| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P A Freeborough, N C Fox, R I Kitne. Interactive algorithms for the segmentation and quantitation of 3-D MRI brain scans. Computer methods and programs in biomedicine. vol 53. issue 1. 1997-07-22. PMID:9113464. |
the efficacy of one method in measuring volume loss (atrophy) of the hippocampus in alzheimer's disease is shown and is compared to conventional methods. |
1997-07-22 |
2023-08-12 |
Not clear |
| E A Lukyanet. Evidence for colocalization of calcineurin and calcium channels in dorsal root ganglion neurons. Neuroscience. vol 78. issue 3. 1997-07-21. PMID:9153645. |
obviously, calcineurin can also be involved in numerous brain diseases, such as ischaemic hippocampal damage when the protein dephosphorylation system is markedly altered and hyperphosphorylation of the microtubule system in alzheimer's disease. |
1997-07-21 |
2023-08-12 |
rat |
| Y Nakamura, R Hasimoto, Y Kashiwagi, Y Miyamae, K Shinosaki, T Nishikawa, H Hattori, T Kudo, M Taked. Abnormal distribution of neurofilament L in neurons with Alzheimer's disease. Neuroscience letters. vol 225. issue 3. 1997-07-18. PMID:9147405. |
free-floating sections of the hippocampus with alzheimer's disease were studied immunohistochemically, using a polyclonal antibody specifically bound to the tail region of neurofilament l (nf-l). |
1997-07-18 |
2023-08-12 |
Not clear |
| M J Connor, N Sidel. Retinoic acid synthesis in normal and Alzheimer diseased brain and human neural cells. Molecular and chemical neuropathology. vol 30. issue 3. 1997-07-18. PMID:9165489. |
the rldh activity of hippocampus and parietal cortex from alzheimer diseased brains was 1.5- to 2-fold higher (p < 0.05) compared to the controls. |
1997-07-18 |
2023-08-12 |
human |
| M J Connor, N Sidel. Retinoic acid synthesis in normal and Alzheimer diseased brain and human neural cells. Molecular and chemical neuropathology. vol 30. issue 3. 1997-07-18. PMID:9165489. |
however, this feedback mechanism does not appear to explain the higher rldh activity of alzheimer diseased hippocampus and parietal cortex, because the overall vitamin a status as indicated by serum retinol and carotenoid levels and by hippocampal retinoid content was similar for the alzheimer diseased and control groups. |
1997-07-18 |
2023-08-12 |
human |
| H S Ved, M L Koenig, J R Dave, B P Docto. Huperzine A, a potential therapeutic agent for dementia, reduces neuronal cell death caused by glutamate. Neuroreport. vol 8. issue 4. 1997-07-14. PMID:9141073. |
huperzine a, a potential therapeutic agent for alzheimer's disease, inhibits acetylcholinesterase in primary cultures derived from forebrain, hippocampus, cortex and cerebellum of embryonic rat brain. |
1997-07-14 |
2023-08-12 |
rat |
| C M Shaw, E C Alvor. Neuropathology of the limbic system. Neuroimaging clinics of North America. vol 7. issue 1. 1997-07-10. PMID:9100234. |
the diseases involving the limbic system are divided into three groups; (1) diseases in which the limbic system is more or less selectively involved, such as limbic encephalitis, herpes simplex encephalitis, cerebral confusions by the falx and tentorium, and internal herniations through the falx and tentorium; (2) diseases in which the limbic system is predominantly involved, such as arhinencephalia, holoprosencephaly, cyst of cavum septi pellucidi, pick's disease, alzheimer's disease, hippocampal sclerosis, and vascular diseases of the hippocampal formation; and (3) diseases in which the limbic system is randomly involved, such as various types of neoplasms and vascular and inflammatory lesions. |
1997-07-10 |
2023-08-12 |
Not clear |
| R Fama, E V Sullivan, P K Shear, L Marsh, J A Yesavage, J R Tinklenberg, K O Lim, A Pfefferbau. Selective cortical and hippocampal volume correlates of Mattis Dementia Rating Scale in Alzheimer disease. Archives of neurology. vol 54. issue 6. 1997-07-10. PMID:9193207. |
selective cortical and hippocampal volume correlates of mattis dementia rating scale in alzheimer disease. |
1997-07-10 |
2023-08-12 |
Not clear |
| Z Nagy, M M Esiri, A D Smit. Expression of cell division markers in the hippocampus in Alzheimer's disease and other neurodegenerative conditions. Acta neuropathologica. vol 93. issue 3. 1997-06-19. PMID:9083562. |
expression of cell division markers in the hippocampus in alzheimer's disease and other neurodegenerative conditions. |
1997-06-19 |
2023-08-12 |
human |
| G A MacGibbon, P A Lawlor, E S Sirimanne, M R Walton, B Connor, D Young, C Williams, P Gluckman, R L Faull, P Hughes, M Draguno. Bax expression in mammalian neurons undergoing apoptosis, and in Alzheimer's disease hippocampus. Brain research. vol 750. issue 1-2. 1997-06-17. PMID:9098548. |
bax expression in mammalian neurons undergoing apoptosis, and in alzheimer's disease hippocampus. |
1997-06-17 |
2023-08-12 |
rat |
