| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M F Beal, M F Mazurek, C N Svendsen, E D Bird, J B Marti. Widespread reduction of somatostatin-like immunoreactivity in the cerebral cortex in Alzheimer's disease. Annals of neurology. vol 20. issue 4. 1986-12-29. PMID:3789664. |
widespread reduction of somatostatin-like immunoreactivity in the cerebral cortex in alzheimer's disease. |
1986-12-29 |
2023-08-11 |
Not clear |
| M F Beal, M F Mazurek, C N Svendsen, E D Bird, J B Marti. Widespread reduction of somatostatin-like immunoreactivity in the cerebral cortex in Alzheimer's disease. Annals of neurology. vol 20. issue 4. 1986-12-29. PMID:3789664. |
although several studies have documented reduced concentrations of somatostatin-like immunoreactivity (sli) in the cerebral cortex in alzheimer's disease, there is controversy concerning the extent and importance of these changes. |
1986-12-29 |
2023-08-11 |
Not clear |
| M F Beal, M F Mazurek, C N Svendsen, E D Bird, J B Marti. Widespread reduction of somatostatin-like immunoreactivity in the cerebral cortex in Alzheimer's disease. Annals of neurology. vol 20. issue 4. 1986-12-29. PMID:3789664. |
widespread reductions of sli in alzheimer's disease cerebral cortex were found, with the most profound changes seen in temporal lobe; but there also were major reductions in both the frontal and occipital cortex. |
1986-12-29 |
2023-08-11 |
Not clear |
| D W Ellison, M F Beal, M F Mazurek, E D Bird, J B Marti. A postmortem study of amino acid neurotransmitters in Alzheimer's disease. Annals of neurology. vol 20. issue 5. 1986-12-24. PMID:2878639. |
these results suggest that gamma-aminobutyric acidergic neurons in alzheimer's cerebral cortex may be selectively vulnerable to the disease process. |
1986-12-24 |
2023-08-11 |
Not clear |
| M F Beal, J B Marti. Neuropeptides in neurological disease. Annals of neurology. vol 20. issue 5. 1986-12-24. PMID:2947536. |
we describe the normal anatomy of neuropeptides in both the cerebral cortex and basal ganglia as a framework for interpreting neuropeptide alterations in alzheimer's disease (ad), huntington's disease, and parkinson's disease. |
1986-12-24 |
2023-08-11 |
Not clear |
| D Dawbarn, M N Rossor, C Q Mountjoy, M Roth, P C Emso. Decreased somatostatin immunoreactivity but not neuropeptide Y immunoreactivity in cerebral cortex in senile dementia of Alzheimer type. Neuroscience letters. vol 70. issue 1. 1986-12-17. PMID:2877420. |
decreased somatostatin immunoreactivity but not neuropeptide y immunoreactivity in cerebral cortex in senile dementia of alzheimer type. |
1986-12-17 |
2023-08-11 |
Not clear |
| D Dawbarn, M N Rossor, C Q Mountjoy, M Roth, P C Emso. Decreased somatostatin immunoreactivity but not neuropeptide Y immunoreactivity in cerebral cortex in senile dementia of Alzheimer type. Neuroscience letters. vol 70. issue 1. 1986-12-17. PMID:2877420. |
no difference was observed in npy-li between alzheimer cerebral cortex and control cortex. |
1986-12-17 |
2023-08-11 |
Not clear |
| D D Flynn, D C Mas. Characterization of L-[3H]nicotine binding in human cerebral cortex: comparison between Alzheimer's disease and the normal. Journal of neurochemistry. vol 47. issue 6. 1986-12-17. PMID:3772387. |
characterization of l-[3h]nicotine binding in human cerebral cortex: comparison between alzheimer's disease and the normal. |
1986-12-17 |
2023-08-11 |
human |
| D D Flynn, D C Mas. Characterization of L-[3H]nicotine binding in human cerebral cortex: comparison between Alzheimer's disease and the normal. Journal of neurochemistry. vol 47. issue 6. 1986-12-17. PMID:3772387. |
samples of infratemporal cortex (brodmann area 38) from patients with alzheimer's disease had a 50% reduction in the number of l-[3h]nicotine sites. |
1986-12-17 |
2023-08-11 |
human |
| P D Gorevic, F Goñi, B Pons-Estel, F Alvarez, N S Peress, B Frangion. Isolation and partial characterization of neurofibrillary tangles and amyloid plaque core in Alzheimer's disease: immunohistological studies. Journal of neuropathology and experimental neurology. vol 45. issue 6. 1986-11-25. PMID:3772397. |
fractions enriched in neurofibrillary tangles (nft) and amyloid fibrils were isolated from the cerebral cortex of three cases of senile dementia of the alzheimer type. |
1986-11-25 |
2023-08-11 |
Not clear |
