| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nicolai Franzmeier, Jinyi Ren, Alexander Damm, Gemma Monté-Rubio, Mercè Boada, Agustín Ruiz, Alfredo Ramirez, Frank Jessen, Emrah Düzel, Octavio Rodríguez Gómez, Tammie Benzinger, Alison Goate, Celeste M Karch, Anne M Fagan, Eric McDade, Katharina Buerger, Johannes Levin, Marco Duering, Martin Dichgans, Marc Suárez-Calvet, Christian Haass, Brian A Gordon, Yen Ying Lim, Colin L Masters, Daniel Janowitz, Cihan Catak, Steffen Wolfsgruber, Michael Wagner, Esther Milz, Sonia Moreno-Grau, Stefan Teipel, Michel J Grothe, Ingo Kilimann, Martin Rossor, Nick Fox, Christoph Laske, Jasmeer Chhatwal, Peter Falkai, Robert Perneczky, Jae-Hong Lee, Annika Spottke, Henning Boecker, Frederic Brosseron, Klaus Fliessbach, Michael T Heneka, Peter Nestor, Oliver Peters, Manuel Fuentes, Felix Menne, Josef Priller, Eike J Spruth, Christiana Franke, Anja Schneider, Christine Westerteicher, Oliver Speck, Jens Wiltfang, Claudia Bartels, Miguel Ángel Araque Caballero, Coraline Metzger, Daniel Bittner, Stephen Salloway, Adrian Danek, Jason Hassenstab, Igor Yakushev, Peter R Schofield, John C Morris, Randall J Bateman, Michael Ewer. The BDNF Molecular psychiatry. vol 26. issue 2. 2021-05-14. PMID:30899092. |
the bdnf in alzheimer's disease (ad), a single-nucleotide polymorphism in the gene encoding brain-derived neurotrophic factor (bdnf |
2021-05-14 |
2023-08-13 |
Not clear |
| Yukiko Mori, Mayumi Tsuji, Tatsunori Oguchi, Kensaku Kasuga, Atsushi Kimura, Akinori Futamura, Azusa Sugimoto, Hideyo Kasai, Takeshi Kuroda, Satoshi Yano, Sotaro Hieda, Yuji Kiuchi, Takeshi Ikeuchi, Kenjiro On. Serum BDNF as a Potential Biomarker of Alzheimer's Disease: Verification Through Assessment of Serum, Cerebrospinal Fluid, and Medial Temporal Lobe Atrophy. Frontiers in neurology. vol 12. 2021-05-13. PMID:33967943. |
serum bdnf as a potential biomarker of alzheimer's disease: verification through assessment of serum, cerebrospinal fluid, and medial temporal lobe atrophy. |
2021-05-13 |
2023-08-13 |
human |
| Cynthia M Stonnington, Stefanie N Velgos, Yinghua Chen, Sameena Syed, Matt Huentelman, Pradeep Thiyyagura, Wendy Lee, Ryan Richholt, Richard J Caselli, Dona E C Locke, Bai Lu, Eric M Reiman, Yi Su, Kewei Che. Interaction Between BDNF Val66Met and APOE4 on Biomarkers of Alzheimer's Disease and Cognitive Decline. Journal of Alzheimer's disease : JAD. vol 78. issue 2. 2021-05-07. PMID:33044176. |
interaction between bdnf val66met and apoe4 on biomarkers of alzheimer's disease and cognitive decline. |
2021-05-07 |
2023-08-13 |
Not clear |
| Cynthia M Stonnington, Stefanie N Velgos, Yinghua Chen, Sameena Syed, Matt Huentelman, Pradeep Thiyyagura, Wendy Lee, Ryan Richholt, Richard J Caselli, Dona E C Locke, Bai Lu, Eric M Reiman, Yi Su, Kewei Che. Interaction Between BDNF Val66Met and APOE4 on Biomarkers of Alzheimer's Disease and Cognitive Decline. Journal of Alzheimer's disease : JAD. vol 78. issue 2. 2021-05-07. PMID:33044176. |
whether brain-derived neurotrophic factor (bdnf) met carriage impacts the risk or progression of alzheimer's disease (ad) is unknown. |
2021-05-07 |
2023-08-13 |
Not clear |
| Chiara Braschi, Simona Capsoni, Roberta Narducci, Andrea Poli, Gabriele Sansevero, Rossella Brandi, Lamberto Maffei, Antonino Cattaneo, Nicoletta Berard. Intranasal delivery of BDNF rescues memory deficits in AD11 mice and reduces brain microgliosis. Aging clinical and experimental research. vol 33. issue 5. 2021-04-30. PMID:32676979. |
a decrease in brain-derived neurotrophic factor (bdnf), a neurotrophin essential for synaptic function, plasticity and neuronal survival, is evident early in the progression of alzheimer's disease (ad), being apparent in subjects with mild cognitive impairment or mild ad, and both probdnf and mature bdnf levels are positively correlated with cognitive measures. |
2021-04-30 |
2023-08-13 |
mouse |
