| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S A Johnson, G M Pasinetti, P C May, P A Ponte, B Cordell, C E Finc. Selective reduction of mRNA for the beta-amyloid precursor protein that lacks a Kunitz-type protease inhibitor motif in cortex from Alzheimer brains. Experimental neurology. vol 102. issue 2. 1988-12-21. PMID:2460367. |
in poly(a) rna from cerebral cortex obtained postmortem from victims of alzheimer's disease (ad), an alternatively spliced mrna for the amyloid precursor protein (app-695 mrna) was shown to be decreased by 65%. |
1988-12-21 |
2023-08-11 |
Not clear |
| M F Beal, R A Clevens, G K Chattha, U M MacGarvey, M F Mazurek, S M Gabrie. Galanin-like immunoreactivity is unchanged in Alzheimer's disease and Parkinson's disease dementia cerebral cortex. Journal of neurochemistry. vol 51. issue 6. 1988-12-20. PMID:2460590. |
galanin-like immunoreactivity is unchanged in alzheimer's disease and parkinson's disease dementia cerebral cortex. |
1988-12-20 |
2023-08-11 |
human |
| M F Beal, R A Clevens, G K Chattha, U M MacGarvey, M F Mazurek, S M Gabrie. Galanin-like immunoreactivity is unchanged in Alzheimer's disease and Parkinson's disease dementia cerebral cortex. Journal of neurochemistry. vol 51. issue 6. 1988-12-20. PMID:2460590. |
in the present study, galanin-like immunoreactivity was measured in the postmortem cerebral cortex and hippocampus of 10 controls and 14 patients who had had alzheimer's disease. |
1988-12-20 |
2023-08-11 |
human |
| M L Orlov. [Angioarchitectonics of the cerebral cortex and the hemato-encephalic barrier in Alzheimer's disease]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). vol 88. issue 7. 1988-12-16. PMID:2461014. |
[angioarchitectonics of the cerebral cortex and the hemato-encephalic barrier in alzheimer's disease]. |
1988-12-16 |
2023-08-11 |
human |
| M L Orlov. [Angioarchitectonics of the cerebral cortex and the hemato-encephalic barrier in Alzheimer's disease]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). vol 88. issue 7. 1988-12-16. PMID:2461014. |
the brain cortex angioarchitectonics and blood-brain barrier were considerably altered in alzheimer disease. |
1988-12-16 |
2023-08-11 |
human |
| V M Vostriko, T P Kliushnik, G Sh Burbaev. [Immunohistochemical detection of fibrous astrocytes using an antiserum to glial fibrillary acidic protein in the cerebral cortex in Alzheimer's disease]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). vol 88. issue 7. 1988-12-16. PMID:3142195. |
[immunohistochemical detection of fibrous astrocytes using an antiserum to glial fibrillary acidic protein in the cerebral cortex in alzheimer's disease]. |
1988-12-16 |
2023-08-11 |
Not clear |
| I N Bogolepov. [Cytoarchitectonic characteristics of the fields of the human cerebral cortex in Alzheimer's disease and senile dementia]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). vol 88. issue 7. 1988-12-16. PMID:3188773. |
[cytoarchitectonic characteristics of the fields of the human cerebral cortex in alzheimer's disease and senile dementia]. |
1988-12-16 |
2023-08-11 |
human |
| J P Kesslak, C W Cotman, H C Chui, S Van den Noort, H Fang, R Pfeffer, G Lync. Olfactory tests as possible probes for detecting and monitoring Alzheimer's disease. Neurobiology of aging. vol 9. issue 4. 1988-11-30. PMID:3185859. |
the results of the alzheimer's group are similar to recent animal studies that have shown lesions of the piriform-entorhinal cortex produce a variety of memory deficits that are particularly acute in tasks involving novel odors. |
1988-11-30 |
2023-08-11 |
human |
| J Rogers, J Luber-Narod, S D Styren, W H Civi. Expression of immune system-associated antigens by cells of the human central nervous system: relationship to the pathology of Alzheimer's disease. Neurobiology of aging. vol 9. issue 4. 1988-11-30. PMID:3263583. |
we have previously shown that this marker is profusely expressed in cortex of elderly and alzheimer's disease (ad) patients, as is the receptor for the lymphokine interleukin-2. |
1988-11-30 |
2023-08-11 |
human |
| C Whitford, J Candy, J Edwardson, R Perr. Cortical somatostatinergic system not affected in Alzheimer's and Parkinson's diseases. Journal of the neurological sciences. vol 86. issue 1. 1988-11-04. PMID:2902199. |
a reduction in the levels of somatostatin-like immunoreactivity (sli) and somatostatin binding sites in the cerebral cortex has been previously reported to occur in alzheimer's disease (ad) and parkinson's disease with associated dementia. |
1988-11-04 |
2023-08-11 |
Not clear |
| E Birecree, W O Whetsell, C Stoscheck, L E King, L B Nanne. Immunoreactive epidermal growth factor receptors in neuritic plaques from patients with Alzheimer's disease. Journal of neuropathology and experimental neurology. vol 47. issue 5. 1988-11-01. PMID:3049945. |
alzheimer's disease (ad) is characterized neuropathologically by the presence of neuritic plaques (np) in cerebral cortex and hippocampus, as well as intraneuronal neurofibrillary tangles and granulovacuolar degeneration. |
