| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G P Reynolds, S L Mason, A Meldrum, S De Keczer, H Parnes, R M Eglen, E H Won. 5-Hydroxytryptamine (5-HT)4 receptors in post mortem human brain tissue: distribution, pharmacology and effects of neurodegenerative diseases. British journal of pharmacology. vol 114. issue 5. 1995-07-14. PMID:7780656. |
in huntington's disease, there was a significant decrease in putamen (control 5.33 +/- 1.08, patient 2.68 +/- 1.08), while in alzheimer's disease, there was a marked loss of receptors in hippocampus (control 2.34 +/- 0.62, patient 0.78 +/- 0.61), in frontal cortex (control,1.76 +/- 0.19, patient 1.30 +/- 0.22). |
1995-07-14 |
2023-08-12 |
human |
| G P Reynolds, S L Mason, A Meldrum, S De Keczer, H Parnes, R M Eglen, E H Won. 5-Hydroxytryptamine (5-HT)4 receptors in post mortem human brain tissue: distribution, pharmacology and effects of neurodegenerative diseases. British journal of pharmacology. vol 114. issue 5. 1995-07-14. PMID:7780656. |
the marked loss of receptors in hippocampal and cortical regions in the brains from patients with alzheimer's disease is consistent with a role for the 5-ht4 receptor in cognitive processing. |
1995-07-14 |
2023-08-12 |
human |
| M Hatzinger, A Z'Brun, U Hemmeter, E Seifritz, F Baumann, E Holsboer-Trachsler, I J Heuse. Hypothalamic-pituitary-adrenal system function in patients with Alzheimer's disease. Neurobiology of aging. vol 16. issue 2. 1995-07-12. PMID:7777138. |
the neuropathologic hallmarks of alzheimer's disease (ad) are very prominent in the hippocampus, a brain site which is pivotal for the regulation of the hypothalamic-pituitary-adrenal (hpa) system. |
1995-07-12 |
2023-08-12 |
human |
| A I Kiktenko, N A Uranova, D D Orlovskai. [Mossy fibers of the hippocampus in Alzheimer's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 95. issue 1. 1995-07-07. PMID:7778393. |
[mossy fibers of the hippocampus in alzheimer's disease]. |
1995-07-07 |
2023-08-12 |
Not clear |
| A I Kiktenko, N A Uranova, D D Orlovskai. [Mossy fibers of the hippocampus in Alzheimer's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 95. issue 1. 1995-07-07. PMID:7778393. |
an ultrastructural study of changes in synaptic contacts and astrocytic processes of postmortem hippocampus was performed in 5 cases of alzheimer's disease. |
1995-07-07 |
2023-08-12 |
Not clear |
| M J West, P D Coleman, D G Flood, J C Troncos. [Differential neuronal loss in the hippocampus in normal aging and in patients with Alzheimer disease]. Ugeskrift for laeger. vol 157. issue 22. 1995-07-06. PMID:7770982. |
[differential neuronal loss in the hippocampus in normal aging and in patients with alzheimer disease]. |
1995-07-06 |
2023-08-12 |
human |
| M J West, P D Coleman, D G Flood, J C Troncos. [Differential neuronal loss in the hippocampus in normal aging and in patients with Alzheimer disease]. Ugeskrift for laeger. vol 157. issue 22. 1995-07-06. PMID:7770982. |
in this report, we describe differences in the regional patterns of neuronal loss, in the hippocampal region of the brains of alzheimer's patients and normal ageing subjects, that indicate that alzheimer's disease is not the manifestation of accelerated ageing, but the expression of a distinct pathological process. |
1995-07-06 |
2023-08-12 |
human |
| K Zilles, M Qü, A Schleicher, M Schroeter, M Kraemer, O W Witt. Plasticity and neurotransmitter receptor changes in Alzheimer's disease and experimental cortical infarcts. Arzneimittel-Forschung. vol 45. issue 3A. 1995-06-29. PMID:7763327. |
since neurotransmission depends on transmitters and their receptors, the densities of transmitter receptors in the hippocampus, parietal association and premotor cortices in alzheimer's disease were measured with quantitative receptor autoradiography. |
1995-06-29 |
2023-08-12 |
Not clear |
| R E Davis, P D Doyle, R T Carroll, M R Emmerling, J Jae. Cholinergic therapies for Alzheimer's disease. Palliative or disease altering? Arzneimittel-Forschung. vol 45. issue 3A. 1995-06-29. PMID:7763338. |
loss of cholinergic function in the neocortex and hippocampus arising from death or atrophy of basal forebrain cholinergic neurons is a consistent feature of the alzheimer brain at autopsy or biopsy. |
1995-06-29 |
2023-08-12 |
human |
| M J de Leon, A Convit, S DeSanti, J Golomb, C Tarshish, H Rusinek, M Bobinski, C Ince, D C Miller, H M Wisniewsk. The hippocampus in aging and Alzheimer's disease. Neuroimaging clinics of North America. vol 5. issue 1. 1995-06-15. PMID:7743078. |
the hippocampus in aging and alzheimer's disease. |
1995-06-15 |
2023-08-12 |
Not clear |
