| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ji Seon Kim, Jong Min Kim, Yu Kyeong Kim, Sang Eun Kim, Ji Young Yun, Beom S Jeo. Striatal dopaminergic functioning in patients with sporadic and hereditary spastic paraplegias with parkinsonism. Journal of Korean medical science. vol 28. issue 11. 2014-07-14. PMID:24265532. |
in the present study, the clinical features of patients with ssp/hsp were investigated, and nigrostriatal dopaminergic binding potential was assessed using dopamine transporter (dat) single-photon emission computer tomography (spect). |
2014-07-14 |
2023-08-12 |
human |
| Sven R Suwijn, Kora de Bruin, Rob M A de Bie, Jan Booi. The role of SPECT imaging of the dopaminergic system in translational research on Parkinson's disease. Parkinsonism & related disorders. vol 20 Suppl 1. 2014-07-11. PMID:24262177. |
imaging of the dopaminergic system with single photon emission computed tomography (spect), and particularly of the dopamine transporter (dat) located in the striatum, is a well accepted tool in clinical practice to confirm or exclude loss of nigrostriatal dopamine (da) neurons in patients suspected to suffer from parkinson's disease (pd). |
2014-07-11 |
2023-08-12 |
human |
| Sven R Suwijn, Kora de Bruin, Rob M A de Bie, Jan Booi. The role of SPECT imaging of the dopaminergic system in translational research on Parkinson's disease. Parkinsonism & related disorders. vol 20 Suppl 1. 2014-07-11. PMID:24262177. |
spect techniques were developed successfully to image neurotransmitter systems, including the presynaptic dat and postsynaptic dopamine d2/3 receptors, in rat and mouse models of pd. |
2014-07-11 |
2023-08-12 |
human |
| Sophie Sérrière, Clovis Tauber, Johnny Vercouillie, Denis Guilloteau, Jean-Bernard Deloye, Lucette Garreau, Laurent Galineau, Sylvie Chalo. In vivo PET quantification of the dopamine transporter in rat brain with [¹⁸F]LBT-999. Nuclear medicine and biology. vol 41. issue 1. 2014-07-10. PMID:24210285. |
we examined whether [(18)f]lbt-999 ((e)-n-(4-fluorobut-2-enyl)2β-carbomethoxy-3β-(4'-tolyl)nortropane) is an efficient positron emission tomography (pet) tracer for the quantification of the dopamine transporter (dat) in the healthy rat brain. |
2014-07-10 |
2023-08-12 |
rat |
| Kenneth Marek, John Seibyl, Shirley Eberly, David Oakes, Ira Shoulson, Anthony E Lang, Chris Hyson, Danna Jenning. Longitudinal follow-up of SWEDD subjects in the PRECEPT Study. Neurology. vol 82. issue 20. 2014-07-10. PMID:24759846. |
to compare the clinical and imaging characteristics of those precept (parkinson research examination of cep-1347 trial) subjects with a scan without evidence of dopaminergic deficit (swedd) to those with dopamine transporter (dat) deficit scans at study baseline and during a 22-month follow-up. |
2014-07-10 |
2023-08-13 |
human |
| Liang Liu, Guozhen Yuan, Zaohuo Cheng, Guofu Zhang, Xiaowei Liu, Huifang Zhan. Identification of the mRNA expression status of the dopamine D2 receptor and dopamine transporter in peripheral blood lymphocytes of schizophrenia patients. PloS one. vol 8. issue 9. 2014-07-07. PMID:24086483. |
the aim of this study was to detect the mrna expression levels of the dopamine d2 receptor (drd2) and dopamine transporter (dat) in peripheral blood leukocytes (pbls) of schizophrenia patients and to explore the relationship between the mrna expression levels and the clinical symptoms of schizophrenia. |
2014-07-07 |
2023-08-12 |
Not clear |
