| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fuqiang Qian, Jian Liu, Hongyu Yang, Haohao Zhu, Zhiqiang Wang, Yue Wu, Zaohuo Chen. Association of plasma brain-derived neurotrophic factor with Alzheimer's disease and its influencing factors in Chinese elderly population. Frontiers in aging neuroscience. vol 14. 2022-11-25. PMID:36425322. |
to explore the association of plasma brain-derived neurotrophic factor (bdnf) levels with alzheimer's disease and its influencing factors. |
2022-11-25 |
2023-08-14 |
Not clear |
| Harikesh Dubey, Anamika Dubey, Kavita Gulati, Arunabha Ra. s-Nitrosoglutathione modulates HDAC2 and BDNF levels in the brain and improves cognitive deficits in experimental model of Alzheimer`s disease in rats. The International journal of neuroscience. 2022-11-21. PMID:36408590. |
s-nitrosoglutathione modulates hdac2 and bdnf levels in the brain and improves cognitive deficits in experimental model of alzheimer`s disease in rats. |
2022-11-21 |
2023-08-14 |
rat |
| Veerta Sharma, Thakur Gurjeet Singh, Amarjot Kaur, Ashi Mannan, Sonia Dhima. Brain-Derived Neurotrophic Factor: A Novel Dynamically Regulated Therapeutic Modulator in Neurological Disorders. Neurochemical research. 2022-10-29. PMID:36308619. |
this article also implicates bdnf in several brain-related disorders, including alzheimer's disease, parkinson's disease, huntington's disease, amyotrophic lateral sclerosis, major depressive disorder, schizophrenia, epilepsy and bipolar disorder. |
2022-10-29 |
2023-08-14 |
Not clear |
| Ya-Jen Chiu, Te-Hsien Lin, Kuo-Hsuan Chang, Wenwei Lin, Hsiu Mei Hsieh-Li, Ming-Tsan Su, Chiung-Mei Chen, Ying-Chieh Sun, Guey-Jen Lee-Che. Novel TRKB agonists activate TRKB and downstream ERK and AKT signaling to protect Aβ-GFP SH-SY5Y cells against Aβ toxicity. Aging. vol 14. issue undefined. 2022-09-28. PMID:36170028. |
decreased bdnf and impaired trkb signaling contribute to neurodegeneration in alzheimer's disease (ad). |
2022-09-28 |
2023-08-14 |
Not clear |
| Yiyi Li, Fang Li, Dongdong Qin, Hongyu Chen, Jianhao Wang, Jiabei Wang, Shafei Song, Chao Wang, Yamei Wang, Songyan Liu, Dandan Gao, Zhi-Hao Wan. The role of brain derived neurotrophic factor in central nervous system. Frontiers in aging neuroscience. vol 14. 2022-09-26. PMID:36158555. |
this review is to provide a comprehensive assessment of the current knowledge and future directions in bdnf-associated research in the central nervous system (cns), with an emphasis on the physiological and pathological functions of bdnf as well as its potential treatment effects in cns diseases, including depression, alzheimer's disease, parkinson's disease, huntington's disease, amyotrophic lateral sclerosis, multiple sclerosis, and cerebral ischemic stroke. |
2022-09-26 |
2023-08-14 |
Not clear |
| Xiuming Li, Peiyan Tian, Xinmin H. Association of Met/Val polymorphism of BDNF gene with Alzheimer's disease in Chinese patients. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 4. 2022-08-21. PMID:35988269. |
association of met/val polymorphism of bdnf gene with alzheimer's disease in chinese patients. |
2022-08-21 |
2023-08-14 |
Not clear |
| Xiuming Li, Peiyan Tian, Xinmin H. Association of Met/Val polymorphism of BDNF gene with Alzheimer's disease in Chinese patients. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 4. 2022-08-21. PMID:35988269. |
in alzheimer's, changes of nucleotide 196 (g> a) or valine polymorphism of 66-methionine in the bdnf gene is a risk factor for brain-derived neurogenic factors. |
