All Relations between neurotransmitter and acetylcholine

Publication Sentence Publish Date Extraction Date Species
Bhuvaneswari Sivaraman, Vijaykumar R, Bala Aakash Velmurugan, Ramalakshmi Nataraja. Acetylcholinesterase Enzyme Inhibitor Molecules with Therapeutic Potential for Alzheimer's Disease. CNS & neurological disorders drug targets. 2021-11-23. PMID:34602041. acetylcholinesterase (ache), hydrolase enzyme, regulates the hydrolysis of acetylcholine neurotransmitter in the neurons. 2021-11-23 2023-08-13 Not clear
Gloria E Uwaya, Omolola E Fayem. Enhanced Electrocatalytic Detection of Choline Based on CNTs and Metal Oxide Nanomaterials. Molecules (Basel, Switzerland). vol 26. issue 21. 2021-11-18. PMID:34770919. choline is an officially established essential nutrient and precursor of the neurotransmitter acetylcholine. 2021-11-18 2023-08-13 Not clear
Rosana Banzato, Nathalia M Pinheiro, Clarice R Olivo, Fernanda R Santana, Fernanda D T Q S Lopes, Luciana C Caperuto, Niels O Câmara, Milton A Martins, Iolanda F L C Tibério, Marco Antônio M Prado, Vânia F Prado, Carla M Prad. Long-term endogenous acetylcholine deficiency potentiates pulmonary inflammation in a murine model of elastase-induced emphysema. Scientific reports. vol 11. issue 1. 2021-11-15. PMID:34354132. acetylcholine (ach), the neurotransmitter of the cholinergic system, regulates inflammation in several diseases including pulmonary diseases. 2021-11-15 2023-08-13 mouse
Jason M Kinchen, Robert P Mohney, Kirk L Pappa. Long-Chain Acylcholines Link Butyrylcholinesterase to Regulation of Non-neuronal Cholinergic Signaling. Journal of proteome research. 2021-11-11. PMID:34758617. acylcholines are comprised of an acyl chain esterified to a choline moiety; acetylcholine is the best-characterized member of this class, functioning as a neurotransmitter in the central and peripheral nervous systems as well as an inhibitor of cytokine production by macrophages and other innate immune cells. 2021-11-11 2023-08-13 Not clear
Jiyeon Han, Zhi Du, Mi Hee Li. Mechanistic Insight into the Design of Chemical Tools to Control Multiple Pathogenic Features in Alzheimer's Disease. Accounts of chemical research. vol 54. issue 20. 2021-11-10. PMID:34606227. finally, the loss of cholinergic transmission mediated by the neurotransmitter acetylcholine (ach) contributes to cognitive deficits observed in ad.in this account, we illustrate the design principles for small-molecule-based chemical tools with reactivities against metal-free aβ, metal-bound aβ, ros, and ache. 2021-11-10 2023-08-13 Not clear
Yoshihiko Kakinum. Significance of vagus nerve function in terms of pathogenesis of psychosocial disorders. Neurochemistry international. vol 143. 2021-11-04. PMID:33307153. the neurotransmitter acetylcholine, released from the cholinergic system including vn, has been known to play an anti-inflammatory role through the efferent pathways in regulating peripheral inflammatory responses profoundly involved in the pathogenesis of diseases. 2021-11-04 2023-08-13 Not clear
Katarzyna M Targowska-Duda, Barbara Budzynska, Agnieszka Michalak, Artur Wnorowski, Claus J Loland, Maciej Maj, Dina Manetti, Maria Novella Romanelli, Krzysztof Jozwiak, Grazyna Biala, Hugo R Aria. Type I and type II positive allosteric modulators of α7 nicotinic acetylcholine receptors induce antidepressant-like activity in mice by a mechanism involving receptor potentiation but not neurotransmitter reuptake inhibition. Correlation with mTOR intracellular pathway activation. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 52. 2021-11-01. PMID:34237657. the aim of this study is to determine whether type i and type ii positive allosteric modulators (pams) of α7 nicotinic acetylcholine receptors (nachrs) induce antidepressant-like activity in mice after acute, subchronic, and chronic treatments, and to assess whether α7-pams inhibit neurotransmitter transporters and activate mtor (mammalian target of rapamycin) and/or erk (extracellular signal-regulated protein kinases) signaling. 2021-11-01 2023-08-13 mouse