| Sucharita S Somkuwar, Chloe J Jordan, Kathleen M Kantak, Linda P Dwoski. Adolescent atomoxetine treatment in a rodent model of ADHD: effects on cocaine self-administration and dopamine transporters in frontostriatal regions. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 13. 2014-07-01. PMID:23822950. |
using the spontaneously hypertensive rat (shr) model of adhd, we reported that adolescent treatment with the stimulant methylphenidate, a dopamine (dat) and norepinephrine (net) transporter inhibitor, enhanced cocaine self-administration during adulthood, and was associated with increased dat function in mpfc. |
2014-07-01 |
2023-08-12 |
rat |
| Shigeyuki Yamamoto, Hiroyuki Ohba, Shingo Nishiyama, Norihiro Harada, Takeharu Kakiuchi, Hideo Tsukada, Edward F Domin. Subanesthetic doses of ketamine transiently decrease serotonin transporter activity: a PET study in conscious monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 13. 2014-07-01. PMID:23880871. |
the effect of ketamine on the serotonin 1a receptor (5-ht1a-r) and dopamine transporter (dat) was also investigated in the same subjects studied with [(11)c]dasb. |
2014-07-01 |
2023-08-12 |
human |
| Rheaclare Fraser, Yongyue Chen, Bipasha Guptaroy, Kathryn D Luderman, Stephanie L Stokes, Asim Beg, Louis J DeFelice, Margaret E Gneg. An N-terminal threonine mutation produces an efflux-favorable, sodium-primed conformation of the human dopamine transporter. Molecular pharmacology. vol 86. issue 1. 2014-06-30. PMID:24753048. |
the dopamine transporter (dat) reversibly transports dopamine (da) through a series of conformational transitions. |
2014-06-30 |
2023-08-13 |
human |
| Nicolas W Schuck, Peter A Frensch, Brit-Maren M Schjeide, Julia Schröder, Lars Bertram, Shu-Chen L. Effects of aging and dopamine genotypes on the emergence of explicit memory during sequence learning. Neuropsychologia. vol 51. issue 13. 2014-06-25. PMID:24035787. |
of specific interest, polymorphisms of the dopamine- and camp-regulated neuronal phosphoprotein (darpp-32, rs907094) and dopamine transporter (dat, vntr) genes showed interactive effects on overall rts and verbal recall of the sequence in older but not in younger adults. |
2014-06-25 |
2023-08-12 |
human |
| Elizabeth D Cummins, Stephen B Griffin, Katherine C Burgess, Daniel J Peterson, Bryce D Watson, Matthew A Buendia, Gregg D Stanwood, Russell W Brow. Methylphenidate place conditioning in adolescent rats: an analysis of sex differences and the dopamine transporter. Behavioural brain research. vol 257. 2014-06-25. PMID:24084582. |
in two experiments, we analyzed the effects of methylphenidate (mph) on conditioned place preference (cpp) in adolescent male and female rats, and the effects of mph on the dopamine transporter (dat). |
2014-06-25 |
2023-08-12 |
rat |
| Elizabeth D Cummins, Stephen B Griffin, Katherine C Burgess, Daniel J Peterson, Bryce D Watson, Matthew A Buendia, Gregg D Stanwood, Russell W Brow. Methylphenidate place conditioning in adolescent rats: an analysis of sex differences and the dopamine transporter. Behavioural brain research. vol 257. 2014-06-25. PMID:24084582. |
analysis of the dat revealed that animals conditioned with the 5mg/kg dose of mph demonstrated a significant decrease of the dopamine transporter (dat) in the nucleus accumbens and striatum compared to controls. |
2014-06-25 |
2023-08-12 |
rat |
| Hee Kyung Park, Sun J Chun. New perspective on parkinsonism in frontotemporal lobar degeneration. Journal of movement disorders. vol 6. issue 1. 2014-06-24. PMID:24868417. |
dopamine transporter (dat) imaging revealed decreased uptake of dat, and imaging findings indicated atrophic changes of the basal ganglia. |
2014-06-24 |
2023-08-13 |
human |
