| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Dournaud, P Cervera-Pierot, E Hirsch, F Javoy-Agid, C Kordon, Y Agid, J Epelbau. Somatostatin messenger RNA-containing neurons in Alzheimer's disease: an in situ hybridization study in hippocampus, parahippocampal cortex and frontal cortex. Neuroscience. vol 61. issue 4. 1995-03-02. PMID:7838375. |
a significantly lower level of expression of somatostatin messenger rna per somatostatinergic cell was observed in the hippocampus of alzheimer's disease patients (-47%, p < 0.05), but not in frontal cortex gray (-17%) and white (-36%) matter and parahippocampal cortex gray (-42%) and white (-29%) matter. |
1995-03-02 |
2023-08-12 |
human |
| T Kimura, T Hisano, H Yoshida, K Ueda, T Miyakaw. Re-evaluation of classic senile plaques by three-dimensional analysis. Journal of neurology. vol 241. issue 10. 1995-02-27. PMID:7836967. |
we evaluated the proportion of classic plaques among all of the senile plaques in four alzheimer brains (frontal, temporal, occipital and hippocampal areas) by the usual method of two-dimensional analysis using a single methenamine silver-stained section and three-dimensional analysis using a set of serial sections. |
1995-02-27 |
2023-08-12 |
Not clear |
| N A Simonian, T Elvhage, A J Czernik, P Greengard, B T Hyma. Calcium/calmodulin-dependent protein kinase II immunostaining is preserved in Alzheimer's disease hippocampal neurons. Brain research. vol 657. issue 1-2. 1995-02-14. PMID:7820630. |
calcium/calmodulin-dependent protein kinase ii immunostaining is preserved in alzheimer's disease hippocampal neurons. |
1995-02-14 |
2023-08-12 |
Not clear |
| L M Bierer, P R Hof, D P Purohit, L Carlin, J Schmeidler, K L Davis, D P Per. Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease. Archives of neurology. vol 52. issue 1. 1995-02-14. PMID:7826280. |
neocortical and hippocampal ratings for neurofibrillary tangles (nfts) and senile plaques (sps) were compared in 70 cases of clinically and neuropathologically confirmed alzheimer's disease. |
1995-02-14 |
2023-08-12 |
Not clear |
| J C Vickers, B M Riederer, R A Marugg, V Buée-Scherrer, L Buée, A Delacourte, J H Morriso. Alterations in neurofilament protein immunoreactivity in human hippocampal neurons related to normal aging and Alzheimer's disease. Neuroscience. vol 62. issue 1. 1995-02-09. PMID:7816192. |
alterations in neurofilament protein immunoreactivity in human hippocampal neurons related to normal aging and alzheimer's disease. |
1995-02-09 |
2023-08-12 |
human |
| J C Vickers, B M Riederer, R A Marugg, V Buée-Scherrer, L Buée, A Delacourte, J H Morriso. Alterations in neurofilament protein immunoreactivity in human hippocampal neurons related to normal aging and Alzheimer's disease. Neuroscience. vol 62. issue 1. 1995-02-09. PMID:7816192. |
the distribution of immunoreactivity for the neurofilament triplet class of intermediate filament proteins was examined in the hippocampus of young, adult and elderly control cases and compared to that of alzheimer's disease cases. |
1995-02-09 |
2023-08-12 |
human |
| J C Vickers, B M Riederer, R A Marugg, V Buée-Scherrer, L Buée, A Delacourte, J H Morriso. Alterations in neurofilament protein immunoreactivity in human hippocampal neurons related to normal aging and Alzheimer's disease. Neuroscience. vol 62. issue 1. 1995-02-09. PMID:7816192. |
immunoblotting demonstrated that there was a proportionately greater amount of the neurofilament triplet subunit proteins in hippocampal tissue from alzheimer's disease cases as compared to controls. |
1995-02-09 |
2023-08-12 |
human |
| J C Vickers, B M Riederer, R A Marugg, V Buée-Scherrer, L Buée, A Delacourte, J H Morriso. Alterations in neurofilament protein immunoreactivity in human hippocampal neurons related to normal aging and Alzheimer's disease. Neuroscience. vol 62. issue 1. 1995-02-09. PMID:7816192. |
the cellular factors affecting hippocampal neurons during aging may be potentiated in alzheimer's disease to result in even higher levels of intracellular neurofilament proteins and the progressive alterations of neurofilaments and other cytoskeletal proteins that finally results in neurofibrillary tangle formation and cellular degeneration. |
1995-02-09 |
2023-08-12 |
human |
| H L Ryoo, J N Joyc. Loss of dopamine D2 receptors varies along the rostrocaudal axis of the hippocampal complex in Alzheimer's disease. The Journal of comparative neurology. vol 348. issue 1. 1995-02-08. PMID:7814686. |
loss of dopamine d2 receptors varies along the rostrocaudal axis of the hippocampal complex in alzheimer's disease. |
1995-02-08 |
2023-08-12 |
Not clear |
| H L Ryoo, J N Joyc. Loss of dopamine D2 receptors varies along the rostrocaudal axis of the hippocampal complex in Alzheimer's disease. The Journal of comparative neurology. vol 348. issue 1. 1995-02-08. PMID:7814686. |