| M J de Leon, A Convit, S DeSanti, J Golomb, C Tarshish, H Rusinek, M Bobinski, C Ince, D C Miller, H M Wisniewsk. The hippocampus in aging and Alzheimer's disease. Neuroimaging clinics of North America. vol 5. issue 1. 1995-06-15. PMID:7743078. |
atrophic changes dominate in the hippocampal region on alzheimer's disease versus the anterior, frontal, and temporal lobes in pick's disease. |
1995-06-15 |
2023-08-12 |
Not clear |
| B Deweer, S Lehéricy, B Pillon, M Baulac, J Chiras, C Marsault, Y Agid, B Duboi. Memory disorders in probable Alzheimer's disease: the role of hippocampal atrophy as shown with MRI. Journal of neurology, neurosurgery, and psychiatry. vol 58. issue 5. 1995-06-15. PMID:7745409. |
memory disorders in probable alzheimer's disease: the role of hippocampal atrophy as shown with mri. |
1995-06-15 |
2023-08-12 |
Not clear |
| A M Kazee, L Y Ha. Cortical Lewy bodies in Alzheimer's disease. Archives of pathology & laboratory medicine. vol 119. issue 5. 1995-06-15. PMID:7748074. |
among alzheimer's disease patients, there was no association of clbs with either senile plaques or neurons containing neurofibrillary tangles in hippocampus, neocortex, or ventral striatum. |
1995-06-15 |
2023-08-12 |
Not clear |
| R Duelli, H Schröck, W Kuschinsky, S Hoye. Intracerebroventricular injection of streptozotocin induces discrete local changes in cerebral glucose utilization in rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 12. issue 8. 1995-06-14. PMID:7747600. |
the decrease in cerebral glucose utilization observed in cortical and hippocampal areas in the present study may correspond to changes in morphobiological parameters which have been found in patients with alzheimer's disease. |
1995-06-14 |
2023-08-12 |
rat |
| S K Goldsmith, J N Joyc. Alterations in hippocampal mossy fiber pathway in schizophrenia and Alzheimer's disease. Biological psychiatry. vol 37. issue 2. 1995-05-19. PMID:7718676. |
alterations in hippocampal mossy fiber pathway in schizophrenia and alzheimer's disease. |
1995-05-19 |
2023-08-12 |
Not clear |
| D Langui, A Probst, J Ulric. Alzheimer's changes in non-demented and demented patients: a statistical approach to their relationships. Acta neuropathologica. vol 89. issue 1. 1995-05-10. PMID:7709732. |
the anterior hippocampus and the entorhinal cortex of 167 non-demented individuals (controls) and 22 patients with alzheimer's dementia were investigated. |
1995-05-10 |
2023-08-12 |
Not clear |
| D Jaarsma, L Veenma-van der Duin, J Kor. N-acetylaspartate and N-acetylaspartylglutamate levels in Alzheimer's disease post-mortem brain tissue. Journal of the neurological sciences. vol 127. issue 2. 1995-05-08. PMID:7707082. |
the tissue concentrations of two related amino acid derivatives, n-acetylaspartate (naa) and n-acetylaspartylglutamate (naag) were determined in autopsy hippocampus, amygdala, cerebellar cortex and olfactory bulb of alzheimer's disease patients and age-matched non-demented controls, using reverse-phase hplc and fluorescence detection after precolumn derivatisation with the fluorophore 2-aminoanthracene. |
1995-05-08 |
2023-08-12 |
Not clear |
| D Jaarsma, L Veenma-van der Duin, J Kor. N-acetylaspartate and N-acetylaspartylglutamate levels in Alzheimer's disease post-mortem brain tissue. Journal of the neurological sciences. vol 127. issue 2. 1995-05-08. PMID:7707082. |
in alzheimer's disease, naa and naag concentrations were significantly reduced in the hippocampus (by 38 and 24%) and the amygdala (by 28 and 22%), but not in the olfactory bulb and the cerebellar cortex. |
1995-05-08 |
2023-08-12 |
Not clear |
| O Heinonen, H Soininen, H Sorvari, O Kosunen, L Paljärvi, E Koivisto, P J Riekkine. Loss of synaptophysin-like immunoreactivity in the hippocampal formation is an early phenomenon in Alzheimer's disease. Neuroscience. vol 64. issue 2. 1995-04-28. PMID:7700527. |
the synaptophysin-like immunoreactivity was decreased in the hippocampus and the entorhinal cortex in patients with definite and possible alzheimer's disease but not in multi-infarct dementia patients compared to controls. |
1995-04-28 |
2023-08-12 |
Not clear |
| E K Perry, C M Morris, J A Court, A Cheng, A F Fairbairn, I G McKeith, D Irving, A Brown, R H Perr. Alteration in nicotine binding sites in Parkinson's disease, Lewy body dementia and Alzheimer's disease: possible index of early neuropathology. Neuroscience. vol 64. issue 2. 1995-04-28. PMID:7700528. |
in the hippocampus, binding was decreased around the granular layer in lewy body dementia and alzheimer's disease, although unchanged in the stratum lacunosum moleculare, where binding was relatively higher. |
1995-04-28 |
2023-08-12 |
human |