| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Luisa Benerini Gatta, Alberto Albertini, Rivka Ravid, Dario Finazz. Levels of beta-secretase BACE and alpha-secretase ADAM10 mRNAs in Alzheimer hippocampus. Neuroreport. vol 13. issue 16. 2003-04-17. PMID:12438920. |
levels of beta-secretase bace and alpha-secretase adam10 mrnas in alzheimer hippocampus. |
2003-04-17 |
2023-08-12 |
Not clear |
| Mariko Yamashita, Toru Yamamoto, Masahito Yamada, Souichi Okino, Takuji Fujit. [Sporadic cerebral amyloid angiopathy presenting with dementia and prominent capillary beta-amyloid deposition: a case report]. Rinsho shinkeigaku = Clinical neurology. vol 42. issue 6. 2003-04-08. PMID:12607981. |
senile plaques of neuritic type and neurofibrillary tangles were mostly limited to the hippocampal regions and, to a lesser degree, in the amygdaloid nucleus, which did not meet the neuropathological criteria of alzheimer's disease. |
2003-04-08 |
2023-08-12 |
Not clear |
| S Kesavapany, S J Banner, K-F Lau, C E Shaw, C C J Miller, J D Cooper, D M McLoughli. Expression of the Fe65 adapter protein in adult and developing mouse brain. Neuroscience. vol 115. issue 3. 2003-04-07. PMID:12435432. |
the areas of highest expression included regions of the hippocampus in which the earliest abnormalities of alzheimer's disease are detectable. |
2003-04-07 |
2023-08-12 |
mouse |
| David Ramonet, Marco Pugliese, Manuel J Rodríguez, Lluïsa de Yebra, Carmen Andrade, Rosa Adroer, Teresa Ribalta, Joan Mascort, Nicole Mah. Calcium precipitation in acute and chronic brain diseases. Journal of physiology, Paris. vol 96. issue 3-4. 2003-04-04. PMID:12445910. |
to determine if calcification can be viewed as a protective step of calcium homeostasis during chronic and acute neuronal suffering, cerebral cortex and hippocampus of patients with alzheimer's disease, vascular dementia and neonatal hypoxia-ischemia were investigated. |
2003-04-04 |
2023-08-12 |
human |
| Warren W Barker, Cheryl A Luis, Alice Kashuba, Mercy Luis, Dylan G Harwood, David Loewenstein, Carol Waters, Pat Jimison, Eugene Shepherd, Steven Sevush, Neil Graff-Radford, Douglas Newland, Murray Todd, Bayard Miller, Michael Gold, Kenneth Heilman, Leilani Doty, Ira Goodman, Bruce Robinson, Gary Pearl, Dennis Dickson, Ranjan Duar. Relative frequencies of Alzheimer disease, Lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the State of Florida Brain Bank. Alzheimer disease and associated disorders. vol 16. issue 4. 2003-04-01. PMID:12468894. |
relative frequencies of alzheimer disease, lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the state of florida brain bank. |
2003-04-01 |
2023-08-12 |
human |
| Warren W Barker, Cheryl A Luis, Alice Kashuba, Mercy Luis, Dylan G Harwood, David Loewenstein, Carol Waters, Pat Jimison, Eugene Shepherd, Steven Sevush, Neil Graff-Radford, Douglas Newland, Murray Todd, Bayard Miller, Michael Gold, Kenneth Heilman, Leilani Doty, Ira Goodman, Bruce Robinson, Gary Pearl, Dennis Dickson, Ranjan Duar. Relative frequencies of Alzheimer disease, Lewy body, vascular and frontotemporal dementia, and hippocampal sclerosis in the State of Florida Brain Bank. Alzheimer disease and associated disorders. vol 16. issue 4. 2003-04-01. PMID:12468894. |
alzheimer disease (ad) is the most common dementing illness in the elderly, but there is equivocal evidence regarding the frequency of other disorders such as lewy body disease (lbd), vascular dementia (vad), frontotemporal dementia (ftd), and hippocampal sclerosis (hs). |
