| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takashi Saito, Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki, Jiro Takano, Shu-Ming Huang, Takahiro Suemoto, Makoto Higuchi, Takaomi C Said. Somatostatin regulates brain amyloid beta peptide Abeta42 through modulation of proteolytic degradation. Nature medicine. vol 11. issue 4. 2005-06-30. PMID:15778722. |
a genetic deficiency of somatostatin altered hippocampal neprilysin activity and localization, and increased the quantity of a hydrophobic 42-mer form of abeta, abeta(42), in a manner similar to presenilin gene mutations that cause familial alzheimer disease. |
2005-06-30 |
2023-08-12 |
Not clear |
| Adam Fleisher, Michael Grundman, Clifford R Jack, Ronald C Petersen, Curtis Taylor, Hyun T Kim, Denise H B Schiller, Victor Bagwell, Drahomira Sencakova, Myron F Weiner, Charles DeCarli, Steven T DeKosky, Christopher H van Dyck, Leon J Tha. Sex, apolipoprotein E epsilon 4 status, and hippocampal volume in mild cognitive impairment. Archives of neurology. vol 62. issue 6. 2005-06-30. PMID:15956166. |
the presence of the apolipoprotein e epsilon4 (apoe*e4) allele has been associated with greater hippocampal atrophy in women than in men with alzheimer disease. |
2005-06-30 |
2023-08-12 |
human |
| Tom den Heijer, Albert Hofman, Peter J Koudstaal, Monique M B Bretele. Serum lipids and hippocampal volume: the link to Alzheimer's disease? Annals of neurology. vol 57. issue 5. 2005-06-24. PMID:15852390. |
serum lipids and hippocampal volume: the link to alzheimer's disease? |
2005-06-24 |
2023-08-12 |
Not clear |
| Changqing Xu, Kimmo A Michelsen, Min Wu, Elena Morozova, Pertti Panula, Meenakshi Alrej. Histamine innervation and activation of septohippocampal GABAergic neurones: involvement of local ACh release. The Journal of physiology. vol 561. issue Pt 3. 2005-06-21. PMID:15486020. |
these findings have significance for alzheimer's disease and other neurodegenerative disorders involving a loss of septohippocampal cholinergic neurones as such a loss would also obtund histamine effects on septohippocampal cholinergic and gabaergic functions and further compromise hippocampal arousal and associated cognitive functions. |
2005-06-21 |
2023-08-12 |
Not clear |
| Harald Hampel, Katharina Bürger, Jens C Pruessner, Raymond Zinkowski, John DeBernardis, Daniel Kerkman, Gerda Leinsinger, Alan C Evans, Peter Davies, Hans-Jürgen Möller, Stefan J Teipe. Correlation of cerebrospinal fluid levels of tau protein phosphorylated at threonine 231 with rates of hippocampal atrophy in Alzheimer disease. Archives of neurology. vol 62. issue 5. 2005-06-17. PMID:15883264. |
correlation of cerebrospinal fluid levels of tau protein phosphorylated at threonine 231 with rates of hippocampal atrophy in alzheimer disease. |
2005-06-17 |
2023-08-12 |
Not clear |
| Tatyana Tchaikovskaya, Vadim Fraifeld, Tinatin Urphanishvili, John H Andorfer, Peter Davies, Irving Listowsk. Glutathione S-transferase hGSTM3 and ageing-associated neurodegeneration: relationship to Alzheimer's disease. Mechanisms of ageing and development. vol 126. issue 2. 2005-06-13. PMID:15621212. |
immunocytochemistry performed with hgstm3-specific antisera, showed prominent staining of neuritic plaques, neurofibrillary tangles and microglia in sections of hippocampus obtained from patients with alzheimer's disease. |
2005-06-13 |
2023-08-12 |
human |
