| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Ishii, M Sasaki, S Yamaji, S Sakamoto, H Kitagaki, E Mor. Paradoxical hippocampus perfusion in mild-to-moderate Alzheimer's disease. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 39. issue 2. 1998-03-12. PMID:9476938. |
the purpose of this study was to clarify the changes in hippocampal perfusion in mild-to-moderate alzheimer's disease using pet and (15)o-labeled water. |
1998-03-12 |
2023-08-12 |
Not clear |
| C Zarow, J Victorof. Increased apolipoprotein E mRNA in the hippocampus in Alzheimer disease and in rats after entorhinal cortex lesioning. Experimental neurology. vol 149. issue 1. 1998-03-06. PMID:9454617. |
increased apolipoprotein e mrna in the hippocampus in alzheimer disease and in rats after entorhinal cortex lesioning. |
1998-03-06 |
2023-08-12 |
rat |
| C Zarow, J Victorof. Increased apolipoprotein E mRNA in the hippocampus in Alzheimer disease and in rats after entorhinal cortex lesioning. Experimental neurology. vol 149. issue 1. 1998-03-06. PMID:9454617. |
the distribution of apolipoprotein e (apoe) mrna was characterized in the hippocampus of humans with alzheimer disease (ad) and in rats with experimental lesions (unilateral ablation of the entorhinal cortex) that model selected features of ad. |
1998-03-06 |
2023-08-12 |
rat |
| Z S Nagy, M M Esir. Apoptosis-related protein expression in the hippocampus in Alzheimer's disease. Neurobiology of aging. vol 18. issue 6. 1998-03-05. PMID:9461054. |
apoptosis-related protein expression in the hippocampus in alzheimer's disease. |
1998-03-05 |
2023-08-12 |
Not clear |
| D J Eve, A P Nisbet, A E Kingsbury, J Temlett, C D Marsden, O J Foste. Selective increase in somatostatin mRNA expression in human basal ganglia in Parkinson's disease. Brain research. Molecular brain research. vol 50. issue 1-2. 1998-02-19. PMID:9406918. |
levels of the neurotransmitter somatostatin (ss) have previously been shown to be reduced in the cortex and hippocampus of demented parkinsonian patients and patients with alzheimer's disease. |
1998-02-19 |
2023-08-12 |
human |
| L A Passani, J P Vonsattel, J T Coyl. Distribution of N-acetylaspartylglutamate immunoreactivity in human brain and its alteration in neurodegenerative disease. Brain research. vol 772. issue 1-2. 1998-02-19. PMID:9406950. |
immunohistochemistry with an antibody against naag was performed on control, huntington's disease (hd) and alzheimer's disease (ad) human autopsy and biopsy brain sections from the cerebral cortex, hippocampus, amygdala, neostriatum, brainstem and spinal cord. |
1998-02-19 |
2023-08-12 |
human |
| B Connor, D Young, Q Yan, R L Faull, B Synek, M Draguno. Brain-derived neurotrophic factor is reduced in Alzheimer's disease. Brain research. Molecular brain research. vol 49. issue 1-2. 1998-02-11. PMID:9387865. |
we observed a reduction in the intensity and number of bdnf-immunoreactive cell bodies within both the alzheimer's disease hippocampus and temporal cortex when compared to normal tissue. |
1998-02-11 |
2023-08-12 |
human |
| B Connor, D Young, Q Yan, R L Faull, B Synek, M Draguno. Brain-derived neurotrophic factor is reduced in Alzheimer's disease. Brain research. Molecular brain research. vol 49. issue 1-2. 1998-02-11. PMID:9387865. |
these results support and extend previous findings that bdnf mrna is reduced in the human alzheimer's disease hippocampus and temporal cortex, and suggest that a loss of bdnf may contribute to the progressive atrophy of neurons in alzheimer's disease. |
1998-02-11 |
2023-08-12 |
human |
| B Connor, E J Beilharz, C Williams, B Synek, P D Gluckman, R L Faull, M Draguno. Insulin-like growth factor-I (IGF-I) immunoreactivity in the Alzheimer's disease temporal cortex and hippocampus. Brain research. Molecular brain research. vol 49. issue 1-2. 1998-02-11. PMID:9387889. |
insulin-like growth factor-i (igf-i) immunoreactivity in the alzheimer's disease temporal cortex and hippocampus. |
1998-02-11 |
2023-08-12 |
human |
| B Connor, E J Beilharz, C Williams, B Synek, P D Gluckman, R L Faull, M Draguno. Insulin-like growth factor-I (IGF-I) immunoreactivity in the Alzheimer's disease temporal cortex and hippocampus. Brain research. Molecular brain research. vol 49. issue 1-2. 1998-02-11. PMID:9387889. |
igf-i immunoreactivity was examined in the alzheimer's disease and normal post-mortem human hippocampus and temporal cortex to determine whether igf-i protein levels are altered in response to neurodegeneration. |
1998-02-11 |
2023-08-12 |
human |
| I J Torres, L A Flashman, D S O'Leary, V Swayze, N C Andrease. Lack of an association between delayed memory and hippocampal and temporal lobe size in patients with schizophrenia and healthy controls. Biological psychiatry. vol 42. issue 12. 1998-02-10. PMID:9426878. |
