| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stephen M Fitzjohn, Andrew J Doherty, Graham L Collingridg. The use of the hippocampal slice preparation in the study of Alzheimer's disease. European journal of pharmacology. vol 585. issue 1. 2008-10-31. PMID:18423442. |
in the present article we show how studying synaptic mechanisms in hippocampal slice preparations provides information that may be useful in, firstly, the understanding of the aetiology of alzheimer's disease and, secondly, in the development of novel therapies for dementia. |
2008-10-31 |
2023-08-12 |
Not clear |
| V Chauvire, C Even, J Thuile, F Rouillon, J-D Guelf. [Frontotemporal dementia: a review]. L'Encephale. vol 33. issue 6. 2008-10-23. PMID:18789785. |
the pattern of neuropsychological impairment reflects the involvement of the frontal lobe and appears different from that of other degenerative diseases, such as alzheimer's dementia, which involves hippocampal damage. |
2008-10-23 |
2023-08-12 |
Not clear |
| S Kushida, K Kimoto, N Hori, M Toyoda, N Karasawa, T Yamamoto, A Kojo, M Onozuk. Soft-diet feeding decreases dopamine release and impairs aversion learning in Alzheimer model rats. Neuroscience letters. vol 439. issue 2. 2008-10-14. PMID:18514408. |
to examine the effects of soft-diet feeding on the dopaminergic system in a model rat for alzheimer's disease (ad), we measured dopamine release in the hippocampus using a microdialysis approach and assessed learning ability and memory using step-through passive avoidance tests. |
2008-10-14 |
2023-08-12 |
rat |
| C Zhao, K-H Braunewel. Expression of the neuronal calcium sensor visinin-like protein-1 in the rat hippocampus. Neuroscience. vol 153. issue 4. 2008-10-08. PMID:18440708. |
vilip-1 has been implicated in the pathology of cns disorders including alzheimer's disease and schizophrenia, but its expression has also been found to be regulated following induction of hippocampal synaptic plasticity underlying learning and memory processes. |
2008-10-08 |
2023-08-12 |
rat |
| M N Wu, Y X He, F Guo, J S Q. Alpha4beta2 nicotinic acetylcholine receptors are required for the amyloid beta protein-induced suppression of long-term potentiation in rat hippocampal CA1 region in vivo. Brain research bulletin. vol 77. issue 2-3. 2008-10-06. PMID:18602971. |
amyloid beta protein (abeta) is thought to be responsible for the deficit of learning and memory in alzheimer's disease (ad), possibly through interfering with synaptic plasticity such as hippocampal long-term potentiation (ltp). |
2008-10-06 |
2023-08-12 |
rat |
| R S Desikan, B Fischl, H J Cabral, T L Kemper, C R G Guttmann, D Blacker, B T Hyman, M S Albert, R J Killian. MRI measures of temporoparietal regions show differential rates of atrophy during prodromal AD. Neurology. vol 71. issue 11. 2008-10-03. PMID:18672473. |
mri studies have demonstrated differential rates of atrophy in the entorhinal cortex and hippocampus during the prodromal phase of alzheimer disease (ad). |
2008-10-03 |
2023-08-12 |
Not clear |
| Alicia Rubio, Mar Pérez, Luis de Lecea, Jesús Avil. Effect of cortistatin on tau phosphorylation at Ser262 site. Journal of neuroscience research. vol 86. issue 11. 2008-09-30. PMID:18438934. |
the development of intraneuronal lesions as a result of the progressive deposition of hyperphosphorylated tau at specific brain regions (such as hippocampus and cortex) plays a key role in the pathological process of alzheimer's disease. |
2008-09-30 |
2023-08-12 |
mouse |
| Vahram Haroutunian, Michal Schnaider-Beeri, James Schmeidler, Michael Wysocki, Dushyant P Purohit, Daniel P Perl, Leslie S Libow, Gerson T Lesser, Maria Maroukian, Hillel T Grossma. Role of the neuropathology of Alzheimer disease in dementia in the oldest-old. Archives of neurology. vol 65. issue 9. 2008-09-29. PMID:18779425. |
neuritic plaques (nps) and neurofibrillary tangles (nfts) in the brain, especially in the hippocampus, entorhinal cortex, and isocortex, are hallmark lesions of alzheimer disease and dementia in the elderly. |
2008-09-29 |
2023-08-12 |
Not clear |
| G Chételat, M Fouquet, G Kalpouzos, I Denghien, V De la Sayette, F Viader, F Mézenge, B Landeau, J C Baron, F Eustache, B Desgrange. Three-dimensional surface mapping of hippocampal atrophy progression from MCI to AD and over normal aging as assessed using voxel-based morphometry. Neuropsychologia. vol 46. issue 6. 2008-09-24. PMID:18289618. |
the hippocampus is the brain structure of highest and earliest structural alteration in alzheimer's disease (ad). |
2008-09-24 |
2023-08-12 |
Not clear |
