Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Joel H Kramer, Norbert Schuff, Bruce R Reed, Dan Mungas, An-Tao Du, Howard J Rosen, William J Jagust, Bruce L Miller, Michael W Weiner, Helena C Chu. Hippocampal volume and retention in Alzheimer's disease. Journal of the International Neuropsychological Society : JINS. vol 10. issue 4. 2004-10-08. PMID:15327742. |
hippocampal volume and retention in alzheimer's disease. |
2004-10-08 |
2023-08-12 |
human |
Haiyan Zeng, Qi Chen, Baolu Zha. Genistein ameliorates beta-amyloid peptide (25-35)-induced hippocampal neuronal apoptosis. Free radical biology & medicine. vol 36. issue 2. 2004-10-07. PMID:14744630. |
beta-amyloid protein (abeta), a major component of senile plaques of alzheimer's disease (ad) brain, causes elevation of the intracellular free ca2+ level and the production of robust free radicals, both of which contribute greatly to the ad-associated cascade including severe neuronal loss in the hippocampus. |
2004-10-07 |
2023-08-12 |
Not clear |
Anne-Mette Hejl, Birte Glenthøj, Torben Mackeprang, Ralf Hemmingsen, Gunhild Waldema. Prepulse inhibition in patients with Alzheimer's disease. Neurobiology of aging. vol 25. issue 8. 2004-10-04. PMID:15212829. |
studies in animals have indicated that hippocampus and entorhinal cortex, structures which are affected in mild alzheimer's disease (ad), are involved in the regulation of ppi. |
2004-10-04 |
2023-08-12 |
Not clear |
Kunlin Jin, Veronica Galvan, Lin Xie, Xiao Ou Mao, Olivia F Gorostiza, Dale E Bredesen, David A Greenber. Enhanced neurogenesis in Alzheimer's disease transgenic (PDGF-APPSw,Ind) mice. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 36. 2004-09-30. PMID:15340159. |
we reported recently that neurogenesis is enhanced in hippocampus of patients with alzheimer's disease (ad). |
2004-09-30 |
2023-08-12 |
mouse |
Esther S C Korf, Lon R White, Philip Scheltens, Lenore J Laune. Midlife blood pressure and the risk of hippocampal atrophy: the Honolulu Asia Aging Study. Hypertension (Dallas, Tex. : 1979). vol 44. issue 1. 2004-09-28. PMID:15159381. |
hippocampal atrophy (ha) is usually attributed to the neurofibrillary tangles and neuritic plaques of alzheimer disease. |
2004-09-28 |
2023-08-12 |
human |
Cristina Testa, Mikko P Laakso, Francesca Sabattoli, Roberta Rossi, Alberto Beltramello, Hilkka Soininen, Giovanni B Frison. A comparison between the accuracy of voxel-based morphometry and hippocampal volumetry in Alzheimer's disease. Journal of magnetic resonance imaging : JMRI. vol 19. issue 3. 2004-09-17. PMID:14994294. |
a comparison between the accuracy of voxel-based morphometry and hippocampal volumetry in alzheimer's disease. |
2004-09-17 |
2023-08-12 |
Not clear |
Cristina Testa, Mikko P Laakso, Francesca Sabattoli, Roberta Rossi, Alberto Beltramello, Hilkka Soininen, Giovanni B Frison. A comparison between the accuracy of voxel-based morphometry and hippocampal volumetry in Alzheimer's disease. Journal of magnetic resonance imaging : JMRI. vol 19. issue 3. 2004-09-17. PMID:14994294. |
to compare the accuracy of voxel-based morphometry (vbm) and region of interest (roi)-based hippocampal volumetry to detect medial temporal lobe atrophy in alzheimer's disease (ad). |
2004-09-17 |
2023-08-12 |
Not clear |
Tze-Fun Lee, Chieh-Fu Chen, Lawrence C H Wan. Effect of ginkgolides on beta-amyloid-suppressed acetylocholine release from rat hippocampal slices. Phytotherapy research : PTR. vol 18. issue 7. 2004-09-16. PMID:15305316. |
as ginkgo has been shown to improve age-related memory de fi cits and beta-amyloid-related peptides have been suggested to play a signi fi cant role in memory degeneration in alzheimer's disease, the present study was carried out to examine the effect of two major ginkgolides, a and b, on beta-amyloid peptide-modulated acetylcholine (ach) release from hippocampal brain slices. |
2004-09-16 |
2023-08-12 |
rat |
J L Rekart, B Quinn, M-M Mesulam, A Routtenber. Subfield-specific increase in brain growth protein in postmortem hippocampus of Alzheimer's patients. Neuroscience. vol 126. issue 3. 2004-09-14. PMID:15183507. |
subfield-specific increase in brain growth protein in postmortem hippocampus of alzheimer's patients. |
2004-09-14 |
2023-08-12 |
human |
Min-Hua Luo, Sze-Wah Tse, John Memmott, Athena Andreadi. Novel isoforms of tau that lack the microtubule-binding domain. Journal of neurochemistry. vol 90. issue 2. 2004-09-03. PMID:15228591. |
