| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J H Morrison, D A Lewis, M J Campbell, G W Huntley, D L Benson, C Boura. A monoclonal antibody to non-phosphorylated neurofilament protein marks the vulnerable cortical neurons in Alzheimer's disease. Brain research. vol 416. issue 2. 1987-10-22. PMID:3113670. |
a monoclonal antibody to non-phosphorylated neurofilament protein labels a distinct subset of pyramidal cells in the normal human cortex which have a distribution very similar to that of neurofibrillary tangles in brains from patients with alzheimer's disease. |
1987-10-22 |
2023-08-11 |
human |
| K Fujiyoshi, H Suga, K Okamoto, S Nakamura, M Kameyam. Reduction of arginine-vasopressin in the cerebral cortex in Alzheimer type senile dementia. Journal of neurology, neurosurgery, and psychiatry. vol 50. issue 7. 1987-10-22. PMID:3625218. |
reduction of arginine-vasopressin in the cerebral cortex in alzheimer type senile dementia. |
1987-10-22 |
2023-08-11 |
Not clear |
| S Kuroda, S Otsuki, Y Hayash. Diffuse Lewy body disease: an autopsy case. Acta medica Okayama. vol 41. issue 3. 1987-10-16. PMID:2820201. |
autopsy revealed numerous senile plaques in the cerebral cortex and alzheimer's neurofibrillary tangles in the inferior temporal lobe and hippocampus. |
1987-10-16 |
2023-08-11 |
Not clear |
| B T Hyman, G W Van Hoesen, A R Damasi. Alzheimer's disease: glutamate depletion in the hippocampal perforant pathway zone. Annals of neurology. vol 22. issue 1. 1987-09-30. PMID:2443073. |
its cells of origin, in the entorhinal cortex, are destroyed in alzheimer's disease. |
1987-09-30 |
2023-08-11 |
human |
| D M Mann, P O Yates, B Marcyniuk, C R Ravindr. Loss of neurones from cortical and subcortical areas in Down's syndrome patients at middle age. Quantitative comparisons with younger Down's patients and patients with Alzheimer's disease. Journal of the neurological sciences. vol 80. issue 1. 1987-09-18. PMID:2956368. |
brains were examined after autopsy from 12 patients over 53 years of age with down's syndrome (in whose brains plaques and tangles were numerous in many areas of cortex and subcortex), 3 patients under 53 years of age with down's syndrome (in whose brains plaques and tangles were minimal or absent), 10 patients, of age range similar to the older down's group but with alzheimer's disease and 5 control patients of age range similar to the younger down's group. |
1987-09-18 |
2023-08-11 |
Not clear |
| A Delacourte, A Defossez, P Persuy, M C Peer. Observation of morphological relationships between angiopathic blood vessels and degenerative neurites in Alzheimer's disease. Virchows Archiv. A, Pathological anatomy and histopathology. vol 411. issue 3. 1987-09-10. PMID:2441514. |
using simultaneous histochemical and immunohistochemical labellings on the same tissue sections of alzheimer cortex (association cortex and hippocampus), the different lesions were stained with great sensitivity and specificity. |
1987-09-10 |
2023-08-11 |
Not clear |
| D C German, C L White, D R Sparkma. Alzheimer's disease: neurofibrillary tangles in nuclei that project to the cerebral cortex. Neuroscience. vol 21. issue 2. 1987-09-01. PMID:3302759. |
alzheimer's disease: neurofibrillary tangles in nuclei that project to the cerebral cortex. |
1987-09-01 |
2023-08-11 |
Not clear |
| D C German, C L White, D R Sparkma. Alzheimer's disease: neurofibrillary tangles in nuclei that project to the cerebral cortex. Neuroscience. vol 21. issue 2. 1987-09-01. PMID:3302759. |
sections were examined from the cerebral cortex, diencephalon, midbrain and pons in seven alzheimer's and three age-matched normal brains. |
1987-09-01 |
2023-08-11 |
Not clear |
| D C German, C L White, D R Sparkma. Alzheimer's disease: neurofibrillary tangles in nuclei that project to the cerebral cortex. Neuroscience. vol 21. issue 2. 1987-09-01. PMID:3302759. |
the antibody sensitively stained the many tangles, and senile plaques, in the cerebral cortex of the alzheimer's brains and the few tangles and senile plaques in the aged normal cortex. |
1987-09-01 |
2023-08-11 |
Not clear |
| D C German, C L White, D R Sparkma. Alzheimer's disease: neurofibrillary tangles in nuclei that project to the cerebral cortex. Neuroscience. vol 21. issue 2. 1987-09-01. PMID:3302759. |
