| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G M Reid, H Tervi. Sudden infant death syndrome: oxidative stress. Medical hypotheses. vol 52. issue 6. 1999-10-12. PMID:10459841. |
sod and neuronal aging and degeneration in the hippocampus and neocortex were features of sids, alzheimer's disease and down's syndrome. |
1999-10-12 |
2023-08-12 |
cat |
| M Kelliher, J Fastbom, R F Cowburn, W Bonkale, T G Ohm, R Ravid, V Sorrentino, C O'Neil. Alterations in the ryanodine receptor calcium release channel correlate with Alzheimer's disease neurofibrillary and beta-amyloid pathologies. Neuroscience. vol 92. issue 2. 1999-09-17. PMID:10408600. |
relationships between ryanodine receptor changes and the progression of alzheimer's disease pathology were determined by examining autoradiographic [3h]ryanodine binding in entorhinal cortex/anterior hippocampus sections from 22 cases that had been staged for neurofibrillary changes and beta-amyloid deposition. |
1999-09-17 |
2023-08-12 |
Not clear |
| H Shinoto. [PET study of cholinergic system in the brain]. Rinsho shinkeigaku = Clinical neurology. vol 39. issue 1. 1999-09-15. PMID:10377794. |
in 11 patients with alzheimer's disease, there was a significant reduction (-24%) of k 3 values in the cerebral cortex and hippocampus, suggesting a loss of ascending cholinergic system from the basal forebrain to the cerebral cortex and hippocampus. |
1999-09-15 |
2023-08-12 |
human |
| b' M Riekkinen, M P Laakso, P J\\xc3\\xa4k\\xc3\\xa4l\\xc3\\xa. Clonidine impairs sustained attention and memory in Alzheimer\'s disease. Neuroscience. vol 92. issue 3. 1999-09-09. PMID:10426537.' |
the volumes of the hippocampus and the entorhinal cortex of those alzheimer's disease patients who were sensitive to clonidine administration were larger than those whose performance was unaffected by clonidine. |
1999-09-09 |
2023-08-12 |
Not clear |
| b' M Riekkinen, M P Laakso, P J\\xc3\\xa4k\\xc3\\xa4l\\xc3\\xa. Clonidine impairs sustained attention and memory in Alzheimer\'s disease. Neuroscience. vol 92. issue 3. 1999-09-09. PMID:10426537.' |
our results suggest that the disruptive effect of clonidine on short-term memory in alzheimer's disease patients may be mediated via the hippocampus and the entorhinal cortex. |
1999-09-09 |
2023-08-12 |
Not clear |
| b' P M Mattila, J O Rinne, H Helenius, M R\\xc3\\xb6ytt\\xc3\\xa. Neuritic degeneration in the hippocampus and amygdala in Parkinson\'s disease in relation to Alzheimer pathology. Acta neuropathologica. vol 98. issue 2. 1999-09-09. PMID:10442555.' |
neuritic degeneration in the hippocampus and amygdala in parkinson's disease in relation to alzheimer pathology. |
1999-09-09 |
2023-08-12 |
Not clear |
| K Meguro, X Blaizot, Y Kondoh, C Le Mestric, J C Baron, C Chavoi. Neocortical and hippocampal glucose hypometabolism following neurotoxic lesions of the entorhinal and perirhinal cortices in the non-human primate as shown by PET. Implications for Alzheimer's disease. Brain : a journal of neurology. vol 122 ( Pt 8). 1999-09-07. PMID:10430835. |
compared with sham-operated baboons, the lesioned animals showed a significant and long-lasting cmr(glc) decline in a small set of brain regions, especially in the inferior parietal, posterior temporal, posterior cingulate and associative occipital cortices, as well as in the posterior hippocampal region, all of which also exhibit glucose hypometabolism in alzheimer's disease. |
1999-09-07 |
2023-08-12 |
Not clear |
| K Meguro, X Blaizot, Y Kondoh, C Le Mestric, J C Baron, C Chavoi. Neocortical and hippocampal glucose hypometabolism following neurotoxic lesions of the entorhinal and perirhinal cortices in the non-human primate as shown by PET. Implications for Alzheimer's disease. Brain : a journal of neurology. vol 122 ( Pt 8). 1999-09-07. PMID:10430835. |
nevertheless, this study shows for the first time that the temporoparietal and hippocampal hypometabolism found in alzheimer's disease may partly result from neuroanatomical disconnection with the rhinal cortex. |
1999-09-07 |
2023-08-12 |
Not clear |
| X Wei, Y Zhang, J Zho. Alzheimer's disease-related gene expression in the brain of senescence accelerated mouse. Neuroscience letters. vol 268. issue 3. 1999-09-01. PMID:10406024. |
the levels of alzheimer's disease (ad)-related genes, including beta-amyloid precursor protein(app), presenilin-1 (ps-1), ps-2, apoe, tau, c-fos, neural cell adhesion molecular 180 (ncam-180), tgf-beta 1, il-1 alpha/beta, il-6, tnf-alpha/beta, alpha-2-macroglobulin (alpha 2m), class ii major histocompatibility antigen la (mhcii la), bcl-2 alpha, glucocorticoid receptor-alpha (gr alpha) and mineralocorticoid receptor (mr) mrnas were determined by reverse transcription polymerase chain reaction (rt-pcr) in the hippocampus and cerebral cortex of senescence accelerated mouse (sam). |
1999-09-01 |
2023-08-12 |
mouse |
| M Y Aksenov, H M Tucker, P Nair, M V Aksenova, D A Butterfield, S Estus, W R Markesber. The expression of several mitochondrial and nuclear genes encoding the subunits of electron transport chain enzyme complexes, cytochrome c oxidase, and NADH dehydrogenase, in different brain regions in Alzheimer's disease. Neurochemical research. vol 24. issue 6. 1999-08-12. PMID:10447460. |
