| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Francesco Angelucci, Katerina Veverova, Alžbeta Katonová, Martin Vyhnalek, Jakub Hor. Serum PAI-1/BDNF Ratio Is Increased in Alzheimer's Disease and Correlates with Disease Severity. ACS omega. vol 8. issue 39. 2023-10-09. PMID:37810633. |
tpa/plasmin not only prevents the accumulation of β-amyloid in the brain but also is involved in the synthesis of the brain-derived neurotrophic factor (bdnf), a neurotrophin whose levels are reduced in alzheimer. |
2023-10-09 |
2023-10-15 |
Not clear |
| Francesco Angelucci, Katerina Veverova, Alžbeta Katonová, Martin Vyhnalek, Jakub Hor. Serum PAI-1/BDNF Ratio Is Increased in Alzheimer's Disease and Correlates with Disease Severity. ACS omega. vol 8. issue 39. 2023-10-09. PMID:37810633. |
in the present study, we compared bdnf serum levels in alzheimer patients with dementia to those in alzheimer patients with amnestic mild cognitive impairment and to cognitively healthy controls. |
2023-10-09 |
2023-10-15 |
Not clear |
| Francesco Angelucci, Katerina Veverova, Alžbeta Katonová, Martin Vyhnalek, Jakub Hor. Serum PAI-1/BDNF Ratio Is Increased in Alzheimer's Disease and Correlates with Disease Severity. ACS omega. vol 8. issue 39. 2023-10-09. PMID:37810633. |
our results showed that bdnf serum levels are lower (13.7% less) and pai-1 levels are higher in alzheimer patients with dementia than in alzheimer patients with amnestic mild cognitive impairment patients (23% more) or controls (36% more). |
2023-10-09 |
2023-10-15 |
Not clear |
| Francesco Angelucci, Katerina Veverova, Alžbeta Katonová, Martin Vyhnalek, Jakub Hor. Serum PAI-1/BDNF Ratio Is Increased in Alzheimer's Disease and Correlates with Disease Severity. ACS omega. vol 8. issue 39. 2023-10-09. PMID:37810633. |
our results suggest that increased pai-1 levels in alzheimer, by impairing the production of the bdnf, are implicated in disease progression. |
2023-10-09 |
2023-10-15 |
Not clear |
| Bhavana Yerraguravagari, Naga Pavani Penchikala, Aravinda Sai Kolusu, Grandhi Sandeep Ganesh, Prasad Konduri, Kumar V S Nemmani, Pavan Kumar Samudral. Montelukast Ameliorates Scopolamine-induced Alzheimer's Disease: Role on Cholinergic Neurotransmission, Antioxidant Defence System, Neuroinflammation and Expression of BDNF. CNS & neurological disorders drug targets. 2023-10-02. PMID:37779395. |
montelukast ameliorates scopolamine-induced alzheimer's disease: role on cholinergic neurotransmission, antioxidant defence system, neuroinflammation and expression of bdnf. |
2023-10-02 |
2023-10-07 |
Not clear |
| Deborah A Deliyannides, Jamie A Graff, Izael Niño, Seonjoo Lee, Mustafa M Husain, Brent P Forester, Elizabeth Crocco, Ipsit V Vahia, Davangere P Devanan. Effects of lithium on serum Brain-Derived Neurotrophic Factor in Alzheimer's patients with agitation. International journal of geriatric psychiatry. vol 38. issue 9. 2023-09-21. PMID:37732619. |
little is known, however, about the effects of lithium on bdnf in alzheimer's dementia (ad). |
2023-09-21 |
2023-10-07 |
human |
| Meng-Ju Tsai, Yung-Shuan Lin, Chun-Yu Chen, Wei-Ju Lee, Jong-Ling Fu. Serum brain-derived neurotrophic factor levels as a predictor for Alzheimer disease progression. Journal of the Chinese Medical Association : JCMA. 2023-09-15. PMID:37713318. |
brain-derived neurotrophic factor (bdnf) has been implicated in the pathophysiology of alzheimer's disease (ad), and decreased peripheral levels of this protein are associated with an increased risk of developing the disease. |