the integration of results from this study, and from studies on normal aging and alzheimer's disease, supports a model suggesting that hippocampal size may be an indicator of long-term memory ability, but only when hippocampal measures reflect aging and degenerative hippocampal atrophy. |
1998-02-10 |
2023-08-12 |
Not clear |
| H Tohgi, S Takahashi, E Kato, A Homma, R Niina, K Sasaki, H Yonezawa, M Sasak. Reduced size of right hippocampus in 39- to 80-year-old normal subjects carrying the apolipoprotein E epsilon4 allele. Neuroscience letters. vol 236. issue 1. 1998-01-29. PMID:9404942. |
these results suggest that as early as their forties, apo e epsilon4 allele carriers have a markedly smaller right hippocampus with no apparent cognitive impairment, which may have some significance in the high prevalence of the epsilon4 allele in alzheimer's disease as well as other conditions that cause dementia. |
1998-01-29 |
2023-08-12 |
human |
| N Schuff, D Amend, F Ezekiel, S K Steinman, J Tanabe, D Norman, W Jagust, J H Kramer, J A Mastrianni, G Fein, M W Weine. Changes of hippocampal N-acetyl aspartate and volume in Alzheimer's disease. A proton MR spectroscopic imaging and MRI study. Neurology. vol 49. issue 6. 1998-01-16. PMID:9409338. |
changes of hippocampal n-acetyl aspartate and volume in alzheimer's disease. |
1998-01-16 |
2023-08-12 |
human |
| N Schuff, D Amend, F Ezekiel, S K Steinman, J Tanabe, D Norman, W Jagust, J H Kramer, J A Mastrianni, G Fein, M W Weine. Changes of hippocampal N-acetyl aspartate and volume in Alzheimer's disease. A proton MR spectroscopic imaging and MRI study. Neurology. vol 49. issue 6. 1998-01-16. PMID:9409338. |
hippocampal atrophy detected by mri is a prominent feature of early alzheimer's disease (ad), but it is likely that mri underestimates the degree of hippocampal neuron loss, because reactive gliosis attenuates atrophy. |
1998-01-16 |
2023-08-12 |
human |
| A Churchyard, A J Lee. The relationship between dementia and direct involvement of the hippocampus and amygdala in Parkinson's disease. Neurology. vol 49. issue 6. 1998-01-16. PMID:9409348. |
in a clinicopathologic study, we correlated mini-mental state examination scores and dsm-iii dementia ratings with the density of lewy bodies, lewy neurites, neurofibrillary tangles, neuritic plaques, gliosis, and neurons in the hippocampus and amygdala of 27 pd patients without alzheimer's disease changes. |
1998-01-16 |
2023-08-12 |
Not clear |
| P Giannakopoulos, P R Hof, J P Michel, J Guimon, C Boura. Cerebral cortex pathology in aging and Alzheimer's disease: a quantitative survey of large hospital-based geriatric and psychiatric cohorts. Brain research. Brain research reviews. vol 25. issue 2. 1998-01-15. PMID:9403139. |
extensive hippocampal alterations are correlated with age-associated memory impairment, whereas substantial neurofibrillary tangle formation in neocortical association areas of the temporal lobe is a prerequisite for the development of alzheimer's disease. |
1998-01-15 |
2023-08-12 |
human |
| M R Roberson, L E Harrel. Cholinergic activity and amyloid precursor protein metabolism. Brain research. Brain research reviews. vol 25. issue 1. 1998-01-09. PMID:9370050. |
the correlation between plaques and tangles and dementia is not absolute, but a consistent feature of alzheimer's disease is loss of cortical and hippocampal cholinergic function as a result of basal forebrain compromise. |
1998-01-09 |
2023-08-12 |
Not clear |
| A I Kiktenko, N A Uranova, D V Deniso. Quantitative characteristics of changes in synaptic contacts in the hippocampus in Alzheimer's disease. Neuroscience and behavioral physiology. vol 27. issue 6. 1998-01-07. PMID:9406220. |
quantitative characteristics of changes in synaptic contacts in the hippocampus in alzheimer's disease. |
1998-01-07 |
2023-08-12 |
Not clear |
| A Capell, R Saffrich, J C Olivo, L Meyn, J Walter, J Grünberg, P Mathews, R Nixon, C Dotti, C Haas. Cellular expression and proteolytic processing of presenilin proteins is developmentally regulated during neuronal differentiation. Journal of neurochemistry. vol 69. issue 6. 1997-12-12. PMID:9375676. |
we have determined the expression of the alzheimer's disease-associated proteins presenilin-1 and presenilin-2 in primary cultures of rat hippocampal neurons. |
1997-12-12 |
2023-08-12 |
human |
| M Bobinski, J Wegiel, H M Wisniewski, M Tarnawski, M Bobinski, B Reisberg, M J De Leon, D C Mille. Neurofibrillary pathology--correlation with hippocampal formation atrophy in Alzheimer disease. Neurobiology of aging. vol 17. issue 6. 1997-12-04. PMID:9363803. |
the three-dimensionally reconstructed hippocampal formations in three patients with very severe, immobile alzheimer disease (ad) and three age-matched nondemented individuals were examined for a correlation between atrophy of hippocampal formation subdivisions and neurofibrillary changes, neuronal loss, and extent of amyloid deposition in plaques and vessels. |
1997-12-04 |
2023-08-12 |
Not clear |