| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ted Kheng Siang Ng, Christina Coughlan, Patricia C Heyn, Alex Tagawa, James J Carollo, Ee Heok Kua, Rathi Mahendra. Increased plasma brain-derived neurotrophic factor (BDNF) as a potential biomarker for and compensatory mechanism in mild cognitive impairment: a case-control study. Aging. vol 13. issue 19. 2021-11-02. PMID:34607976. |
previous meta-analyses examining the continuum of alzheimer's disease (ad) concluded significantly decreased peripheral brain-derived neurotrophic factor (bdnf) in ad. |
2021-11-02 |
2023-08-13 |
Not clear |
| Stephen R Edwards, Nemat Khan, Elizabeth J Coulson, Maree T Smit. Comparative studies of glial fibrillary acidic protein and brain-derived neurotrophic factor expression in two transgenic mouse models of Alzheimer's disease. Clinical and experimental pharmacology & physiology. vol 47. issue 10. 2021-10-29. PMID:32542833. |
in alzheimer's disease (ad) glial fibrillary acidic protein (gfap) is expressed by reactive astrocytes surrounding β-amyloid (aβ) plaques, whereas brain-derived neurotrophic factor (bdnf) levels are typically reduced. |
2021-10-29 |
2023-08-13 |
mouse |
| Jin Hee Ki. Brain-derived neurotrophic factor exerts neuroprotective actions against amyloid β-induced apoptosis in neuroblastoma cells. Experimental and therapeutic medicine. vol 8. issue 6. 2021-10-21. PMID:25371750. |
alzheimer's disease (ad) brains demonstrate decreased levels of brain-derived neurotrophic factor (bdnf) and increased levels of β-amyloid peptide (aβ), which is neurotoxic. |
2021-10-21 |
2023-08-13 |
Not clear |
| Shuo Li, Galit Weinstein, Habil Zare, Alexander Teumer, Uwe Völker, Nele Friedrich, Maria J Knol, Claudia L Satizabal, Vladislav A Petyuk, Hieab H H Adams, Lenore J Launer, David A Bennett, Philip L De Jager, Hans J Grabe, M Arfan Ikram, Vilmundur Gudnason, Qiong Yang, Sudha Seshadr. The genetics of circulating BDNF: towards understanding the role of BDNF in brain structure and function in middle and old ages. Brain communications. vol 2. issue 2. 2021-10-16. PMID:33345186. |
substantial amounts of bdnf are present in peripheral blood, and may serve as biomarkers for alzheimer's disease incidence as well as targets for intervention to reduce alzheimer's disease risk. |
2021-10-16 |
2023-08-13 |
Not clear |
| Yiyuan Xia, Zhi-Hao Wang, Pai Liu, Laura Edgington-Mitchell, Xia Liu, Xiao-Chuan Wang, Keqiang Y. TrkB receptor cleavage by delta-secretase abolishes its phosphorylation of APP, aggravating Alzheimer's disease pathologies. Molecular psychiatry. vol 26. issue 7. 2021-10-12. PMID:32782380. |
bdnf and its high-affinity receptor trkb are reduced in alzheimer's disease (ad), contributing to progressive cognitive decline. |
2021-10-12 |
2023-08-13 |
mouse |
| Hanan Polansky, Benjamin Gora. How an increase in the copy number of HSV-1 during latency can cause Alzheimer's disease: the viral and cellular dynamics according to the microcompetition model. Journal of neurovirology. 2021-10-12. PMID:34635992. |
third, we describe how an increase in this copy number can reduce the concentration of the nmda receptor subunits nr1 and nr2b (grin1 and grin2b genes), and brain derived neurotrophic factor (bdnf), which can cause an impaired synaptic plasticity, aβ accumulation and eventually alzheimer's disease. |
2021-10-12 |
2023-08-13 |
Not clear |
| Luke Ney, Kim Felmingham, David S Nichols, Allison Matthew. Brain-derived neurotropic factor and cortisol levels negatively predict working memory performance in healthy males. Neurobiology of learning and memory. vol 175. 2021-09-27. PMID:32871254. |
there is now significant literature suggesting that increasing brain-derived neurotropic factor (bdnf) signalling may improve memory-related disorders such as alzheimer's disease. |
