| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ryoichi Kimura, Masuo Ohn. Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model. Neurobiology of disease. vol 33. issue 2. 2009-03-09. PMID:19026746. |
although animal models of alzheimer's disease (ad) recapitulate beta-amyloid-dependent hippocampal synaptic and cognitive dysfunctions, it is poorly understood how cortex-dependent remote memory stabilization following initial hippocampal coding is affected. |
2009-03-09 |
2023-08-12 |
mouse |
| Longxuan Li, Imtiaz Rasul, Jun Liu, Bin Zhao, Ronghua Tang, Richard T Premont, William Z Su. Augmented axonal defects and synaptic degenerative changes in female GRK5 deficient mice. Brain research bulletin. vol 78. issue 4-5. 2009-03-06. PMID:18955119. |
recent studies suggested that g protein-coupled receptor kinase 5 (grk5) deficiency plays a significant role in early alzheimer's disease (ad) pathogenesis, and that the grk5 knockout (grk5ko) mouse displays an early alzheimer-like cognitive deficit associated with increased hippocampal axonal defects and synaptic degenerative changes. |
2009-03-06 |
2023-08-12 |
mouse |
| Inga Kadish, Olivier Thibault, Eric M Blalock, Kuey-C Chen, John C Gant, Nada M Porter, Philip W Landfiel. Hippocampal and cognitive aging across the lifespan: a bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 6. 2009-03-06. PMID:19211887. |
multiple hippocampal processes and cognitive functions change with aging or alzheimer's disease, but the potential triggers of these aging cascades are not well understood. |
2009-03-06 |
2023-08-12 |
rat |
| Jun Ming Wang, Roberta Diaz Brinto. Allopregnanolone-induced rise in intracellular calcium in embryonic hippocampal neurons parallels their proliferative potential. BMC neuroscience. vol 9 Suppl 2. 2009-03-04. PMID:19090984. |
we previously demonstrated that the neurosteroid allopregnanolone (apalpha; 5alpha-pregnan-3alpha-ol-20-one) promotes neural progenitor proliferation in vitro in cultures of rodent hippocampal and human cortical neural progenitors, and in vivo in triple transgenic alzheimer's disease mice dentate gyrus. |
2009-03-04 |
2023-08-12 |
mouse |
| I González, J Arévalo-Serrano, J L Pérez, P Gonzalo, A Gonzalo-Rui. Effects of beta-amyloid peptide on the density of M2 muscarinic acetylcholine receptor protein in the hippocampus of the rat: relationship with GABA-, calcium-binding protein and somatostatin-containing cells. Neuropathology and applied neurobiology. vol 34. issue 5. 2009-03-03. PMID:18221260. |
the deposition of amyloid peptides (a beta) in the cortex and hippocampus is the primary trigger of alzheimer's disease (ad). |
2009-03-03 |
2023-08-12 |
rat |
| Claudio Babiloni, Giovanni B Frisoni, Michela Pievani, Fabrizio Vecchio, Roberta Lizio, Maura Buttiglione, Cristina Geroldi, Claudia Fracassi, Fabrizio Eusebi, Raffaele Ferri, Paolo M Rossin. Hippocampal volume and cortical sources of EEG alpha rhythms in mild cognitive impairment and Alzheimer disease. NeuroImage. vol 44. issue 1. 2009-03-03. PMID:18805495. |
hippocampal volume and cortical sources of eeg alpha rhythms in mild cognitive impairment and alzheimer disease. |
2009-03-03 |
2023-08-12 |
human |
| Claudio Babiloni, Giovanni B Frisoni, Michela Pievani, Fabrizio Vecchio, Roberta Lizio, Maura Buttiglione, Cristina Geroldi, Claudia Fracassi, Fabrizio Eusebi, Raffaele Ferri, Paolo M Rossin. Hippocampal volume and cortical sources of EEG alpha rhythms in mild cognitive impairment and Alzheimer disease. NeuroImage. vol 44. issue 1. 2009-03-03. PMID:18805495. |
