| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Hanyu, T Asano, S Sakamoto, D Kogure, T Iwamoto, M Takasak. [Is hippocampal atrophy a specific change for Alzheimer's disease?]. No to shinkei = Brain and nerve. vol 51. issue 11. 2000-01-27. PMID:10586410. |
[is hippocampal atrophy a specific change for alzheimer's disease?]. |
2000-01-27 |
2023-08-12 |
human |
| H Hanyu, T Asano, S Sakamoto, D Kogure, T Iwamoto, M Takasak. [Is hippocampal atrophy a specific change for Alzheimer's disease?]. No to shinkei = Brain and nerve. vol 51. issue 11. 2000-01-27. PMID:10586410. |
although detection of hippocampal atrophy has been proposed for the diagnosis of alzheimer's disease (ad), atrophic changes in mri can be found in other dementia diseases. |
2000-01-27 |
2023-08-12 |
human |
| U Beffert, J S Cohn, C Petit-Turcotte, M Tremblay, N Aumont, C Ramassamy, J Davignon, J Poirie. Apolipoprotein E and beta-amyloid levels in the hippocampus and frontal cortex of Alzheimer's disease subjects are disease-related and apolipoprotein E genotype dependent. Brain research. vol 843. issue 1-2. 2000-01-24. PMID:10528114. |
apolipoprotein e and beta-amyloid levels in the hippocampus and frontal cortex of alzheimer's disease subjects are disease-related and apolipoprotein e genotype dependent. |
2000-01-24 |
2023-08-12 |
human |
| M D Ikonomovic, K Mizukami, D Warde, R Sheffield, R Hamilton, R J Wenthold, D M Armstron. Distribution of glutamate receptor subunit NMDAR1 in the hippocampus of normal elderly and patients with Alzheimer's disease. Experimental neurology. vol 160. issue 1. 2000-01-21. PMID:10630204. |
distribution of glutamate receptor subunit nmdar1 in the hippocampus of normal elderly and patients with alzheimer's disease. |
2000-01-21 |
2023-08-12 |
human |
| Z Z Guan, X Zhang, R Ravid, A Nordber. Decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with Alzheimer's disease. Journal of neurochemistry. vol 74. issue 1. 2000-01-18. PMID:10617125. |
decreased protein levels of nicotinic receptor subunits in the hippocampus and temporal cortex of patients with alzheimer's disease. |
2000-01-18 |
2023-08-12 |
human |
| A I Holodny, V N Kornienko, I N Pronin, O V Klimchuk, A E Georg. [The computed and magnetic resonance tomographic anatomy of the normal hippocampal area and in neurosurgical pathology]. Zhurnal voprosy neirokhirurgii imeni N. N. Burdenko. issue 3. 2000-01-13. PMID:10599158. |
hippocampal atrophy accompanied by enlarged phfs is a sign of alzheimer's disease (1081 patients). |
2000-01-13 |
2023-08-12 |
Not clear |
| M Yanagisawa, E Planel, K Ishiguro, S C Fujit. Starvation induces tau hyperphosphorylation in mouse brain: implications for Alzheimer's disease. FEBS letters. vol 461. issue 3. 1999-12-28. PMID:10567721. |
food deprivation of mice for 1 to 3 days progressively enhanced tau hyperphosphorylation in the hippocampus, to a lesser extent in the cerebral cortex, but the effect was least in the cerebellum, in correspondence with the regional selectivity of tauopathy in alzheimer's disease. |
1999-12-28 |
2023-08-12 |
mouse |
| A K Raina, M J Monteiro, A McShea, M A Smit. The role of cell cycle-mediated events in Alzheimer's disease. International journal of experimental pathology. vol 80. issue 2. 1999-12-23. PMID:10469261. |
however, recently, we and others showed that susceptible hippocampal neurones in alzheimer's disease express markers common to cells in various phases of the cell cycle. |
1999-12-23 |
2023-08-12 |
Not clear |
| P J Yao, R Morsch, L M Callahan, P D Colema. Changes in synaptic expression of clathrin assembly protein AP180 in Alzheimer's disease analysed by immunohistochemistry. Neuroscience. vol 94. issue 2. 1999-12-21. PMID:10579202. |
in the hippocampus, cell body ap180 immunoreactivity normally seen in the hilus and the ca3 regions of control brains was completely lost in alzheimer's disease. |
1999-12-21 |
2023-08-12 |
Not clear |
| J Daly, D K Lahiri, G J Kotwa. Examination of the interactions of the amyloid precursor protein carboxyl terminus to intracellular protein: possible role in apoptosis. Progress in neuro-psychopharmacology & biological psychiatry. vol 23. issue 5. 1999-12-02. PMID:10509380. |
the authors examined hippocampal tissue sections from alzheimer's disease (ad) and age-matched normal control patients for a difference in the number of apoptotic nuclei present using an in situ apoptosis detection kit that labels the numerous free dna ends present in apoptotic nuclei. |
1999-12-02 |
2023-08-12 |
human |
| D M Hodgson, A N Taylor, Z Zhang, A Rosenber. Lysosphingomyelin prevents behavioral aberrations and hippocampal neuron loss induced by the metabotropic glutamate receptor agonist quisqualate. Progress in neuro-psychopharmacology & biological psychiatry. vol 23. issue 5. 1999-12-02. PMID:10509381. |
lysosphingomyelin may be of clinical use in allaying progressive group 1 mglur-induced hippocampal cognitive and motor disorders including alzheimer's disease, brain seizure, and stroke. |
