| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wen-Feng Yu, Zhi-Zhong Guan, Nenad Bogdanovic, Agneta Nordber. High selective expression of alpha7 nicotinic receptors on astrocytes in the brains of patients with sporadic Alzheimer's disease and patients carrying Swedish APP 670/671 mutation: a possible association with neuritic plaques. Experimental neurology. vol 192. issue 1. 2005-04-14. PMID:15698636. |
in the present study, we have investigated the expression of nicotinic acetylcholine receptors (nachrs) on astrocytes and neurons in the hippocampus and temporal cortex of subjects carrying the swedish amyloid precursor protein (app) 670/671 mutation (appswe), patients with sporadic alzheimer's disease (ad), and age-matched control subjects. |
2005-04-14 |
2023-08-12 |
human |
| Su Jeon Shin, Sung-Eun Lee, Jung Hyun Boo, Mihyang Kim, Young-Dae Yoon, Su-il Kim, Inhee Mook-Jun. Profiling proteins related to amyloid deposited brain of Tg2576 mice. Proteomics. vol 4. issue 11. 2005-04-13. PMID:15378736. |
alzheimer's disease (ad) is an age-related neurodegenerative disorder that is characterized by the extracellular deposition of beta-amyloid and intracellular hyperphosphorylation of tau in the cortex and hippocampus of the brain. |
2005-04-13 |
2023-08-12 |
mouse |
| Nibaldo C Inestrosa, Juan Paulo Sagal, Marcela Colombre. Acetylcholinesterase interaction with Alzheimer amyloid beta. Sub-cellular biochemistry. vol 38. 2005-04-12. PMID:15709485. |
the neurotoxicity induced by ache-abeta complexes indicated that they trigger more neurodegeneration than those of the abeta peptide alone, both in vitro (hippocampal neurons) and in vivo (rats injected in the dorsal hippocampus as a model of alzheimer). |
2005-04-12 |
2023-08-12 |
rat |
| Janka Koschack, Eva Irl. Small hippocampal size in cognitively normal subjects with coronary artery disease. Neurobiology of aging. vol 26. issue 6. 2005-04-12. PMID:15718045. |
hippocampal size reduction detected by three-dimensional structural magnetic resonance imaging (3d-mri) represents an important hallmark of alzheimer's disease (ad). |
2005-04-12 |
2023-08-12 |
human |
| Paul Mohapel, Giampiero Leanza, Merab Kokaia, Olle Lindval. Forebrain acetylcholine regulates adult hippocampal neurogenesis and learning. Neurobiology of aging. vol 26. issue 6. 2005-04-12. PMID:15718053. |
the hippocampus receives abundant cholinergic innervation and acetylcholine (ach) plays an important role in learning and alzheimer's disease (ad) pathophysiology. |
2005-04-12 |
2023-08-12 |
Not clear |
| François Laplante, Jacqueline N Crawley, Rémi Quirio. Selective reduction in ventral hippocampal acetylcholine release in awake galanin-treated rats and galanin-overexpressing transgenic mice. Regulatory peptides. vol 122. issue 2. 2005-04-08. PMID:15380926. |
these results are of interest in the context of galanin receptor subtypes in the dorsal and ventral hippocampus, and the differential alterations of hippocampal subregions in neurological diseases such as alzheimer's dementia. |
2005-04-08 |
2023-08-12 |
mouse |
| John G Csernansky, Julia Hamstra, Lei Wang, Daniel McKeel, Joseph L Price, Mokhtar Gado, John C Morri. Correlations between antemortem hippocampal volume and postmortem neuropathology in AD subjects. Alzheimer disease and associated disorders. vol 18. issue 4. 2005-04-05. PMID:15592129. |
antemortem measures of hippocampal volume have been used to distinguish subjects with and without probable alzheimer disease (ad). |
2005-04-05 |
2023-08-12 |
human |
| Frank Ezekiel, Linda Chao, John Kornak, An-Tao Du, Valerie Cardenas, Diana Truran, William Jagust, Helena Chui, Bruce Miller, Kristine Yaffe, Norbert Schuff, Michael Weine. Comparisons between global and focal brain atrophy rates in normal aging and Alzheimer disease: Boundary Shift Integral versus tracing of the entorhinal cortex and hippocampus. Alzheimer disease and associated disorders. vol 18. issue 4. 2005-04-05. PMID:15592130. |
comparisons between global and focal brain atrophy rates in normal aging and alzheimer disease: boundary shift integral versus tracing of the entorhinal cortex and hippocampus. |
2005-04-05 |
2023-08-12 |
Not clear |
| Frank Ezekiel, Linda Chao, John Kornak, An-Tao Du, Valerie Cardenas, Diana Truran, William Jagust, Helena Chui, Bruce Miller, Kristine Yaffe, Norbert Schuff, Michael Weine. Comparisons between global and focal brain atrophy rates in normal aging and Alzheimer disease: Boundary Shift Integral versus tracing of the entorhinal cortex and hippocampus. Alzheimer disease and associated disorders. vol 18. issue 4. 2005-04-05. PMID:15592130. |
the objectives of this study were to (1) compare atrophy rates associated with normal aging and alzheimer disease (ad) using the semi-automated boundary shift integral (bsi) method and manual tracing of the entorhinal cortex (erc) and hippocampus and (2) calculate power of bsi vs. erc and hippocampal volume changes for clinical trials in ad. |
2005-04-05 |
2023-08-12 |
Not clear |
| Paul F Good, Daisy Alapat, Amy Hsu, Caryn Chu, Daniel Perl, Xiaping Wen, David E Burstein, D Stave Koht. A role for semaphorin 3A signaling in the degeneration of hippocampal neurons during Alzheimer's disease. Journal of neurochemistry. vol 91. issue 3. 2005-03-24. PMID:15485501. |