Zheng Wang, Adoulaye Issotina Zibrila, Shuhua Liu, Gongxiao Zhao, Yubei Li, Jingning Xu, Dan Liu, Chunfang Li, Weiyi Feng, Jinjun Li. Acetylcholine ameliorated TNF-α-induced primary trophoblast malfunction via muscarinic receptors†. Biology of reproduction. vol 103. issue 6. 2021-10-29. PMID:32902620. numerous studies have shown that acetylcholine (ach), the principal vagal neurotransmitter, plays a crucial role in attenuating oxidative stress, inflammation, and apoptosis in a variety of human diseases. 2021-10-29 2023-08-13 human
Nan Wang, Yaojun Cai, Fen Wang, Xianzhong Zeng, Xuemei Jia, Fangbiao Tao, Defa Zh. Effects of thyroxin and donepezil on hippocampal acetylcholine content and syntaxin-1 and munc-18 expression in adult rats with hypothyroidism. Experimental and therapeutic medicine. vol 7. issue 3. 2021-10-21. PMID:24520241. the aim of the present study was to investigate the effects of adult-onset hypothyroidism on the expression levels of the synaptic proteins syntaxin-1 and munc-18, as well as the content of the neurotransmitter acetylcholine (ach) in the hippocampus. 2021-10-21 2023-08-12 rat
Aijaz Ahmad Malik, Suvash Chandra Ojha, Nalini Schaduangrat, Chanin Nantasenama. ABCpred: a webserver for the discovery of acetyl- and butyryl-cholinesterase inhibitors. Molecular diversity. 2021-10-05. PMID:34609711. the deficiency of the cholinergic neurotransmitter known as acetylcholine (ach) is associated with ad. 2021-10-05 2023-08-13 Not clear
Wanwei Zheng, Huan Song, Zhongguang Luo, Hao Wu, Lin Chen, Yuedi Wang, Haoshu Cui, Yufei Zhang, Bangting Wang, Wenshuai Li, Yao Liu, Jun Zhang, Yiwei Chu, Feifei Luo, Jie Li. Acetylcholine ameliorates colitis by promoting IL-10 secretion of monocytic myeloid-derived suppressor cells through the nAChR/ERK pathway. Proceedings of the National Academy of Sciences of the United States of America. vol 118. issue 11. 2021-09-23. PMID:33836585. as a result, acetylcholine (ach), a major neurotransmitter of the nervous system synthesized by chat, was greatly reduced in colon tissues of both ibd patients and colitis mice. 2021-09-23 2023-08-13 mouse
Oksana Gerlits, Matthew P Blakeley, David A Keen, Zoran Radić, Andrey Kovalevsk. Room temperature crystallography of human acetylcholinesterase bound to a substrate analogue 4K-TMA: Towards a neutron structure. Current research in structural biology. vol 3. 2021-09-21. PMID:34541552. the active center geometry of ache, already highly evolved for the efficient catalysis, was thus indicative of only minor conformational adjustments to accommodate the tetrahedral intermediate in the hydrolysis of the neurotransmitter acetylcholine (ach). 2021-09-21 2023-08-13 human
Masayuki Yamaga, Toshihiro Imada, Hiroko Tani, Shigeru Nakamura, Ayanori Yamaki, Kazuo Tsubot. Acetylcholine and Royal Jelly Fatty Acid Combinations as Potential Dry Eye Treatment Components in Mice. Nutrients. vol 13. issue 8. 2021-09-15. PMID:34444696. rj contains acetylcholine, which is a major cholinergic neurotransmitter, and a unique set of fatty acids with c 8 to 12 chains, which are expected to be associated with health benefits. 2021-09-15 2023-08-13 mouse
