| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R C McRee, S F Boulay, V K Sood, E I Cohen, V I Cohen, M S Gitler, B R Zeeberg, R E Gibson, R C Reb. Autoradiographic evidence that QNB displays in vivo selectivity for the m2 subtype. NeuroImage. vol 2. issue 1. 1997-12-02. PMID:9343590. |
alzheimer's disease (ad) involves selective loss of muscarinic m2, but not m1, subtype neuroreceptors in cortical and hippocampal regions of the human brain. |
1997-12-02 |
2023-08-12 |
human |
| S F Boulay, V K Sood, M R Rayeq, R C McRee, E I Cohen, V I Cohen, B R Zeeberg, R C Reb. Autoradiographic evidence that quinuclidinyl 4-(bromophenyl)-2-thienylglycolate (QBPTG) displays in vivo selectivity for the muscarinic m2 subtype. NeuroImage. vol 2. issue 3. 1997-12-02. PMID:9343604. |
alzheimer's disease (ad) involves selective loss of muscarinic m2, but not m1, subtype neuroreceptors in cortical and hippocampal regions of the human brain. |
1997-12-02 |
2023-08-12 |
human |
| S F Boulay, V K Sood, M R Rayeq, V I Cohen, B R Zeeberg, R C Reb. Autoradiographic evidence that 3-quinuclidinyl-4-fluorobenzilate (FQNB) displays in vivo selectivity for the m2 subtype. NeuroImage. vol 3. issue 1. 1997-12-02. PMID:9345473. |
alzheimer's disease (ad) involves selective loss of muscarinic m2, but not m1, subtype neuroreceptors in cortical and hippocampal regions of the human brain. |
1997-12-02 |
2023-08-12 |
human |
| G Danscher, K B Jensen, C J Frederickson, K Kemp, A Andreasen, S Juhl, M Stoltenberg, R Ravi. Increased amount of zinc in the hippocampus and amygdala of Alzheimer's diseased brains: a proton-induced X-ray emission spectroscopic analysis of cryostat sections from autopsy material. Journal of neuroscience methods. vol 76. issue 1. 1997-11-26. PMID:9334939. |
increased amount of zinc in the hippocampus and amygdala of alzheimer's diseased brains: a proton-induced x-ray emission spectroscopic analysis of cryostat sections from autopsy material. |
1997-11-26 |
2023-08-12 |
human |
| Y Fukutani, K Sasaki, M Mukai, R Matsubara, K Isaki, N J Cairn. Neurons and extracellular neurofibrillary tangles in the hippocampal subdivisions in early-onset familial Alzheimer's disease: a case study. Psychiatry and clinical neurosciences. vol 51. issue 4. 1997-11-21. PMID:9316169. |
neurons and extracellular neurofibrillary tangles in the hippocampal subdivisions in early-onset familial alzheimer's disease: a case study. |
1997-11-21 |
2023-08-12 |
Not clear |
| Y Fukutani, K Sasaki, M Mukai, R Matsubara, K Isaki, N J Cairn. Neurons and extracellular neurofibrillary tangles in the hippocampal subdivisions in early-onset familial Alzheimer's disease: a case study. Psychiatry and clinical neurosciences. vol 51. issue 4. 1997-11-21. PMID:9316169. |
we have investigated morphometrically unaffected neurons, intracellular neurofibrillary tangles (i-nft) and extracellular neurofibrillary tangles (e-nft) in eight subdivisions of the hippocampal cortex in two cases of early-onset familial alzheimer's disease (fad) and six cases of early-onset sporadic alzheimer's disease (sad). |
1997-11-21 |
2023-08-12 |
Not clear |
| A Ueki, C Miwa, H Shinjo, M Kokai, Y Morit. Synapse alteration in hippocampal CA3 field following entorhinal cortex lesion. Journal of the neurological sciences. vol 151. issue 1. 1997-11-20. PMID:9335002. |
to model one aspect of the neurodegeneration observed in alzheimer's disease and to investigate the synaptic alteration of the hippocampus associated with entorhinal cortex lesion, ibotenic acid was used to produce selective unilateral neuronal loss in rat entorhinal cortex. |
1997-11-20 |
2023-08-12 |
rat |
| M J de Leon, T McRae, H Rusinek, A Convit, S De Santi, C Tarshish, J Golomb, N Volkow, K Daisley, N Orentreich, B McEwe. Cortisol reduces hippocampal glucose metabolism in normal elderly, but not in Alzheimer's disease. The Journal of clinical endocrinology and metabolism. vol 82. issue 10. 1997-11-17. PMID:9329348. |
cortisol reduces hippocampal glucose metabolism in normal elderly, but not in alzheimer's disease. |
1997-11-17 |
2023-08-12 |
human |
| J H Morrison, P R Ho. Life and death of neurons in the aging brain. Science (New York, N.Y.). vol 278. issue 5337. 1997-11-05. PMID:9334292. |
in this article, the qualitative and quantitative differences between aging and alzheimer's disease with respect to neuron loss are discussed, and age-related changes in functional and biochemical attributes of hippocampal circuits that might mediate functional decline in the absence of neuron death are explored. |
1997-11-05 |
2023-08-12 |
Not clear |
| W R Markesber. Neuropathological criteria for the diagnosis of Alzheimer's disease. Neurobiology of aging. vol 18. issue 4 Suppl. 1997-10-31. PMID:9330980. |