we report here that alzheimer's disease (ad) is associated with reduced expression of the dopamine d2 receptor, but the effects differ with respect to the rostrocaudal axis and area within the hippocampal complex. |
1995-02-08 |
2023-08-12 |
Not clear |
| J J Pei, E Sersen, K Iqbal, I Grundke-Iqba. Expression of protein phosphatases (PP-1, PP-2A, PP-2B and PTP-1B) and protein kinases (MAP kinase and P34cdc2) in the hippocampus of patients with Alzheimer disease and normal aged individuals. Brain research. vol 655. issue 1-2. 1995-02-06. PMID:7812792. |
expression of protein phosphatases (pp-1, pp-2a, pp-2b and ptp-1b) and protein kinases (map kinase and p34cdc2) in the hippocampus of patients with alzheimer disease and normal aged individuals. |
1995-02-06 |
2023-08-12 |
Not clear |
| N Jetté, M S Cole, M Fahnestoc. NGF mRNA is not decreased in frontal cortex from Alzheimer's disease patients. Brain research. Molecular brain research. vol 25. issue 3-4. 1995-02-02. PMID:7808223. |
alzheimer's disease (ad) is characterized by neuronal dysfunction and degeneration in certain brain regions such as cortex, hippocampus and basal forebrain. |
1995-02-02 |
2023-08-12 |
human |
| R Lathe, R G Morri. Analysing brain function and dysfunction in transgenic animals. Neuropathology and applied neurobiology. vol 20. issue 4. 1995-02-02. PMID:7808585. |
we and others have therefore focused on the hippocampus, a brain region involved in learning and memory and an early target for degeneration in alzheimer's disease. |
1995-02-02 |
2023-08-12 |
Not clear |
| M L Boatell, G Bendahan, N Mah. Time-related cortical amino acid changes after basal forebrain lesion: a microdialysis study. Journal of neurochemistry. vol 64. issue 1. 1995-01-24. PMID:7798924. |
cholinergic basal forebrain (bf) lesions in experimental animals have been used as a potential model for cholinergic deficits in cortex and hippocampus that occur in normal aging and alzheimer's disease (ad). |
1995-01-24 |
2023-08-12 |
rat |
| G Waldemar, P Christiansen, H B Larsson, P Høgh, H Laursen, N A Lassen, O B Paulso. White matter magnetic resonance hyperintensities in dementia of the Alzheimer type: morphological and regional cerebral blood flow correlates. Journal of neurology, neurosurgery, and psychiatry. vol 57. issue 12. 1995-01-23. PMID:7798973. |
in the group of patients with alzheimer's disease as a whole, the volume of dwmhs correlated well with rcbf in the hippocampal region ( r = -0.72; p < 0.001), but not with frontal, temporal, parietal, or occipital rcbf. |
1995-01-23 |
2023-08-12 |
human |
| R Hellweg, M Jockers-Scherüb. Neurotrophic factors in memory disorders. Life sciences. vol 55. issue 25-26. 1995-01-18. PMID:7997075. |
bdnf-mrna levels are reported to be decreased in the hippocampus of individuals with alzheimer's disease (ad). |
1995-01-18 |
2023-08-12 |
human |
| H Jeltsch, J C Cassel, R Jackisch, B Neufang, P L Greene, C Kelche, G Hertting, B Wil. Lesions of supracallosal or infracallosal hippocampal pathways in the rat: behavioral, neurochemical, and histochemical effects. Behavioral and neural biology. vol 62. issue 2. 1995-01-09. PMID:7993302. |
since the behavioral and neurochemical deficits were found to be lasting, it is suggested that bilateral infracallosal damage to the septohippocampal pathways might constitute an interesting paradigm of partial hippocampal deafferentation to investigate the effects of neural grafts or other treatments in an animal model of alzheimer's disease. |
1995-01-09 |
2023-08-12 |
rat |
| W Samuel, E Masliah, L R Hill, N Butters, R Terr. Hippocampal connectivity and Alzheimer's dementia: effects of synapse loss and tangle frequency in a two-component model. Neurology. vol 44. issue 11. 1994-12-20. PMID:7969963. |
hippocampal connectivity and alzheimer's dementia: effects of synapse loss and tangle frequency in a two-component model. |
1994-12-20 |
2023-08-12 |
Not clear |
| A Stojanovic, A E Roher, M J Bal. Quantitative analysis of lipofuscin and neurofibrillary tangles in the hippocampal neurons of Alzheimer disease brains. Dementia (Basel, Switzerland). vol 5. issue 5. 1994-12-13. PMID:7951677. |
quantitative analysis of lipofuscin and neurofibrillary tangles in the hippocampal neurons of alzheimer disease brains. |
1994-12-13 |
2023-08-12 |
Not clear |
| Z X She. Acetylcholinesterase provides deeper insights into Alzheimer's disease. Medical hypotheses. vol 43. issue 1. 1994-12-07. PMID:7968717. |
this article reviews the considerable evidence which rejects the cholinergic hypothesis of alzheimer's disease (ad) and proposes that it is the ache system of which the lightly stained neurons are located in the entorhinal cortex, the ca1/subiculum of the hippocampus and the amygdala which are the most vulnerable and are the earliest affected in the pathological processes of ad. |
1994-12-07 |
2023-08-12 |
Not clear |