| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S K Goldsmith, P Wals, I Rozovsky, T E Morgan, C E Finc. Kainic acid and decorticating lesions stimulate the synthesis of C1q protein in adult rat brain. Journal of neurochemistry. vol 68. issue 5. 1997-05-15. PMID:9109531. |
these findings support the hypothesis that the c1q protein detected by immunocytochemistry in senile plaques of alzheimer brains and in the hippocampus after deafferenting lesions is synthesized by resident brain cells. |
1997-05-15 |
2023-08-12 |
rat |
| J A Schneider, R L Watts, M Gearing, R P Brewer, S S Mirr. Corticobasal degeneration: neuropathologic and clinical heterogeneity. Neurology. vol 48. issue 4. 1997-05-15. PMID:9109885. |
six of the 11 cases manifested overlapping neuropathologic features of one or more disorders, including alzheimer's disease (ad), progressive supranuclear palsy (psp), parkinson's disease (pd), and hippocampal sclerosis. |
1997-05-15 |
2023-08-12 |
Not clear |
| A W O'Connell, O Strada, B Earley, B E Leonar. Altered expression of amyloid protein precursor mRNA in the rat hippocampus following trimethyltin intoxication: an in situ hybridization study. Neurochemistry international. vol 30. issue 3. 1997-05-12. PMID:9041563. |
previous studies have reported increased levels of amyloid protein precursor (app) and app mrna in the hippocampus and basal forebrain of patients with alzheimer's disease. |
1997-05-12 |
2023-08-12 |
mouse |
| A J Harding, A Wong, M Svoboda, J J Kril, G M Hallida. Chronic alcohol consumption does not cause hippocampal neuron loss in humans. Hippocampus. vol 7. issue 1. 1997-05-05. PMID:9138671. |
both amnesic (n = 5) and nonamnesic (n = 7) chronic alcoholics were selected and compared with nonalcoholic controls (n = 8) and patients with marked memory loss and hippocampal neurodegeneration caused by alzheimer's disease (n = 4). |
1997-05-05 |
2023-08-12 |
human |
| A J Harding, A Wong, M Svoboda, J J Kril, G M Hallida. Chronic alcohol consumption does not cause hippocampal neuron loss in humans. Hippocampus. vol 7. issue 1. 1997-05-05. PMID:9138671. |
hippocampal volume was significantly reduced in the alcoholics and in patients with alzheimer's disease. |
1997-05-05 |
2023-08-12 |
human |
| A J Harding, A Wong, M Svoboda, J J Kril, G M Hallida. Chronic alcohol consumption does not cause hippocampal neuron loss in humans. Hippocampus. vol 7. issue 1. 1997-05-05. PMID:9138671. |
neuron loss occurred exclusively from the ca1 and subiculum subregions of the hippocampus in alzheimer's disease. |
1997-05-05 |
2023-08-12 |
human |
| C Masullo, G Macch. Resistance of the hippocampus in Creutzfeldt-Jakob disease. Clinical neuropathology. vol 16. issue 1. 1997-05-01. PMID:9020394. |
the results of this study support the view of no close relationships between the demential syndrome typically related to the clinical onset and progression of cjd, and the structural damage of the hippocampus classically involved in the pathogenetic mechanism of the amnestic syndrome related to the clinical presentation and course of more common forms of dementias, such as alzheimer's disease. |
1997-05-01 |
2023-08-12 |
Not clear |
| M Bobinski, J Wegiel, M Tarnawski, M Bobinski, B Reisberg, M J de Leon, D C Miller, H M Wisniewsk. Relationships between regional neuronal loss and neurofibrillary changes in the hippocampal formation and duration and severity of Alzheimer disease. Journal of neuropathology and experimental neurology. vol 56. issue 4. 1997-05-01. PMID:9100672. |
the total numbers of neurons with and without neurofibrillary changes in the hippocampal subdivisions were estimated in 16 subjects with alzheimer disease (ad) and in 5 normal elderly controls. |
1997-05-01 |
2023-08-12 |
human |
| R A Armstrong, N J Cairns, P L Lanto. Dementia with Lewy bodies: clustering of Lewy bodies in human patients. Neuroscience letters. vol 224. issue 1. 1997-05-01. PMID:9132686. |
a regular pattern of lb clusters was observed equally frequently in the cortex and hippocampus, in upper and lower cortical laminae and in 'pure' cases of dlb with negligible alzheimer's disease (ad) pathology compared with cases of ad with dlb. |
1997-05-01 |
2023-08-12 |
human |
| G P Lim, M J Russell, M J Cullen, Z A Töké. Matrix metalloproteinases in dog brains exhibiting Alzheimer-like characteristics. Journal of neurochemistry. vol 68. issue 4. 1997-04-28. PMID:9084432. |
the observations document that changes in mmp-9 expression in amyloid-positive beagle brains are similar to those reported in the human alzheimer's disease hippocampus and suggest the possibility that insufficient activation of mmp-9 may contribute to beta-amyloid accumulation, a hypothesis that needs to be further investigated. |
1997-04-28 |
2023-08-12 |
human |