2023-09-15 |
2023-10-07 |
Not clear |
| Meysam Amidfar, Michelle Lima Garcez, Gholamreza Askari, Mohammad Bagherniya, Fariborz Khorvash, Sahar Golpour Hamedani, Jade de Oliveir. Role of BDNF signaling in the neuroprotective and memory-enhancing effects of flavonoids in Alzheimer's Disease. CNS & neurological disorders drug targets. 2023-09-13. PMID:37702162. |
role of bdnf signaling in the neuroprotective and memory-enhancing effects of flavonoids in alzheimer's disease. |
2023-09-13 |
2023-10-07 |
Not clear |
| Ana Salomé Correia, Armando Cardoso, Nuno Val. BDNF Unveiled: Exploring Its Role in Major Depression Disorder Serotonergic Imbalance and Associated Stress Conditions. Pharmaceutics. vol 15. issue 8. 2023-08-26. PMID:37631295. |
brain-derived neurotrophic factor (bdnf) is a neurotrophin that plays a significant role in the survival and development of neurons, being involved in several diseases such as alzheimer's disease and major depression disorder. |
2023-08-26 |
2023-09-07 |
human |
| Simone Tambaro, Sumonto Mitra, Ruchi Gera, Bengt Linderoth, Lars U Wahlberg, Taher Darreh-Shori, Homira Behbahani, Per Nilsson, Maria Eriksdotte. Feasibility and therapeutical potential of local intracerebral encapsulated cell biodelivery of BDNF to App Alzheimer's research & therapy. vol 15. issue 1. 2023-08-21. PMID:37596686. |
feasibility and therapeutical potential of local intracerebral encapsulated cell biodelivery of bdnf to app alzheimer's disease (ad) is an age-related disease characterized by altered cognition, neuroinflammation, and neurodegeneration against which there is presently no effective cure. |
2023-08-21 |
2023-09-07 |
mouse |
| Ahmad Mobed, Saeid Charsouei, Yalda Yazdani, Morad Kohandel Gargari, Ali Ahmadalipour, Seyyedeh Reyhaneh Sadremousavi, Maryam Farrahizadeh, Ali Shahbazi, Maryam Haghan. Biosensors, Recent Advances in Determination of BDNF and NfL. Cellular and molecular neurobiology. 2023-08-21. PMID:37605014. |
key biomarkers such as brain derived neurotrophic factor (bdnf) and neurofilament light chain (nfl) play important roles in the development and progression of many neurological diseases, including multiple sclerosis, alzheimer's disease, and parkinson's disease. |
2023-08-21 |
2023-09-07 |
Not clear |
| Guangxing Wang, Jianxin Han, Xin Meng, Seong Su Kang, Xia Liu, Yi Eve Sun, Qian Luo, Keqiang Y. Zein-Based Nanoparticles Improve the Therapeutic Efficacy of a TrkB Agonist toward Alzheimer's Disease. ACS chemical neuroscience. 2023-08-16. PMID:37583253. |
the brain-derived neurotrophic factor (bdnf)/trkb pathway plays a crucial role in neural plasticity and neuronal survival but is often deficient in neurodegenerative diseases like alzheimer's disease (ad). |
2023-08-16 |
2023-09-07 |
mouse |
| Mahmoud Hosseini, Fatemeh Mansouritorghabeh, Farimah Beheshti, Fatemeh Shahidpour, Fatemeh Forouzanfar, Arezoo Rajabia. Capparis spinosa Promoted BDNF and Antioxidant Enzyme Levels to Protect Against Learning and Memory Deficits Induced by Scopolamine. Central nervous system agents in medicinal chemistry. 2023-08-11. PMID:37563815. |
alzheimer's disease (ad) is a major neurodegenerative disorder with multiple manifestations, including oxidative stress, brain-derived neurotrophic factor (bdnf) depletion, and cholinergic dysfunction. |
2023-08-11 |
2023-08-16 |
rat |
