| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohammad Haris, Erin McArdle, Matthew Fenty, Anup Singh, Christos Davatzikos, John Q Trojanowski, Elias R Melhem, Christopher M Clark, Arijitt Borthaku. Early marker for Alzheimer's disease: hippocampus T1rho (T(1rho)) estimation. Journal of magnetic resonance imaging : JMRI. vol 29. issue 5. 2009-05-28. PMID:19388096. |
early marker for alzheimer's disease: hippocampus t1rho (t(1rho)) estimation. |
2009-05-28 |
2023-08-12 |
Not clear |
| Mohammad Haris, Erin McArdle, Matthew Fenty, Anup Singh, Christos Davatzikos, John Q Trojanowski, Elias R Melhem, Christopher M Clark, Arijitt Borthaku. Early marker for Alzheimer's disease: hippocampus T1rho (T(1rho)) estimation. Journal of magnetic resonance imaging : JMRI. vol 29. issue 5. 2009-05-28. PMID:19388096. |
to evaluate the t1rho (t(1rho)) mri relaxation time in hippocampus in the brain of alzheimer's disease (ad), mild cognitive impairment (mci), and control, and to determine whether the t(1rho) shows any significant difference between these cohorts. |
2009-05-28 |
2023-08-12 |
Not clear |
| Dirk T Leube, Susanne Weis, Kathrin Freymann, Michael Erb, Frank Jessen, Reinhard Heun, Wolfgang Grodd, Tilo T Kirche. Neural correlates of verbal episodic memory in patients with MCI and Alzheimer's disease--a VBM study. International journal of geriatric psychiatry. vol 23. issue 11. 2009-05-21. PMID:18449954. |
hippocampal atrophy is a hallmark feature of alzheimer's disease (ad). |
2009-05-21 |
2023-08-12 |
human |
| J B Brewer, S Magda, C Airriess, M E Smit. Fully-automated quantification of regional brain volumes for improved detection of focal atrophy in Alzheimer disease. AJNR. American journal of neuroradiology. vol 30. issue 3. 2009-05-21. PMID:19112065. |
this note describes tests of a fully automated mr imaging postprocessing system for volumetric analysis of structures (such as the hippocampus) known to be affected in early alzheimer disease (ad). |
2009-05-21 |
2023-08-12 |
Not clear |
| Shu-xiu Zhu, Guo-jie Su. [Effects of electroacupuncture on learning and memory ability and glial cells of the hippocampus in the rat of Alzheimer disease]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 29. issue 2. 2009-05-21. PMID:19391539. |
[effects of electroacupuncture on learning and memory ability and glial cells of the hippocampus in the rat of alzheimer disease]. |
2009-05-21 |
2023-08-12 |
rat |
| T A Ishunina, D F Swaa. Hippocampal estrogen receptor-alpha splice variant TADDI in the human brain in aging and Alzheimer's disease. Neuroendocrinology. vol 89. issue 2. 2009-05-19. PMID:18815440. |
hippocampal estrogen receptor-alpha splice variant taddi in the human brain in aging and alzheimer's disease. |
2009-05-19 |
2023-08-12 |
human |
| Gemma Molinaro, Giuseppe Battaglia, Barbara Riozzi, Luisa Di Menna, Liborio Rampello, Valeria Bruno, Ferdinando Nicolett. Memantine treatment reduces the expression of the K(+)/Cl(-) cotransporter KCC2 in the hippocampus and cerebral cortex, and attenuates behavioural responses mediated by GABA(A) receptor activation in mice. Brain research. vol 1265. 2009-05-13. PMID:19236854. |
), a drug that is currently prescribed for the treatment of alzheimer's disease, increased the levels of brain-derived neurotrophic factor (bdnf) and reduced the expression of the neuron-specific k(+)/cl(-) co-transporter, kcc2, in the hippocampus and cerebral cortex of mice. |
2009-05-13 |
2023-08-12 |
mouse |
