| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bernadeta Michalski, Margaret Fahnestoc. Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer's disease. Brain research. Molecular brain research. vol 111. issue 1-2. 2003-07-16. PMID:12654514. |
we and others have demonstrated a reduction in bdnf mrna expression in alzheimer's disease hippocampus and cortex, which may help to explain the selective vulnerability of these neurons. |
2003-07-16 |
2023-08-12 |
human |
| Milos D Ikonomovic, Elliott J Mufson, Joanne Wuu, Elizabeth J Cochran, David A Bennett, Steven T DeKosk. Cholinergic plasticity in hippocampus of individuals with mild cognitive impairment: correlation with Alzheimer's neuropathology. Journal of Alzheimer's disease : JAD. vol 5. issue 1. 2003-07-08. PMID:12590165. |
cholinergic plasticity in hippocampus of individuals with mild cognitive impairment: correlation with alzheimer's neuropathology. |
2003-07-08 |
2023-08-12 |
human |
| Milos D Ikonomovic, Elliott J Mufson, Joanne Wuu, Elizabeth J Cochran, David A Bennett, Steven T DeKosk. Cholinergic plasticity in hippocampus of individuals with mild cognitive impairment: correlation with Alzheimer's neuropathology. Journal of Alzheimer's disease : JAD. vol 5. issue 1. 2003-07-08. PMID:12590165. |
hippocampal chat activity levels were also determined in a group of end-stage ad patients who were enrolled in the university of pittsburgh alzheimer's disease research center. |
2003-07-08 |
2023-08-12 |
human |
| Sébastien Weill-Engerer, Jean Philippe David, Véronique Sazdovitch, Philippe Liere, Michael Schumacher, André Delacourte, Etienne Emile Baulieu, Yvette Akw. In vitro metabolism of dehydroepiandrosterone (DHEA) to 7alpha-hydroxy-DHEA and Delta5-androstene-3beta,17beta-diol in specific regions of the aging brain from Alzheimer's and non-demented patients. Brain research. vol 969. issue 1-2. 2003-07-02. PMID:12676372. |
under our experimental conditions, the synthesis of 7alpha-hydroxy-dhea and delta5-androstene-3beta,17beta-diol occurs in the frontal cortex, hippocampus, amygdala, cerebellum and striatum of both alzheimer's patients and non-demented controls. |
2003-07-02 |
2023-08-12 |
human |
| Osamu Yokota, Seishi Terada, Hideki Ishizu, Takeshi Ishihara, Hiroshi Ujike, Hanae Nakashima, Yoshihiko Nakashima, Aki Kugo, Frédéric Checler, Shigetoshi Kurod. Cyclooxygenase-2 in the hippocampus is up-regulated in Alzheimer's disease but not in variant Alzheimer's disease with cotton wool plaques in humans. Neuroscience letters. vol 343. issue 3. 2003-07-02. PMID:12770691. |
cyclooxygenase-2 in the hippocampus is up-regulated in alzheimer's disease but not in variant alzheimer's disease with cotton wool plaques in humans. |
2003-07-02 |
2023-08-12 |
Not clear |
| Osamu Yokota, Seishi Terada, Hideki Ishizu, Takeshi Ishihara, Hiroshi Ujike, Hanae Nakashima, Yoshihiko Nakashima, Aki Kugo, Frédéric Checler, Shigetoshi Kurod. Cyclooxygenase-2 in the hippocampus is up-regulated in Alzheimer's disease but not in variant Alzheimer's disease with cotton wool plaques in humans. Neuroscience letters. vol 343. issue 3. 2003-07-02. PMID:12770691. |
we examined neuronal expression of cyclooxygenase-2, a pro-inflammatory protein, and neuron densities in the ca1-4 of the hippocampus in three cases of alzheimer's disease with cotton wool plaques (cwp-ad), 17 cases of typical alzheimer's disease without cwps (tad), and 26 normal controls. |
2003-07-02 |
2023-08-12 |
Not clear |
| Susan A Farr, William A Banks, Kayoko Uezu, Atsuko Sano, F Spencer Gaskin, John E Morle. Antibody to beta-amyloid protein increases acetylcholine in the hippocampus of 12 month SAMP8 male mice. Life sciences. vol 73. issue 5. 2003-06-26. PMID:12770611. |
abeta is proposed to play an etiological role in alzheimer's disease and to be a cause of the decrease in the level of acetylcholine in the hippocampus. |
2003-06-26 |
2023-08-12 |
mouse |
| K A Josephs, D F Tang Wai, J E Paris. Hippocampal sclerosis in a case of Alzheimer's disease-like dementia with late onset intractable epilepsy. European journal of neurology. vol 10. issue 3. 2003-06-16. PMID:12752417. |
hippocampal sclerosis in a case of alzheimer's disease-like dementia with late onset intractable epilepsy. |
2003-06-16 |
2023-08-12 |
Not clear |
| Alberto Fernández, Juan Arrazola, Fernando Maestú, Carlos Amo, Pedro Gil-Gregorio, Christian Wienbruch, Tomás Orti. Correlations of hippocampal atrophy and focal low-frequency magnetic activity in Alzheimer disease: volumetric MR imaging-magnetoencephalographic study. AJNR. American journal of neuroradiology. vol 24. issue 3. 2003-06-11. PMID:12637301. |
correlations of hippocampal atrophy and focal low-frequency magnetic activity in alzheimer disease: volumetric mr imaging-magnetoencephalographic study. |
2003-06-11 |
2023-08-12 |
Not clear |
| Reiner Beneck. Diffuse Lewy body disease - a clinical syndrome or a disease entity? Journal of neurology. vol 250 Suppl 1. 2003-06-11. PMID:12761635. |