| Jae-Kwang Jin, Jin-Kyu Choi, Wilma Wasco, Joseph D Buxbaum, Piotr B Kozlowski, Richard I Carp, Yong-Sun Kim, Eun-Kyoung Cho. Expression of calsenilin in neurons and astrocytes in the Alzheimer's disease brain. Neuroreport. vol 16. issue 5. 2005-06-06. PMID:15770150. |
both messenger rna and protein expression of calsenilin were observed in neurons of the cerebral cortex and hippocampus of control brains, and more intense staining was in alzheimer's disease brains. |
2005-06-06 |
2023-08-12 |
Not clear |
| Josefine Andin, Albert Enz, Conrad Gentsch, Jan Marcusso. Rivastigmine as a modulator of the neuronal glutamate transporter rEAAC1 mRNA expression. Dementia and geriatric cognitive disorders. vol 19. issue 1. 2005-05-31. PMID:15383741. |
alzheimer's disease is a neurodegenerative disorder that affects the cholinergic, glutamatergic and monoaminergic systems in the neocortex and hippocampus. |
2005-05-31 |
2023-08-12 |
rat |
| Akihito Ishigami, Takako Ohsawa, Masaharu Hiratsuka, Hiromi Taguchi, Saori Kobayashi, Yuko Saito, Shigeo Murayama, Hiroaki Asaga, Tosifusa Toda, Narimichi Kimura, Naoki Maruyam. Abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with Alzheimer's disease. Journal of neuroscience research. vol 80. issue 1. 2005-05-26. PMID:15704193. |
abnormal accumulation of citrullinated proteins catalyzed by peptidylarginine deiminase in hippocampal extracts from patients with alzheimer's disease. |
2005-05-26 |
2023-08-12 |
human |
| Pamela J Yao, Ittai Bushlin, Katsutoshi Furukaw. Preserved synaptic vesicle recycling in hippocampal neurons in a mouse Alzheimer's disease model. Biochemical and biophysical research communications. vol 330. issue 1. 2005-05-26. PMID:15781228. |
preserved synaptic vesicle recycling in hippocampal neurons in a mouse alzheimer's disease model. |
2005-05-26 |
2023-08-12 |
mouse |
| Eloy Rivas, Joaquin Sanchez-Herrero, Miguel Alonso, Maria J Alvarez, Susana Teijeira, Claudio Ballestín, Antoni Tardio, Carmen Navarr. Miliary brain metastases presenting as rapidly progressive dementia. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 25. issue 2. 2005-05-26. PMID:15875909. |
histopathological changes of alzheimer's disease were also observed in the cerebral cortex and hippocampus. |
2005-05-26 |
2023-08-12 |
Not clear |
| Armin von Gunten, Enikö Kövari, Claire-Bénédicte Rivara, Constantin Bouras, Patrick R Hof, Panteleimon Giannakopoulo. Stereologic analysis of hippocampal Alzheimer's disease pathology in the oldest-old: evidence for sparing of the entorhinal cortex and CA1 field. Experimental neurology. vol 193. issue 1. 2005-05-24. PMID:15817278. |
stereologic analysis of hippocampal alzheimer's disease pathology in the oldest-old: evidence for sparing of the entorhinal cortex and ca1 field. |
2005-05-24 |
2023-08-12 |
Not clear |
| Armin von Gunten, Enikö Kövari, Claire-Bénédicte Rivara, Constantin Bouras, Patrick R Hof, Panteleimon Giannakopoulo. Stereologic analysis of hippocampal Alzheimer's disease pathology in the oldest-old: evidence for sparing of the entorhinal cortex and CA1 field. Experimental neurology. vol 193. issue 1. 2005-05-24. PMID:15817278. |
several neuropathologic analyses postulate that alzheimer disease (ad) in the oldest-old is associated with substantial neurofibrillary tangle (nft) formation in the ca fields of the hippocampus and neuronal loss confined to the entorhinal cortex. |
2005-05-24 |
2023-08-12 |
Not clear |
