All Relations between neurotransmitter and acetylcholine

Publication Sentence Publish Date Extraction Date Species
Farida Begum, Najeeb Ur Rehman, Ajmal Khan, Sajid Iqbal, Rehan Zafar Paracha, Jalal Uddin, Ahmed Al-Harrasi, Muhammad Arif Lodh. 2-Mercaptobenzimidazole clubbed hydrazone for Alzheimer's therapy: Frontiers in pharmacology. vol 13. 2022-09-05. PMID:36059999. it is a multifactorial disease, developed by the breakdown of the neurotransmitter acetylcholine via acetylcholinesterase (ache). 2022-09-05 2023-08-14 Not clear
Meng Nie, Na Chen, Huanhuan Pang, Tao Jiang, Wei Jiang, Panwen Tian, LiAng Yao, Yangzi Chen, Ralph J DeBerardinis, Weimin Li, Qitao Yu, Caicun Zhou, Zeping H. Targeting acetylcholine signaling modulates persistent drug tolerance in EGFR-mutant lung cancer and impedes tumor relapse. The Journal of clinical investigation. 2022-09-01. PMID:36048538. here, through integration of metabolomics and transcriptomics, we found that the neurotransmitter acetylcholine (ach) was specifically accumulated in dtp cells, and illustrated that treatment with egfr-tki heightens the expression of the rate-limiting enzyme choline acetyltransferase (chat) in ach biosynthesis via yap mediation. 2022-09-01 2023-08-14 Not clear
Honghua Zhang, Yan Peng, Linsheng Zhuo, Yuying Wang, Guo Zeng, Shuzhi Wang, Lin Long, Xuelin Li, Zhen Wan. Recent advance on pleiotropic cholinesterase inhibitors bearing amyloid modulation efficacy. European journal of medicinal chemistry. vol 242. 2022-08-31. PMID:36044812. due to the hugely important roles of neurotransmitter acetylcholine (ach) and amyloid-β (aβ) in the pathogenesis of alzheimer's disease (ad), the development of multi-target directed ligands (mtdls) focused on cholinesterase (che) and aβ becomes one of the most attractive strategies for combating ad. 2022-08-31 2023-08-14 Not clear
Yasir Hasan Siddique, Falaq Naz, Rahul, Himanshi Varshne. Comparative study of rivastigmine and galantamine on the transgenic Current research in pharmacology and drug discovery. vol 3. 2022-08-22. PMID:35992376. the accumulation of amyloid plaques and neurofibrillary tangles leads to the loss of neurons including the cholinergic neurons thus decreasing the levels of acetylcholine (a neurotransmitter). 2022-08-22 2023-08-14 Not clear
Letícia A Nascimento, Érica C M Nascimento, João B L Martin. In silico study of tacrine and acetylcholine binding profile with human acetylcholinesterase: docking and electronic structure. Journal of molecular modeling. vol 28. issue 9. 2022-08-10. PMID:35947248. in this way, we performed a set of theoretical tests of tacrine ligand and acetylcholine neurotransmitter against the human acetylcholinesterase enzyme. 2022-08-10 2023-08-14 human
Patrick S R Davidson, Galit Karpov, Lauriane Giguère, Alex W Castro, François Trembla. Older adults' episodic memory is related to a neurophysiological marker of brain cholinergic activity. Experimental brain research. 2022-07-30. PMID:35907032. episodic memory is vulnerable to aging and may be influenced by age-related decline in the neurotransmitter acetylcholine. 2022-07-30 2023-08-14 Not clear
Dominik Szwajgier, Ewa Baranowska-Wójcik, Anna Winiarska-Mieczan, Dorota Gajowniczek-Ałas. Honeys as Possible Sources of Cholinesterase Inhibitors. Nutrients. vol 14. issue 14. 2022-07-27. PMID:35889933. alzheimer's disease (ad) is a progressive neurodegenerative disease characterised by low levels of the neurotransmitter (acetylcholine), oxidative stress, and inflammation of the central nervous system. 2022-07-27 2023-08-14 Not clear
Katharina Rump, Caroline Holtkamp, Lars Bergmann, Hartmuth Nowak, Matthias Unterberg, Jennifer Orlowski, Patrick Thon, Zainab Bazzi, Maha Bazzi, Michael Adamzik, Björn Koos, Tim Rahme. Midazolam impacts acetyl-And butyrylcholinesterase genes: An epigenetic explanation for postoperative delirium? PloS one. vol 17. issue 7. 2022-07-08. PMID:35802656. since delirium is associated with a malfunction of the neurotransmitter acetylcholine, midazolam appears to interfere with its proper metabolism, which can be triggered by epigenetic modifications. 2022-07-08 2023-08-14 human
Martha Velueta-Viveros, Macarena Martínez-Bailén, Adrián Puerta, Laura L Romero-Hernández, Vladimír Křen, Penélope Merino-Montiel, Sara Montiel-Smith, Miguel X Fernandes, Antonio J Moreno-Vargas, José M Padrón, Óscar López, José G Fernández-Bolaño. Carbohydrate-derived bicyclic selenazolines as new dual inhibitors (cholinesterases/OGA) against Alzheimer's disease. Bioorganic chemistry. vol 127. 2022-07-02. PMID:35779403. in particular, we have focused our attention on modulating the activity of cholinesterases (ache, buche) in order to restore the levels of the neurotransmitter acetylcholine, and of o-glcnacase (oga), which is associated with hyperphosphorylation of tau protein, in turn related to the formation of neurofibrillary tangles in the brain. 2022-07-02 2023-08-14 Not clear