2003-04-01 |
2023-08-12 |
human |
| I Ferrer, M Barrachina, M Tolnay, M J Rey, N Vidal, M Carmona, R Blanco, B Pui. Phosphorylated protein kinases associated with neuronal and glial tau deposits in argyrophilic grain disease. Brain pathology (Zurich, Switzerland). vol 13. issue 1. 2003-03-31. PMID:12580546. |
a few tangles were observed in the entorhinal cortex and hippocampus corresponding to alzheimer's disease (ad) stages i-iii of braak and braak. |
2003-03-31 |
2023-08-12 |
Not clear |
| Kejal Kantarci, YueCheng Xu, Maria M Shiung, Peter C O'Brien, Ruth H Cha, Glenn E Smith, Robert J Ivnik, Bradley F Boeve, Steven D Edland, Emre Kokmen, Eric G Tangalos, Ronald C Petersen, Clifford R Jac. Comparative diagnostic utility of different MR modalities in mild cognitive impairment and Alzheimer's disease. Dementia and geriatric cognitive disorders. vol 14. issue 4. 2003-03-28. PMID:12411762. |
this study compares the diagnostic accuracy of magnetic resonance (mr)-based hippocampal volumetry, single voxel (1)h mr spectroscopy ((1)h mrs) and mr diffusion-weighted imaging (dwi) measurements in discriminating patients with amnestic mild cognitive impairment (mci), alzheimer's disease (ad) and normally aging elderly. |
2003-03-28 |
2023-08-12 |
Not clear |
| Ezra Mulugeta, Evert Karlsson, Atiqul Islam, Raj Kalaria, Halinder Mangat, Bengt Winblad, Abdu Ade. Loss of muscarinic M4 receptors in hippocampus of Alzheimer patients. Brain research. vol 960. issue 1-2. 2003-03-28. PMID:12505680. |
loss of muscarinic m4 receptors in hippocampus of alzheimer patients. |
2003-03-28 |
2023-08-12 |
Not clear |
| Ezra Mulugeta, Evert Karlsson, Atiqul Islam, Raj Kalaria, Halinder Mangat, Bengt Winblad, Abdu Ade. Loss of muscarinic M4 receptors in hippocampus of Alzheimer patients. Brain research. vol 960. issue 1-2. 2003-03-28. PMID:12505680. |
we assessed muscarinic m(1), m(2) and m(4) receptor subtypes in the hippocampus of alzheimer's and control brains by receptor autoradiography using ligands such as [(125)i]muscarinic toxin-1 ([(125)i]mt-1, m(1) selective), [(3)h]afdx-384 (m(2) partially selective) and [(125)i]muscarinic toxin 4 ([(125)i]m(4) toxin-1, m(4) selective). |
2003-03-28 |
2023-08-12 |
Not clear |
| Hyoung-gon Lee, Xiongwei Zhu, Hossein A Ghanbari, Osamu Ogawa, Arun K Raina, Micheal J O'Neill, George Perry, Mark A Smit. Differential regulation of glutamate receptors in Alzheimer's disease. Neuro-Signals. vol 11. issue 5. 2003-03-27. PMID:12566929. |
specifically, since glutamatergic transmission is severely altered by the early degeneration of cortico-cortical connections and hippocampal projections in alzheimer's disease, we suspect that glutamate receptors may play a new role in the pathophysiology of disease. |
2003-03-27 |
2023-08-12 |
Not clear |
| Rachel C Brown, Zeqiu Han, Caterina Cascio, Vassilios Papadopoulo. Oxidative stress-mediated DHEA formation in Alzheimer's disease pathology. Neurobiology of aging. vol 24. issue 1. 2003-03-26. PMID:12493551. |
to determine if this pathway exists in human brain, levels of dhea in hippocampus, hypothalamus and frontal cortex from alzheimer's disease (ad) patients and age-matched controls were measured. |
2003-03-26 |
2023-08-12 |
human |