| Pedro J Modrego, Nicolás Fayed, Miguel A Pin. Conversion from mild cognitive impairment to probable Alzheimer's disease predicted by brain magnetic resonance spectroscopy. The American journal of psychiatry. vol 162. issue 4. 2005-05-17. PMID:15800137. |
the authors' objective was to determine whether findings from magnetic resonance spectroscopy (mrs) of the hippocampus and other cortical areas would predict conversion from amnestic mild cognitive impairment to probable alzheimer's disease. |
2005-05-17 |
2023-08-12 |
Not clear |
| Mamoru Hashimoto, Hiroaki Kazui, Keiji Matsumoto, Yoko Nakano, Minoru Yasuda, Etsuro Mor. Does donepezil treatment slow the progression of hippocampal atrophy in patients with Alzheimer's disease? The American journal of psychiatry. vol 162. issue 4. 2005-05-17. PMID:15800138. |
does donepezil treatment slow the progression of hippocampal atrophy in patients with alzheimer's disease? |
2005-05-17 |
2023-08-12 |
Not clear |
| Mamoru Hashimoto, Hiroaki Kazui, Keiji Matsumoto, Yoko Nakano, Minoru Yasuda, Etsuro Mor. Does donepezil treatment slow the progression of hippocampal atrophy in patients with Alzheimer's disease? The American journal of psychiatry. vol 162. issue 4. 2005-05-17. PMID:15800138. |
the purpose of the present study was to determine whether donepezil has a neuroprotective effect in alzheimer's disease by using the rate of hippocampal atrophy as a surrogate marker of disease progression. |
2005-05-17 |
2023-08-12 |
Not clear |
| Egemen Savaskan, Mohammed A Ayoub, Rivka Ravid, Debora Angeloni, Franco Fraschini, Fides Meier, Anne Eckert, Franz Müller-Spahn, Ralf Jocker. Reduced hippocampal MT2 melatonin receptor expression in Alzheimer's disease. Journal of pineal research. vol 38. issue 1. 2005-05-12. PMID:15617532. |
reduced hippocampal mt2 melatonin receptor expression in alzheimer's disease. |
2005-05-12 |
2023-08-12 |
human |
| Egemen Savaskan, Mohammed A Ayoub, Rivka Ravid, Debora Angeloni, Franco Fraschini, Fides Meier, Anne Eckert, Franz Müller-Spahn, Ralf Jocker. Reduced hippocampal MT2 melatonin receptor expression in Alzheimer's disease. Journal of pineal research. vol 38. issue 1. 2005-05-12. PMID:15617532. |
the aim of the present study was to identify the distribution of the second melatonin receptor (mt2) in the human hippocampus of elderly controls and alzheimer's disease (ad) patients. |
2005-05-12 |
2023-08-12 |
human |
| Lorise C Gahring, Karina Persiyanov, Emily L Days, Scott W Roger. Age-related loss of neuronal nicotinic receptor expression in the aging mouse hippocampus corresponds with cyclooxygenase-2 and PPAR gamma expression and is altered by long-term NS398 administration. Journal of neurobiology. vol 62. issue 4. 2005-04-28. PMID:15551346. |
age-related changes in the mammalian dorsal hippocampus are associated with diminished expression of neuronal nicotinic acetylcholine receptors (nachr), which is particularly severe in pathologies such as those associated with dementias, including alzheimer's disease. |
2005-04-28 |
2023-08-12 |
mouse |
| Helen E Scharfman, Neil J Maclusk. Similarities between actions of estrogen and BDNF in the hippocampus: coincidence or clue? Trends in neurosciences. vol 28. issue 2. 2005-04-25. PMID:15667930. |
furthermore, disruption of the relationship between estrogen and bdnf could contribute to neurological and psychiatric disorders that have been associated with the hippocampus, such as alzheimer's disease, depression and epilepsy. |
2005-04-25 |
2023-08-12 |
Not clear |