| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Ranga Rama Krishnan, H Cecil Charles, P Murali Doraiswamy, Jacobo Mintzer, Richard Weisler, Xin Yu, Carlos Perdomo, John R Ieni, Sharon Roger. Randomized, placebo-controlled trial of the effects of donepezil on neuronal markers and hippocampal volumes in Alzheimer's disease. The American journal of psychiatry. vol 160. issue 11. 2004-01-29. PMID:14594748. |
randomized, placebo-controlled trial of the effects of donepezil on neuronal markers and hippocampal volumes in alzheimer's disease. |
2004-01-29 |
2023-08-12 |
Not clear |
| Richard Camicioli, M Milar Moore, Anthony Kinney, Elizabeth Corbridge, Kathryn Glassberg, Jeffrey A Kay. Parkinson's disease is associated with hippocampal atrophy. Movement disorders : official journal of the Movement Disorder Society. vol 18. issue 7. 2004-01-28. PMID:12815657. |
we compared hippocampal, and extra-hippocampal volumes between pd, pdd (patients with pd who have mild cognitive impairment or dementia), alzheimer's disease (ad) and controls using volumetric magnetic resonance imaging (mri). |
2004-01-28 |
2023-08-12 |
human |
| Nunzio Pomara, William M Greenberg, Michael D Branford, P Murali Doraiswam. Therapeutic implications of HPA axis abnormalities in Alzheimer's disease: review and update. Psychopharmacology bulletin. vol 37. issue 2. 2004-01-28. PMID:14674372. |
these results are relevant for understanding and treating memory dysfunction in individuals with alzheimer's disease, a disorder prominently and invariably characterized by early hippocampal lesions and memory impairment. |
2004-01-28 |
2023-08-12 |
human |
| M Schumacher, S Weill-Engerer, P Liere, F Robert, R J M Franklin, L M Garcia-Segura, J J Lambert, W Mayo, R C Melcangi, A Parducz, U Suter, C Carelli, E E Baulieu, Y Akw. Steroid hormones and neurosteroids in normal and pathological aging of the nervous system. Progress in neurobiology. vol 71. issue 1. 2004-01-16. PMID:14611864. |
the conversion of dehydroepiandrosterone to delta5-androstene-3beta,17beta-diol and to 7alpha-oh-dehydroepiandrosterone occurred in frontal cortex, hippocampus, amygdala, cerebellum and striatum of both alzheimer's patients and controls. |
2004-01-16 |
2023-08-12 |
human |
| Stephen Schef. Reactive synaptogenesis in aging and Alzheimer's disease: lessons learned in the Cotman laboratory. Neurochemical research. vol 28. issue 11. 2004-01-14. PMID:14584816. |
in alzheimer's disease, one observes a marked reduction in the number of synaptic contacts in important association areas of the cortex and hippocampus. |
2004-01-14 |
2023-08-12 |
Not clear |
| Ester Angulo, Vicent Casadó, Josefa Mallol, Enric I Canela, Francesc Viñals, Isidre Ferrer, Carmen Lluis, Rafael Franc. A1 adenosine receptors accumulate in neurodegenerative structures in Alzheimer disease and mediate both amyloid precursor protein processing and tau phosphorylation and translocation. Brain pathology (Zurich, Switzerland). vol 13. issue 4. 2004-01-12. PMID:14655750. |
immunostaining of adenosine receptors in the hippocampus and cerebral cortex from necropsies of alzheimer disease (ad) patients shows that there is a change in the pattern of expression and a redistribution of receptors in these brain areas when compared with samples from controls. |
2004-01-12 |
2023-08-12 |
human |
| Xiang-You Hu, Song Qin, Ya-Ping Lu, Rivka Ravid, Dick F Swaab, Jiang-Ning Zho. Decreased estrogen receptor-alpha expression in hippocampal neurons in relation to hyperphosphorylated tau in Alzheimer patients. Acta neuropathologica. vol 106. issue 3. 2004-01-09. PMID:12819990. |