| Daniela Hartl, Michael Rohe, Lei Mao, Matthias Staufenbiel, Claus Zabel, Joachim Klos. Impairment of adolescent hippocampal plasticity in a mouse model for Alzheimer's disease precedes disease phenotype. PloS one. vol 3. issue 7. 2008-09-24. PMID:18648492. |
impairment of adolescent hippocampal plasticity in a mouse model for alzheimer's disease precedes disease phenotype. |
2008-09-24 |
2023-08-12 |
mouse |
| Bronwen Martin, Randall Brenneman, Kevin G Becker, Marjan Gucek, Robert N Cole, Stuart Maudsle. iTRAQ analysis of complex proteome alterations in 3xTgAD Alzheimer's mice: understanding the interface between physiology and disease. PloS one. vol 3. issue 7. 2008-09-24. PMID:18648646. |
alzheimer's disease (ad) is characterized by progressive cognitive impairment associated with accumulation of amyloid beta-peptide, synaptic degeneration and the death of neurons in the hippocampus, and temporal, parietal and frontal lobes of the cerebral cortex. |
2008-09-24 |
2023-08-12 |
mouse |
| Philip Thomas, Nathan J O' Callaghan, Michael Fenec. Telomere length in white blood cells, buccal cells and brain tissue and its variation with ageing and Alzheimer's disease. Mechanisms of ageing and development. vol 129. issue 4. 2008-09-19. PMID:18242664. |
however, there was a significantly greater telomere length in hippocampus cells of alzheimer's brains (p = 0.01) compared to control samples (49.0%). |
2008-09-19 |
2023-08-12 |
Not clear |
| Ichiro Nozaki, Takuo Watanabe, Makoto Kawaguchi, Hiroyasu Akatsu, Koichi Tsuneyama, Yasuhiko Yamamoto, Kazuyo Ohe, Hideto Yonekura, Masahito Yamada, Hiroshi Yamamot. Reduced expression of endogenous secretory receptor for advanced glycation endproducts in hippocampal neurons of Alzheimer's disease brains. Archives of histology and cytology. vol 70. issue 5. 2008-09-19. PMID:18431028. |
reduced expression of endogenous secretory receptor for advanced glycation endproducts in hippocampal neurons of alzheimer's disease brains. |
2008-09-19 |
2023-08-12 |
Not clear |
| Jee Hee Lee, Eun Ok Lee, Jihee Lee Kang, Young Hae Chon. Concomitant degradation of beta-catenin and GSK-3 beta potently contributes to glutamate-induced neurotoxicity in rat hippocampal slice cultures. Journal of neurochemistry. vol 106. issue 3. 2008-09-15. PMID:18445133. |
we investigated the molecular mechanism underlying glutamate-induced neurotoxicity in hippocampus, which is primarily linked to cognitive dysfunction in alzheimer's disease. |
2008-09-15 |
2023-08-12 |
rat |
| P Vasudevaraju, Bharathi, R M Garruto, K Sambamurti, K S J Ra. Role of DNA dynamics in Alzheimer's disease. Brain research reviews. vol 58. issue 1. 2008-09-11. PMID:18342372. |
recently, our laboratory discovered the presence of z-dna in the hippocampal region of severely affected alzheimer's disease (ad) brain samples. |
2008-09-11 |
2023-08-12 |
Not clear |
| Ichiro Tsud. [Mathematical structure of episodic memory]. Brain and nerve = Shinkei kenkyu no shinpo. vol 60. issue 7. 2008-09-11. PMID:18646617. |
atrophy of the hippocampus can lead to alzheimer disease. |
2008-09-11 |
2023-08-12 |
rat |
| Ichiro Tsud. [Mathematical structure of episodic memory]. Brain and nerve = Shinkei kenkyu no shinpo. vol 60. issue 7. 2008-09-11. PMID:18646617. |
motivated by the rehabilitation process of alzheimer's patients, we mathematically studied the coding scheme in the hippocampus. |
2008-09-11 |
2023-08-12 |
rat |
| B Desgranges, G Kalpouzos, F Eustach. [Cerebral imaging in healthy aging: contrast with Alzheimer disease]. Revue neurologique. vol 164 Suppl 3. 2008-09-10. PMID:18675034. |
one of the main findings is that the lesser structural deterioration of the anterior hippocampal region, together with the lesser functional alteration of the posterior cingulate cortex, appear to mark the parting of the ways between normal aging and alzheimer's disease, which is characterized by early and prominent deterioration of both structures. |
2008-09-10 |
2023-08-12 |
human |
| B Desgranges, G Kalpouzos, F Eustach. [Cerebral imaging in healthy aging: contrast with Alzheimer disease]. Revue neurologique. vol 164 Suppl 3. 2008-09-10. PMID:18675034. |
frontal areas dysfunction is involved in memory decline in older subjects, at least in some conditions, a finding which clearly contrasts with that found in alzheimer's disease where the hippocampus plays a key role. |
2008-09-10 |
2023-08-12 |
human |
| Li-hong Jiang, Yi-na Zhang, Xiao-wei Wu, Fang-fang Song, Da-yun Gu. Effect of insulin on the cognizing function and expression of hippocampal Abeta1-40 of rat with Alzheimer disease. Chinese medical journal. vol 121. issue 9. 2008-09-09. PMID:18701049. |
effect of insulin on the cognizing function and expression of hippocampal abeta1-40 of rat with alzheimer disease. |
2008-09-09 |
2023-08-12 |
rat |