2021-09-27 |
2023-08-13 |
Not clear |
| Noor Azila Ismail, Mohammad Farris Iman Leong Abdullah, Rohayu Hami, Hazwani Ahmad Yuso. A narrative review of brain-derived neurotrophic factor (BDNF) on cognitive performance in Alzheimer's disease. Growth factors (Chur, Switzerland). vol 38. issue 3-4. 2021-09-22. PMID:33427532. |
a narrative review of brain-derived neurotrophic factor (bdnf) on cognitive performance in alzheimer's disease. |
2021-09-22 |
2023-08-13 |
Not clear |
| Sara Galle, Silvan Licher, Maarten Milders, Jan Berend Deijen, Erik Scherder, Madeleine Drent, Arfan Ikram, Cornelia M van Duij. Plasma Brain-Derived Neurotropic Factor Levels Are Associated with Aging and Smoking But Not with Future Dementia in the Rotterdam Study. Journal of Alzheimer's disease : JAD. vol 80. issue 3. 2021-09-14. PMID:33646145. |
alterations in bdnf signaling have been associated with cognitive impairment, dementia, and alzheimer's disease. |
2021-09-14 |
2023-08-13 |
Not clear |
| Marta Balietti, Cinzia Giuli, Tiziana Casoli, Paolo Fabbietti, Fiorenzo Cont. Is Blood Brain-Derived Neurotrophic Factor a Useful Biomarker to Monitor Mild Cognitive Impairment Patients? Rejuvenation research. vol 23. issue 5. 2021-09-07. PMID:32200710. |
cerebral brain-derived neurotrophic factor (bdnf) alterations were evidenced in alzheimer's disease, but the value of blood bdnf in mci is unclear, especially because of the incomplete/incorrect management of the numerous confounding factors unrelated to the disease. |
2021-09-07 |
2023-08-13 |
human |
| Zhi Li, Liangmin Cui, Hongyao Zhao, Jinxin Du, Subash C B Gopinath, Thangavel Lakshmipriya, Xuezhi Xi. Aluminum Microcomb Electrodes on Silicon Wafer for Detecting Val66Met Polymorphism in Brain-Derived Neurotrophic Factor. Developmental neuroscience. vol 43. issue 1. 2021-08-25. PMID:33849012. |
brain-derived neurotrophic factor (bdnf) dysregulation is widely related with various psychiatric and neurological disorders, including schizophrenia, depression, rett syndrome, and addiction, and the available evidence suggests that bdnf is also highly correlated with parkinson's and alzheimer's diseases. |
2021-08-25 |
2023-08-13 |
Not clear |
| Mingyue Wang, Yuhuan Xie, Dongdong Qi. Proteolytic cleavage of proBDNF to mBDNF in neuropsychiatric and neurodegenerative diseases. Brain research bulletin. vol 166. 2021-08-11. PMID:33202257. |
brain-derived neurotrophic factor (bdnf) is involved in pathophysiological mechanisms in neuropsychiatric diseases, including depression, anxiety, and schizophrenia (sz), as well as neurodegenerative diseases like parkinson's disease (pd) and alzheimer's disease (ad). |
2021-08-11 |
2023-08-13 |
Not clear |
| Ceren Eyileten, Lucia Sharif, Zofia Wicik, Daniel Jakubik, Joanna Jarosz-Popek, Aleksandra Soplinska, Marek Postula, Anna Czlonkowska, Agnieszka Kaplon-Cieslicka, Dagmara Mirowska-Guze. The Relation of the Brain-Derived Neurotrophic Factor with MicroRNAs in Neurodegenerative Diseases and Ischemic Stroke. Molecular neurobiology. vol 58. issue 1. 2021-08-04. PMID:32944919. |
altered levels of bdnf, both in the circulation and in the central nervous system (cns), have been reported to be involved in the pathogenesis of neurodegenerative diseases, including alzheimer's disease (ad), parkinson's disease (pd), amyotrophic lateral sclerosis (als), huntington's disease (hd), multiple sclerosis (ms), and ischemic stroke. |
2021-08-04 |
2023-08-13 |
Not clear |
| David Ruiz-González, Alba Hernández-Martínez, Pedro L Valenzuela, Javier S Morales, Alberto Soriano-Maldonad. Effects of physical exercise on plasma brain-derived neurotrophic factor in neurodegenerative disorders: A systematic review and meta-analysis of randomized controlled trials. Neuroscience and biobehavioral reviews. vol 128. 2021-08-04. PMID:34087277. |