decreased estrogen receptor-alpha expression in hippocampal neurons in relation to hyperphosphorylated tau in alzheimer patients. |
2004-01-09 |
2023-08-12 |
Not clear |
| Xiang-You Hu, Song Qin, Ya-Ping Lu, Rivka Ravid, Dick F Swaab, Jiang-Ning Zho. Decreased estrogen receptor-alpha expression in hippocampal neurons in relation to hyperphosphorylated tau in Alzheimer patients. Acta neuropathologica. vol 106. issue 3. 2004-01-09. PMID:12819990. |
the hippocampus, an important target of estrogen action, is severely affected in the alzheimer process. |
2004-01-09 |
2023-08-12 |
Not clear |
| Michito Adachi, Shinobu Kawakatsu, Takaaki Hosoya, Koichi Otani, Tsuguo Honma, Akiko Shibata, Yukio Suga. Morphology of the inner structure of the hippocampal formation in Alzheimer disease. AJNR. American journal of neuroradiology. vol 24. issue 8. 2004-01-08. PMID:13679273. |
we sought to demonstrate the anatomic details of the inner hippocampus and to elucidate its alterations in alzheimer disease (ad) in vivo. |
2004-01-08 |
2023-08-12 |
Not clear |
| Robert W Stackman, Felix Eckenstein, Balz Frei, Doris Kulhanek, Jessica Nowlin, Joseph F Quin. Prevention of age-related spatial memory deficits in a transgenic mouse model of Alzheimer's disease by chronic Ginkgo biloba treatment. Experimental neurology. vol 184. issue 1. 2004-01-05. PMID:14637120. |
alzheimer's disease (ad) is characterized by cognitive decline and deposition of beta-amyloid (abeta) plaques in cortex and hippocampus. |
2004-01-05 |
2023-08-12 |
mouse |
| Yeon-Kye Kim, Byung-Soo Koo, Dae-Jong Gong, Young-Choon Lee, Jeong-Heon Ko, Cheorl-Ho Ki. Comparative effect of Prunus persica L. BATSCH-water extract and tacrine (9-amino-1,2,3,4-tetrahydroacridine hydrochloride) on concentration of extracellular acetylcholine in the rat hippocampus. Journal of ethnopharmacology. vol 87. issue 2-3. 2003-12-29. PMID:12860300. |
in this study, the effects of oral administration of ppe on the extracellular acetylcholine concentration in the hippocampus of rats were evaluated, and compared to that of tacrine (9-amino-1,2,3,4-tetrahydroacridine hydrochloride), a well-known and centrally acting acetylcholinesterase (ache) inhibitor, which had been developed for the treatment of alzheimer's disease. |
2003-12-29 |
2023-08-12 |
rat |
| Cristina Benito, Estefanía Núñez, Rosa M Tolón, Erica J Carrier, Alberto Rábano, Cecilia J Hillard, Julián Romer. Cannabinoid CB2 receptors and fatty acid amide hydrolase are selectively overexpressed in neuritic plaque-associated glia in Alzheimer's disease brains. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 35. 2003-12-23. PMID:14657172. |
using specific polyclonal antibodies, we have performed immunohistochemical analysis in hippocampus and entorhinal cortex sections from brains of alzheimer's disease patients. |
2003-12-23 |
2023-08-12 |
human |
| J L W Yau, S Rasmuson, R Andrew, M Graham, J Noble, T Olsson, E Fuchs, R Lathe, J R Seck. Dehydroepiandrosterone 7-hydroxylase CYP7B: predominant expression in primate hippocampus and reduced expression in Alzheimer's disease. Neuroscience. vol 121. issue 2. 2003-12-19. PMID:14521990. |
dehydroepiandrosterone 7-hydroxylase cyp7b: predominant expression in primate hippocampus and reduced expression in alzheimer's disease. |
2003-12-19 |
2023-08-12 |
mouse |