| M M Nicolle, A Shivers, T M Gill, M Gallaghe. Hippocampal N-methyl-D-aspartate and kainate binding in response to entorhinal cortex aspiration or 192 IgG-saporin lesions of the basal forebrain. Neuroscience. vol 77. issue 3. 1997-06-10. PMID:9070742. |
the entorhinal and cholinergic lesions were used as in vivo models of the degeneration of hippocampal input that occurs in normal aging and alzheimer's disease. |
1997-06-10 |
2023-08-12 |
rat |
| M M Nicolle, A Shivers, T M Gill, M Gallaghe. Hippocampal N-methyl-D-aspartate and kainate binding in response to entorhinal cortex aspiration or 192 IgG-saporin lesions of the basal forebrain. Neuroscience. vol 77. issue 3. 1997-06-10. PMID:9070742. |
the results from the present lesion study suggest that some, but not all, of the effects on hippocampal [3h]kainate and n-methyl-d-aspartate binding induced by the lesions are consistent with the status of binding to these receptors in aging and alzheimer's disease. |
1997-06-10 |
2023-08-12 |
rat |
| M M Nicolle, A Shivers, T M Gill, M Gallaghe. Hippocampal N-methyl-D-aspartate and kainate binding in response to entorhinal cortex aspiration or 192 IgG-saporin lesions of the basal forebrain. Neuroscience. vol 77. issue 3. 1997-06-10. PMID:9070742. |
consistent with the effects of aging and alzheimer's disease is an altered topography of [3h]kainate binding after entorhinal cortex lesion and a modest decline in n-methyl-d-aspartate binding after lesions of the cholinergic septal input to the hippocampus. |
1997-06-10 |
2023-08-12 |
rat |
| M T Rajan, K S Jagannatha Rao, B M Mamatha, R V Rao, P Shanmugavelu, R B Menon, M V Pavithra. Quantification of trace elements in normal human brain by inductively coupled plasma atomic emission spectrometry. Journal of the neurological sciences. vol 146. issue 2. 1997-06-09. PMID:9077512. |
ratios of al to fe were found to be high in temporal cerebrum (8.07) and hippocampus (9.05) and these two regions are significantly involved in alzheimer's disease. |
1997-06-09 |
2023-08-12 |
human |
| b' G Simi\\xc4\\x87, I Kostovi\\xc4\\x87, B Winblad, N Bogdanovi\\xc4\\x8. Volume and number of neurons of the human hippocampal formation in normal aging and Alzheimer\'s disease. The Journal of comparative neurology. vol 379. issue 4. 1997-06-06. PMID:9067838.' |
in order to observe changes owing to aging and alzheimer's disease (ad) in the volumes of subdivisions of the hippocampus and the number of neurons of the hippocampal formation, 18 normal brains from subjects who died of nonneurological causes and had no history of long-term illness or dementia (ten of these brains comprised the aged control group) and 13 ad brains were analyzed. |
1997-06-06 |
2023-08-12 |
human |
| G T Bartoo, D Nochlin, D Chang, Y Kim, S M Sum. The mean A beta load in the hippocampus correlates with duration and severity of dementia in subgroups of Alzheimer disease. Journal of neuropathology and experimental neurology. vol 56. issue 5. 1997-06-03. PMID:9143266. |
the mean a beta load in the hippocampus correlates with duration and severity of dementia in subgroups of alzheimer disease. |
1997-06-03 |
2023-08-12 |
human |
| D S Woodruff-Pak, Y T Li, R M Hinchliffe, R L Por. Hippocampus in delay eyeblink classical conditioning: essential for nefiracetam amelioration of learning in older rabbits. Brain research. vol 747. issue 2. 1997-05-27. PMID:9045995. |
because of the parallels between conditioning in rabbits with disrupted hippocampal cholinergic systems and conditioning in alzheimer's disease (ad), these results suggest that nefiracetam may ameliorate conditioning in ad as it ameliorates conditioning in older rabbits. |
1997-05-27 |
2023-08-12 |
Not clear |
| S Doré, S Kar, R Quirio. Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- and human amylin-induced toxicity. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 9. 1997-05-27. PMID:9114067. |
igfs possess neurotrophic activities in the hippocampus, an area severely affected in alzheimer disease. |
1997-05-27 |
2023-08-12 |
human |
| S Doré, S Kar, R Quirio. Insulin-like growth factor I protects and rescues hippocampal neurons against beta-amyloid- and human amylin-induced toxicity. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 9. 1997-05-27. PMID:9114067. |
these data, together with the evidence that beta-amyloid (abeta)-derived peptides likely play an important role in the neurodegenerative process observed in alzheimer disease, led us to investigate if igfs could be neuroprotective to hippocampal neurons against toxicity induced by amyloidogenic derivatives. |
1997-05-27 |
2023-08-12 |
human |
| P J Tienari, N Ida, E Ikonen, M Simons, A Weidemann, G Multhaup, C L Masters, C G Dotti, K Beyreuthe. Intracellular and secreted Alzheimer beta-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 8. 1997-05-22. PMID:9108116. |
intracellular and secreted alzheimer beta-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons. |
1997-05-22 |
2023-08-12 |
human |