in this study, changes of the expression of two mitochondrial and two nuclear genes encoding the subunits of cytochrome c oxidase (co) and nadh dehydrogenase (nd) were studied in the hippocampus, inferior parietal lobule, and cerebellum of 10 alzheimer's disease (ad) and 10 age-matched control subjects. |
1999-08-12 |
2023-08-12 |
human |
| M Golebiowski, M Barcikowska, A Pfeffe. Magnetic resonance imaging-based hippocampal volumetry in patients with dementia of the Alzheimer type. Dementia and geriatric cognitive disorders. vol 10. issue 4. 1999-08-05. PMID:10364646. |
magnetic resonance imaging-based hippocampal volumetry in patients with dementia of the alzheimer type. |
1999-08-05 |
2023-08-12 |
Not clear |
| M Golebiowski, M Barcikowska, A Pfeffe. Magnetic resonance imaging-based hippocampal volumetry in patients with dementia of the Alzheimer type. Dementia and geriatric cognitive disorders. vol 10. issue 4. 1999-08-05. PMID:10364646. |
the volumetric hippocampal measurements were 39.4% smaller in dementia of the alzheimer type than in controls. |
1999-08-05 |
2023-08-12 |
Not clear |
| P S Harrison, Z Henderso. Quantitative evidence for increase in galanin-immunoreactive terminals in the hippocampal formation following entorhinal cortex lesions in the adult rat. Neuroscience letters. vol 266. issue 1. 1999-08-02. PMID:10336179. |
the projection from the entorhinal cortex to the dentate gyrus and hippocampus is severely affected in alzheimer's disease and there is a depletion of cholinergic terminals but an upregulation of the neuropeptide galanin, which inhibits the release of acetylcholine. |
1999-08-02 |
2023-08-12 |
rat |
| b' I Ferrer, C Mar\\xc3\\xadn, M J Rey, T Ribalta, E Goutan, R Blanco, E Tolosa, E Mart\\xc3\\xa. BDNF and full-length and truncated TrkB expression in Alzheimer disease. Implications in therapeutic strategies. Journal of neuropathology and experimental neurology. vol 58. issue 7. 1999-07-27. PMID:10411343.' |
brain-derived neurotrophic factor (bdnf), and full-length and truncated tyrosin kinase b receptor (trkb) protein expression were examined by western blotting and immunohistochemistry in the frontal cortex and hippocampus of individuals affected by long-lasting severe alzheimer disease (ad) and age-matched controls. |
1999-07-27 |
2023-08-12 |
human |
| I I Kruman, A Nath, W F Maragos, S L Chan, M Jones, V M Rangnekar, R J Jakel, M P Mattso. Evidence that Par-4 participates in the pathogenesis of HIV encephalitis. The American journal of pathology. vol 155. issue 1. 1999-07-26. PMID:10393834. |
we now report that levels of par-4, a protein recently linked to neuronal apoptosis in alzheimer's disease, are increased in neurons in hippocampus of human patients with hiv encephalitis and in monkeys infected with a chimeric strain of hiv-1 and simian immunodeficiency virus. |
1999-07-26 |
2023-08-12 |
human |
| J M Brezun, A Daszut. Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats. Neuroscience. vol 89. issue 4. 1999-07-22. PMID:10362289. |
indeed, lack of 5-hydroxytryptamine in the hippocampus has been associated with cognitive disorders, such as depression, schizophrenia and alzheimer's disease. |
1999-07-22 |
2023-08-12 |
human |
| W Lu, H Tang, M Fan, R Mi, L Wang, J Ji. Research on nucleolar organizer regions of hippocampal neuron in Alzheimer's disease. Chinese medical journal. vol 111. issue 3. 1999-07-20. PMID:10374436. |
research on nucleolar organizer regions of hippocampal neuron in alzheimer's disease. |
1999-07-20 |
2023-08-12 |
Not clear |
| W Lu, H Tang, M Fan, R Mi, L Wang, J Ji. Research on nucleolar organizer regions of hippocampal neuron in Alzheimer's disease. Chinese medical journal. vol 111. issue 3. 1999-07-20. PMID:10374436. |
to understand the cellular genetic expression of the cell's population by studying the nucleolar organizer regions (nors) of hippocampal neuron of alzheimer's disease (ad). |
1999-07-20 |
2023-08-12 |
Not clear |
| P E Lipsk. The clinical potential of cyclooxygenase-2-specific inhibitors. The American journal of medicine. vol 106. issue 5B. 1999-07-08. PMID:10390128. |
further, cox-2 expression may be up-regulated at certain sites: in the kidney during sodium restriction; in the microglia of cognitive centers within the hippocampus and cortex in alzheimer's disease; and in intestinal adenomas and colon tumors. |
1999-07-08 |
2023-08-12 |
human |
| D T Yew, H W Wong, W P Li, H W Lai, W H Y. Nitric oxide synthase neurons in different areas of normal aged and Alzheimer's brains. Neuroscience. vol 89. issue 3. 1999-07-07. PMID:10199604. |
these results show that (i) nitric oxide synthase neurons are abundant in the human cortex, (ii) the distribution of nitric oxide synthase neurons differs between different cortical regions, and (iii) there are differences between normal ageing and alzheimer patients in the frontal cortex and the hippocampus. |
1999-07-07 |
2023-08-12 |
human |