| Shuangshuang Yang, Lei Fan, Rui Zhang, Chenghuan Song, Jiyun Shi, Jing Wang, Pingao Zhang, Hao Wang, Yongfang Zhan. Smilagenin induces expression and epigenetic remodeling of BDNF in alzheimer's disease. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 118. 2023-07-27. PMID:37499345. |
smilagenin induces expression and epigenetic remodeling of bdnf in alzheimer's disease. |
2023-07-27 |
2023-08-14 |
Not clear |
| Wanbing Wang, Yanzhong Li, Fangling Ma, Xuan Sheng, Kai Chen, Rengong Zhuo, Chen Wang, Honghua Zheng, Yun-Wu Zhang, Guojun Bu, Xiao-Fen Chen, Li Zhon. Microglial repopulation reverses cognitive and synaptic deficits in an Alzheimer's disease model by restoring BDNF signaling. Brain, behavior, and immunity. 2023-07-23. PMID:37482204. |
microglial repopulation reverses cognitive and synaptic deficits in an alzheimer's disease model by restoring bdnf signaling. |
2023-07-23 |
2023-08-14 |
mouse |
| Ram Kumar Manthari, Prathyusha Koyya, Santhi Latha Pandrang. Brain-Derived Neurotrophic Factor - The Protective Agent Against Neurological Disorders. CNS & neurological disorders drug targets. 2023-06-08. PMID:37287291. |
the pathophysiology of some neurodegenerative diseases, including alzheimer's, parkinson's, schizophrenia, and huntington's, has been linked to bdnf. |
2023-06-08 |
2023-08-14 |
Not clear |
| Chiara Criscuolo, Elissavet Chartampila, Stephen D Ginsberg, Helen E Scharfma. Stability of dentate gyrus granule cell mossy fiber BDNF protein expression with age and resistance of granule cells to Alzheimer's disease neuropathology in a mouse model. bioRxiv : the preprint server for biology. 2023-05-23. PMID:37214931. |
stability of dentate gyrus granule cell mossy fiber bdnf protein expression with age and resistance of granule cells to alzheimer's disease neuropathology in a mouse model. |
2023-05-23 |
2023-08-14 |
mouse |
| Chiara Criscuolo, Elissavet Chartampila, Stephen D Ginsberg, Helen E Scharfma. Stability of dentate gyrus granule cell mossy fiber BDNF protein expression with age and resistance of granule cells to Alzheimer's disease neuropathology in a mouse model. bioRxiv : the preprint server for biology. 2023-05-23. PMID:37214931. |
hippocampal bdnf has been implicated alzheimer's disease (ad) because hippocampal levels in ad patients and ad animal models are consistently downregulated, suggesting that reduced bdnf contributes to ad. |
2023-05-23 |
2023-08-14 |
mouse |
| Hironori Nakayama, Daisuke Ihara, Mamoru Fukuchi, Kazufumi Toume, Chisato Yuri, Masaaki Tsuda, Naotoshi Shibahara, Akiko Tabuch. The extract based on the Kampo formula daikenchuto (Da Jian Zhong Tang) induces Bdnf expression and has neurotrophic effects in cultured cortical neurons. Journal of natural medicines. 2023-05-06. PMID:37148454. |
reductions in brain-derived neurotrophic factor (bdnf) expression levels have been reported in the brains of patients with neurological disorders such as alzheimer's disease. |
2023-05-06 |
2023-08-14 |
Not clear |
| Ye Ji Lee, Ye Ji Jeong, Eun Ji Kang, Beom Seok Kang, Song Hee Lee, You Jin Kim, Seong Su Kang, Sang Won Suh, Eun Hee Ah. GAP-43 closely interacts with BDNF in hippocampal neurons and is associated with Alzheimer's disease progression. Frontiers in molecular neuroscience. vol 16. 2023-05-05. PMID:37143467. |
gap-43 closely interacts with bdnf in hippocampal neurons and is associated with alzheimer's disease progression. |
2023-05-05 |
2023-08-14 |
Not clear |