| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Monika A Davare, Johannes W Hel. Increased phosphorylation of the neuronal L-type Ca(2+) channel Ca(v)1.2 during aging. Proceedings of the National Academy of Sciences of the United States of America. vol 100. issue 26. 2004-04-20. PMID:14665691. |
the hippocampus is critical for learning and is one of the first brain regions to be affected in alzheimer's disease. |
2004-04-20 |
2023-08-12 |
rat |
| Ya-Ping Lu, Mei Zeng, Dick F Swaab, Rivka Ravid, Jiang-Ning Zho. Colocalization and alteration of estrogen receptor-alpha and -beta in the hippocampus in Alzheimer's disease. Human pathology. vol 35. issue 3. 2004-04-14. PMID:15017582. |
colocalization and alteration of estrogen receptor-alpha and -beta in the hippocampus in alzheimer's disease. |
2004-04-14 |
2023-08-12 |
human |
| Ya-Ping Lu, Mei Zeng, Dick F Swaab, Rivka Ravid, Jiang-Ning Zho. Colocalization and alteration of estrogen receptor-alpha and -beta in the hippocampus in Alzheimer's disease. Human pathology. vol 35. issue 3. 2004-04-14. PMID:15017582. |
the human hippocampus is severely affected in alzheimer's disease (ad). |
2004-04-14 |
2023-08-12 |
human |
| Ming-Chyi Pai, W Jake Jacob. Topographical disorientation in community-residing patients with Alzheimer's disease. International journal of geriatric psychiatry. vol 19. issue 3. 2004-04-13. PMID:15027040. |
based on the hypothesis that declarative memory and navigation ability depend on hippocampal integrity, and the fact that declarative memory declines early in alzheimer's disease (ad), the authors suggest that topographical disorientation (td) will be an early manifestation of ad. |
2004-04-13 |
2023-08-12 |
Not clear |
| Amanda J Mishizen-Eberz, Robert A Rissman, Troy L Carter, Milos D Ikonomovic, Barry B Wolfe, David M Armstron. Biochemical and molecular studies of NMDA receptor subunits NR1/2A/2B in hippocampal subregions throughout progression of Alzheimer's disease pathology. Neurobiology of disease. vol 15. issue 1. 2004-04-07. PMID:14751773. |
biochemical and molecular studies of nmda receptor subunits nr1/2a/2b in hippocampal subregions throughout progression of alzheimer's disease pathology. |
2004-04-07 |
2023-08-12 |
human |
| Amanda J Mishizen-Eberz, Robert A Rissman, Troy L Carter, Milos D Ikonomovic, Barry B Wolfe, David M Armstron. Biochemical and molecular studies of NMDA receptor subunits NR1/2A/2B in hippocampal subregions throughout progression of Alzheimer's disease pathology. Neurobiology of disease. vol 15. issue 1. 2004-04-07. PMID:14751773. |
alzheimer's disease (ad) is characterized by loss of specific cell populations within selective subregions of the hippocampus. |
2004-04-07 |
2023-08-12 |
human |
| Nicholas Lange, Stephen Lake, Reisa Sperling, John Brown, Carol Routledge, Marilyn Albert, Stephan Hecker. Two macroscopic and microscopic brain imaging studies of human hippocampus in early Alzheimer's disease and schizophrenia research. Statistics in medicine. vol 23. issue 2. 2004-03-31. PMID:14716733. |
two macroscopic and microscopic brain imaging studies of human hippocampus in early alzheimer's disease and schizophrenia research. |
2004-03-31 |
2023-08-12 |
human |
| Nicholas Lange, Stephen Lake, Reisa Sperling, John Brown, Carol Routledge, Marilyn Albert, Stephan Hecker. Two macroscopic and microscopic brain imaging studies of human hippocampus in early Alzheimer's disease and schizophrenia research. Statistics in medicine. vol 23. issue 2. 2004-03-31. PMID:14716733. |
among the many diseases that affect the hippocampus, a small yet highly important brain region responsible for memory and identity, alzheimer's disease and schizophrenia are among the most devastating. |
2004-03-31 |
2023-08-12 |
human |
| Nicholas Lange, Stephen Lake, Reisa Sperling, John Brown, Carol Routledge, Marilyn Albert, Stephan Hecker. Two macroscopic and microscopic brain imaging studies of human hippocampus in early Alzheimer's disease and schizophrenia research. Statistics in medicine. vol 23. issue 2. 2004-03-31. PMID:14716733. |
last, we attempt to draw the attention of the biostatistical community interested in imaging neuroscience to the intriguing complexities of human hippocampal research in early alzheimer's disease, schizophrenia and other brain diseases via brain imaging methods. |
2004-03-31 |
2023-08-12 |
human |
| Isidro Ferrer, Isabel Hernández, Berta Puig, María Jesús Rey, Mario Ezquerra, Eduardo Tolosa, Merce Boad. Ubiquitin-negative mini-pick-like bodies in the dentate gyrus in p301l tauopathy. Journal of Alzheimer's disease : JAD. vol 5. issue 6. 2004-03-25. PMID:14757934. |