2022-08-21 |
2023-08-14 |
Not clear |
| Xiuming Li, Peiyan Tian, Xinmin H. Association of Met/Val polymorphism of BDNF gene with Alzheimer's disease in Chinese patients. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 4. 2022-08-21. PMID:35988269. |
in general, increasing the accumulation of valine/methionine polymorphism of the bdnf gene in alzheimer's patients compared to control can indicate the role of this polymorphism. |
2022-08-21 |
2023-08-14 |
Not clear |
| Sandra Domitrovic Spudic, Matea Nikolac Perkovic, Suzana Uzun, Gordana Nedic Erjavec, Oliver Kozumplik, Dubravka Svob Strac, Ninoslav Mimica, Nela Piva. Reduced plasma BDNF concentration and cognitive decline in veterans with PTSD. Psychiatry research. vol 316. 2022-08-12. PMID:35961151. |
the aim of this study was to evaluate cognitive deterioration and plasma bdnf concentration in 120 veterans with combat related ptsd, 120 healthy controls, 47 subjects with mild cognitive impairment (mci) and 76 patients with alzheimer's disease (ad), and to assess if plasma bdnf concentration might be used as biomarker of cognitive deterioration. |
2022-08-12 |
2023-08-14 |
human |
| Rajeev Joshi, Stephen R J Salto. Neurotrophin Crosstalk in the Etiology and Treatment of Neuropsychiatric and Neurodegenerative Disease. Frontiers in molecular neuroscience. vol 15. 2022-08-01. PMID:35909451. |
this article reviews the current progress in our understanding of the mechanisms by which growth factors, including brain-derived neurotrophic factor (bdnf) and vascular endothelial growth factor (vegf), and select neurotrophin-regulated gene products, such as vgf (non-acronymic) and vgf-derived neuropeptides, function in the central nervous system (cns) to modulate neuropsychiatric and neurodegenerative disorders, with a discussion of the possible therapeutic applications of these growth factors to major depressive disorder (mdd) and alzheimer's disease (ad). |
2022-08-01 |
2023-08-14 |
human |
| Andra Ionescu-Tucker, Liqi Tong, Nicole C Berchtold, Carl W Cotma. Inhibiting BDNF Signaling Upregulates Hippocampal H3K9me3 in a Manner Dependent On Frontiers in aging. vol 3. 2022-07-13. PMID:35821854. |
inhibiting bdnf signaling upregulates hippocampal h3k9me3 in a manner dependent on histone modifications are key contributors to the cognitive decline that occurs in aging and alzheimer's disease. |
2022-07-13 |
2023-08-14 |
mouse |
| Shu-Hui Dou, Yu Cui, Shu-Ming Huang, Bo Zhan. The Role of Brain-Derived Neurotrophic Factor Signaling in Central Nervous System Disease Pathogenesis. Frontiers in human neuroscience. vol 16. 2022-07-11. PMID:35814950. |
recent studies have found abnormal levels of brain-derived neurotrophic factor (bdnf) in a variety of central nervous system (cns) diseases (e.g., stroke, depression, anxiety, alzheimer's disease, and parkinson's disease). |
2022-07-11 |
2023-08-14 |
Not clear |
| Khairunnuur Fairuz Azman, Rahimah Zakari. Recent Advances on the Role of Brain-Derived Neurotrophic Factor (BDNF) in Neurodegenerative Diseases. International journal of molecular sciences. vol 23. issue 12. 2022-06-24. PMID:35743271. |
changes in bdnf levels and signaling pathways have been identified in several neurodegenerative diseases, including alzheimer's disease, parkinson's disease, and huntington's disease, and have been linked with the symptoms and course of these diseases. |
2022-06-24 |
2023-08-14 |
Not clear |