| D M Man. Pyramidal nerve cell loss in Alzheimer's disease. Neurodegeneration : a journal for neurodegenerative disorders, neuroprotection, and neuroregeneration. vol 5. issue 4. 1997-04-24. PMID:9117557. |
loss of the large pyramidal cells of the association neocortex and hippocampus, along with plaques and tangles, is fundamental to the neuropathology of alzheimer's disease. |
1997-04-24 |
2023-08-12 |
human |
| T C Yasha, L Shankar, V Santosh, S Das, S K Shanka. Histopathological & immunohistochemical evaluation of ageing changes in normal human brain. The Indian journal of medical research. vol 105. 1997-04-24. PMID:9119421. |
in contrast, in the three cases of alzheimer's disease (symbol: see text) ad studied, the nfts and sps were found in high density in both hippocampus and frontal cortex. |
1997-04-24 |
2023-08-12 |
human |
| D A Willoughby, I Rozovsky, A C Lo, C E Finc. Beta-amyloid precursor protein (APP) and APP-RNA are rapidly affected by glutamate in cultured neurons: selective increase of mRNAs encoding a Kunitz protease inhibitor domain. Journal of molecular neuroscience : MN. vol 6. issue 4. 1997-04-23. PMID:8860237. |
previously, we showed that kpi (+) app rna, but not kpi (-) app rna, is upregulated in response to experimental lesions in which neurotoxicity is dependent on nmda receptor activation and in alzheimer's disease hippocampus. |
1997-04-23 |
2023-08-12 |
mouse |
| Kim S Graham, John R Hodge. Differentiating the roles of the hippocampal complex and the neocortex in long-term memory storage: evidence from the study of semantic dementia and Alzheimer's disease. Neuropsychology. vol 11. issue 1. 1997-04-11. PMID:9055272. |
differentiating the roles of the hippocampal complex and the neocortex in long-term memory storage: evidence from the study of semantic dementia and alzheimer's disease. |
1997-04-11 |
2023-08-12 |
Not clear |
| S F Boulay, V K Sood, M R Rayeq, B R Zeeberg, W C Eckelma. Autoradiographic evidence that (R)-3-quinuclidinyl (S)-4-fluoromethylbenzilate ((R,S)-FMeQNB) displays in vivo selectivity for the muscarinic m2 subtype. Nuclear medicine and biology. vol 23. issue 7. 1997-04-10. PMID:8971856. |
alzheimer's disease (ad) involves selective loss of muscarinic m2, but not m1, subtype neuroreceptors in cortical and hippocampal regions of the human brain. |
1997-04-10 |
2023-08-12 |
human |
| E L Helkala, T Hänninen, M Hallikainen, M Könönen, M P Laakso, P Hartikainen, H Soininen, J Partanen, K Partanen, P Vainio, P Riekkine. Slow-wave activity in the spectral analysis of the electroencephalogram and volumes of hippocampus in subgroups of Alzheimer's disease patients. Behavioral neuroscience. vol 110. issue 6. 1997-04-08. PMID:8986328. |
slow-wave activity in the spectral analysis of the electroencephalogram and volumes of hippocampus in subgroups of alzheimer's disease patients. |
1997-04-08 |
2023-08-12 |
Not clear |
| P Mohanakrishnan, A H Fowler, J P Vonsattel, P R Jolles, M M Husain, P Liem, L Myers, R A Komorosk. Regional metabolic alterations in Alzheimer's disease: an in vitro 1H NMR study of the hippocampus and cerebellum. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 52. issue 2. 1997-04-08. PMID:9060968. |
regional metabolic alterations in alzheimer's disease: an in vitro 1h nmr study of the hippocampus and cerebellum. |
1997-04-08 |
2023-08-12 |
Not clear |
| P Mohanakrishnan, A H Fowler, J P Vonsattel, P R Jolles, M M Husain, P Liem, L Myers, R A Komorosk. Regional metabolic alterations in Alzheimer's disease: an in vitro 1H NMR study of the hippocampus and cerebellum. The journals of gerontology. Series A, Biological sciences and medical sciences. vol 52. issue 2. 1997-04-08. PMID:9060968. |
the concentrations of selected metabolites in the hippocampus and cerebellum of 13 alzheimer's diseased (ad) and four nondemented postmortem brains were measured using high resolution 1h nmr spectroscopy. |
1997-04-08 |
2023-08-12 |
Not clear |
| R Rodríguez-Puertas, S Nilsson, J Pascual, A Pazos, T Hökfel. 125I-galanin binding sites in Alzheimer's disease: increases in hippocampal subfields and a decrease in the caudate nucleus. Journal of neurochemistry. vol 68. issue 3. 1997-04-07. PMID:9048756. |
125i-galanin binding sites in alzheimer's disease: increases in hippocampal subfields and a decrease in the caudate nucleus. |
1997-04-07 |
2023-08-12 |
human |
| R Rodríguez-Puertas, S Nilsson, J Pascual, A Pazos, T Hökfel. 125I-galanin binding sites in Alzheimer's disease: increases in hippocampal subfields and a decrease in the caudate nucleus. Journal of neurochemistry. vol 68. issue 3. 1997-04-07. PMID:9048756. |
using iodinated human galanin and autoradiography, galanin binding sites were studied in cortical and hippocampal areas and in some brainstem nuclei in the brains of eight patients with senile dementia of the alzheimer type (sdat) and of nine matched control cases. |
1997-04-07 |
2023-08-12 |
human |