the definitive diagnosis of alzheimer's disease (ad) is made at autopsy by the presence of abundant neuritic plaques (np) and neurofibrillary tangles (nft) in the neocortex, entorhinal cortex, and hippocampus. |
1997-10-31 |
2023-08-12 |
Not clear |
| J Ulas, C W Cotma. Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain. Neuroscience. vol 79. issue 4. 1997-10-23. PMID:9219960. |
an antisense oligonucleotide probe was used to examine the expression of gene encoding the obligatory nmdar1 subunit of the n-methyl-d-aspartate receptor in the hippocampus and adjacent cortical areas (entorhinal and perirhinal cortices) of seven alzheimer patients and in the same brain regions of seven control individuals. |
1997-10-23 |
2023-08-12 |
human |
| J Ulas, C W Cotma. Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain. Neuroscience. vol 79. issue 4. 1997-10-23. PMID:9219960. |
these data suggest that reduction in expression of the nmdar1 gene observed in certain regions of alzheimer hippocampus and adjacent cortical regions is specific for the disease itself. |
1997-10-23 |
2023-08-12 |
human |
| J Ulas, C W Cotma. Decreased expression of N-methyl-D-aspartate receptor 1 messenger RNA in select regions of Alzheimer brain. Neuroscience. vol 79. issue 4. 1997-10-23. PMID:9219960. |
we postulate that reduced transcript levels may reflect either regional cell loss or anomalies in glutamatergic input to the hippocampus and entorhinal cortex in alzheimer's disease. |
1997-10-23 |
2023-08-12 |
human |
| E Master, S L Chan, Z Ali-Kha. Ubiquitin (Ub) interacts non-covalently with Alzheimer amyloid precursor protein (betaPP): isolation of Ub-betaPP conjugates from brain extracts. Neuroreport. vol 8. issue 12. 1997-10-23. PMID:9295117. |
ubiquitin (ub)-immunocytochemistry on alzheimer's disease (ad) brain sections shows diverse ub-associated deposits in the neuropil and senile plaques, elevated levels of ub reactivity in hippocampal neurons and glia, and co-localization of ub and beta-amyloid precursor protein (betapp) epitope reactivity in dystrophic axons. |
1997-10-23 |
2023-08-12 |
Not clear |
| N G Campeau, R C Petersen, J P Felmlee, P C O'Brien, C R Jac. Hippocampal transverse relaxation times in patients with Alzheimer disease. Radiology. vol 205. issue 1. 1997-10-23. PMID:9314985. |
hippocampal transverse relaxation times in patients with alzheimer disease. |
1997-10-23 |
2023-08-12 |
human |
| N G Campeau, R C Petersen, J P Felmlee, P C O'Brien, C R Jac. Hippocampal transverse relaxation times in patients with Alzheimer disease. Radiology. vol 205. issue 1. 1997-10-23. PMID:9314985. |
to determine whether hippocampal relaxation times in magnetic resonance (mr) imaging differ between patients with probable alzheimer disease and elderly control subjects with normal cognition. |
1997-10-23 |
2023-08-12 |
human |
| M R Roberson, K Kolasa, D S Parsons, L E Harrel. Cholinergic denervation and sympathetic ingrowth result in persistent changes in hippocampal muscarinic receptors. Neuroscience. vol 80. issue 2. 1997-10-17. PMID:9284344. |
our laboratory has been utilizing the model of hippocampal sympathetic ingrowth, which has been suggested to occur in alzheimer's disease, to investigate the effects of cholinergic denervation and hippocampal rearrangements. |
1997-10-17 |
2023-08-12 |
rat |
| C Bouras, P Giannakopoulos, P F Good, A Hsu, P R Hof, D P Per. A laser microprobe mass analysis of brain aluminum and iron in dementia pugilistica: comparison with Alzheimer's disease. European neurology. vol 38. issue 1. 1997-10-15. PMID:9252800. |
we report a laser microprobe mass analysis of aluminum and iron content in the hippocampus and in the inferior temporal cortex in 2 cases of dementia pugilistica (dp), 4 cases of alzheimer's disease (ad), and 3 controls. |
1997-10-15 |
2023-08-12 |
Not clear |
| D P Huynh, H V Vinters, D H Ho, V V Ho, S M Puls. Neuronal expression and intracellular localization of presenilins in normal and Alzheimer disease brains. Journal of neuropathology and experimental neurology. vol 56. issue 9. 1997-10-15. PMID:9291942. |
immunohistochemical studies of human temporal lobes from 2 normal and 5 sporadic alzheimer brains revealed high levels of ps1 and ps2 expression in the granule cell layer and pyramidal neurons of the hippocampus. |
1997-10-15 |
2023-08-12 |
human |
| M D Ikonomovic, K Mizukami, P Davies, R Hamilton, R Sheffield, D M Armstron. The loss of GluR2(3) immunoreactivity precedes neurofibrillary tangle formation in the entorhinal cortex and hippocampus of Alzheimer brains. Journal of neuropathology and experimental neurology. vol 56. issue 9. 1997-10-15. PMID:9291943. |
the loss of glur2(3) immunoreactivity precedes neurofibrillary tangle formation in the entorhinal cortex and hippocampus of alzheimer brains. |
1997-10-15 |
2023-08-12 |
Not clear |