| Alexander G Lucaci, Michael J Notaras, Sergei L Kosakovsky Pond, Dilek Cola. The evolution of BDNF is defined by strict purifying selection and prodomain spatial coevolution, but what does it mean for human brain disease? Translational psychiatry. vol 12. issue 1. 2022-06-22. PMID:35732627. |
bdnf has been implicated in a variety of brain disorders such as neurodevelopmental disorders (e.g., autism spectrum disorder), neuropsychiatric disorders (e.g., anxiety, depression, ptsd, and schizophrenia), and various neurodegenerative disorders (e.g., parkinson's, alzheimer's, etc.). |
2022-06-22 |
2023-08-14 |
human |
| Mohsen Sheykhhasan, Razieh Amini, Sara Soleimani Asl, Massoud Saidijam, Seyed Mahmoud Hashemi, Rezvan Najaf. Neuroprotective effects of coenzyme Q10-loaded exosomes obtained from adipose-derived stem cells in a rat model of Alzheimer's disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 152. 2022-06-09. PMID:35679720. |
according to the findings of this study, exo+ coq10 enhanced cognition and memory deficiency in alzheimer's disease by boosting bdnf and sox2 levels in the hippocampus. |
2022-06-09 |
2023-08-14 |
rat |
| Joost M Riphagen, Roy W E van Hooren, Gunter Kenis, Frans R J Verhey, Heidi I L Jacob. Distinct Patterns Link the BDNF Val66Met Polymorphism to Alzheimer's Disease Pathology. Journal of Alzheimer's disease : JAD. 2022-06-06. PMID:35662115. |
distinct patterns link the bdnf val66met polymorphism to alzheimer's disease pathology. |
2022-06-06 |
2023-08-14 |
Not clear |
| Joost M Riphagen, Roy W E van Hooren, Gunter Kenis, Frans R J Verhey, Heidi I L Jacob. Distinct Patterns Link the BDNF Val66Met Polymorphism to Alzheimer's Disease Pathology. Journal of Alzheimer's disease : JAD. 2022-06-06. PMID:35662115. |
we used cerebrospinal fluid (csf) amyloid-β (aβ)42 and phosphorylated tau (p-tau) to investigate associations with bdnf polymorphisms and modifications by apoe ɛ4 or inflammation in a memory clinic population (n = 114; subjective cognitive decline, mild cognitive impairment, alzheimer's disease). |
2022-06-06 |
2023-08-14 |
Not clear |
| Abdallah Mohammad Ibrahim, Lalita Chauhan, Aditi Bhardwaj, Anjali Sharma, Faizana Fayaz, Bhumika Kumar, Mohamed Alhashmi, Noora AlHajri, Md Sabir Alam, Faheem Hyder Potto. Brain-Derived Neurotropic Factor in Neurodegenerative Disorders. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625880. |
bdnf has been linked to the pathology of the most common neurodegenerative disorders, such as alzheimer's and parkinson's disease. |
2022-05-28 |
2023-08-13 |
Not clear |
| Darren Ty, Barbara Kania, Alexis Sotelo, Jonathan Wisc. Gut Dysbiosis: A Review of the Effects of a High-Fat Diet on Iron Regulation and Brain-Derived Neurotrophic Factor (BDNF) Expression in the Brain-Gut Axis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35556900. |
furthermore, in events such as aging, decreased levels of bdnf is associated with cognitive decline and increased susceptibility to neurodegenerative diseases such as alzheimer's disease (ad). |
2022-05-13 |
2023-08-13 |
human |
| Sanjay Arora, Takahisa Kanekiyo, Jagdish Sing. Functionalized nanoparticles for brain targeted BDNF gene therapy to rescue Alzheimer's disease pathology in transgenic mouse model. International journal of biological macromolecules. 2022-04-04. PMID:35378156. |
functionalized nanoparticles for brain targeted bdnf gene therapy to rescue alzheimer's disease pathology in transgenic mouse model. |
2022-04-04 |
2023-08-13 |
mouse |