1999-12-02 |
2023-08-12 |
rat |
| R Tapia, F Peña, C Aria. Neurotoxic and synaptic effects of okadaic acid, an inhibitor of protein phosphatases. Neurochemical research. vol 24. issue 11. 1999-11-24. PMID:10555783. |
we analyze recent findings demonstrating that the microinjection of oka in rat hippocampus induces neuronal stress, hyperexcitation and neurodegeneration, and discuss their possible relationships to alterations of protein phosphorylation-dephosphorylation observed in alzheimer's disease brain. |
1999-11-24 |
2023-08-12 |
rat |
| D Suvà, I Favre, R Kraftsik, M Esteban, A Lobrinus, J Mikloss. Primary motor cortex involvement in Alzheimer disease. Journal of neuropathology and experimental neurology. vol 58. issue 11. 1999-11-17. PMID:10560655. |
in alzheimer disease (ad) the involvement of entorhinal cortex, hippocampus, and associative cortical areas is well established. |
1999-11-17 |
2023-08-12 |
Not clear |
| A V Yermakova, J Rollins, L M Callahan, J Rogers, M K O'Banio. Cyclooxygenase-1 in human Alzheimer and control brain: quantitative analysis of expression by microglia and CA3 hippocampal neurons. Journal of neuropathology and experimental neurology. vol 58. issue 11. 1999-11-17. PMID:10560656. |
cyclooxygenase-1 in human alzheimer and control brain: quantitative analysis of expression by microglia and ca3 hippocampal neurons. |
1999-11-17 |
2023-08-12 |
human |
| S C Lee, M L Zhao, A Hirano, D W Dickso. Inducible nitric oxide synthase immunoreactivity in the Alzheimer disease hippocampus: association with Hirano bodies, neurofibrillary tangles, and senile plaques. Journal of neuropathology and experimental neurology. vol 58. issue 11. 1999-11-17. PMID:10560659. |
inducible nitric oxide synthase immunoreactivity in the alzheimer disease hippocampus: association with hirano bodies, neurofibrillary tangles, and senile plaques. |
1999-11-17 |
2023-08-12 |
Not clear |
| S C Lee, M L Zhao, A Hirano, D W Dickso. Inducible nitric oxide synthase immunoreactivity in the Alzheimer disease hippocampus: association with Hirano bodies, neurofibrillary tangles, and senile plaques. Journal of neuropathology and experimental neurology. vol 58. issue 11. 1999-11-17. PMID:10560659. |
in this report, we determined the expression of inos by immunocytochemistry in the hippocampus of the alzheimer brains (ad) as well as in young and old normal brains. |
1999-11-17 |
2023-08-12 |
Not clear |
| N Ghoshal, J F Smiley, A J DeMaggio, M F Hoekstra, E J Cochran, L I Binder, J Kure. A new molecular link between the fibrillar and granulovacuolar lesions of Alzheimer's disease. The American journal of pathology. vol 155. issue 4. 1999-11-04. PMID:10514399. |
alzheimer's disease (ad) is a progressive neurodegenerative disorder involving select neurons of the hippocampus, neocortex, and other regions of the brain. |
1999-11-04 |
2023-08-12 |
Not clear |
| T Kosasa, Y Kuriya, K Matsui, Y Yamanish. Effect of donepezil hydrochloride (E2020) on basal concentration of extracellular acetylcholine in the hippocampus of rats. European journal of pharmacology. vol 380. issue 2-3. 1999-11-01. PMID:10513568. |
the effects of oral administration of the centrally acting acetylcholinesterase (ache) inhibitors, donepezil hydrochloride (donepezil: e2020: (+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-indan-1-one monohydrochloride), tacrine (9-amino-1,2,3,4-tetrahydroacridine hydrochloride) and ena-713 (rivastigmine: (s)-n-ethyl-3-[(1-dimethyl-amino)ethyl]-n-methyl-phenylcarbamate hydrogentartrate), which have been developed for the treatment of alzheimer's disease, on the extracellular acetylcholine concentration in the hippocampus of rats were evaluated by using a microdialysis technique without adding cholinesterase inhibitor to the perfusion solution. |
1999-11-01 |
2023-08-12 |
rat |
| O Ghribi, L Lapierre, M Girard, M Ohayon, J Nalbantoglu, G Massicott. Hypoxia-induced loss of synaptic transmission is exacerbated in hippocampal slices of transgenic mice expressing C-terminal fragments of Alzheimer amyloid precursor protein. Hippocampus. vol 9. issue 3. 1999-10-19. PMID:10401636. |
hypoxia-induced loss of synaptic transmission is exacerbated in hippocampal slices of transgenic mice expressing c-terminal fragments of alzheimer amyloid precursor protein. |
1999-10-19 |
2023-08-12 |
mouse |
| M Z Smith, Z Nagy, M M Esir. Cell cycle-related protein expression in vascular dementia and Alzheimer's disease. Neuroscience letters. vol 271. issue 1. 1999-10-19. PMID:10471210. |
in this study we examine the expression patterns of cyclins a, b1, d1 and e in neuronal nuclei in the hippocampus in autopsied healthy elderly individuals, alzheimer's disease patients and subjects suffering from cerebrovascular disease with and without co-existing alzheimer's disease. |
1999-10-19 |
2023-08-12 |
human |