eighteen randomized controlled trials (rct) assessing the effects of exercise interventions versus no exercise on plasma bdnf levels in individuals with neurodegenerative disorders (i.e., multiple sclerosis, parkinson's disease, mild cognitive impairment [mci] and alzheimer's disease) were included. |
2021-08-04 |
2023-08-13 |
Not clear |
| Virendra Tiwari, Akanksha Mishra, Sonu Singh, Sandeep Kumar Mishra, Kiran Kumari Sahu, Parul, Mahesh J Kulkarni, Rakesh Shukla, Shubha Shukl. Protriptyline improves spatial memory and reduces oxidative damage by regulating NFκB-BDNF/CREB signaling axis in streptozotocin-induced rat model of Alzheimer's disease. Brain research. vol 1754. 2021-07-22. PMID:33422534. |
bdnf has been reported to exerts its neuroprotective effect in rodent and primate models as well as in patients of alzheimer's disease (ad). |
2021-07-22 |
2023-08-13 |
rat |
| Samaneh Shamsipour, Gholamreza Sharifi, Farzaneh Taghia. Impact of interval training with probiotic (L. plantarum / Bifidobacterium bifidum) on passive avoidance test, ChAT and BDNF in the hippocampus of rats with Alzheimer's disease. Neuroscience letters. vol 756. 2021-06-22. PMID:33974953. |
impact of interval training with probiotic (l. plantarum / bifidobacterium bifidum) on passive avoidance test, chat and bdnf in the hippocampus of rats with alzheimer's disease. |
2021-06-22 |
2023-08-13 |
rat |
| Halil Aziz Velioglu, Lutfu Hanoglu, Zubeyir Bayraktaroglu, Guven Toprak, Eray Metin Guler, Muhammed Yunus Bektay, Ozlem Mutlu-Burnaz, Burak Yulu. Left lateral parietal rTMS improves cognition and modulates resting brain connectivity in patients with Alzheimer's disease: Possible role of BDNF and oxidative stress. Neurobiology of learning and memory. vol 180. 2021-06-18. PMID:33610772. |
left lateral parietal rtms improves cognition and modulates resting brain connectivity in patients with alzheimer's disease: possible role of bdnf and oxidative stress. |
2021-06-18 |
2023-08-13 |
Not clear |
| Halil Aziz Velioglu, Lutfu Hanoglu, Zubeyir Bayraktaroglu, Guven Toprak, Eray Metin Guler, Muhammed Yunus Bektay, Ozlem Mutlu-Burnaz, Burak Yulu. Left lateral parietal rTMS improves cognition and modulates resting brain connectivity in patients with Alzheimer's disease: Possible role of BDNF and oxidative stress. Neurobiology of learning and memory. vol 180. 2021-06-18. PMID:33610772. |
although rtms has been shown to modify brain-derived neurotrophic factor (bdnf) and oxidative stress levels in many neurological and psychiatric diseases, there is still no study evaluating the relationship between memory performance, bdnf, oxidative stress, and resting brain connectivity following rtms in alzheimer's patients. |
2021-06-18 |
2023-08-13 |
Not clear |
| Lucia Caffino, Francesca Mottarlini, Fabio Fumagall. Born to Protect: Leveraging BDNF Against Cognitive Deficit in Alzheimer's Disease. CNS drugs. vol 34. issue 3. 2021-06-11. PMID:32052374. |
born to protect: leveraging bdnf against cognitive deficit in alzheimer's disease. |
2021-06-11 |
2023-08-13 |
Not clear |
| Clément Barbereau, Alaa Yehya, Michelle Silhol, Nicolas Cubedo, Jean-Michel Verdier, Tangui Maurice, Mireille Rosse. Neuroprotective brain-derived neurotrophic factor signaling in the TAU-P301L tauopathy zebrafish model. Pharmacological research. vol 158. 2021-06-04. PMID:32417505. |
in alzheimer's disease (ad), although the relationship between bdnf and amyloid load has been extensively studied, how tau pathology affects bdnf signaling remains unclear. |
2021-06-04 |
2023-08-13 |
zebrafish |