| Jonathan H Morra, Zhuowen Tu, Liana G Apostolova, Amity E Green, Christina Avedissian, Sarah K Madsen, Neelroop Parikshak, Arthur W Toga, Clifford R Jack, Norbert Schuff, Michael W Weiner, Paul M Thompso. Automated mapping of hippocampal atrophy in 1-year repeat MRI data from 490 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls. NeuroImage. vol 45. issue 1 Suppl. 2009-05-12. PMID:19041724. |
automated mapping of hippocampal atrophy in 1-year repeat mri data from 490 subjects with alzheimer's disease, mild cognitive impairment, and elderly controls. |
2009-05-12 |
2023-08-12 |
human |
| Jonathan H Morra, Zhuowen Tu, Liana G Apostolova, Amity E Green, Christina Avedissian, Sarah K Madsen, Neelroop Parikshak, Arthur W Toga, Clifford R Jack, Norbert Schuff, Michael W Weiner, Paul M Thompso. Automated mapping of hippocampal atrophy in 1-year repeat MRI data from 490 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls. NeuroImage. vol 45. issue 1 Suppl. 2009-05-12. PMID:19041724. |
as one of the earliest structures to degenerate in alzheimer's disease (ad), the hippocampus is the target of many studies of factors that influence rates of brain degeneration in the elderly. |
2009-05-12 |
2023-08-12 |
human |
| Jonathan H Morra, Zhuowen Tu, Liana G Apostolova, Amity E Green, Christina Avedissian, Sarah K Madsen, Neelroop Parikshak, Arthur W Toga, Clifford R Jack, Norbert Schuff, Michael W Weiner, Paul M Thompso. Automated mapping of hippocampal atrophy in 1-year repeat MRI data from 490 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls. NeuroImage. vol 45. issue 1 Suppl. 2009-05-12. PMID:19041724. |
hippocampal loss rates can be rapidly mapped, and they track cognitive decline closely enough to be used as surrogate markers of alzheimer's disease in drug trials. |
2009-05-12 |
2023-08-12 |
human |
| Anqi Qiu, Christine Fennema-Notestine, Anders M Dale, Michael I Mille. Regional shape abnormalities in mild cognitive impairment and Alzheimer's disease. NeuroImage. vol 45. issue 3. 2009-05-12. PMID:19280688. |
we assessed the surface deformation of seven structures (amygdala, hippocampus, thalamus, caudate, putamen, globus pallidus, body and temporal horn of the lateral ventricles) in 383 mri volumes, based on data shared through the publicly available alzheimer's disease neuroimaging initiative (adni), to identify regionally-specific shape abnormalities in mci and ad. |
2009-05-12 |
2023-08-12 |
human |
| Hai-Yan Hu, Qiong Meng, Zhe Jiang, Wei-Ming Zhu, Wen-Hua Eang, Xiao-Yan Zhan. [Effect of Qingxin Kaiqiao fang on learning and memory ability and morphology of hippocampal nerve cells in AD mice]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 33. issue 10. 2009-05-11. PMID:18720873. |
to study the effect of the qingxin kaiqiao fang on learning and memory ability and shape hippocampal nerve cells in alzheimer disease (ad). |
2009-05-11 |
2023-08-12 |
mouse |
| Pei-Ning Wang, Hsiu-Chih Liu, Jiing-Feng Lirng, Ker-Neng Lin, Zin-An W. Accelerated hippocampal atrophy rates in stable and progressive amnestic mild cognitive impairment. Psychiatry research. vol 171. issue 3. 2009-05-11. PMID:19217759. |
studies suggest that smaller hippocampal volume predicts alzheimer's disease (ad) in mild cognitive impairment (mci). |
2009-05-11 |
2023-08-12 |
human |
| CongJian Zhao, Rene Anand, Karl-Heinz Braunewel. Nicotine-induced Ca2+-myristoyl switch of neuronal Ca2+ sensor VILIP-1 in hippocampal neurons: a possible crosstalk mechanism for nicotinic receptors. Cellular and molecular neurobiology. vol 29. issue 2. 2009-05-08. PMID:18925431. |
