| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Q S Chen, B L Kagan, Y Hirakura, C W Xi. Impairment of hippocampal long-term potentiation by Alzheimer amyloid beta-peptides. Journal of neuroscience research. vol 60. issue 1. 2000-04-12. PMID:10723069. |
impairment of hippocampal long-term potentiation by alzheimer amyloid beta-peptides. |
2000-04-12 |
2023-08-12 |
rat |
| K Kolasa, L E Harrell, D S Parsons, R Power. Densitometric analysis of Galphao protein subunit levels from postmortem Alzheimer disease hippocampal and prefrontal cortical membranes. Alzheimer disease and associated disorders. vol 14. issue 1. 2000-04-04. PMID:10718205. |
densitometric analysis of galphao protein subunit levels from postmortem alzheimer disease hippocampal and prefrontal cortical membranes. |
2000-04-04 |
2023-08-12 |
human |
| K Kolasa, L E Harrell, D S Parsons, R Power. Densitometric analysis of Galphao protein subunit levels from postmortem Alzheimer disease hippocampal and prefrontal cortical membranes. Alzheimer disease and associated disorders. vol 14. issue 1. 2000-04-04. PMID:10718205. |
an immunoblotting method using prefrontal cortical and hippocampal membranes from control and alzheimer disease postmortem brains was employed to detect three subtypes of galphao protein. |
2000-04-04 |
2023-08-12 |
human |
| K Kolasa, L E Harrell, D S Parsons, R Power. Densitometric analysis of Galphao protein subunit levels from postmortem Alzheimer disease hippocampal and prefrontal cortical membranes. Alzheimer disease and associated disorders. vol 14. issue 1. 2000-04-04. PMID:10718205. |
in the alzheimer disease membranes from hippocampus, the density of total galphao and all three subtype forms was not changed significantly when compared with control values. |
2000-04-04 |
2023-08-12 |
human |
| M Ferrini, G Piroli, M Frontera, A Falbo, A Lima, A F De Nicol. Estrogens normalize the hypothalamic-pituitary-adrenal axis response to stress and increase glucocorticoid receptor immuno-reactivity in hippocampus of aging male rats. Neuroendocrinology. vol 69. issue 2. 2000-03-31. PMID:9986926. |
these animal experiments may be important to elucidate the effects of estrogenic on the hippocampal and hpa dysfunction associated with aging and alzheimer's disease in humans. |
2000-03-31 |
2023-08-12 |
rat |
| T A Ala, G O Beh, W H Fre. Pure hippocampal sclerosis: a rare cause of dementia mimicking Alzheimer's disease. Neurology. vol 54. issue 4. 2000-03-29. PMID:10690974. |
pure hippocampal sclerosis: a rare cause of dementia mimicking alzheimer's disease. |
2000-03-29 |
2023-08-12 |
Not clear |
| M Takahashi, E Iseki, K Kosak. Cdk5 and munc-18/p67 co-localization in early stage neurofibrillary tangles-bearing neurons in Alzheimer type dementia brains. Journal of the neurological sciences. vol 172. issue 1. 2000-03-27. PMID:10620662. |
to characterize the relationship between cdk5 and phf-tau, we investigated the localization of cdk5 and its regulator, p67 (munc 18), in the hippocampus and temporal lobes from 12 alzheimer type dementia (atd) patients and 5 controls using immunohistochemical procedures. |
2000-03-27 |
2023-08-12 |
Not clear |
| S Savolainen, M P Laakso, L Paljärvi, I Alafuzoff, H Hurskainen, K Partanen, H Soininen, M Vapalaht. MR imaging of the hippocampus in normal pressure hydrocephalus: correlations with cortical Alzheimer's disease confirmed by pathologic analysis. AJNR. American journal of neuroradiology. vol 21. issue 2. 2000-03-24. PMID:10696032. |
mr imaging of the hippocampus in normal pressure hydrocephalus: correlations with cortical alzheimer's disease confirmed by pathologic analysis. |
2000-03-24 |
2023-08-12 |
Not clear |
| S Savolainen, M P Laakso, L Paljärvi, I Alafuzoff, H Hurskainen, K Partanen, H Soininen, M Vapalaht. MR imaging of the hippocampus in normal pressure hydrocephalus: correlations with cortical Alzheimer's disease confirmed by pathologic analysis. AJNR. American journal of neuroradiology. vol 21. issue 2. 2000-03-24. PMID:10696032. |
mr studies have shown hippocampal atrophy to be a sensitive diagnostic feature of alzheimer's disease (ad). |
2000-03-24 |
2023-08-12 |
Not clear |
| A K Raina, D J Templeton, J C Deak, G Perry, M A Smit. Quinone reductase (NQO1), a sensitive redox indicator, is increased in Alzheimer's disease. Redox report : communications in free radical research. vol 4. issue 1-2. 2000-03-23. PMID:10714272. |
we suspected that increased nqo1 could signal a major shift in redox balance in alzheimer's disease and, in this study, found that nqo1 is localized not only to neurofibrillary tangles but also the cytoplasm of hippocampal neurons. |
2000-03-23 |
2023-08-12 |
Not clear |
| Z Li. [Microtubule-associated protein30 (MAP30) and ubiquitin detected in neurofibrillary tangles of Alzheimer's disease brains]. Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University. vol 23. issue 1. 2000-03-07. PMID:10681783. |