in both normal and alzheimer's hippocampus, the novel isoform is found in dentate gyrus granular cells and ca1/ca3 pyramidal cells. |
2004-09-03 |
2023-08-12 |
human |
Cláudia Pereira, Elisabete Ferreiro, Sandra Morais Cardoso, Catarina Resende de Oliveir. Cell degeneration induced by amyloid-beta peptides: implications for Alzheimer's disease. Journal of molecular neuroscience : MN. vol 23. issue 1-2. 2004-09-01. PMID:15126695. |
extracellular accumulation of amyloid-beta (abeta) peptide and death of neurons in brain regions involved in learning and memory, particularly the cortex and the hippocampus, are central features of alzheimer's disease (ad). |
2004-09-01 |
2023-08-12 |
Not clear |
Maria Dolores Ledesma, José Abad-Rodriguez, Cristian Galvan, Elisa Biondi, Pilar Navarro, Andre Delacourte, Colin Dingwall, Carlos G Dott. Raft disorganization leads to reduced plasmin activity in Alzheimer's disease brains. EMBO reports. vol 4. issue 12. 2004-08-31. PMID:14618158. |
the serine protease plasmin can efficiently degrade amyloid peptide in vitro, and is found at low levels in the hippocampus of patients with alzheimer's disease (ad). |
2004-08-31 |
2023-08-12 |
Not clear |
Jillian J Kril, John Hodges, Glenda Hallida. Relationship between hippocampal volume and CA1 neuron loss in brains of humans with and without Alzheimer's disease. Neuroscience letters. vol 361. issue 1-3. 2004-08-30. PMID:15135880. |
relationship between hippocampal volume and ca1 neuron loss in brains of humans with and without alzheimer's disease. |
2004-08-30 |
2023-08-12 |
human |
Jillian J Kril, John Hodges, Glenda Hallida. Relationship between hippocampal volume and CA1 neuron loss in brains of humans with and without Alzheimer's disease. Neuroscience letters. vol 361. issue 1-3. 2004-08-30. PMID:15135880. |
hippocampal volumetry has been proposed to aid in the early diagnosis of alzheimer's disease (ad) and to monitor progression of the disease. |
2004-08-30 |
2023-08-12 |
human |
Virginia Zbarsky, Justyn Thomas, Susan Greenfiel. Bioactivity of a peptide derived from acetylcholinesterase: involvement of an ivermectin-sensitive site on the alpha 7 nicotinic receptor. Neurobiology of disease. vol 16. issue 1. 2004-08-18. PMID:15207285. |
this peptide is bioactive in a variety of systems including acute (brain slices) and chronic (organotypic culture) preparations of hippocampus, a pivotal area in alzheimer's disease (ad); invariably, the action of the peptide is mediated specifically via an as yet unknown receptor. |
2004-08-18 |
2023-08-12 |
Not clear |
Carlos Velez-Pardo, Jon I Arellano, Patricia Cardona-Gomez, Marlene Jimenez Del Rio, Francisco Lopera, Javier De Felip. CA1 hippocampal neuronal loss in familial Alzheimer's disease presenilin-1 E280A mutation is related to epilepsy. Epilepsia. vol 45. issue 7. 2004-08-11. PMID:15230697. |
ca1 hippocampal neuronal loss in familial alzheimer's disease presenilin-1 e280a mutation is related to epilepsy. |
2004-08-11 |
2023-08-12 |
Not clear |
Paul H Wen, Patrick R Hof, Xiaoping Chen, Karen Gluck, Gregory Austin, Steven G Younkin, Linda H Younkin, Rita DeGasperi, Miguel A Gama Sosa, Nikolaos K Robakis, Vahram Haroutunian, Gregory A Elde. The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice. Experimental neurology. vol 188. issue 2. 2004-08-10. PMID:15246822. |
the presenilin-1 familial alzheimer disease mutant p117l impairs neurogenesis in the hippocampus of adult mice. |
2004-08-10 |
2023-08-12 |
mouse |
Huali Wang, Huishu Yuan, Liang Shu, Jingxia Xie, Dai Zhan. Prolongation of T(2) relaxation times of hippocampus and amygdala in Alzheimer's disease. Neuroscience letters. vol 363. issue 2. 2004-08-04. PMID:15172104. |
prolongation of t(2) relaxation times of hippocampus and amygdala in alzheimer's disease. |
2004-08-04 |
2023-08-12 |
human |
Huali Wang, Huishu Yuan, Liang Shu, Jingxia Xie, Dai Zhan. Prolongation of T(2) relaxation times of hippocampus and amygdala in Alzheimer's disease. Neuroscience letters. vol 363. issue 2. 2004-08-04. PMID:15172104. |
there exists controversy on the mr t(2) relaxometry of hippocampus in alzheimer's disease (ad). |
2004-08-04 |
2023-08-12 |
human |
Walter J Luki. Gene expression profiling in fetal, aged, and Alzheimer hippocampus: a continuum of stress-related signaling. Neurochemical research. vol 29. issue 6. 2004-07-26. PMID:15176485. |
gene expression profiling in fetal, aged, and alzheimer hippocampus: a continuum of stress-related signaling. |
2004-07-26 |
2023-08-12 |
Not clear |