| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A G Pearson, M A Curtis, H J Waldvogel, R L M Faull, M Draguno. Activating transcription factor 2 expression in the adult human brain: association with both neurodegeneration and neurogenesis. Neuroscience. vol 133. issue 2. 2005-08-30. PMID:15878807. |
in contrast to normal cases, atf2 expression is down-regulated in the hippocampus, substantia nigra pars compacta and caudate nucleus of the neurological diseases alzheimer's, parkinson's and huntington's, respectively. |
2005-08-30 |
2023-08-12 |
mouse |
| Nibal Ackl, Marcus Ising, Yvonne A Schreiber, Monika Atiya, Annette Sonntag, Dorothee P Aue. Hippocampal metabolic abnormalities in mild cognitive impairment and Alzheimer's disease. Neuroscience letters. vol 384. issue 1-2. 2005-08-22. PMID:15905028. |
hippocampal metabolic abnormalities in mild cognitive impairment and alzheimer's disease. |
2005-08-22 |
2023-08-12 |
human |
| Wang Hao, Wu Xing-Jun, Cui Yong-Yao, Zhu Liang, Lu Yang, Chen Hong-Zhua. Up-regulation of M1 muscarinic receptors expressed in CHOm1 cells by panaxynol via cAMP pathway. Neuroscience letters. vol 383. issue 1-2. 2005-08-22. PMID:15936523. |
loss of cholinergic neurons along with muscarinic acetylcholine receptors (machrs) in cerebral cortex and hippocampus is closely associated with alzheimer's disease (ad). |
2005-08-22 |
2023-08-12 |
human |
| Egemen Savaskan, Rivka Ravid, Fides Meier, Franz Müller-Spahn, Ralf Jocker. Immunohistochemical Localization of Fas-associated phosphatase-1 (FAP-1) in Alzheimer disease hippocampus. Applied immunohistochemistry & molecular morphology : AIMM. vol 13. issue 2. 2005-08-18. PMID:15894934. |
immunohistochemical localization of fas-associated phosphatase-1 (fap-1) in alzheimer disease hippocampus. |
2005-08-18 |
2023-08-12 |
human |
| Egemen Savaskan, Rivka Ravid, Fides Meier, Franz Müller-Spahn, Ralf Jocker. Immunohistochemical Localization of Fas-associated phosphatase-1 (FAP-1) in Alzheimer disease hippocampus. Applied immunohistochemistry & molecular morphology : AIMM. vol 13. issue 2. 2005-08-18. PMID:15894934. |
because apoptosis is a common mechanism leading to neuronal death in neurodegenerative disorders, the authors investigated the immunohistochemical distribution of fap-1 in the hippocampus of elderly control subjects and alzheimer disease (ad) patients. |
2005-08-18 |
2023-08-12 |
human |
| Kristel Sleegers, Tom den Heijer, Ewoud J van Dijk, Albert Hofman, Aida M Bertoli-Avella, Peter J Koudstaal, Monique M B Breteler, Cornelia M van Duij. ACE gene is associated with Alzheimer's disease and atrophy of hippocampus and amygdala. Neurobiology of aging. vol 26. issue 8. 2005-08-18. PMID:15917098. |
ace gene is associated with alzheimer's disease and atrophy of hippocampus and amygdala. |
2005-08-18 |
2023-08-12 |
human |
| Michael Fountoulakis, George T Tsangaris, Antony Maris, Gert Lube. The rat brain hippocampus proteome. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. vol 819. issue 1. 2005-08-01. PMID:15797529. |
in humans, the ca1 area of hippocampus is one of the first brain areas to display pathology in alzheimer's disease. |
2005-08-01 |
2023-08-12 |
rat |
| J G Csernansky, L Wang, J Swank, J P Miller, M Gado, D McKeel, M I Miller, J C Morri. Preclinical detection of Alzheimer's disease: hippocampal shape and volume predict dementia onset in the elderly. NeuroImage. vol 25. issue 3. 2005-07-29. PMID:15808979. |
preclinical detection of alzheimer's disease: hippocampal shape and volume predict dementia onset in the elderly. |
2005-07-29 |
2023-08-12 |
human |
| J G Csernansky, L Wang, J Swank, J P Miller, M Gado, D McKeel, M I Miller, J C Morri. Preclinical detection of Alzheimer's disease: hippocampal shape and volume predict dementia onset in the elderly. NeuroImage. vol 25. issue 3. 2005-07-29. PMID:15808979. |
structural deformity of the hippocampus is characteristic of individuals with very mild and mild forms of dementia of the alzheimer type (dat). |
2005-07-29 |
2023-08-12 |
human |
| Haruo Hanyu, Soichiro Shimizu, Yuriko Tanaka, Hidekazu Kanetaka, Toshihiko Iwamoto, Kimihiko Ab. Differences in magnetization transfer ratios of the hippocampus between dementia with Lewy bodies and Alzheimer's disease. Neuroscience letters. vol 380. issue 1-2. 2005-07-28. PMID:15854771. |
differences in magnetization transfer ratios of the hippocampus between dementia with lewy bodies and alzheimer's disease. |
2005-07-28 |
2023-08-12 |
human |
| Chris Zarow, Harry V Vinters, William G Ellis, Michael W Weiner, Dan Mungas, Lon White, Helena C Chu. Correlates of hippocampal neuron number in Alzheimer's disease and ischemic vascular dementia. Annals of neurology. vol 57. issue 6. 2005-07-26. PMID:15929035. |
correlates of hippocampal neuron number in alzheimer's disease and ischemic vascular dementia. |
2005-07-26 |
2023-08-12 |
Not clear |