| Katerina Cechova, Ross Andel, Francesco Angelucci, Zuzana Chmatalova, Hana Markova, Jan Laczó, Martin Vyhnalek, Vaclav Matoska, Vojtech Kaplan, Zuzana Nedelska, David D Ward, Jakub Hor. Impact of APOE and BDNF Val66Met Gene Polymorphisms on Cognitive Functions in Patients with Amnestic Mild Cognitive Impairment. Journal of Alzheimer's disease : JAD. vol 73. issue 1. 2021-04-19. PMID:31771052. |
apolipoprotein (apoe) ɛ4 is a well-known risk factor for late-onset alzheimer's disease (ad), but other ad-related gene polymorphisms might also be important, such as the polymorphism within the brain-derived neurotrophic factor (bdnf) gene. |
2021-04-19 |
2023-08-13 |
Not clear |
| Luca Colucci-D'Amato, Luisa Speranza, Floriana Volpicell. Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in Depression, Neurodegeneration and Brain Cancer. International journal of molecular sciences. vol 21. issue 20. 2021-04-16. PMID:33096634. |
moreover, we will review data that illustrate the role of bdnf as a potent protective factor that is able to confer protection against neurodegeneration, in particular in alzheimer's disease. |
2021-04-16 |
2023-08-13 |
Not clear |
| Feng Wang, Xi-Xi Wei, Lian-Sheng Chang, Lei Dong, Yong-Ling Wang, Na-Na L. Ultrasound Combined With Microbubbles Loading BDNF Retrovirus to Open BloodBrain Barrier for Treatment of Alzheimer's Disease. Frontiers in pharmacology. vol 12. 2021-03-23. PMID:33746754. |
ultrasound combined with microbubbles loading bdnf retrovirus to open bloodbrain barrier for treatment of alzheimer's disease. |
2021-03-23 |
2023-08-13 |
Not clear |
| Chia-Hao Fan, Chia-Wei Lin, Hei-Jen Huang, Guey-Jen Lee-Chen, Ying-Chieh Sun, Wenwei Lin, Chiung-Mei Chen, Kuo-Hsuan Chang, Ming-Tsan Su, Hsiu Mei Hsieh-L. LMDS-1, a potential TrkB receptor agonist provides a safe and neurotrophic effect for early-phase Alzheimer's disease. Psychopharmacology. vol 237. issue 10. 2021-01-12. PMID:32748031. |
the levels of bdnf and trkb receptor were reduced in patients with alzheimer's disease (ad). |
2021-01-12 |
2023-08-13 |
Not clear |
| Valentina Bessi, Salvatore Mazzeo, Silvia Bagnoli, Sonia Padiglioni, Marco Carraro, Irene Piaceri, Laura Bracco, Sandro Sorbi, Benedetta Nacmia. The implication of BDNF Val66Met polymorphism in progression from subjective cognitive decline to mild cognitive impairment and Alzheimer's disease: a 9-year follow-up study. European archives of psychiatry and clinical neuroscience. vol 270. issue 4. 2020-11-30. PMID:31560105. |
the implication of bdnf val66met polymorphism in progression from subjective cognitive decline to mild cognitive impairment and alzheimer's disease: a 9-year follow-up study. |
2020-11-30 |
2023-08-13 |
human |
| Valentina Bessi, Salvatore Mazzeo, Silvia Bagnoli, Sonia Padiglioni, Marco Carraro, Irene Piaceri, Laura Bracco, Sandro Sorbi, Benedetta Nacmia. The implication of BDNF Val66Met polymorphism in progression from subjective cognitive decline to mild cognitive impairment and Alzheimer's disease: a 9-year follow-up study. European archives of psychiatry and clinical neuroscience. vol 270. issue 4. 2020-11-30. PMID:31560105. |
brain-derived natriuretic factor (bdnf) val66met polymorphism has been frequently reported to be associated with alzheimer's disease (ad) with contrasting results. |
2020-11-30 |
2023-08-13 |
human |
| Kamal Niaz, Syed Zahid Ali Shah, Fazlullah Khan, Mohammed Bul. Ochratoxin A-induced genotoxic and epigenetic mechanisms lead to Alzheimer disease: its modulation with strategies. Environmental science and pollution research international. vol 27. issue 36. 2020-11-26. PMID:32424756. |
ota administration activates various mechanisms such as p38 mapk, jnks, and erks dysfunctions, bdnf disruption, th overexpression, caspase-3 and 9 activation, and erk-1/2 phosphorylation which ultimately lead to alzheimer disease (ad) progression. |
2020-11-26 |
2023-08-13 |
Not clear |
| Bing Xie, Huimin Zhou, Wenxuan Liu, Weifang Yu, Zanchao Liu, Lei Jiang, Rui Zhang, Dongsheng Cui, Zhongli Shi, Shunjiang X. Evaluation of the diagnostic value of peripheral BDNF levels for Alzheimer's disease and mild cognitive impairment: results of a meta-analysis. The International journal of neuroscience. vol 130. issue 3. 2020-11-02. PMID:31518516. |