sarkosyl-insoluble fractions of the hippocampus were enriched in p38-p and gsk-3 beta-p in alzheimer's disease (ad) cases, processed in parallel for comparative purposes, but not in the p310l mutation. |
2004-03-25 |
2023-08-12 |
Not clear |
| Roy G Cutler, Jeremiah Kelly, Kristin Storie, Ward A Pedersen, Anita Tammara, Kimmo Hatanpaa, Juan C Troncoso, Mark P Mattso. Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 7. 2004-03-16. PMID:14970312. |
alzheimer's disease (ad) is an age-related disorder characterized by deposition of amyloid beta-peptide (abeta) and degeneration of neurons in brain regions such as the hippocampus, resulting in progressive cognitive dysfunction. |
2004-03-16 |
2023-08-12 |
Not clear |
| Stephen W Scheff, Douglas A Pric. Synaptic pathology in Alzheimer's disease: a review of ultrastructural studies. Neurobiology of aging. vol 24. issue 8. 2004-03-11. PMID:14643375. |
morphologic studies of the neuropathology in alzheimer's disease (ad) have demonstrated significant loss of synaptic connectivity in many regions of the neocortex and hippocampus. |
2004-03-11 |
2023-08-12 |
Not clear |
| William G Hone. Pathology of presynaptic proteins in Alzheimer's disease: more than simple loss of terminals. Neurobiology of aging. vol 24. issue 8. 2004-03-11. PMID:14643376. |
second, all brain regions in alzheimer's disease do not show equivalent presynaptic protein pathology, hippocampus tended to be most affected. |
2004-03-11 |
2023-08-12 |
mouse |
| R M Camicioli, J R Korzan, S L Foster, N J Fisher, D J Emery, A C Bastos, C C Hanstoc. Posterior cingulate metabolic changes occur in Parkinson's disease patients without dementia. Neuroscience letters. vol 354. issue 3. 2004-03-08. PMID:14700725. |
hippocampal atrophy has been shown in alzheimer's disease (ad) and pd. |
2004-03-08 |
2023-08-12 |
Not clear |
| Nicholas Lang. What can modern statistics offer imaging neuroscience? Statistical methods in medical research. vol 12. issue 5. 2004-03-05. PMID:14599005. |
a key region of interest is the human hippocampus, affected by brain disorders such as alzheimer's disease and schizophrenia. |
2004-03-05 |
2023-08-12 |
human |
| Ming Zhao, Joseph Su, Elizabeth Head, Carl W Cotma. Accumulation of caspase cleaved amyloid precursor protein represents an early neurodegenerative event in aging and in Alzheimer's disease. Neurobiology of disease. vol 14. issue 3. 2004-03-05. PMID:14678756. |
frontal cortex and hippocampal tissue from age-matched control and alzheimer's brains (ad) was used. |
2004-03-05 |
2023-08-12 |
human |
| Kunlin Jin, Alyson L Peel, Xiao Ou Mao, Lin Xie, Barbara A Cottrell, David C Henshall, David A Greenber. Increased hippocampal neurogenesis in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 1. 2004-02-25. PMID:14660786. |
increased hippocampal neurogenesis in alzheimer's disease. |
2004-02-25 |
2023-08-12 |
Not clear |
| Dong-Gyu Jo, Joo-Yong Lee, Yeon-Mi Hong, Sungmin Song, Inhee Mook-Jung, Jae-Young Koh, Yong-Keun Jun. Induction of pro-apoptotic calsenilin/DREAM/KChIP3 in Alzheimer's disease and cultured neurons after amyloid-beta exposure. Journal of neurochemistry. vol 88. issue 3. 2004-02-24. PMID:14720210. |
calsenilin levels were elevated in the cortex region of alzheimer's patient brains and in the neocortex and the hippocampus of swedish mutant beta-amyloid precursor protein transgenic mice brains. |
2004-02-24 |
2023-08-12 |
mouse |
| Dong-Gyu Jo, Joo-Yong Lee, Yeon-Mi Hong, Sungmin Song, Inhee Mook-Jung, Jae-Young Koh, Yong-Keun Jun. Induction of pro-apoptotic calsenilin/DREAM/KChIP3 in Alzheimer's disease and cultured neurons after amyloid-beta exposure. Journal of neurochemistry. vol 88. issue 3. 2004-02-24. PMID:14720210. |
exposing cultured cortical and hippocampal neurons to abeta42, an amyloid-beta peptide whose deposition in the brain is a characteristic of alzheimer's disease, induced both calsenilin protein and mrna expression, and cell death. |
2004-02-24 |
2023-08-12 |
mouse |
| T Järvenpää, M P Laakso, R Rossi, M Koskenvuo, J Kaprio, I Räihä, T Kurki, M Laine, G B Frisoni, J O Rinn. Hippocampal MRI volumetry in cognitively discordant monozygotic twin pairs. Journal of neurology, neurosurgery, and psychiatry. vol 75. issue 1. 2004-02-04. PMID:14707319. |
to investigate whether hippocampal atrophy, a proxy for incipient alzheimer's disease, can be detected in non-demented monozygotic co-twins of demented twins by using volumetric magnetic resonance imaging (mri). |
2004-02-04 |
2023-08-12 |
Not clear |