| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guido Gainotti, Monica Ferraccioli, Maria Gabriella Vita, Camillo Marr. Patterns of neuropsychological impairment in MCI patients with small subcortical infarcts or hippocampal atrophy. Journal of the International Neuropsychological Society : JINS. vol 14. issue 4. 2009-01-15. PMID:18577290. |
we investigated whether mci patients with hippocampal atrophy or multiple subcortical infarcts demonstrate neuropsychological patterns and markers considered typical of alzheimer's disease (ad) and of vascular dementia (vd), respectively. |
2009-01-15 |
2023-08-12 |
Not clear |
| M B H Youdi. Brain iron deficiency and excess; cognitive impairment and neurodegeneration with involvement of striatum and hippocampus. Neurotoxicity research. vol 14. issue 1. 2009-01-13. PMID:18790724. |
the hippocampus is the focus of many studies today, since this brain structure has high zinc concentration and is highly involved in many forms of cognitive deficits as a consequence of cholinergic deficiency and has achieved prominence because of dementia in ageing and alzheimer's disease. |
2009-01-13 |
2023-08-12 |
rat |
| Sebastian Jimenez, David Baglietto-Vargas, Cristina Caballero, Ines Moreno-Gonzalez, Manuel Torres, Raquel Sanchez-Varo, Diego Ruano, Marisa Vizuete, Antonia Gutierrez, Javier Vitoric. Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 45. 2008-12-31. PMID:18987201. |
inflammatory response in the hippocampus of ps1m146l/app751sl mouse model of alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic. |
2008-12-31 |
2023-08-12 |
mouse |
| David C Alsop, Melynda Casement, Cedric de Bazelaire, Tamara Fong, Daniel Z Pres. Hippocampal hyperperfusion in Alzheimer's disease. NeuroImage. vol 42. issue 4. 2008-12-29. PMID:18602481. |
hippocampal hyperperfusion in alzheimer's disease. |
2008-12-29 |
2023-08-12 |
human |
| Rene O Sanchez-Mejia, John W Newman, Sandy Toh, Gui-Qiu Yu, Yungui Zhou, Brian Halabisky, Moustapha Cissé, Kimberly Scearce-Levie, Irene H Cheng, Li Gan, Jorge J Palop, Joseph V Bonventre, Lennart Muck. Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease. Nature neuroscience. vol 11. issue 11. 2008-12-19. PMID:18931664. |
the levels of activated giva-pla(2) in the hippocampus were increased in individuals with alzheimer's disease and in happ mice. |
2008-12-19 |
2023-08-12 |
mouse |
| Yan Chen, Longfei Jia, Cuibai Wei, Fen Wang, Haiyan Lv, Jianping Ji. Association between polymorphisms in the apolipoprotein D gene and sporadic Alzheimer's disease. Brain research. vol 1233. 2008-12-16. PMID:18671953. |
apolipoprotein d (apod) is a lipoprotein-associated glycoprotein that is increased in the hippocampus and cerebrospinal fluid of patients with alzheimer's disease (ad), which implies that apod might be involved in the pathogenesis of ad. |
2008-12-16 |
2023-08-12 |
human |
| Milos D Ikonomovic, Eric E Abrahamson, Tolga Uz, Hari Manev, Steven T Dekosk. Increased 5-lipoxygenase immunoreactivity in the hippocampus of patients with Alzheimer's disease. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 56. issue 12. 2008-12-16. PMID:18678882. |
increased 5-lipoxygenase immunoreactivity in the hippocampus of patients with alzheimer's disease. |
2008-12-16 |
2023-08-12 |
human |
| J G McLarnon, J K Ry. Relevance of abeta1-42 intrahippocampal injection as an animal model of inflamed Alzheimer's disease brain. Current Alzheimer research. vol 5. issue 5. 2008-12-12. PMID:18855589. |
injection of amyloid-beta peptide (abeta1-42) into hippocampal and cortical regions of brain may have utility as an animal model of alzheimer's disease (ad) emphasizing the inflammatory component of disease pathology. |
2008-12-12 |
2023-08-12 |
Not clear |
| Jonathan H Morra, Zhuowen Tu, Liana G Apostolova, Amity E Green, Arthur W Toga, Paul M Thompso. Automatic subcortical segmentation using a contextual model. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. vol 11. issue Pt 1. 2008-12-09. PMID:18979748. |
we trained our algorithm to segment the hippocampus and tested it on 83 brain mris (of 35 alzheimer's disease patients, 22 with mild cognitive impairment, and 26 normal healthy controls). |
2008-12-09 |
2023-08-12 |
Not clear |
| S G Mueller, N Schuff, S Raptentsetsang, J Elman, M W Weine. Selective effect of Apo e4 on CA3 and dentate in normal aging and Alzheimer's disease using high resolution MRI at 4 T. NeuroImage. vol 42. issue 1. 2008-12-08. PMID:18534867. |
selective effect of apo e4 on ca3 and dentate in normal aging and alzheimer's disease using high resolution mri at 4 t. details of the internal hippocampal structure visible at 4 t allow for in vivo volumetry of subfields. |