using immunohistochemical technique, the distribution of immunoreactive products of antiubiquitin and map30 in the neurons of hippocampus of alzheimer's disease (ad) brain were studied. |
2000-03-07 |
2023-08-12 |
Not clear |
| M Bobinski, M J de Leon, J Wegiel, S Desanti, A Convit, L A Saint Louis, H Rusinek, H M Wisniewsk. The histological validation of post mortem magnetic resonance imaging-determined hippocampal volume in Alzheimer's disease. Neuroscience. vol 95. issue 3. 2000-03-01. PMID:10670438. |
the histological validation of post mortem magnetic resonance imaging-determined hippocampal volume in alzheimer's disease. |
2000-03-01 |
2023-08-12 |
Not clear |
| D A Butterfield, T Koppal, R Subramaniam, S Yati. Vitamin E as an antioxidant/free radical scavenger against amyloid beta-peptide-induced oxidative stress in neocortical synaptosomal membranes and hippocampal neurons in culture: insights into Alzheimer's disease. Reviews in the neurosciences. vol 10. issue 2. 2000-02-25. PMID:10658956. |
vitamin e as an antioxidant/free radical scavenger against amyloid beta-peptide-induced oxidative stress in neocortical synaptosomal membranes and hippocampal neurons in culture: insights into alzheimer's disease. |
2000-02-25 |
2023-08-12 |
Not clear |
| C Geroldi, M P Laakso, C DeCarli, A Beltramello, A Bianchetti, H Soininen, M Trabucchi, G B Frison. Apolipoprotein E genotype and hippocampal asymmetry in Alzheimer's disease: a volumetric MRI study. Journal of neurology, neurosurgery, and psychiatry. vol 68. issue 1. 2000-02-10. PMID:10601411. |
apolipoprotein e genotype and hippocampal asymmetry in alzheimer's disease: a volumetric mri study. |
2000-02-10 |
2023-08-12 |
Not clear |
| C Geroldi, M P Laakso, C DeCarli, A Beltramello, A Bianchetti, H Soininen, M Trabucchi, G B Frison. Apolipoprotein E genotype and hippocampal asymmetry in Alzheimer's disease: a volumetric MRI study. Journal of neurology, neurosurgery, and psychiatry. vol 68. issue 1. 2000-02-10. PMID:10601411. |
this study evaluated the effect of the apoe genotype on hippocampal asymmetry in patients with alzheimer's disease carrying 0, 1, and 2 copies of the allele. |
2000-02-10 |
2023-08-12 |
Not clear |
| C Geroldi, M P Laakso, C DeCarli, A Beltramello, A Bianchetti, H Soininen, M Trabucchi, G B Frison. Apolipoprotein E genotype and hippocampal asymmetry in Alzheimer's disease: a volumetric MRI study. Journal of neurology, neurosurgery, and psychiatry. vol 68. issue 1. 2000-02-10. PMID:10601411. |
in controls, the right hippocampus was larger than the left, whereas in patients with alzheimer's disease this asymmetry was progressively reduced with increasing gene dose of the epsilon4 allele, and the asymmetry was reversed in the epsilon4/4 alzheimer's disease group. |
2000-02-10 |
2023-08-12 |
Not clear |
| C Geroldi, M P Laakso, C DeCarli, A Beltramello, A Bianchetti, H Soininen, M Trabucchi, G B Frison. Apolipoprotein E genotype and hippocampal asymmetry in Alzheimer's disease: a volumetric MRI study. Journal of neurology, neurosurgery, and psychiatry. vol 68. issue 1. 2000-02-10. PMID:10601411. |
the data indicate a dose dependent effect of the apoe epsilon4 allele on hippocampal volume asymmetry in alzheimer's disease. |
2000-02-10 |
2023-08-12 |
Not clear |
| P H Robert, E Gokalsing, C Bertogliat. [Cholinergic hypothesis and Alzheimer's disease: the place of donepezil (Aricept)]. L'Encephale. vol 25 Spec No 5. 2000-02-08. PMID:10609099. |
one of the earliest pathological events in alzheimer's disease consists in the degeneration of cholinergic neurons in the subcortical regions and, more particularly, in meynert's nucleus basalis which projects, in a topographically organized manner, to the cortical regions and hippocampus. |
2000-02-08 |
2023-08-12 |
Not clear |
| P F Edgar, J E Douglas, C Knight, G J Cooper, R L Faull, R Kyd. Proteome map of the human hippocampus. Hippocampus. vol 9. issue 6. 2000-02-08. PMID:10641757. |
the hippocampus is involved in the processing of short-term memory and is affected in alzheimer's disease. |
2000-02-08 |
2023-08-12 |
human |
| U Soomets, R Mahlapuu, R Tehranian, J Jarvet, E Karelson, M Zilmer, K Iverfeldt, M Zorko, A Gräslund, U Lange. Regulation of GTPase and adenylate cyclase activity by amyloid beta-peptide and its fragments in rat brain tissue. Brain research. vol 850. issue 1-2. 2000-02-03. PMID:10629763. |
modulation of gtpase and adenylate cyclase (atp pyrophosphate-lyase, ec 4.6.1.1) activity by alzheimer's disease related amyloid beta-peptide, a beta (1-42), and its shorter fragments, a beta (12-28), a beta (25-35), were studied in isolated membranes from rat ventral hippocampus and frontal cortex. |
2000-02-03 |
2023-08-12 |
rat |