atrophy of hippocampus and alteration of resting eyes-closed electroencephalographic (eeg) rhythms represent important features of mild cognitive impairment (mci) and alzheimer's disease (ad). |
2009-03-03 |
2023-08-12 |
human |
| James J Choi, Shougang Wang, Truman R Brown, Scott A Small, Karen E K Duff, Elisa E Konofago. Noninvasive and transient blood-brain barrier opening in the hippocampus of Alzheimer's double transgenic mice using focused ultrasound. Ultrasonic imaging. vol 30. issue 3. 2009-03-03. PMID:19149463. |
noninvasive and transient blood-brain barrier opening in the hippocampus of alzheimer's double transgenic mice using focused ultrasound. |
2009-03-03 |
2023-08-12 |
mouse |
| James J Choi, Shougang Wang, Truman R Brown, Scott A Small, Karen E K Duff, Elisa E Konofago. Noninvasive and transient blood-brain barrier opening in the hippocampus of Alzheimer's double transgenic mice using focused ultrasound. Ultrasonic imaging. vol 30. issue 3. 2009-03-03. PMID:19149463. |
in conclusion, a bbb-impermeable molecule was noninvasively, transiently and reproducibly delivered to the hippocampus of alzheimer's app/ps1 mice. |
2009-03-03 |
2023-08-12 |
mouse |
| Jens M Theysohn, O Kraff, S Maderwald, M U Schlamann, A de Greiff, M Forsting, S C Ladd, M E Ladd, E R Gizewsk. The human hippocampus at 7 T--in vivo MRI. Hippocampus. vol 19. issue 1. 2009-02-27. PMID:18727048. |
the human hippocampus plays a central role in various neuropsychiatric disorders, such as temporal lobe epilepsy (tle), alzheimer's dementia, mild cognitive impairment, and schizophrenia. |
2009-02-27 |
2023-08-12 |
human |
| Nobuyoshi Fukumitsu, Kenji Ishii, Yuichi Kimura, Keiichi Oda, Masaya Hashimoto, Masahiko Suzuki, Kiichi Ishiwat. Adenosine A(1) receptors using 8-dicyclopropylmethyl-1-[(11)C]methyl-3-propylxanthine PET in Alzheimer's disease. Annals of nuclear medicine. vol 22. issue 10. 2009-02-27. PMID:19142702. |
decreased density of adenosine a1 receptors, which is a major subtype adenosine receptor in the hippocampus, has been reported in vitro in alzheimer's disease. |
2009-02-27 |
2023-08-12 |
human |
| Xinhua Zhang, Guohua Jin, Lei Wang, Wenzhong Hu, Meiling Tian, Jianbing Qin, Huiwei Huan. Brn-4 is upregulated in the deafferented hippocampus and promotes neuronal differentiation of neural progenitors in vitro. Hippocampus. vol 19. issue 2. 2009-02-26. PMID:18831054. |
fimbria-fornix (ff), the septo-hippocampal pathway, was transected to model alzheimer's disease (ad), which is characterized by loss of cholinergic afferent fibers in hippocampus. |
2009-02-26 |
2023-08-12 |
Not clear |
| Yoko Uchida, Hiroshi Takahash. Rapid detection of Abeta deposits in APP transgenic mice by Hoechst 33342. Neuroscience letters. vol 448. issue 3. 2009-02-24. PMID:18955112. |
the accumulation of beta-amyloid (abeta) is the earliest event seen in the neocortex and hippocampus of alzheimer's disease (ad) patients. |
2009-02-24 |
2023-08-12 |
mouse |
| Grégoria Kalpouzos, Gaël Chételat, Jean-Claude Baron, Brigitte Landeau, Katell Mevel, Christine Godeau, Louisa Barré, Jean-Marc Constans, Fausto Viader, Francis Eustache, Béatrice Desgrange. Voxel-based mapping of brain gray matter volume and glucose metabolism profiles in normal aging. Neurobiology of aging. vol 30. issue 1. 2009-02-19. PMID:17630048. |