a role for semaphorin 3a signaling in the degeneration of hippocampal neurons during alzheimer's disease. |
2005-03-24 |
2023-08-12 |
Not clear |
| Yue-Ju Wang, Gui-Hai Chen, Xiang-You Hu, Ya-Ping Lu, Jiang-Ning Zhou, Rong-Yu Li. The expression of calcium/calmodulin-dependent protein kinase II-alpha in the hippocampus of patients with Alzheimer's disease and its links with AD-related pathology. Brain research. vol 1031. issue 1. 2005-03-18. PMID:15621017. |
the expression of calcium/calmodulin-dependent protein kinase ii-alpha in the hippocampus of patients with alzheimer's disease and its links with ad-related pathology. |
2005-03-18 |
2023-08-12 |
Not clear |
| Chih-Wei Wu, Pao-Chi Liao, Lung Yu, Shan-Tair Wang, Shur-Tzu Chen, Ching-Ming Wu, Yu-Min Ku. Hemoglobin promotes Abeta oligomer formation and localizes in neurons and amyloid deposits. Neurobiology of disease. vol 17. issue 3. 2005-03-07. PMID:15571973. |
hemoglobin was distributed in alzheimer's disease (ad) patients in a brain region-dependent manner, with the highest levels in the hippocampus and parietal gray (pg) matter, followed by parietal white matter (pw), and the lowest in cerebellum (cb). |
2005-03-07 |
2023-08-12 |
human |
| R R Davies, Kim S Graham, John H Xuereb, Guy B Williams, John R Hodge. The human perirhinal cortex and semantic memory. The European journal of neuroscience. vol 20. issue 9. 2005-03-04. PMID:15525284. |
bilateral reduction in hippocampal volume compared with controls was seen in alzheimer's disease. |
2005-03-04 |
2023-08-12 |
human |
| D M Blass, K J Hatanpaa, J Brandt, V Rao, M Steinberg, J C Troncoso, P V Rabin. Dementia in hippocampal sclerosis resembles frontotemporal dementia more than Alzheimer disease. Neurology. vol 63. issue 3. 2005-03-01. PMID:15304580. |
dementia in hippocampal sclerosis resembles frontotemporal dementia more than alzheimer disease. |
2005-03-01 |
2023-08-12 |
Not clear |
| P Murali Doraiswamy, David C Steffens, Douglas R McQuoi. Statin use and hippocampal volumes in elderly subjects at risk for Alzheimer's disease: a pilot observational study. American journal of Alzheimer's disease and other dementias. vol 19. issue 5. 2005-02-25. PMID:15553983. |
statin use and hippocampal volumes in elderly subjects at risk for alzheimer's disease: a pilot observational study. |
2005-02-25 |
2023-08-12 |
human |
| Satyabrata Kar, Stephen P M Slowikowski, David Westaway, Howard T J Moun. Interactions between beta-amyloid and central cholinergic neurons: implications for Alzheimer's disease. Journal of psychiatry & neuroscience : JPN. vol 29. issue 6. 2005-02-23. PMID:15644984. |
the brain of an individual with alzheimer's disease exhibits extracellular plaques of aggregated beta-amyloid protein (abeta), intracellular neurofibrillary tangles that contain hyperphosphorylated tau protein and a profound loss of basal forebrain cholinergic neurons that innervate the hippocampus and the neocortex. |
2005-02-23 |
2023-08-12 |
Not clear |
| Yoshio Bando, Reiko Onuki, Taiichi Katayama, Takayuki Manabe, Takashi Kudo, Kazunari Taira, Masaya Tohyam. Double-strand RNA dependent protein kinase (PKR) is involved in the extrastriatal degeneration in Parkinson's disease and Huntington's disease. Neurochemistry international. vol 46. issue 1. 2005-02-22. PMID:15567511. |
we previously reported that activation of pkr is associated with hippocampal neuronal loss in alzheimer's disease (ad). |
2005-02-22 |
2023-08-12 |
Not clear |
| Freya G G Vercauteren, Stefan Clerens, Line Roy, Nathalie Hamel, Lut Arckens, Frans Vandesande, Leena Alhonen, Juhani Janne, Moshe Szyf, A Claudio Cuell. Early dysregulation of hippocampal proteins in transgenic rats with Alzheimer's disease-linked mutations in amyloid precursor protein and presenilin 1. Brain research. Molecular brain research. vol 132. issue 2. 2005-01-31. PMID:15582162. |
early dysregulation of hippocampal proteins in transgenic rats with alzheimer's disease-linked mutations in amyloid precursor protein and presenilin 1. |
2005-01-31 |
2023-08-12 |
rat |
| Freya G G Vercauteren, Stefan Clerens, Line Roy, Nathalie Hamel, Lut Arckens, Frans Vandesande, Leena Alhonen, Juhani Janne, Moshe Szyf, A Claudio Cuell. Early dysregulation of hippocampal proteins in transgenic rats with Alzheimer's disease-linked mutations in amyloid precursor protein and presenilin 1. Brain research. Molecular brain research. vol 132. issue 2. 2005-01-31. PMID:15582162. |
the response of the hippocampal proteome to expression of mutant proteins present in familial forms of alzheimer's disease (ad) was studied using transgenic rats. |
2005-01-31 |
2023-08-12 |
rat |
| Raj N Kalaria, Rose Anne Kenny, Clive G Ballard, Robert Perry, Paul Ince, Tuomo Polvikosk. Towards defining the neuropathological substrates of vascular dementia. Journal of the neurological sciences. vol 226. issue 1-2. 2005-01-19. PMID:15537525. |
other pathologies including hippocampal injury and alzheimer type of lesions may also modify the course of dementia. |
2005-01-19 |
2023-08-12 |
Not clear |