evaluation of the diagnostic value of peripheral bdnf levels for alzheimer's disease and mild cognitive impairment: results of a meta-analysis. |
2020-11-02 |
2023-08-13 |
human |
| Bing Xie, Huimin Zhou, Wenxuan Liu, Weifang Yu, Zanchao Liu, Lei Jiang, Rui Zhang, Dongsheng Cui, Zhongli Shi, Shunjiang X. Evaluation of the diagnostic value of peripheral BDNF levels for Alzheimer's disease and mild cognitive impairment: results of a meta-analysis. The International journal of neuroscience. vol 130. issue 3. 2020-11-02. PMID:31518516. |
deregulation of brain-derived neurotrophic factor (bdnf) is a possible contributor to the pathology and symptoms of alzheimer's disease (ad). |
2020-11-02 |
2023-08-13 |
human |
| Mamoru Fukuch. Identifying inducers of BDNF gene expression from pharmacologically validated compounds; antipyretic drug dipyrone increases BDNF mRNA in neurons. Biochemical and biophysical research communications. vol 524. issue 4. 2020-10-26. PMID:32059848. |
low levels of brain-derived neurotrophic factor (bdnf), a key regulator of synaptic plasticity, are associated with neurological diseases, including depression and alzheimer's disease. |
2020-10-26 |
2023-08-13 |
Not clear |
| Min-Kyoo Shin, Min-Suk Choi, Hyang-Ji Chae, Ji-Won Kim, Hong-Gi Kim, Kil-Lyong Ki. Ganglioside GQ1b ameliorates cognitive impairments in an Alzheimer's disease mouse model, and causes reduction of amyloid precursor protein. Scientific reports. vol 9. issue 1. 2020-10-15. PMID:31186474. |
brain-derived neurotrophic factor (bdnf) plays crucial roles in memory impairments including alzheimer's disease (ad). |
2020-10-15 |
2023-08-13 |
mouse |
| Manuela Bomba, Alberto Granzotto, Vanessa Castelli, Marco Onofrj, Rossano Lattanzio, Annamaria Cimini, Stefano L Sens. Exenatide Reverts the High-Fat-Diet-Induced Impairment of BDNF Signaling and Inflammatory Response in an Animal Model of Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 70. issue 3. 2020-10-09. PMID:31256135. |
exenatide reverts the high-fat-diet-induced impairment of bdnf signaling and inflammatory response in an animal model of alzheimer's disease. |
2020-10-09 |
2023-08-13 |
mouse |
| Yoshiyasu Fukuyama, Miwa Kubo, Kenichi Harad. The search for, and chemistry and mechanism of, neurotrophic natural products. Journal of natural medicines. vol 74. issue 4. 2020-10-06. PMID:32643028. |
neurotrophic factors, now termed neurotrophins, which belong to a class of polypeptidyl agents, have been shown to potentially be beneficial for the treatment of neurodegenerative diseases such as alzheimer's disease, because endogenous neurotrophic factors (ngf, bdnf, nt3, nt4) have been recognized to play critical roles in the promotion of neurogenesis, differentiation, and neuroprotection throughout the development of the central nervous system. |
2020-10-06 |
2023-08-13 |
rat |
| Henrique Cerqueira Guimarães, Paulo Caramelli, Patricia Paes Araujo Fialho, Elisa de Paula França, Marcelo Pelizzaro Dias Afonso, Antonio Lucio Teixeir. Serum levels of soluble TNF-α receptors but not BDNF are associated with apathy symptoms in mild Alzheimer's disease and amnestic mild cognitive impairment. Dementia & neuropsychologia. vol 7. issue 3. 2020-10-01. PMID:29213854. |
serum levels of soluble tnf-α receptors but not bdnf are associated with apathy symptoms in mild alzheimer's disease and amnestic mild cognitive impairment. |
2020-10-01 |
2023-08-13 |
Not clear |
| Sara R Tanqueiro, Rita M Ramalho, Tiago M Rodrigues, Luísa V Lopes, Ana M Sebastião, Maria J Diógene. Inhibition of NMDA Receptors Prevents the Loss of BDNF Function Induced by Amyloid β. Frontiers in pharmacology. vol 9. 2020-10-01. PMID:29695962. |
in alzheimer's disease (ad), bdnf signaling is known to be impaired, partially because amyloid β (aβ) induces truncation of bdnf main receptor, trkb-full length (trkb-fl). |
2020-10-01 |
2023-08-13 |
Not clear |