Asaad Khalid, Mohnad Abdalla, Maria Saeed, Muhammad Nabeel Ghayur, Surya Kant Kalauni, Mohammed Albratty, Hassan A Alhazmi, Mohammed Ahmed Mesaik, Anwarul Hassan Gilani, Zaheer Ul-Ha. Sarcorucinine-D Inhibits Cholinesterases and Calcium Channels: Molecular Dynamics Simulation and In Vitro Mechanistic Investigations. Molecules (Basel, Switzerland). vol 27. issue 11. 2022-06-10. PMID:35684298. ache plays an essential role in the nervous system by catalyzing the hydrolysis of the neurotransmitter acetylcholine. 2022-06-10 2023-08-14 Not clear
Yan-Ling Su, Dong Liu, Yao-Jie Liu, Yang-Lin Ji, Gui-Shan Liu, Ji-Li-Te Wang, Biao Wang, Hao Wan. Phlorizin alleviates cholinergic memory impairment and regulates gut microbiota in d-galactose induced mice. Experimental gerontology. 2022-06-06. PMID:35660419. furthermore, a neurotransmitter of acetylcholine (ach) was enhanced, while acetylcholinesterase (ache) activity was inhibited by phlorizin administration. 2022-06-06 2023-08-14 mouse
Solveig Tiepolt, Philipp M Meyer, Marianne Patt, Winnie Deuther-Conrad, Swen Hesse, Henryk Barthel, Osama Sabr. PET Imaging of Cholinergic Neurotransmission in Neurodegenerative Disorders. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. vol 63. issue Suppl 1. 2022-06-01. PMID:35649648. as a neuromodulator, the neurotransmitter acetylcholine plays an important role in cognitive, mood, locomotor, sleep/wake, and olfactory functions. 2022-06-01 2023-08-13 Not clear
Waisley Yang, Rohit Singla, Oshin Maheshwari, Christine J Fontaine, Joana Gil-Mohape. Alcohol Use Disorder: Neurobiology and Therapeutics. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625928. ethanol exerts its toxicity through changes to multiple neurotransmitter systems, including serotonin, dopamine, gamma-aminobutyric acid, glutamate, acetylcholine, and opioid systems. 2022-05-28 2023-08-13 Not clear
Tomasz Tuzimski, Anna Petruczyni. Determination of Anti-Alzheimer's Disease Activity of Selected Plant Ingredients. Molecules (Basel, Switzerland). vol 27. issue 10. 2022-05-28. PMID:35630702. one of the most important therapeutic strategies is controlling the level of acetylcholine-a neurotransmitter in cholinergic synapses-by blocking the degradation of acetylcholine using acetylcholinesterase inhibitors such as tacrine, galantamine, donepezil and rivastigmine. 2022-05-28 2023-08-13 Not clear
Ning-Xin Ma, Brendan Puls, Gong Che. Transcriptomic analyses of NeuroD1-mediated astrocyte-to-neuron conversion. Developmental neurobiology. 2022-05-24. PMID:35606902. neurod family members (neurod1/2/6) and signaling pathways (wnt, mapk, camp) as well as neurotransmitter receptors (acetylcholine, somatostatin, dopamine) were also significantly upregulated. 2022-05-24 2023-08-13 Not clear
Sarah Könemann, Melissa von Wyl, Colette Vom Ber. Zebrafish Larvae Rapidly Recover from Locomotor Effects and Neuromuscular Alterations Induced by Cholinergic Insecticides. Environmental science & technology. 2022-05-16. PMID:35575681. owing to the importance of acetylcholine as a neurotransmitter, many insecticides target the cholinergic system. 2022-05-16 2023-08-13 zebrafish
Kritika Kumari, Laishram R Sing. Trimethylamine N-oxide might impair cholinergic system by affecting the structural integrity of Acetylcholinesterase. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555536. acetylcholinesterase (ache) is an important enzyme responsible for the breakdown of neurotransmitter, acetylcholine and therefore plays a crucial role in neuronal plasticity. 2022-05-13 2023-08-13 human
Piyali Dasgupta, Stephen D Richbart, Austin T Akers, Jamie R Friedman, Sarah L Miles, Eric W Bow, John M Rimoldi, Yi Charlie Che. The choline acetyltransferase inhibitor BW813U inhibits angiogenesis and tumor growth in human lung adenocarcinoma. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35555890. the endogenous ligand for nicotine is the neurotransmitter acetylcholine (ach). 2022-05-13 2023-08-13 mouse
Pawel Dobrzy. CoA in Health and Disease. International journal of molecular sciences. vol 23. issue 8. 2022-04-23. PMID:35457189. coenzyme a (coa) and its thioester derivatives are crucial components of numerous biosynthetic and degradative pathways of the cellular metabolism (including fatty acid synthesis and oxidation, the krebs cycle, ketogenesis, cholesterol and acetylcholine biosynthesis, amino acid degradation, and neurotransmitter biosynthesis), post-translational modifications of proteins, and the regulation of gene expression [...]. 2022-04-23 2023-08-13 Not clear
Quan Feng Liu, Hoon Choi, Taekwon Son, Young- Mi Kim, Suganya Kanmani, Young- Won Chin, Seung-Nam Kim, Kwang Ki Kim, Kyu-Won Kim, Byung-Soo Ko. Co-treatment with the herbal medicine SIP3 and donepezil improves memory and depression in the mouse model of Alzheimer's disease. Current Alzheimer research. 2022-04-15. PMID:35422218. alzheimer's disease (ad) is a lethal, progressive neurodegenerative disorder that has been linked to a deficiency of the neurotransmitter, acetylcholine. 2022-04-15 2023-08-13 mouse