these data indicate that alzheimer's disease is a disease of the cerebral cortex and the numerous subcortical nuclei which diffusely innervate it, and are consistent with the hypothesis that the cerebral cortex is the primary target of the disease and the interconnected subcortical nuclei are secondarily affected due to retrograde transport of a cortical pathogen or failure of normal transport of a trophic agent. |
1987-09-01 |
2023-08-11 |
Not clear |
| R L Doty, P F Reyes, T Grego. Presence of both odor identification and detection deficits in Alzheimer's disease. Brain research bulletin. vol 18. issue 5. 1987-08-28. PMID:3607528. |
recent studies of alzheimer's disease patients have demonstrated (a) marked structural and biochemical alterations in brain regions associated with olfactory function (including the olfactory bulb and entorhinal cortex) and (b) decrements in the ability to identify odorants. |
1987-08-28 |
2023-08-11 |
Not clear |
| E G Gray, M Paula-Barbosa, A Rohe. Alzheimer's disease: paired helical filaments and cytomembranes. Neuropathology and applied neurobiology. vol 13. issue 2. 1987-08-28. PMID:3614544. |
observations were made with the electron microscope on biopsies from the frontal cerebral cortex of four patients showing the clinical symptoms of advanced alzheimer's disease (ad). |
1987-08-28 |
2023-08-11 |
Not clear |
| K J Reinikainen, P J Riekkinen, T Halonen, M Laaks. Decreased muscarinic receptor binding in cerebral cortex and hippocampus in Alzheimer's disease. Life sciences. vol 41. issue 4. 1987-08-20. PMID:3600187. |
decreased muscarinic receptor binding in cerebral cortex and hippocampus in alzheimer's disease. |
1987-08-20 |
2023-08-11 |
Not clear |
| A B MacDonald, J M Mirand. Concurrent neocortical borreliosis and Alzheimer's disease. Human pathology. vol 18. issue 7. 1987-08-19. PMID:3297997. |
borrelia spirochetes were directly visualized in autopsy brain tissue from a patient with alzheimer's disease and were cultured from cerebral cortex in artificial media. |
1987-08-19 |
2023-08-11 |
Not clear |
| F Fazekas, J B Chawluk, A Alavi, H I Hurtig, R A Zimmerma. MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging. AJR. American journal of roentgenology. vol 149. issue 2. 1987-08-17. PMID:3496763. |
areas of high signal intensity affecting hippocampal and sylvian cortex were also present in five alzheimer and two multiinfarct dementia patients, but absent in controls. |
1987-08-17 |
2023-08-11 |
human |
| M Nieto-Sampedr. Astrocyte mitogenic activity in aged normal and Alzheimer's human brain. Neurobiology of aging. vol 8. issue 3. 1987-08-10. PMID:3600955. |
a 1.3-fold increase in specific mitogenic activity was observed in extracts from alzheimer's disease cortex when compared to normal aged or adult tissue. |
1987-08-10 |
2023-08-11 |
human |
| B T Hyman, L J Kromer, G W Van Hoese. Reinnervation of the hippocampal perforant pathway zone in Alzheimer's disease. Annals of neurology. vol 21. issue 3. 1987-08-07. PMID:3606033. |
the results suggest that in alzheimer's disease sprouting of ache-containing systems occurs in the hippocampal formation in response to disease-related cellular damage in the entorhinal cortex. |
1987-08-07 |
2023-08-11 |
Not clear |
| M F Beal, M F Mazure. Substance P-like immunoreactivity is reduced in Alzheimer's disease cerebral cortex. Neurology. vol 37. issue 7. 1987-07-31. PMID:2439949. |
substance p-like immunoreactivity is reduced in alzheimer's disease cerebral cortex. |
1987-07-31 |
2023-08-11 |
human |
| K Koshimura, T Kato, I Yohyama, S Nakamura, M Kameyam. Correlation of choline acetyltransferase activity between the nucleus basalis of Meynert and the cerebral cortex. Neuroscience research. vol 4. issue 4. 1987-07-29. PMID:3601249. |
choline acetyltransferase (chat) activities were measured in the cerebral cortex and the nucleus basalis of meynert (nbm) of post-mortem human brains from 8 cases with alzheimer type dementia (atd) and 5 age-matched control subjects. |
1987-07-29 |
2023-08-11 |
human |
| D M Mann, P Q Sumpter, C A Davies, P O Yate. Glycogen accumulations in the cerebral cortex in Alzheimer's disease. Acta neuropathologica. vol 73. issue 2. 1987-07-24. PMID:3037842. |
glycogen accumulations in the cerebral cortex in alzheimer's disease. |
1987-07-24 |
2023-08-11 |
Not clear |