2008-12-08 |
2023-08-12 |
Not clear |
| Miles C Miller, Rosemarie Tavares, Conrad E Johanson, Virginia Hovanesian, John E Donahue, Liliana Gonzalez, Gerald D Silverberg, Edward G Stop. Hippocampal RAGE immunoreactivity in early and advanced Alzheimer's disease. Brain research. vol 1230. 2008-12-05. PMID:18657529. |
hippocampal rage immunoreactivity in early and advanced alzheimer's disease. |
2008-12-05 |
2023-08-12 |
human |
| Claire Paquet, Nicolas Privat, Rachid Kaci, Marc Polivka, Olivier Dupont, Stéphane Haïk, Jean Louis Laplanche, Jean Jacques Hauw, Françoise Gra. Cerebral amyloid angiopathy with co-localization of prion protein and beta-amyloid in an 85-year-old patient with sporadic Creutzfeldt-Jakob disease. Acta neuropathologica. vol 116. issue 5. 2008-12-02. PMID:18551298. |
alzheimer's type pathology was restricted to a few diffuse beta-amyloid plaques in the entorhinal cortex and rare tangles in the hippocampus. |
2008-12-02 |
2023-08-12 |
Not clear |
| X Zhu, S L Siedlak, Y Wang, G Perry, R J Castellani, M L Cohen, M A Smit. Neuronal binucleation in Alzheimer disease hippocampus. Neuropathology and applied neurobiology. vol 34. issue 4. 2008-11-18. PMID:17995921. |
neuronal binucleation in alzheimer disease hippocampus. |
2008-11-18 |
2023-08-12 |
Not clear |
| Kirsten I Taylor, Alphonse Probs. Anatomic localization of the transentorhinal region of the perirhinal cortex. Neurobiology of aging. vol 29. issue 10. 2008-11-17. PMID:17478012. |
brain imaging measures of entorhinal cortex and hippocampus volumes provide valid and reliable markers of alzheimer's disease (ad). |
2008-11-17 |
2023-08-12 |
Not clear |
| Marie-Caroline Cotel, Thomas A Bayer, Oliver Wirth. Age-dependent loss of dentate gyrus granule cells in APP/PS1KI mice. Brain research. vol 1222. 2008-11-12. PMID:18585693. |
loss of neurons in the hippocampus and other brain regions is, besides the occurrence of plaques and tangles, a neuropathological feature of alzheimer's disease (ad). |
2008-11-12 |
2023-08-12 |
mouse |
| Tamako Misawa, Kunimasa Arima, Hidehiro Mizusawa, Jun-ichi Sato. Close association of water channel AQP1 with amyloid-beta deposition in Alzheimer disease brains. Acta neuropathologica. vol 116. issue 3. 2008-11-10. PMID:18509662. |
to clarify a pathological implication of aqp1 in alzheimer disease (ad), we investigated the possible relationship between amyloid-beta (abeta) deposition and astrocytic aqp1 expression in the motor cortex and hippocampus of 11 ad patients and 16 age-matched other neurological disease cases. |
2008-11-10 |
2023-08-12 |
human |
| Marie-Christine Pardon, Ivan Rattra. What do we know about the long-term consequences of stress on ageing and the progression of age-related neurodegenerative disorders? Neuroscience and biobehavioral reviews. vol 32. issue 6. 2008-11-05. PMID:18436304. |
in an attempt to integrate these findings, a hypothesis is presented here whereby stress, in susceptible individuals, would precipitate age-related cognitive decline and hippocampal integrity during normal and pathological ageing, but will only affect the progression of pathological markers of alzheimer's disease in the presence of other risk factors to this neuropathological disorder. |
2008-11-05 |
2023-08-12 |
human |
| Eun Cheng Suh, Yeon Joo Jung, Yul A Kim, Eun Mi Park, Kyung Eun Le. A beta 25-35 induces presynaptic changes in organotypic hippocampal slice cultures. Neurotoxicology. vol 29. issue 4. 2008-11-05. PMID:18502514. |
memory loss in alzheimer's disease (ad) may be related to synaptic defects in damaged hippocampal neurons. |
2008-11-05 |
2023-08-12 |
Not clear |
| H Dong, C M Yuede, H-S Yoo, M V Martin, C Deal, A G Mace, J G Csernansk. Corticosterone and related receptor expression are associated with increased beta-amyloid plaques in isolated Tg2576 mice. Neuroscience. vol 155. issue 1. 2008-11-05. PMID:18571864. |
previously, we reported that the stress associated with chronic isolation was associated with increased beta-amyloid (abeta) plaque deposition and memory deficits in the tg2576 transgenic animal model of alzheimer's disease (ad) [dong h, goico b, martin m, csernansky ca, bertchume a, csernansky jg (2004) effects of isolation stress on hippocampal neurogenesis, memory, and amyloid plaque deposition in app (tg2576) mutant mice. |
2008-11-05 |
2023-08-12 |
mouse |
| Stephen M Fitzjohn, Andrew J Doherty, Graham L Collingridg. The use of the hippocampal slice preparation in the study of Alzheimer's disease. European journal of pharmacology. vol 585. issue 1. 2008-10-31. PMID:18423442. |
the use of the hippocampal slice preparation in the study of alzheimer's disease. |
2008-10-31 |
2023-08-12 |
Not clear |