O A Ojiakor, R J Rylet. Modulation of sodium-coupled choline transporter CHT function in health and disease. Neurochemistry international. vol 140. 2021-09-02. PMID:32768485. the sodium-coupled high-affinity choline transporter cht plays a critical role in acetylcholine (ach) synthesis by taking up the substrate choline from the synaptic cleft after neurotransmitter release; this conservation mechanism is the rate-limiting step for production of ach, thereby facilitating communication by subsequent action potentials. 2021-09-02 2023-08-13 mouse
Christian Humpe. NGF Released from Blood Cells or Collagen Hydrogels as a Therapeutic Target in Alzheimer's Disease? Advances in experimental medicine and biology. vol 1331. 2021-08-31. PMID:34453299. acetylcholine is the most important neurotransmitter for memory, and cholinergic neurons selectively degenerate in ad, and a loss of acetylcholine directly correlates with cognitive decline. 2021-08-31 2023-08-13 Not clear
Nikolina Maček Hrvat, Zrinka Kovari. Counteracting poisoning with chemical warfare nerve agents. Arhiv za higijenu rada i toksikologiju. vol 71. issue 4. 2021-08-30. PMID:33410774. phosphylation of the pivotal enzyme acetylcholinesterase (ache) by nerve agents (nas) leads to irreversible inhibition of the enzyme and accumulation of neurotransmitter acetylcholine, which induces cholinergic crisis, that is, overstimulation of muscarinic and nicotinic membrane receptors in the central and peripheral nervous system. 2021-08-30 2023-08-13 Not clear
María-Ángeles Cortés-Gómez, Esther Llorens-Álvarez, Jordi Alom, Teodoro Del Ser, Jesús Avila, Javier Sáez-Valero, María-Salud García-Aylló. Tau phosphorylation by glycogen synthase kinase 3β modulates enzyme acetylcholinesterase expression. Journal of neurochemistry. vol 157. issue 6. 2021-08-24. PMID:32955735. moreover, in sh-sy5y cells differentiated into neurons by exposure to retinoic acid (10 µm), over-expression of gsk3β and tau provokes an imbalance in cholinergic activity with a decrease in the neurotransmitter acetylcholine in the cell (45 ± 10%). 2021-08-24 2023-08-13 mouse
Bethasiwi Purbasari, Radha Madhyastha, Harishkumar Madhyastha, Queen Intan Nurrahmah, Masugi Maruyama, Yuichi Nakajima, Hiroaki Kataoka, Nozomi Watanab. Retinoic acid attenuates nuclear factor kappaB mediated induction of NLRP3 inflammasome. Pharmacological reports : PR. 2021-08-20. PMID:34415562. acetylcholine (ach), a neurotransmitter and a part of the cholinergic system, can modify immune responses. 2021-08-20 2023-08-13 Not clear
Hog Kwon Kil, Kyung Woon Kim, Da-Hye Lee, So Min Lee, Chang Ho Lee, So Young Ki. Changes in the Gene Expression Profiles of the Inferior Colliculus Following Unilateral Cochlear Ablation in Adult Rats. Biochemical genetics. vol 59. issue 3. 2021-08-17. PMID:33515340. pathway analyses of these 14 genes included 7 genes, namely, amine compound solute carrier (slc)5a7; slc18a3; slc6a5; synaptic vesicle glycoprotein 2c (sv2c); s100 calcium binding protein a10 (s100a10); a gene with sequence similarity to family 111, member a (fam111a); and peripherin (prph), that were related to the acetylcholine neurotransmitter release cycle, slc transporters, and the neurotransmitter release cycle pathways. 2021-08-17 2023-08-13 rat
Alice Powell, Catriona Ireland, Simon J G Lewi. Visual Hallucinations and the Role of Medications in Parkinson's Disease: Triggers, Pathophysiology, and Management. The Journal of neuropsychiatry and clinical neurosciences. vol 32. issue 4. 2021-08-16. PMID:32374649. while dopaminergic medications have long been associated with pd psychosis, a clear causal link has not been established, and other neurotransmitter systems, particularly noradrenaline, serotonin, and acetylcholine, are implicated and important. 2021-08-16 2023-08-13 Not clear