| Ying Liu, Mei Han, Xingdang Liu, Yanping Deng, Yu Li, Jie Yuan, Rongbin Lv, Yuankai Wang, Guangming Zhang, Jinlong Ga. Dopamine transporter availability in heroin-dependent subjects and controls: longitudinal changes during abstinence and the effects of Jitai tablets treatment. Psychopharmacology. vol 230. issue 2. 2014-06-23. PMID:23715641. |
previous imaging studies have indicated that the levels of the dopamine transporter (dat) are reduced in the brains of heroin users. |
2014-06-23 |
2023-08-12 |
human |
| P J Hamilton, N G Campbell, S Sharma, K Erreger, F Herborg Hansen, C Saunders, A N Belovich, M A Sahai, E H Cook, U Gether, H S McHaourab, H J G Matthies, J S Sutcliffe, A Gall. De novo mutation in the dopamine transporter gene associates dopamine dysfunction with autism spectrum disorder. Molecular psychiatry. vol 18. issue 12. 2014-06-23. PMID:23979605. |
the dopamine transporter (dat) is a presynaptic membrane protein that regulates dopaminergic tone in the central nervous system by mediating the high-affinity reuptake of synaptically released da, making it a crucial regulator of da homeostasis. |
2014-06-23 |
2023-08-12 |
human |
| Bianca C Wittmann, Geoffrey C Tan, John E Lisman, Raymond J Dolan, Emrah Düze. Reprint of: DAT genotype modulates striatal processing and long-term memory for items associated with reward and punishment. Neuropsychologia. vol 51. issue 12. 2014-06-15. PMID:24139823. |
to that end, participants were selected on the basis of their genotype for a variable number of tandem repeat polymorphism of the dopamine transporter (dat) gene. |
2014-06-15 |
2023-08-12 |
human |
| M Federici, E C Latagliata, F R Rizzo, A Ledonne, H H Gu, A Romigi, R Nisticò, S Puglisi-Allegra, N B Mercur. Electrophysiological and amperometric evidence that modafinil blocks the dopamine uptake transporter to induce behavioral activation. Neuroscience. vol 252. 2014-06-11. PMID:23933217. |
although the wake-promoting drug modafinil has been shown to bind quite exclusively to the dopamine transporter (dat), its action in the brain has been thought to be partially independent from the facilitation of the dopaminergic signals. |
2014-06-11 |
2023-08-12 |
mouse |
| Cody A Siciliano, Erin S Calipari, Mark J Ferris, Sara R Jone. Biphasic mechanisms of amphetamine action at the dopamine terminal. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 16. 2014-06-06. PMID:24741047. |
the current study has expanded the inventory of amph actions by defining two separate mechanisms of amph effects on [da]o at high and low doses, one dopamine transporter (dat) independent and one dat dependent, respectively. |
2014-06-06 |
2023-08-13 |
mouse |
| Eunkyung Park, Yu Mi Hwang, Chan-Nyoung Lee, Sujin Kim, Sun Young Oh, Young Chul Kim, Jae Gol Choe, Kun Woo Par. Differential Diagnosis of Patients with Inconclusive Parkinsonian Features Using [(18)F]FP-CIT PET/CT. Nuclear medicine and molecular imaging. vol 48. issue 2. 2014-06-06. PMID:24900150. |
we investigated the usefulness of dopamine transporter (dat) imaging for the differential diagnosis of inconclusive parkinsonism using [(18)f]fp-cit pet. |
2014-06-06 |
2023-08-13 |
Not clear |
| F S Hall, K Itokawa, A Schmitt, R Moessner, I Sora, K P Lesch, G R Uh. Decreased vesicular monoamine transporter 2 (VMAT2) and dopamine transporter (DAT) function in knockout mice affects aging of dopaminergic systems. Neuropharmacology. vol 76 Pt A. 2014-06-05. PMID:23978383. |
decreased vesicular monoamine transporter 2 (vmat2) and dopamine transporter (dat) function in knockout mice affects aging of dopaminergic systems. |
2014-06-05 |
2023-08-12 |
mouse |