1988-11-01 |
2023-08-11 |
Not clear |
| R E Majocha, F M Benes, J L Reifel, A M Rodenrys, C A Marott. Laminar-specific distribution and infrastructural detail of amyloid in the Alzheimer disease cortex visualized by computer-enhanced imaging of epitopes recognized by monoclonal antibodies. Proceedings of the National Academy of Sciences of the United States of America. vol 85. issue 16. 1988-10-05. PMID:2457908. |
laminar-specific distribution and infrastructural detail of amyloid in the alzheimer disease cortex visualized by computer-enhanced imaging of epitopes recognized by monoclonal antibodies. |
1988-10-05 |
2023-08-11 |
Not clear |
| M Parent, A Delacourte, A Défossez, B Hémon, K K Han, H Peti. [Alzheimer's disease: study of the distribution of tau proteins constituting helical filament pairs in human central nervous tissue]. Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. vol 306. issue 13. 1988-09-30. PMID:3136867. |
the normal cortical distribution of tau in the human brain correlates well with the distribution of histological lesions that contain phf (neurofibrillary tangles and neuritic plaques) in the alzheimer cortex. |
1988-09-30 |
2023-08-11 |
human |
| D R McLachlan, W J Lukiw, L Wong, C Bergeron, N T Bech-Hanse. Selective messenger RNA reduction in Alzheimer's disease. Brain research. vol 427. issue 3. 1988-09-22. PMID:3401702. |
the anomalous low abundance of neuron specific nf-l mrna, coding for the lowest molecular weight moiety of neurofilament proteins, in cerebral cortex of alzheimer's disease cannot be adequately accounted for by a non-specific effect of brain damage, neuron cell loss or neurons with neurofibrillary degeneration. |
1988-09-22 |
2023-08-11 |
Not clear |
| A M Palmer, G C Stratmann, A W Procter, D M Bowe. Possible neurotransmitter basis of behavioral changes in Alzheimer's disease. Annals of neurology. vol 23. issue 6. 1988-09-16. PMID:2457353. |
serotonin, 5-hydroxyindoleacetic acid, and homovanillic acid concentrations have been determined in 10 areas of the cerebral cortex from 17 subjects with alzheimer's disease and 18 control subjects. |
1988-09-16 |
2023-08-11 |
human |
| D M Mann, B Marcyniuk, P O Yates, D Neary, J S Snowde. The progression of the pathological changes of Alzheimer's disease in frontal and temporal neocortex examined both at biopsy and at autopsy. Neuropathology and applied neurobiology. vol 14. issue 3. 1988-09-15. PMID:3405392. |
these data show that both the clinical and the pathological progression of alzheimer's disease is marked by a continuing loss of pyramidal cells from frontal and temporal cortex, although the densities of plaques and tangles within the cortex do not, per se, correlate with the stage of the illness. |
1988-09-15 |
2023-08-11 |
Not clear |
| S L Lowe, P T Francis, A W Procter, A M Palmer, A N Davison, D M Bowe. Gamma-aminobutyric acid concentration in brain tissue at two stages of Alzheimer's disease. Brain : a journal of neurology. vol 111 ( Pt 4). 1988-09-09. PMID:3401683. |
the concentration of the inhibitory neurotransmitter, gamma-aminobutyric acid (gaba), was measured in the cerebral cortex obtained at diagnostic craniotomy from 10 patients with alzheimer's disease of 3 yrs mean duration and 6 patients with other causes of dementia, and from 31 subjects undergoing other neurosurgical procedures (for which removal of apparently normal tissue was necessary). |
1988-09-09 |
2023-08-11 |
human |
| S L Lowe, P T Francis, A W Procter, A M Palmer, A N Davison, D M Bowe. Gamma-aminobutyric acid concentration in brain tissue at two stages of Alzheimer's disease. Brain : a journal of neurology. vol 111 ( Pt 4). 1988-09-09. PMID:3401683. |
gaba content of 5 areas of the cerebral cortex and the cerebellar cortex was measured postmortem in the brains of 23 alzheimer and 19 control subjects and 5 patients with other causes of dementia. |
1988-09-09 |
2023-08-11 |
human |
| J Chapman, O Bachar, A D Korczyn, E Wertman, D M Michaelso. Antibodies to cholinergic neurons in Alzheimer's disease. Journal of neurochemistry. vol 51. issue 2. 1988-08-24. PMID:3292704. |
alzheimer's disease (ad) is associated with degenerative changes in nuclei of the basal forebrain which provide most of the cholinergic input to the cortex and hippocampus and with a reduction in presynaptic cholinergic parameters in these areas. |
1988-08-24 |
2023-08-11 |
human |
| C M Thompson, W R Markesbery, W D Ehmann, Y X Mao, D E Vanc. Regional brain trace-element studies in Alzheimer's disease. Neurotoxicology. vol 9. issue 1. 1988-08-23. PMID:3393299. |
alzheimer's disease (ad) brain trace-element imbalances in the amygdala, hippocampus and nucleus basalis of meynert (nbm) are found in most cases to be consistent with those previously reported in samples derived principally from ad cerebral cortex (ehmann et al., 1986). |
1988-08-23 |
2023-08-11 |
Not clear |