| S J Teipel, W Bayer, G E Alexander, A L W Bokde, Y Zebuhr, D Teichberg, F Müller-Spahn, M B Schapiro, H-J Möller, S I Rapoport, H Hampe. Regional pattern of hippocampus and corpus callosum atrophy in Alzheimer's disease in relation to dementia severity: evidence for early neocortical degeneration. Neurobiology of aging. vol 24. issue 1. 2003-03-26. PMID:12493554. |
regional pattern of hippocampus and corpus callosum atrophy in alzheimer's disease in relation to dementia severity: evidence for early neocortical degeneration. |
2003-03-26 |
2023-08-12 |
Not clear |
| T den Heijer, S E Vermeer, R Clarke, M Oudkerk, P J Koudstaal, A Hofman, M M B Bretele. Homocysteine and brain atrophy on MRI of non-demented elderly. Brain : a journal of neurology. vol 126. issue Pt 1. 2003-03-20. PMID:12477704. |
hippocampal, amygdalar and global brain atrophy on brain mri have been proposed as early markers of alzheimer's disease. |
2003-03-20 |
2023-08-12 |
human |
| T den Heijer, S E Vermeer, R Clarke, M Oudkerk, P J Koudstaal, A Hofman, M M B Bretele. Homocysteine and brain atrophy on MRI of non-demented elderly. Brain : a journal of neurology. vol 126. issue Pt 1. 2003-03-20. PMID:12477704. |
these results support the hypothesis that higher plasma homocysteine levels are associated with more atrophy of the hippocampus and cortical regions in elderly at risk of alzheimer's disease. |
2003-03-20 |
2023-08-12 |
human |
| D A Cottrell, G M Borthwick, M A Johnson, P G Ince, D M Turnbul. The role of cytochrome c oxidase deficient hippocampal neurones in Alzheimer's disease. Neuropathology and applied neurobiology. vol 28. issue 5. 2003-03-12. PMID:12366820. |
the role of cytochrome c oxidase deficient hippocampal neurones in alzheimer's disease. |
2003-03-12 |
2023-08-12 |
Not clear |
| Tom den Heijer, Mirjam I Geerlings, Albert Hofman, Frank H de Jong, Lenore J Launer, Huibert A P Pols, Monique M B Bretele. Higher estrogen levels are not associated with larger hippocampi and better memory performance. Archives of neurology. vol 60. issue 2. 2003-03-11. PMID:12580706. |
animal study findings have shown beneficial effects of estrogen on the brain, particularly on the hippocampus, a structure related to memory performance and early alzheimer disease. |
2003-03-11 |
2023-08-12 |
Not clear |
| F Maestú, J Arrazola, A Fernández, P G Simos, C Amo, P Gil-Gregorio, S Fernandez, A Papanicolaou, T Orti. Do cognitive patterns of brain magnetic activity correlate with hippocampal atrophy in Alzheimer's disease? Journal of neurology, neurosurgery, and psychiatry. vol 74. issue 2. 2003-02-26. PMID:12531952. |
do cognitive patterns of brain magnetic activity correlate with hippocampal atrophy in alzheimer's disease? |
2003-02-26 |
2023-08-12 |
Not clear |
| B Laurent, C Thomas Antério. [Limits and uncertainties about the concept of MCI: contribution of neuropsychological approach]. Revue neurologique. vol 158. issue 10 Suppl. 2003-02-21. PMID:12529581. |
cent of mci will remain steady after 5 years of following, and several autopsies of mci have showed that the neuropathological frontier of alzheimer disease were crossed with neurofibrillary tangles and senile plaques in the hippocampus. |
2003-02-21 |
2023-08-12 |
Not clear |
| M Sarazin, B Duboi. [Mild Cognitive Impairment or pre-demential Alzheimer's disease?]. Revue neurologique. vol 158. issue 10 Suppl. 2003-02-21. PMID:12529583. |
the predementia phase of alzheimer's disease is characterized by a progressive "hippocampal" decline in memory, sometimes associated with impaired execution. |
2003-02-21 |
2023-08-12 |
human |