| M F Beal, M F Mazurek, G K Chattha, C N Svendsen, E D Bird, J B Marti. Neuropeptide Y immunoreactivity is reduced in cerebral cortex in Alzheimer's disease. Annals of neurology. vol 20. issue 3. 1986-11-18. PMID:3767313. |
neuropeptide y immunoreactivity is reduced in cerebral cortex in alzheimer's disease. |
1986-11-18 |
2023-08-11 |
Not clear |
| M F Beal, M F Mazurek, G K Chattha, C N Svendsen, E D Bird, J B Marti. Neuropeptide Y immunoreactivity is reduced in cerebral cortex in Alzheimer's disease. Annals of neurology. vol 20. issue 3. 1986-11-18. PMID:3767313. |
further study of the selective vulnerability of these neurons in alzheimer's disease cortex may provide clues to the nature of the underlying disease process. |
1986-11-18 |
2023-08-11 |
Not clear |
| V M Vostriko. [Electron-cytochemical study of acetylcholinesterase in the cerebral cortex in Alzheimer's disease]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). vol 86. issue 7. 1986-11-07. PMID:3765981. |
[electron-cytochemical study of acetylcholinesterase in the cerebral cortex in alzheimer's disease]. |
1986-11-07 |
2023-08-11 |
Not clear |
| V M Vostriko. [Electron-cytochemical study of acetylcholinesterase in the cerebral cortex in Alzheimer's disease]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). vol 86. issue 7. 1986-11-07. PMID:3765981. |
the disclosed cytochemical changes confirm the presence of disorders in the cholinergic system in the brain cortex in alzheimer's disease. |
1986-11-07 |
2023-08-11 |
Not clear |
| J A Edwardson, J Klinowski, A E Oakley, R H Perry, J M Cand. Aluminosilicates and the ageing brain: implications for the pathogenesis of Alzheimer's disease. Ciba Foundation symposium. vol 121. 1986-10-23. PMID:3743229. |
present at low densities in the cerebral cortex of most aged individuals, they occur in large numbers in alzheimer's disease, the major form of senile dementia. |
1986-10-23 |
2023-08-11 |
Not clear |
| C M Yates, I Laszlo, G Fink, I Hastings, J Boyd, K Jame. Monoclonal antibodies to human hypoglossal nucleus which stain neurons and astrocytes in normal brains and brains from cases of Alzheimer-type dementia. Neuroscience. vol 18. issue 1. 1986-09-17. PMID:2426629. |
this antibody also stained the numerous glial fibrillary acidic protein-positive astrocytes in alzheimer cerebral cortex, but did not stain glial fibrillary acidic protein-positive astrocytes in the white matter of brains from controls or cases of alzheimer-type dementia. |
1986-09-17 |
2023-08-11 |
human |
| C M Yates, I Laszlo, G Fink, I Hastings, J Boyd, K Jame. Monoclonal antibodies to human hypoglossal nucleus which stain neurons and astrocytes in normal brains and brains from cases of Alzheimer-type dementia. Neuroscience. vol 18. issue 1. 1986-09-17. PMID:2426629. |
the staining pattern of es.19 suggests that fibrous astrocytes in alzheimer cerebral cortex are antigenically different from fibrous astrocytes in white matter. |
1986-09-17 |
2023-08-11 |
human |
| S Gomez, J Puymirat, P Valade, P Davous, P Rondot, P Cohe. Patients with Alzheimer's disease show an increased content of 15 Kdalton somatostatin precursor and a lowered level of tetradecapeptide in their cerebrospinal fluid. Life sciences. vol 39. issue 7. 1986-09-17. PMID:2874467. |
they are discussed in connection with others suggesting that alzheimer's patients may be selectively altered in their somatostatinergic neurones of their cerebral cortex (morrison et al. |
1986-09-17 |
2023-08-11 |
Not clear |
| F Plu. The pathophysiology of dementia. Gerontology. vol 32 Suppl 1. 1986-09-17. PMID:3732820. |
alzheimer's disease presently is the commonest cause in the developed world, causing a cortical-subcortical degeneration of ascending cholinergic neurons and large pyramidal cells in the cerebral cortex. |
1986-09-17 |
2023-08-11 |
Not clear |
| P Q Sumpter, D M Mann, C A Davies, P O Yates, J S Snowden, D Near. An ultrastructural analysis of the effects of accumulation of neurofibrillary tangle in pyramidal neurons of the cerebral cortex in Alzheimer's disease. Neuropathology and applied neurobiology. vol 12. issue 3. 1986-09-17. PMID:3736776. |
an ultrastructural analysis of the effects of accumulation of neurofibrillary tangle in pyramidal neurons of the cerebral cortex in alzheimer's disease. |
1986-09-17 |
2023-08-11 |
Not clear |