furthermore, the lesser affected anterior hippocampal region, together with the lesser functional alteration of the posterior cingulate cortex, appear to mark the parting of the ways between normal aging and alzheimer's disease, which is characterized by early and prominent deterioration of both structures. |
2009-02-19 |
2023-08-12 |
human |
| Henny Wati, Takeshi Kawarabayashi, Etsuro Matsubara, Ayumi Kasai, Takae Hirasawa, Takeo Kubota, Yasuo Harigaya, Mikio Shoji, Shuichiro Maed. Transthyretin accelerates vascular Abeta deposition in a mouse model of Alzheimer's disease. Brain pathology (Zurich, Switzerland). vol 19. issue 1. 2009-02-19. PMID:18429966. |
it was reported that the lack of neurodegeneration in a transgenic mouse model of alzheimer's disease (ad) (tg2576 mouse) was associated with increased ttr level in the hippocampus, and that chronic infusion of anti-ttr antibody into the hippocampus of tg2576 mice led to increased local abeta deposits, tau hyperphosphorylation and apoptosis. |
2009-02-19 |
2023-08-12 |
mouse |
| Luis Escribano, Ana-María Simón, Alberto Pérez-Mediavilla, Pablo Salazar-Colocho, Joaquín Del Río, Diana Frechill. Rosiglitazone reverses memory decline and hippocampal glucocorticoid receptor down-regulation in an Alzheimer's disease mouse model. Biochemical and biophysical research communications. vol 379. issue 2. 2009-02-13. PMID:19109927. |
rosiglitazone reverses memory decline and hippocampal glucocorticoid receptor down-regulation in an alzheimer's disease mouse model. |
2009-02-13 |
2023-08-12 |
mouse |
| Muralikrishnan Dhanasekaran, Leigh A Holcomb, Angie R Hitt, Binu Tharakan, Jami W Porter, Keith A Young, Bala V Manya. Centella asiatica extract selectively decreases amyloid beta levels in hippocampus of Alzheimer's disease animal model. Phytotherapy research : PTR. vol 23. issue 1. 2009-02-11. PMID:19048607. |
centella asiatica extract selectively decreases amyloid beta levels in hippocampus of alzheimer's disease animal model. |
2009-02-11 |
2023-08-12 |
mouse |
| Fedde van der Lijn, Tom den Heijer, Monique M B Breteler, Wiro J Niesse. Hippocampus segmentation in MR images using atlas registration, voxel classification, and graph cuts. NeuroImage. vol 43. issue 4. 2009-02-10. PMID:18761411. |
since hippocampal volume has been found to be an early biomarker for alzheimer's disease, there is large interest in automated methods to accurately, robustly, and reproducibly extract the hippocampus from mri data. |
2009-02-10 |
2023-08-12 |
Not clear |
| Laura A Craig, Nancy S Hong, Joelle Kopp, Robert J McDonal. Reduced cholinergic status in hippocampus produces spatial memory deficits when combined with kainic acid induced seizures. Hippocampus. vol 18. issue 11. 2009-02-09. PMID:18651618. |
one of these risk factors commonly associated with alzheimer's disease is the loss of cholinergic neurons of the medial septum that project to the hippocampus, leading to depletion in cholinergic activity. |
2009-02-09 |
2023-08-12 |
rat |
| Ralf Tepest, Lei Wang, John G Csernansky, Philip Neubert, Reinhard Heun, Lukas Scheef, Frank Jesse. Hippocampal surface analysis in subjective memory impairment, mild cognitive impairment and Alzheimer's dementia. Dementia and geriatric cognitive disorders. vol 26. issue 4. 2009-02-09. PMID:18841017. |
hippocampal surface analysis in subjective memory impairment, mild cognitive impairment and alzheimer's dementia. |
2009-02-09 |
2023-08-12 |
Not clear |