| Lei Wang, Jeffrey S Swank, Irena E Glick, Mokhtar H Gado, Michael I Miller, John C Morris, John G Csernansk. Changes in hippocampal volume and shape across time distinguish dementia of the Alzheimer type from healthy aging. NeuroImage. vol 20. issue 2. 2003-12-19. PMID:14568443. |
changes in hippocampal volume and shape across time distinguish dementia of the alzheimer type from healthy aging. |
2003-12-19 |
2023-08-12 |
human |
| Lei Wang, Jeffrey S Swank, Irena E Glick, Mokhtar H Gado, Michael I Miller, John C Morris, John G Csernansk. Changes in hippocampal volume and shape across time distinguish dementia of the Alzheimer type from healthy aging. NeuroImage. vol 20. issue 2. 2003-12-19. PMID:14568443. |
rates of hippocampal volume loss have been shown to distinguish subjects with dementia of the alzheimer type (dat) from nondemented controls. |
2003-12-19 |
2023-08-12 |
human |
| D Champagne, D Pearson, D Dea, J Rochford, J Poirie. The cholesterol-lowering drug probucol increases apolipoprotein E production in the hippocampus of aged rats: implications for Alzheimer's disease. Neuroscience. vol 121. issue 1. 2003-12-05. PMID:12946703. |
the cholesterol-lowering drug probucol increases apolipoprotein e production in the hippocampus of aged rats: implications for alzheimer's disease. |
2003-12-05 |
2023-08-12 |
human |
| Henrietta Papp, I Török, A Matsumoto, T Enomoto, S Matsuyama, P Kás. Expression and distribution of carboxypeptidase B in the hippocampal subregions of normal and Alzheimer's disease brain. Acta biologica Hungarica. vol 54. issue 1. 2003-12-04. PMID:12705322. |
expression and distribution of carboxypeptidase b in the hippocampal subregions of normal and alzheimer's disease brain. |
2003-12-04 |
2023-08-12 |
human |
| Henrietta Papp, I Török, A Matsumoto, T Enomoto, S Matsuyama, P Kás. Expression and distribution of carboxypeptidase B in the hippocampal subregions of normal and Alzheimer's disease brain. Acta biologica Hungarica. vol 54. issue 1. 2003-12-04. PMID:12705322. |
using an immimohistochemical technique we report here on the neuronal expression and distribution of this enzyme in the segments (ca1a, ca1b and ca1c) of the ca1 subfield and in area ca4 of the hippocampus in normal and alzheimer's disease brain samples. |
2003-12-04 |
2023-08-12 |
human |
| R A Rissman, A J Mishizen-Eberz, T L Carter, B B Wolfe, A L De Blas, C P Miralles, M D Ikonomovic, D M Armstron. Biochemical analysis of GABA(A) receptor subunits alpha 1, alpha 5, beta 1, beta 2 in the hippocampus of patients with Alzheimer's disease neuropathology. Neuroscience. vol 120. issue 3. 2003-12-04. PMID:12895510. |
biochemical analysis of gaba(a) receptor subunits alpha 1, alpha 5, beta 1, beta 2 in the hippocampus of patients with alzheimer's disease neuropathology. |
2003-12-04 |
2023-08-12 |
human |
| Elly M Hol, Renske van Dijk, Lisya Gerez, Jacqueline A Sluijs, Barbara Hobo, Martijn T Tonk, Annett de Haan, Wouter Kamphorst, David F Fischer, Rob Benne, Fred W van Leeuwe. Frameshifted beta-amyloid precursor protein (APP+1) is a secretory protein, and the level of APP+1 in cerebrospinal fluid is linked to Alzheimer pathology. The Journal of biological chemistry. vol 278. issue 41. 2003-12-02. PMID:12900421. |
the resulting truncated and partly frameshifted app protein (app+1) accumulates in the dystrophic neurites and the neurofibrillary tangles in the cortex and hippocampus of alzheimer patients. |
2003-12-02 |
2023-08-12 |
human |