the nachrs are associated with processes of synaptic plasticity in hippocampal neurons and they have been implicated in the pathology of cns disorders, including alzheimer's disease and schizophrenia. |
2009-05-08 |
2023-08-12 |
Not clear |
| Peter Wostyn, Kurt Audenaert, Peter Paul De Dey. The Valsalva maneuver and Alzheimer's disease: is there a link? Current Alzheimer research. vol 6. issue 1. 2009-05-08. PMID:19199876. |
in this paper, we discuss three hypotheses about the mechanisms by which extensive use of the valsalva maneuver might contribute to the neuropathogenesis of alzheimer's disease: via mechanical stress-induced events in the hippocampus and/or via changes in the secretory process of the choroid plexus and/or via hemodynamic changes in cerebral blood flow. |
2009-05-08 |
2023-08-12 |
Not clear |
| Kevin Duerson, Randall L Woltjer, Paramita Mookherjee, James B Leverenz, Thomas J Montine, Thomas D Bird, David V Pow, Thomas Rauen, David G Coo. Detergent-insoluble EAAC1/EAAT3 aberrantly accumulates in hippocampal neurons of Alzheimer's disease patients. Brain pathology (Zurich, Switzerland). vol 19. issue 2. 2009-05-01. PMID:18624794. |
detergent-insoluble eaac1/eaat3 aberrantly accumulates in hippocampal neurons of alzheimer's disease patients. |
2009-05-01 |
2023-08-12 |
human |
| Jeroen J M Hoozemans, Elise S van Haastert, Diana A T Nijholt, Annemieke J M Rozemuller, Piet Eikelenboom, Wiep Schepe. The unfolded protein response is activated in pretangle neurons in Alzheimer's disease hippocampus. The American journal of pathology. vol 174. issue 4. 2009-04-28. PMID:19264902. |
the unfolded protein response is activated in pretangle neurons in alzheimer's disease hippocampus. |
2009-04-28 |
2023-08-12 |
Not clear |
| Karunya K Kandimalla, Olenych G Scott, Smita Fulzele, Michael W Davidson, Joseph F Podusl. Mechanism of neuronal versus endothelial cell uptake of Alzheimer's disease amyloid beta protein. PloS one. vol 4. issue 2. 2009-04-27. PMID:19247480. |
alzheimer's disease (ad) is characterized by significant neurodegeneration in the cortex and hippocampus; intraneuronal tangles of hyperphosphorylated tau protein; and accumulation of beta-amyloid (abeta) proteins 40 and 42 in the brain parenchyma as well as in the cerebral vasculature. |
2009-04-27 |
2023-08-12 |
mouse |
| Madhav Thambisetty, Abdul Hye, Catherine Foy, Eileen Daly, Amanda Glover, Allison Cooper, Andrew Simmons, Declan Murphy, Simon Loveston. Proteome-based identification of plasma proteins associated with hippocampal metabolism in early Alzheimer's disease. Journal of neurology. vol 255. issue 11. 2009-04-20. PMID:19156487. |
proteome-based identification of plasma proteins associated with hippocampal metabolism in early alzheimer's disease. |
2009-04-20 |
2023-08-12 |
Not clear |
| Stéphane Bastianetto, Yvan Dumont, Yingshan Han, Rémi Quirio. Comparative neuroprotective properties of stilbene and catechin analogs: action via a plasma membrane receptor site? CNS neuroscience & therapeutics. vol 15. issue 1. 2009-04-15. PMID:19228181. |
for example, we have shown that resveratrol, a polyphenol enriched in red wine and other foods such as peanuts, protects hippocampal cells against beta-amyloid (abeta)-induced toxicity, a key protein involved in the neuropathology of alzheimer disease. |
2009-04-15 |
2023-08-12 |
rat |