confusingly, a large majority of cases showing typical features of dlbd also present with an alzheimer pathology in the hippocampus and cerebral cortex. |
2003-06-11 |
2023-08-12 |
Not clear |
| M Sárvári, I Vágó, C S Wéber, J Nagy, P Gál, M Mák, J P Kósa, P Závodszky, T Pázmán. Inhibition of C1q-beta-amyloid binding protects hippocampal cells against complement mediated toxicity. Journal of neuroimmunology. vol 137. issue 1-2. 2003-06-03. PMID:12667643. |
these results provide evidence that complement has the potential to damage hippocampal cells, and c1q is a relevant target to suspend this deleterious mechanism in alzheimer's disease. |
2003-06-03 |
2023-08-12 |
rat |
| S Yamaguchi, K Meguro, M Shimada, J Ishizaki, A Yamadori, Y Sekit. Five-year retrospective changes in hippocampal atrophy and cognitive screening test performances in very mild Alzheimer's disease: the Tajiri Project. Neuroradiology. vol 44. issue 1. 2003-05-30. PMID:11942499. |
five-year retrospective changes in hippocampal atrophy and cognitive screening test performances in very mild alzheimer's disease: the tajiri project. |
2003-05-30 |
2023-08-12 |
human |
| Yoshiki Koriyama, Kenzo Chiba, Tetsuro Mohr. Propentofylline protects beta-amyloid protein-induced apoptosis in cultured rat hippocampal neurons. European journal of pharmacology. vol 458. issue 3. 2003-05-20. PMID:12504778. |
beta-amyloid protein 1-42 (beta42) can induce apoptosis in the cultured hippocampal neurons, suggesting that it plays an important role in causing neurodegeneration in alzheimer's disease. |
2003-05-20 |
2023-08-12 |
rat |
| Hyeon-Ju Kim, Kwang-Deog Moon, Dong-Seok Lee, Sang-Han Le. Ethyl ether fraction of Gastrodia elata Blume protects amyloid beta peptide-induced cell death. Journal of ethnopharmacology. vol 84. issue 1. 2003-05-19. PMID:12499082. |
recently, it has been reported that alzheimer's disease is associated with cell death in neuronal cells including the hippocampus. |
2003-05-19 |
2023-08-12 |
Not clear |
| Konstantine K Zakzanis, Simon J Graham, Zachariah Campbel. A meta-analysis of structural and functional brain imaging in dementia of the Alzheimer's type: a neuroimaging profile. Neuropsychology review. vol 13. issue 1. 2003-05-14. PMID:12691498. |
we conducted a quantitative review of the imaging literature using meta-analytic methodology to characterize further the magnitude of hippocampal deficit in probable alzheimer's disease (ad) and to determine whether other neuroanatomic structures in ad can better discriminate the disease from normal aging. |
2003-05-14 |
2023-08-12 |
Not clear |
| Anitha Suram, K S Jagannatha Rao, K S Latha, M A Viswamitr. First evidence to show the topological change of DNA from B-dNA to Z-DNA conformation in the hippocampus of Alzheimer's brain. Neuromolecular medicine. vol 2. issue 3. 2003-05-09. PMID:12622407. |
first evidence to show the topological change of dna from b-dna to z-dna conformation in the hippocampus of alzheimer's brain. |
2003-05-09 |
2023-08-12 |
Not clear |
| Anitha Suram, K S Jagannatha Rao, K S Latha, M A Viswamitr. First evidence to show the topological change of DNA from B-dNA to Z-DNA conformation in the hippocampus of Alzheimer's brain. Neuromolecular medicine. vol 2. issue 3. 2003-05-09. PMID:12622407. |
our studies for the first time showed evidence for altered dna conformation in the hippocampus of alzheimer's disease affected brain. |
2003-05-09 |
2023-08-12 |
Not clear |
| Shailendra Anoopkumar-Dukie, Barbara Lack, Kerry McPhail, Tebello Nyokong, Zaynab Lambat, Deepa Maharaj, Santy Day. Indomethacin reduces lipid peroxidation in rat brain homogenate by binding Fe2+. Metabolic brain disease. vol 18. issue 1. 2003-05-07. PMID:12603077. |
one of the hallmarks of alzheimer's disease (ad) is the progressive degeneration of cholinergic neurons in the cerebral cortex and hippocampus. |
2003-05-07 |
2023-08-12 |
rat |
| M Rose, B Dudas, U Cornelli, I Hani. Protective effect of the heparin-derived oligosaccharide C3, on AF64A-induced cholinergic lesion in rats. Neurobiology of aging. vol 24. issue 3. 2003-04-29. PMID:12600723. |
alzheimer's disease (ad) literature indicates that glycosaminoglycans (gags) may prevent proteoglycan-induced amyloid-beta (abeta) aggregation, decrease abeta-induced tau-2 immunoreactivity, and increase the axonal growth and arborization of hippocampal neurons. |
2003-04-29 |
2023-08-12 |
rat |
| Claire Murphy, Terry L Jernigan, Christine Fennema-Notestin. Left hippocampal volume loss in Alzheimer's disease is reflected in performance on odor identification: a structural MRI study. Journal of the International Neuropsychological Society : JINS. vol 9. issue 3. 2003-04-29. PMID:12666770. |
left hippocampal volume loss in alzheimer's disease is reflected in performance on odor identification: a structural mri study. |
2003-04-29 |
2023-08-12 |
human |