from alzheimer's disease (ad) and in cingulate gyrus sections of dementia with lewy bodies (dlb) brains was examined immunohistochemically. |
1997-03-20 |
2023-08-12 |
Not clear |
| M A Deibel, W D Ehmann, W R Markesber. Copper, iron, and zinc imbalances in severely degenerated brain regions in Alzheimer's disease: possible relation to oxidative stress. Journal of the neurological sciences. vol 143. issue 1-2. 1997-03-20. PMID:8981312. |
copper (cu), iron (fe), and zinc (zn) levels in five different brain regions (amygdala, hippocampus, inferior parietal lobule, superior and middle temporal gyri, and cerebellum) were determined by instrumental neutron activation analysis (inaa) in samples from alzheimer's disease (ad) patients and age-matched control subjects. |
1997-03-20 |
2023-08-12 |
human |
| P L DiPatre, B B Gelma. Microglial cell activation in aging and Alzheimer disease: partial linkage with neurofibrillary tangle burden in the hippocampus. Journal of neuropathology and experimental neurology. vol 56. issue 2. 1997-03-18. PMID:9034367. |
microglial cell activation in aging and alzheimer disease: partial linkage with neurofibrillary tangle burden in the hippocampus. |
1997-03-18 |
2023-08-12 |
human |
| J A Harder, C J Maclean, J T Alder, P T Francis, R M Ridle. The 5-HT1A antagonist, WAY 100635, ameliorates the cognitive impairment induced by fornix transection in the marmoset. Psychopharmacology. vol 127. issue 3. 1997-03-11. PMID:8912403. |
since cholinergic loss in the hippocampus (and neocortex) occurs in association with cognitive decline in alzheimer's disease, these results suggest that 5-ht1a antagonists may have a role in the treatment of some of the cognitive symptoms of dementia. |
1997-03-11 |
2023-08-12 |
marmoset |
| S Mitake, E Katada, Y Otsuka, N Matsukawa, T Iwase, T Tsugu, O Fujimori, K Ojik. Possible implication of hippocampal cholinergic neurostimulating peptide (HCNP)-related components in Hirano body formation. Neuropathology and applied neurobiology. vol 22. issue 5. 1997-03-11. PMID:8930956. |
we have previously demonstrated that hippocampal cholinergic neurostimulating peptide (hcnp)-related components accumulate in almost all hirano bodies in sommer's sector of the hippocampus of elderly individuals, and that the number of hcnp-positive hirano bodies is greater in patients with alzheimer's disease. |
1997-03-11 |
2023-08-12 |
Not clear |
| P J Norris, R L Faull, P C Emso. Neuronal nitric oxide synthase (nNOS) mRNA expression and NADPH-diaphorase staining in the frontal cortex, visual cortex and hippocampus of control and Alzheimer's disease brains. Brain research. Molecular brain research. vol 41. issue 1-2. 1997-02-20. PMID:8883932. |
neuronal nitric oxide synthase (nnos) mrna expression and nadph-diaphorase staining in the frontal cortex, visual cortex and hippocampus of control and alzheimer's disease brains. |
1997-02-20 |
2023-08-12 |
human |
| P J Norris, R L Faull, P C Emso. Neuronal nitric oxide synthase (nNOS) mRNA expression and NADPH-diaphorase staining in the frontal cortex, visual cortex and hippocampus of control and Alzheimer's disease brains. Brain research. Molecular brain research. vol 41. issue 1-2. 1997-02-20. PMID:8883932. |
neuronal nitric oxide synthase (nnos) mrna levels and nadph diaphorase (nadph-d) staining were compared in the frontal cortex, visual cortex and hippocampus (dentate gyrus and ca subfields of ammon's horn) of five alzheimer's disease (ad) and six control brains. |
1997-02-20 |
2023-08-12 |
human |
| N C Fox, E K Warrington, P A Freeborough, P Hartikainen, A M Kennedy, J M Stevens, M N Rosso. Presymptomatic hippocampal atrophy in Alzheimer's disease. A longitudinal MRI study. Brain : a journal of neurology. vol 119 ( Pt 6). 1997-02-18. PMID:9010004. |
presymptomatic hippocampal atrophy in alzheimer's disease. |
1997-02-18 |
2023-08-12 |
human |