| Chris Zarow, Harry V Vinters, William G Ellis, Michael W Weiner, Dan Mungas, Lon White, Helena C Chu. Correlates of hippocampal neuron number in Alzheimer's disease and ischemic vascular dementia. Annals of neurology. vol 57. issue 6. 2005-07-26. PMID:15929035. |
the cornu ammonis 1 region of the hippocampus (ca1) sector of hippocampus is vulnerable to both alzheimer's disease (ad)-type neurofibrillary degeneration and anoxia-ischemia. |
2005-07-26 |
2023-08-12 |
Not clear |
| E A Maguir. Remembering the past: neuroimaging studies of human memory. Bulletin et memoires de l'Academie royale de medecine de Belgique. vol 159. issue Pt 2. 2005-07-25. PMID:15615087. |
impairment of these abilities are among the first symptoms to be reported in patients with pathologies such as alzheimer's disease and anoxia that are linked to the hippocampus and other limbic structures. |
2005-07-25 |
2023-08-12 |
Not clear |
| Zhen Yan, Jian Fen. Alzheimer's disease: interactions between cholinergic functions and beta-amyloid. Current Alzheimer research. vol 1. issue 4. 2005-07-21. PMID:15975053. |
alzheimer's disease (ad) is characterized by two major features: (1) degeneration of basal forebrain cholinergic neurons and ensuing deficient cholinergic functions in cortex and hippocampus; (2) extracellular protein aggregates containing beta-amyloid peptides (abeta) in these cholinergic target areas. |
2005-07-21 |
2023-08-12 |
Not clear |
| Wang Xiao-Chuan, Hu Zheng-Hui, Fang Zheng-Yu, Feng Yue, Yang Yun-Huang, Wang Qun, Tang Xiao-Wei, Wu Yi-Gen, Wang Jian-Zh. Correlation of Alzheimer-like tau hyperphosphorylation and fMRI bold intensity. Current Alzheimer research. vol 1. issue 2. 2005-07-21. PMID:15975079. |
to explore the correlation between cerebral functional alterations revealed by functional magnetic resonance imaging (fmri) and alzheimer disease- (ad)-like tau hyperphosphorylation, we injected bilaterally 2 microl each of 20 mm isoproterenol (ip), a pka activator, or of saline as a vehicle control into the hippocampus of rats. |
2005-07-21 |
2023-08-12 |
rat |
| E Geuze, E Vermetten, J D Bremne. MR-based in vivo hippocampal volumetrics: 2. Findings in neuropsychiatric disorders. Molecular psychiatry. vol 10. issue 2. 2005-07-15. PMID:15356639. |
smaller hippocampal volumes have been reported in epilepsy, alzheimer's disease, dementia, mild cognitive impairment, the aged, traumatic brain injury, cardiac arrest, parkinson's disease, huntington's disease, cushing's disease, herpes simplex encephalitis, turner's syndrome, down's syndrome, survivors of low birth weight, schizophrenia, major depression, posttraumatic stress disorder, chronic alcoholism, borderline personality disorder, obsessive-compulsive disorder, and antisocial personality disorder. |
2005-07-15 |
2023-08-12 |
human |
| Jung Lee, Hiroaki Fukumoto, Jennifer Orne, Jochen Klucken, Susan Raju, Charles R Vanderburg, Michael C Irizarry, Bradley T Hyman, Martin Ingelsso. Decreased levels of BDNF protein in Alzheimer temporal cortex are independent of BDNF polymorphisms. Experimental neurology. vol 194. issue 1. 2005-07-15. PMID:15899246. |
levels of brain-derived neurotrophic factor (bdnf) are reduced in specific brain regions in alzheimer's disease (ad) and bdnf gene polymorphisms have been suggested to influence ad risk, hippocampal function, and memory. |
2005-07-15 |
2023-08-12 |
human |
| Lindy E Harrell, Dee S Parsons, Krystyna Kolas. Pro- and anti-apoptotic evidence for cholinergic denervation and hippocampal sympathetic ingrowth in rat dorsal hippocampus. Experimental neurology. vol 194. issue 1. 2005-07-15. PMID:15899255. |
a similar process, in which peripheral noradrenergic axons invade hippocampus, may also occur in alzheimer's disease. |
2005-07-15 |
2023-08-12 |
rat |
| Lindy E Harrell, Dee S Parsons, Krystyna Kolas. Pro- and anti-apoptotic evidence for cholinergic denervation and hippocampal sympathetic ingrowth in rat dorsal hippocampus. Experimental neurology. vol 194. issue 1. 2005-07-15. PMID:15899255. |
since apoptotic cell death has been demonstrated in the selective neuronal loss found in alzheimer's disease, the aim of this study was to measure apoptotic protein expression and dna fragmentation in hippocampal sympathetic ingrowth and cholinergic denervation. |
2005-07-15 |
2023-08-12 |
rat |
| Kazuhiro Honda, Mark A Smith, Xiongwei Zhu, Diane Baus, William C Merrick, Alan M Tartakoff, Thomas Hattier, Peggy L Harris, Sandra L Siedlak, Hisashi Fujioka, Quan Liu, Paula I Moreira, Frank P Miller, Akihiko Nunomura, Shun Shimohama, George Perr. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. The Journal of biological chemistry. vol 280. issue 22. 2005-07-12. PMID:15767256. |
consistent with in situ findings, ribosomes purified from alzheimer hippocampus contained significantly higher levels of rnase-sensitive iron(ii) and redox activity than control. |
2005-07-12 |
2023-08-12 |
rabbit |