| A Ueki, C Miwa, K Oohara, K Miyosh. Histological evidence for cholinergic alteration in the hippocampus following entorhinal cortex lesion. Journal of the neurological sciences. vol 142. issue 1-2. 1997-02-07. PMID:8902712. |
this study demonstrates the importance of the entorhinal cortex in the hippocampal cholinergic function which appears to be important to memory and learning, and raises the possibility that memory deficit in alzheimer's disease may be associated with partial neuronal loss in the entorhinal cortex. |
1997-02-07 |
2023-08-12 |
rat |
| A I Kiktenko, N A Uranova, D V Deniso. [The quantitative characteristics of the changes in the synaptic contacts in the hippocampus in Alzheimer's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 96. issue 5. 1997-02-06. PMID:9012266. |
[the quantitative characteristics of the changes in the synaptic contacts in the hippocampus in alzheimer's disease]. |
1997-02-06 |
2023-08-12 |
Not clear |
| T Kimura, T Ono, J Takamatsu, H Yamamoto, K Ikegami, A Kondo, M Hasegawa, Y Ihara, E Miyamoto, T Miyakaw. Sequential changes of tau-site-specific phosphorylation during development of paired helical filaments. Dementia (Basel, Switzerland). vol 7. issue 4. 1997-01-30. PMID:8835879. |
we investigated the phosphorylation of tau in the hippocampus of nondemented patients and alzheimer's disease patients by immunostaining with five site-specific antibodies against phosphorylated tau. |
1997-01-30 |
2023-08-12 |
human |
| R Horn, B Ostertun, M Fric, L Solymosi, A Steudel, H J Mölle. Atrophy of hippocampus in patients with Alzheimer's disease and other diseases with memory impairment. Dementia (Basel, Switzerland). vol 7. issue 4. 1997-01-30. PMID:8835880. |
atrophy of hippocampus in patients with alzheimer's disease and other diseases with memory impairment. |
1997-01-30 |
2023-08-12 |
Not clear |
| S W Scheff, D L Sparks, D A Pric. Quantitative assessment of synaptic density in the outer molecular layer of the hippocampal dentate gyrus in Alzheimer's disease. Dementia (Basel, Switzerland). vol 7. issue 4. 1997-01-30. PMID:8835888. |
quantitative assessment of synaptic density in the outer molecular layer of the hippocampal dentate gyrus in alzheimer's disease. |
1997-01-30 |
2023-08-12 |
human |
| D M Appelt, G C Kopen, L J Boyne, B J Bali. Localization of transglutaminase in hippocampal neurons: implications for Alzheimer's disease. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 44. issue 12. 1997-01-28. PMID:8985134. |
localization of transglutaminase in hippocampal neurons: implications for alzheimer's disease. |
1997-01-28 |
2023-08-12 |
rat |
| D M Armstrong, M D Ikonomovi. AMPA-selective glutamate receptor subtype immunoreactivity in the hippocampal dentate gyrus of patients with Alzheimer disease. Evidence for hippocampal plasticity. Molecular and chemical neuropathology. vol 28. issue 1-3. 1997-01-23. PMID:8871942. |
ampa-selective glutamate receptor subtype immunoreactivity in the hippocampal dentate gyrus of patients with alzheimer disease. |
1997-01-23 |
2023-08-12 |
Not clear |
| C Behl, F Lezoualc'h, T Trapp, M Widmann, T Skutella, F Holsboe. Glucocorticoids enhance oxidative stress-induced cell death in hippocampal neurons in vitro. Endocrinology. vol 138. issue 1. 1997-01-23. PMID:8977391. |
in patients with alzheimer's disease, hippocampal cells are among the first neuronal cells of the brain to degenerate. |
1997-01-23 |
2023-08-12 |
mouse |
| C Behl, F Lezoualc'h, T Trapp, M Widmann, T Skutella, F Holsboe. Glucocorticoids enhance oxidative stress-induced cell death in hippocampal neurons in vitro. Endocrinology. vol 138. issue 1. 1997-01-23. PMID:8977391. |
two oxidative stressors were investigated, the free radical-inducing alzheimer's disease-associated amyloid beta-protein, which is toxic to hippocampal neurons, and the excitatory amino acid glutamate, which induces oxidative cell death in ht22 cells via an increase in intracellular peroxides. |
1997-01-23 |
2023-08-12 |
mouse |